- PDB-2xd7: Crystal structure of the macro domain of human core histone H2A -
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Basic information
Entry
Database: PDB / ID: 2xd7
Title
Crystal structure of the macro domain of human core histone H2A
Components
CORE HISTONE MACRO-H2A.2
Keywords
DNA BINDING PROTEIN / CHROMOSOMAL PROTEIN / NUCLEOSOME CORE / CHROMATIN REGULATOR / NUCLEUS / DNA-BINDING PROTEIN / PHOSPHOPROTEIN
Function / homology
Function and homology information
negative regulation of transcription of nucleolar large rRNA by RNA polymerase I / sex-chromosome dosage compensation / establishment of protein localization to chromatin / Barr body / positive regulation of keratinocyte differentiation / negative regulation of gene expression, epigenetic / heterochromatin organization / nucleosomal DNA binding / RNA polymerase II transcription regulatory region sequence-specific DNA binding / brain development ...negative regulation of transcription of nucleolar large rRNA by RNA polymerase I / sex-chromosome dosage compensation / establishment of protein localization to chromatin / Barr body / positive regulation of keratinocyte differentiation / negative regulation of gene expression, epigenetic / heterochromatin organization / nucleosomal DNA binding / RNA polymerase II transcription regulatory region sequence-specific DNA binding / brain development / chromatin DNA binding / structural constituent of chromatin / nucleosome / nucleosome assembly / chromosome, telomeric region / transcription cis-regulatory region binding / protein heterodimerization activity / chromatin / negative regulation of transcription by RNA polymerase II / extracellular exosome / nucleoplasm / nucleus Similarity search - Function