登録情報 | データベース: PDB / ID: 2w84 |
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タイトル | Structure of Pex14 in complex with Pex5 |
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要素 | - PEROXISOMAL MEMBRANE PROTEIN PEX14
- PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR
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キーワード | PROTEIN TRANSPORT / ZELLWEGER SYNDROME / ALTERNATIVE SPLICING / PHOSPHOPROTEIN / PROTEIN COMPLEX / DISEASE MUTATION / PEROXISOME / TPR REPEAT / POLYMORPHISM / TRANSLOCATION / PEROXISOME BIOGENESIS DISORDER / PEROXISOME IMPORT / PTS / RECEPTOR-CARGO COMPLEX / PEROXISOME TARGETING SIGNAL |
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機能・相同性 | 機能・相同性情報
peroxisome transport along microtubule / protein import into peroxisome matrix, substrate release / protein import into peroxisome matrix, translocation / peroxisome membrane targeting sequence binding / protein import into peroxisome membrane / peroxisome targeting sequence binding / protein targeting to peroxisome / peroxisome matrix targeting signal-1 binding / peroxisomal importomer complex / microtubule anchoring ...peroxisome transport along microtubule / protein import into peroxisome matrix, substrate release / protein import into peroxisome matrix, translocation / peroxisome membrane targeting sequence binding / protein import into peroxisome membrane / peroxisome targeting sequence binding / protein targeting to peroxisome / peroxisome matrix targeting signal-1 binding / peroxisomal importomer complex / microtubule anchoring / protein import into peroxisome matrix, receptor recycling / protein import into peroxisome matrix / protein import into peroxisome matrix, docking / Class I peroxisomal membrane protein import / protein carrier chaperone / very long-chain fatty acid metabolic process / cerebral cortex neuron differentiation / peroxisome organization / cell development / pexophagy / positive regulation of multicellular organism growth / endoplasmic reticulum organization / mitochondrial membrane organization / peroxisomal membrane / neuromuscular process / beta-tubulin binding / fatty acid beta-oxidation / cerebral cortex cell migration / peroxisomal matrix / protein transmembrane transporter activity / negative regulation of protein-containing complex assembly / Pexophagy / negative regulation of protein binding / Peroxisomal protein import / protein tetramerization / neuron migration / negative regulation of DNA-binding transcription factor activity / fibrillar center / small GTPase binding / cellular response to reactive oxygen species / transcription corepressor activity / peroxisome / E3 ubiquitin ligases ubiquitinate target proteins / protein-macromolecule adaptor activity / microtubule binding / protein-containing complex assembly / signaling receptor binding / negative regulation of DNA-templated transcription / Golgi apparatus / enzyme binding / protein-containing complex / mitochondrion / identical protein binding / membrane / nucleus / cytoplasm / cytosol類似検索 - 分子機能 Peroxisome membrane anchor protein Pex14p, N-terminal / Peroxisomal membrane protein 14 / Pex14 N-terminal domain / PEX5/PEX5L / Tetratricopeptide repeat / Tetratricopeptide repeat / TPR repeat region circular profile. / TPR repeat profile. / Tetratricopeptide repeats / Tetratricopeptide repeat ...Peroxisome membrane anchor protein Pex14p, N-terminal / Peroxisomal membrane protein 14 / Pex14 N-terminal domain / PEX5/PEX5L / Tetratricopeptide repeat / Tetratricopeptide repeat / TPR repeat region circular profile. / TPR repeat profile. / Tetratricopeptide repeats / Tetratricopeptide repeat / Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain / Tetratricopeptide-like helical domain superfamily / Arc Repressor Mutant, subunit A / Winged helix-like DNA-binding domain superfamily / Orthogonal Bundle / Mainly Alpha類似検索 - ドメイン・相同性 Peroxisomal membrane protein PEX14 / Peroxisomal targeting signal 1 receptor類似検索 - 構成要素 |
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生物種 | HOMO SAPIENS (ヒト) |
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手法 | 溶液NMR / torsion angle dynamics |
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データ登録者 | Neufeld, C. / Filipp, F.V. / Simon, B. / Neuhaus, A. / Schueller, N. / David, C. / Kooshapur, H. / Madl, T. / Erdmann, R. / Schliebs, W. ...Neufeld, C. / Filipp, F.V. / Simon, B. / Neuhaus, A. / Schueller, N. / David, C. / Kooshapur, H. / Madl, T. / Erdmann, R. / Schliebs, W. / Wilmanns, M. / Sattler, M. |
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引用 | ジャーナル: EMBO J. / 年: 2009 タイトル: Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19. 著者: Neufeld, C. / Filipp, F.V. / Simon, B. / Neuhaus, A. / Schuller, N. / David, C. / Kooshapur, H. / Madl, T. / Erdmann, R. / Schliebs, W. / Wilmanns, M. / Sattler, M. |
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履歴 | 登録 | 2009年1月9日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2009年2月17日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2013年5月8日 | Group: Derived calculations / Other ...Derived calculations / Other / Structure summary / Version format compliance |
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改定 1.2 | 2018年1月17日 | Group: Database references / カテゴリ: citation / citation_author Item: _citation.journal_abbrev / _citation.journal_id_ISSN ..._citation.journal_abbrev / _citation.journal_id_ISSN / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.title / _citation_author.name |
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改定 1.3 | 2024年5月15日 | Group: Data collection / Database references / Other カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_nmr_software Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_mr / _pdbx_nmr_software.name |
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