PDB-4nj7: PB1 Domain of AtARF7 - SeMet Derivative

Basic information

• Entry: Database: PDB / ID: 4nj7
• Title: PB1 Domain of AtARF7 - SeMet Derivative
• Components: Auxin response factor 7
• Keywords: PROTEIN BINDING / PB1 domain / Beta-grasp fold

Function / homology

Function:

callus formation / lateral root formation / blue light signaling pathway / response to ethylene / gravitropism / lateral root development / phototropism / leaf development / response to auxin / auxin-activated signaling pathway / DNA-binding transcription factor activity / positive regulation of DNA-templated transcription / DNA binding / nucleus

Domain/homology:

Auxin response factor domain / Auxin response factor / Auxin response factor / AUX/IAA domain / AUX/IAA family / B3 DNA binding domain / B3 DNA binding domain / B3 DNA-binding domain profile. / B3 DNA binding domain / DNA-binding pseudobarrel domain superfamily / PB1 domain profile. / PB1 domain / Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 / Ubiquitin-like (UB roll) / Roll / Alpha Beta

Component:

Auxin response factor 7

• Biological species: Arabidopsis thaliana (thale cress)
• Method: X-RAY DIFFRACTION / SYNCHROTRON / SAD / Resolution: 3 Å
• Authors: Korasick, D.A. / Westfall, C.S. / Lee, S.G. / Nanao, M. / Jez, J.M. / Strader, L.C.
• Citation: Journal: Proc.Natl.Acad.Sci.USA / Year: 2014; Title: Molecular basis for AUXIN RESPONSE FACTOR protein interaction and the control of auxin response repression.; Authors: Korasick, D.A. / Westfall, C.S. / Lee, S.G. / Nanao, M.H. / Dumas, R. / Hagen, G. / Guilfoyle, T.J. / Jez, J.M. / Strader, L.C.

History

Deposition	Nov 8, 2013	Deposition site: RCSB / Processing site: RCSB
Revision 1.0	Mar 26, 2014	Provider: repository / Type: Initial release
Revision 1.1	May 14, 2014	Group: Database references
Revision 1.2	Nov 22, 2017	Group: Refinement description / Category: software / Item: _software.name

Assembly

Deposited unit

A: Auxin response factor 7

B: Auxin response factor 7

C: Auxin response factor 7

D: Auxin response factor 7

E: Auxin response factor 7

F: Auxin response factor 7

G: Auxin response factor 7

H: Auxin response factor 7

I: Auxin response factor 7

J: Auxin response factor 7

K: Auxin response factor 7

L: Auxin response factor 7

M: Auxin response factor 7

N: Auxin response factor 7

O: Auxin response factor 7

P: Auxin response factor 7

Summary:

• 177 kDa, 16 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	177,197	16
Polymers	177,197	16
Non-polymers	0	0
Water	0

1

A: Auxin response factor 7

Summary:

• defined by author&software
• 11.1 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	11,075	1
Polymers	11,075	1
Non-polymers	0	0
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Method	PISA

2

B: Auxin response factor 7

Summary:

• defined by author&software
• 11.1 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	11,075	1
Polymers	11,075	1
Non-polymers	0	0
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Method	PISA

3

C: Auxin response factor 7

Summary:

• defined by author&software
• 11.1 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	11,075	1
Polymers	11,075	1
Non-polymers	0	0
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Method	PISA

4

D: Auxin response factor 7

Summary:

• defined by author&software
• 11.1 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	11,075	1
Polymers	11,075	1
Non-polymers	0	0
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Method	PISA

5

E: Auxin response factor 7

Summary:

• defined by author&software
• 11.1 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	11,075	1
Polymers	11,075	1
Non-polymers	0	0
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Method	PISA

6

F: Auxin response factor 7

Summary:

• defined by author&software
• 11.1 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	11,075	1
Polymers	11,075	1
Non-polymers	0	0
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Method	PISA

7

G: Auxin response factor 7

Summary:

• defined by author&software
• 11.1 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	11,075	1
Polymers	11,075	1
Non-polymers	0	0
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Method	PISA

8

H: Auxin response factor 7

Summary:

• defined by author&software
• 11.1 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	11,075	1
Polymers	11,075	1
Non-polymers	0	0
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Method	PISA

9

I: Auxin response factor 7

Summary:

• defined by author&software
• 11.1 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	11,075	1
Polymers	11,075	1
Non-polymers	0	0
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Method	PISA

10

J: Auxin response factor 7

Summary:

• defined by author&software
• 11.1 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	11,075	1
Polymers	11,075	1
Non-polymers	0	0
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Method	PISA

11

K: Auxin response factor 7

Summary:

• defined by author&software
• 11.1 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	11,075	1
Polymers	11,075	1
Non-polymers	0	0
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Method	PISA

12

L: Auxin response factor 7

Summary:

• defined by author&software
• 11.1 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	11,075	1
Polymers	11,075	1
Non-polymers	0	0
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Method	PISA

13

M: Auxin response factor 7

Summary:

• defined by author&software
• 11.1 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	11,075	1
Polymers	11,075	1
Non-polymers	0	0
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Method	PISA

14

N: Auxin response factor 7

Summary:

• defined by author&software
• 11.1 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	11,075	1
Polymers	11,075	1
Non-polymers	0	0
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Method	PISA

15

O: Auxin response factor 7

Summary:

• defined by author&software
• 11.1 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	11,075	1
Polymers	11,075	1
Non-polymers	0	0
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Method	PISA

16

P: Auxin response factor 7

Summary:

• defined by author&software
• 11.1 kDa, 1 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	11,075	1
Polymers	11,075	1
Non-polymers	0	0
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Method	PISA

Unit cell

Length a, b, c (Å)	150.936, 150.936, 184.236
Angle α, β, γ (deg.)	90.00, 90.00, 120.00
Int Tables number	146
Space group name H-M	H3

Components

#1: Protein

A B C D E F G H I J K L M N O P
Auxin response factor 7 / Auxin-responsive protein IAA21/IAA23/IAA25 / Protein BIPOSTO / Protein NON-PHOTOTROPIC HYPOCOTYL 4 / Protein TRANSPORT INHIBITOR RESPONSE 5

Details:

Mass: 11074.795 Da / Num. of mol.: 16 / Fragment: PB1 Domain (UNP Residues 1036-1126) / Mutation: K1042A, D1092A, D1096A
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Arabidopsis thaliana (thale cress)
Gene: ARF7, BIP, IAA21, IAA23, IAA25, NPH4, TIR5, At5g20730, T1M15.130
Plasmid: pET28a / Production host: Escherichia coli (E. coli) / Strain (production host): BL21(DE3) / References: UniProt: P93022

Experimental details

Experiment

• Experiment: Method: X-RAY DIFFRACTION / Number of used crystals: 1

Sample preparation

• Crystal: Density Matthews: 2.28 ų/Da / Density % sol: 46.03 %
• Crystal grow: Temperature: 277 K / Method: vapor diffusion, hanging drop / pH: 6.5 ; Details: 20% PEG-3350, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K

Data collection

• Diffraction: Mean temperature: 77 K
• Diffraction source: Source: SYNCHROTRON / Site: APS / Beamline: 19-ID / Wavelength: 0.979 Å
• Detector: Type: ADSC QUANTUM 315r / Detector: CCD / Date: Aug 1, 2013
• Radiation: Monochromator: Si 111 / Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
• Radiation wavelength: Wavelength: 0.979 Å / Relative weight: 1
• Reflection: Resolution: 3→47.634 Å / Num. all: 28097 / Num. obs: 28097 / % possible obs: 100 % / Observed criterion σ(F): 0 / Observed criterion σ(I): 0
• Reflection shell: Resolution: 3→3.18 Å / % possible all: 100

Processing

Software

Name	Version	Classification
HKL-3000		data collection
PHENIX		model building
PHENIX	(phenix.refine: 1.7.3_928)	refinement
HKL-3000		data reduction
HKL-3000		data scaling
PHENIX		phasing

Refinement

Method to determine structure: SAD / Resolution: 3→47.6 Å / SU ML: 0.5 / σ(F): 0.3 / Phase error: 32.72 / Stereochemistry target values: MLHL

	Rfactor	Num. reflection	% reflection
Rfree	0.304	1829	6.51 %
Rwork	0.257	-	-
obs	0.261	28097	98.9 %

• Solvent computation: Shrinkage radii: 0.86 Å / VDW probe radii: 1.1 Å / Solvent model: FLAT BULK SOLVENT MODEL / B_sol: 39.57 Ų / k_sol: 0.31 e/ų

Displacement parameters

	Baniso -1	Baniso -2	Baniso -3
1-	2.3781 Å2	-0 Å2	0 Å2
2-	-	2.3781 Å2	-0 Å2
3-	-	-	2.3622 Å2

Refinement step

Cycle: LAST / Resolution: 3→47.6 Å

	Protein	Nucleic acid	Ligand	Solvent	Total
Num. atoms	9822	0	0	0	9822

Refine LS restraints

Refine-ID	Type	Dev ideal	Number
X-RAY DIFFRACTION	f_bond_d	0.025	9980
X-RAY DIFFRACTION	f_angle_d	2.048	13434
X-RAY DIFFRACTION	f_dihedral_angle_d	16.791	3652
X-RAY DIFFRACTION	f_chiral_restr	0.118	1480
X-RAY DIFFRACTION	f_plane_restr	0.007	1706

LS refinement shell

Resolution (Å)	Rfactor Rfree	Num. reflection Rfree	Rfactor Rwork	Num. reflection Rwork	Refine-ID	% reflection obs (%)
3-3.1838	0.3808	137	0.3088	1982	X-RAY DIFFRACTION	96
3.1838-3.2775	0.3586	140	0.3036	1981	X-RAY DIFFRACTION	97
3.2775-3.3832	0.3677	136	0.304	1954	X-RAY DIFFRACTION	97
3.3832-3.5041	0.3609	124	0.2873	2058	X-RAY DIFFRACTION	98
3.5041-3.6444	0.3223	146	0.2864	1993	X-RAY DIFFRACTION	99
3.6444-3.8102	0.3226	136	0.285	2045	X-RAY DIFFRACTION	99
3.8102-4.011	0.3351	132	0.2698	2040	X-RAY DIFFRACTION	100
4.011-4.2621	0.3185	143	0.2376	2064	X-RAY DIFFRACTION	100
4.2621-4.5909	0.2604	153	0.2017	2016	X-RAY DIFFRACTION	100
4.5909-5.0525	0.2631	127	0.2029	2058	X-RAY DIFFRACTION	100
5.0525-5.7825	0.2943	142	0.2475	2050	X-RAY DIFFRACTION	100
5.7825-7.2812	0.2963	156	0.2835	2007	X-RAY DIFFRACTION	100
7.2812-47.6392	0.2802	157	0.2619	2020	X-RAY DIFFRACTION	99

Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

ID	L11 (°2)	L12 (°2)	L13 (°2)	L22 (°2)	L23 (°2)	L33 (°2)	S11 (Å °)	S12 (Å °)	S13 (Å °)	S21 (Å °)	S22 (Å °)	S23 (Å °)	S31 (Å °)	S32 (Å °)	S33 (Å °)	T11 (Å2)	T12 (Å2)	T13 (Å2)	T22 (Å2)	T23 (Å2)	T33 (Å2)	Origin x (Å)	Origin y (Å)	Origin z (Å)
1	3.4636	0.5344	-3.9583	7.8839	-3.3125	5.4839	0.154	0.1103	0.0977	0.6875	0.0555	0.3107	-1.0903	1.8724	0.1323	0.3322	-0.1164	0.0647	0.8223	0.0132	0.4163	-26.3477	139.8168	4.605
2	6.5241	0.1331	2.1313	6.3552	-1.9901	8.3332	-0.0543	-0.2927	0.1614	0.3325	0.2044	0.6121	-0.2679	-0.3717	-0.1733	0.5395	-0.1047	0.2943	0.6224	-0.1239	0.5142	-34.2005	135.903	2.8752
3	9.1235	0.6954	-1.4026	9.1123	5.7732	6.8741	0.4584	-1.4077	-1.656	0.8669	-0.19	-1.5241	0.4104	0.9725	-0.471	0.4816	-0.0038	0.0865	0.6205	-0.0399	0.6218	-28.1934	119.9717	35.7313
4	4.2497	2.9928	-3.093	6.8631	0.2697	4.3289	0.2365	1.339	0.4407	0.3038	1.3473	-0.1877	-0.0305	0.2447	1.6409	0.134	0.1115	0.0973	0.7693	0.1198	0.3329	-37.0785	127.9423	27.6716
5	8.9786	2.8327	-0.5802	8.8669	3.5576	3.5376	0.21	0.4878	1.3802	-1.3082	-0.8561	0.5541	-0.9242	-0.9315	0.4054	0.5637	-0.0705	0.0703	0.7324	0.1815	0.6089	-33.4557	127.9912	29.8948
6	7.9658	-0.3539	1.0337	6.6592	-1.6229	4.4679	-0.6528	0.792	1.2031	-0.7453	0.6483	-1.1422	-0.1359	-0.5724	0.8285	0.4088	0.0606	0.0547	0.5363	-0.1605	0.6008	-17.6139	94.4094	31.4759
7	6.5622	1.6983	0.2699	2.136	0.203	4.7509	-0.7122	1.112	0.1283	-0.1682	-0.2984	0.9099	0.7628	-1.5387	0.0653	0.1205	-0.4908	-0.1268	0.9489	-0.8228	0.6627	-29.0731	90.0046	37.319
8	2.5772	-1.631	-0.8344	6.5833	0.1266	8.6096	0.2974	0.6108	-1.1059	-0.1187	-0.0862	0.5424	1.4063	-0.2978	-0.3562	0.6539	-0.034	0.0282	0.6116	-0.059	0.7522	-17.7641	87.6601	40.9561
9	8.8023	3.9012	-1.3322	2.6603	0.2859	3.8595	-0.9177	1.3066	0.3265	0.5484	0.0818	0.295	-1.3294	-0.4969	-0.6512	0.729	-0.097	0.0179	0.5121	-0.0623	0.4935	-20.8343	101.6502	45.8157
10	3.3786	1.0699	3.4795	7.2894	-4.2128	7.6848	0.4099	-0.3954	2.162	0.7108	0.3105	1.0818	-1.4037	-1.0847	-0.0884	0.5426	-0.1056	0.1978	0.2866	-0.1607	0.8063	-24.1126	97.9018	41.9903
11	1.9993	-5.0421	9.7664	2.9154	-4.0375	6.3015	-0.4201	0.4545	3.3367	0.8309	-0.1245	-0.1858	-1.2902	0.965	1.0917	0.8126	0.2224	0.1883	1.1435	0.0034	0.7339	-5.1266	100.0542	41.0235
12	8.4718	0.6976	-1.3233	2.0055	3.3477	6.1634	0.107	1.0818	0.7925	0.7625	0.0703	-0.538	-0.3975	0.263	-0.2589	0.4228	-0.1462	-0.0244	0.7113	0.345	1.1977	-6.6829	104.6568	-8.3791
13	2.5492	-3.0818	-1.1972	6.177	-0.1475	1.5783	0.4751	0.984	1.1002	0.1748	0.2832	0.693	-0.679	-0.3971	-0.4085	0.5357	0.0624	0.0548	0.8475	0.1903	0.6595	-18.7083	110.6241	-10.3295
14	8.5018	-5.4708	-2.7866	7.0427	4.4829	6.6648	-0.2827	0.4973	0.2625	-1.7952	0.5298	0.7187	-0.2027	0.3907	-0.4427	0.7818	-0.1625	-0.0393	0.5913	0.1856	0.5722	-16.3592	100.1622	-10.2992
15	1.5091	0.0772	-2.0251	4.6512	-1.1747	2.9729	-0.6012	-1.5829	0.7999	-0.3256	-0.0102	0.825	-0.3066	-0.1471	-0.001	-0.0853	0.1352	-0.5282	0.724	0.2857	0.959	-17.6982	101.2068	3.1543
16	6.5774	1.1919	-1.2565	2.7284	1.584	2.6446	-0.047	-1.184	0.2856	0.2529	0.0561	0.7817	-0.0239	-1.4208	-0.0925	0.1684	0.1859	0.05	1.226	0.2452	0.8319	-23.1529	109.2545	0.133
17	7.4717	0.9544	-4.3301	0.6604	-0.5701	2.4839	-1.446	-0.7541	-2.0252	0.5625	0.2325	-0.2052	0.8129	-0.1216	-0.8347	0.6925	-0.065	-0.0666	0.6962	0.1319	0.6804	-9.4476	98.6935	-2.1748
18	4.2283	-3.8092	-1.5191	6.6252	0.6891	0.8846	0.1787	0.8881	0.5397	0.0597	0.1952	-0.3821	0.0903	-0.2772	-0.1993	0.5025	0.0534	-0.0165	0.5661	0.1988	0.8637	-19.9641	97.0492	10.0852
19	5.0752	-0.2738	-0.1086	2.5034	-1.7234	2.0493	0.0136	2.1331	-0.6863	-0.7305	0.1602	0.1382	0.9276	0.1983	-0.3829	0.5262	0.1514	-0.3356	0.6338	0.1159	0.3606	-25.7573	90.8236	10.1013
20	2.4161	-3.6095	-2.2456	5.7522	2.0472	8.6322	-0.2826	-0.2433	-0.9104	-0.3118	-0.6322	1.2108	1.9599	0.4388	0.6111	0.6716	0.0277	0.1005	0.4018	0.1975	0.7464	-19.1972	84.8705	15.4834
21	3.4794	-0.787	-0.5955	1.5831	-0.985	6.2131	1.1649	-0.9915	0.9547	1.1311	-0.1442	0.2553	-0.4792	0.4019	-0.1114	0.526	-0.1959	-0.0185	0.6263	-0.0494	0.4548	-23.3543	94.0059	24.4751
22	0.7117	1.5678	2.3922	7.3996	2.5902	2.0072	-0.1845	-1.9182	2.0467	1.6081	-0.7327	0.9066	-1.0896	-0.4227	0.3881	0.509	-0.2423	0.2017	0.6824	-0.39	1.2711	-29.8194	98.5832	20.0791
23	2.0198	1.1925	-2.7964	5.2867	-1.3859	3.9097	-0.9554	-1.6278	0.756	0.8109	-0.2727	-1.6126	-0.0104	1.2041	-1.524	-0.3462	-0.075	-0.4943	1.0459	0.258	0.8906	-13.1554	90.5554	17.5468
24	1.9469	-0.9124	-0.4576	8.0442	-0.4584	2.0338	0.5607	0.5792	0.24	0.0889	-0.6079	0.9488	0.0495	-1.002	-0.1848	0.4093	-0.1572	0.3188	0.6116	-0.0922	0.5924	-74.0765	105.8166	11.0126
25	5.3032	-1.1191	-3.1175	1.5575	-0.941	3.667	-0.543	-0.6805	0.1205	1.2134	-0.7257	1.2924	0.7828	-0.6817	-4.2808	0.3124	0.1151	0.8828	0.4148	-1.1353	0.0956	-67.9297	116.9364	10.6121
26	3.6059	5.5281	-3.4961	9.5582	-4.5394	4.098	0.8046	-1.2539	0.137	1.9455	-0.8975	-1.1676	-0.7776	0.8396	0.7654	0.4472	-0.1487	0.0186	1.2157	0.052	0.7169	-62.0119	110.6088	9.788
27	3.6897	-1.3689	-4.1433	3.1069	-1.7577	8.8057	-0.3467	-0.5064	0.0294	0.2612	0.3694	-1.3034	0.184	1.6808	-0.3717	0.4164	0.122	0.2018	1.1865	-0.116	1.303	-60.4895	101.7497	8.8357
28	3.1051	2.8231	2.7008	3.8246	1.1662	3.6255	0.8024	0.5745	0.8929	0.1063	0.348	-0.5724	0.7987	0.9639	-0.6152	0.6377	-0.2742	0.1707	0.5573	-0.1827	0.7329	-68.8727	108.5324	-2.4629
29	7.2813	-4.2853	0.1696	2.8773	-1.6226	6.8272	0.5127	1.2288	0.1892	0.3998	-0.4437	-0.5397	-1.1326	0.4779	0.2615	0.396	-0.1284	-0.0778	0.8754	-0.1982	0.6391	-70.5715	112.595	1.4856
30	0.9151	-1.4982	1.0561	9.5317	-5.0526	2.9518	0.1737	1.9935	-1.2264	-2.3343	0.3876	1.2268	0.1936	0.0874	0.2452	1.1006	-0.0352	0.1317	1.1487	-0.4549	1.4114	-71.15	93.8569	-1.4122
31	1.7383	0.6686	-0.567	3.6695	-1.9989	2.1848	0.1786	-0.2462	-1.9063	0.3892	-0.1646	0.2154	-0.0598	-0.3079	-0.2589	0.5698	-0.0723	0.0975	0.3718	0.3352	0.8967	-50.8349	107.1378	45.8552
32	1.9854	-2.8128	3.3665	6.4414	-1.1692	4.4184	0.1496	1.9746	-1.3081	-1.6072	0.3835	1.0219	1.4174	-0.0395	-0.3922	0.8178	-0.0287	0.0634	0.6109	0.1179	0.4314	-47.4611	111.5755	39.0556
33	1.9034	0.5547	1.2059	7.2284	-3.1995	4.6864	0.3245	0.909	0.3128	-0.8433	0.404	0.0613	1.9049	-0.9948	-0.5956	0.8639	-0.3258	-0.2827	0.73	0.33	0.8268	-55.4402	113.4703	34.2737
34	7.2556	2.2071	-4.5501	4.182	0.03	3.4205	0.2413	-0.1822	0.3917	-0.6825	-0.022	1.7928	-0.8193	-0.1578	-0.3278	0.4251	0.037	-0.0104	0.7398	-0.1494	0.6483	-55.9326	117.5821	44.9287
35	7.0673	1.164	-3.5746	3.3826	-0.897	6.1751	0.8742	-1.0169	1.4491	-0.1243	-0.4556	0.2961	-0.9222	0.426	-0.6025	0.6388	0.0177	0.3227	0.5048	0.4046	0.7441	-51.7793	121.2682	50.9583
36	7.4005	0.2722	-4.8406	6.3711	-0.151	3.5736	0.5403	-2.1357	0.2889	1.4863	-0.1221	-0.2973	-0.0816	2.2133	0.0049	0.9082	-0.3743	0.0035	1.0316	0.1594	0.5128	-44.687	116.032	53.04
37	7.4394	-4.2417	6.9886	6.8146	-1.8613	8.3423	-1.1091	-1.8246	0.9923	0.0869	1.4004	1.4247	-1.5513	-0.9912	0.196	0.782	-0.1457	0.0045	0.8662	0.1115	0.7452	-63.1039	118.1335	44.9025
38	7.3163	-0.8699	-1.5093	4.8347	-0.8821	3.6946	0.1426	0.3855	-0.3043	0.1063	0.0667	0.289	-0.0778	-1.3403	-0.4079	0.2721	-0.1706	0.0371	0.6727	-0.0723	0.5565	-51.9949	75.8866	21.5976
39	7.5393	-3.2042	-1.3137	7.0527	3.5229	7.3927	0.9694	2.9138	0.3709	-2.4511	-0.1144	-0.5252	-0.5676	-0.1177	-0.5934	0.6523	-0.0841	0.0012	1.2586	0.0787	1.0219	-45.6063	78.5872	9.9661
40	5.1321	-0.6193	-5.9534	5.5057	0.1906	6.9459	0.5805	0.5178	-0.6018	-1.3629	0.0339	0.3702	-1.1567	-0.8555	-0.8035	0.874	-0.0301	-0.2273	0.5185	-0.1334	0.9585	-43.5607	84.352	16.1552
41	1.7756	0.6069	2.7827	5.2549	-0.2352	7.2697	-0.7924	-0.5552	0.2223	0.6087	-0.3718	-0.045	-1.6252	0.7579	0.7316	0.5421	-0.0823	-0.0869	0.7369	0.032	0.9564	-46.4336	86.605	24.719
42	5.9664	1.1146	3.8208	6.4077	-0.7289	7.9894	-0.7577	0.2231	0.1535	-0.4039	-0.2624	-1.4028	-1.0082	1.7777	0.7073	0.4746	-0.0382	0.2467	0.565	0.2858	0.8822	-36.8151	73.396	18.6511
43	8.7777	0.4525	0.5411	1.679	-0.1088	1.6785	0.4866	1.1057	-1.2684	0.2878	-0.4232	-1.0263	0.9261	0.6312	1.8136	0.7835	0.0905	0.3758	0.4935	0.2327	0.8966	-43.4008	71.5768	19.5046
44	5.5879	-3.7763	1.487	4.2523	-3.7077	4.6884	0.2289	-1.0647	0.0671	-1.2752	0.4287	-0.2398	-1.0603	1.0878	-0.8918	1.1082	-0.0516	-0.1103	1.0902	-0.3771	0.6474	-43.3276	75.1008	35.41
45	5.5182	2.5615	1.4169	9.1281	-2.4496	6.4758	0.7525	-1.7715	0.0406	1.5418	-0.0334	0.6481	-1.2251	0.0392	-0.0913	0.6547	0.0766	0.1048	1.2626	0.0184	0.353	-7.2968	151.8832	31.0681
46	3.2425	-0.1353	1.4103	7.0023	-1.5035	1.9925	0.7412	-0.8215	-0.1455	-0.2534	-1.5912	-1.691	-0.2001	2.437	0.5776	0.3921	0.0755	0.0075	1.3498	-0.0828	1.1232	-0.3461	156.9675	20.5831
47	8.8556	7.2839	-0.2945	6.4128	-1.1774	2.1774	0.3551	0.3427	-1.7764	-0.7583	0.4623	-1.8271	1.5286	1.7078	-0.1086	0.6758	0.3582	-0.1668	1.2661	-0.2441	0.5767	-4.8669	149.8759	18.2794
48	8.8852	2.9922	1.2189	2.8345	-0.8213	2.5782	-0.3579	-0.4235	0.1523	-0.096	0.6946	-0.0401	0.3073	0.5729	-0.4941	0.5988	0.2308	-0.0507	0.498	-0.0091	0.3868	-13.3285	151.4047	22.9496
49	7.2692	-3.0026	3.3033	7.1742	3.4015	5.4155	0.7636	1.3289	1.6711	-0.9289	0.5592	1.2917	-0.9797	0.7964	-1.0888	0.7116	0.0622	0.0178	0.9963	0.0134	1.1977	-10.5518	162.0903	15.3136
50	4.0741	4.1544	-4.4043	2.0055	-2.9024	6.567	0.5232	0.3676	1.0951	0.8673	0.9506	1.7647	-0.7726	-1.3569	-1.0251	1.0899	0.0588	-0.0419	0.9873	0.0394	0.6474	-17.0958	154.3576	27.4422
51	1.8963	-0.6286	1.2546	3.9908	0.8575	4.0079	-0.2538	-0.8276	0.1331	0.5925	-0.5874	1.1735	0.1311	-0.6106	-0.0647	0.2668	0.1169	0.5029	0.9102	-0.4104	0.6809	-45.5644	98.3164	-9.0382
52	6.6774	-3.3513	-0.1551	8.5336	-2.2664	8.3679	0.5083	0.6719	0.5519	0.2883	-0.8833	1.2846	-0.6559	-3.0127	0.4108	0.4399	0.201	-0.1783	1.5824	-0.5559	1.1658	-50.0571	94.1964	-15.3574
53	1.9891	-0.835	-2.1897	2.6078	1.9859	2.9125	-0.2117	0.7415	-0.3637	-2.0622	-0.7508	1.1918	-0.2726	-1.3761	-0.3296	0.9729	0.0159	-0.2047	1.0154	-0.21	0.7252	-45.9014	98.7646	-22.3718
54	5.5979	1.5372	-3.8553	4.1574	-0.5155	3.3476	-0.6657	-0.4558	-1.7406	-0.0583	-0.256	-0.2093	0.7968	-0.4531	1.2256	0.511	-0.1247	0.1532	0.7682	-0.2988	0.7645	-37.8753	87.88	-13.3691
55	6.1531	2.2851	-1.4615	3.7379	-5.6148	9.9493	-0.3154	-0.5259	-0.9281	0.3077	-0.1585	0.5468	1.5259	0.1507	0.1636	0.8021	0.1673	0.2589	0.6186	0.0964	0.8317	-41.2912	89.6	-7.8069
56	8.6396	-0.0472	0.799	3.7185	-2.08	2.1907	-0.7579	0.7412	-1.2021	-1.4588	-0.4087	-1.0285	1.8221	0.5508	0.7955	0.7174	-0.1746	0.1861	0.6988	-0.0972	0.7718	-30.9129	97.047	-22.6376
57	6.4748	-2.2715	2.7846	6.3788	4.3191	6.2096	0.2854	-0.1935	-0.9363	0.0425	1.0998	1.0451	0.4738	-0.421	-0.9447	0.558	-0.0833	0.0345	0.7378	0.4158	0.6723	-48.3166	130.9757	27.7007
58	2.035	2.2637	0.0487	4.4842	-0.7705	1.7556	0.2517	-3.0979	-0.454	1.183	-0.3998	1.4048	0.2042	-0.7399	0.0302	0.7498	0.2903	0.3601	1.4182	0.1786	0.6205	-54.4387	136.2739	31.8784
59	3.2562	-1.4078	-1.6562	6.1725	-0.9709	1.3603	0.169	-1.2078	0.4495	1.2952	1.4894	-0.488	-1.4236	0.692	-0.3784	0.8047	0.0867	0.1297	0.6757	-0.0677	0.3879	-48.8842	142.2053	25.8874
60	0.7204	-0.645	-0.1626	7.6385	-1.2026	0.9385	0.1837	0.558	0.2366	-0.0733	-0.202	-0.8099	0.1366	0.3265	-1.0357	0.1609	0.5517	-0.3901	1.2896	-0.4678	0.8325	-49.3472	134.4852	10.3034
61	8.6861	-2.5367	4.1343	2.8434	0.4494	4.9101	0.7965	-0.1771	-1.9191	0.5988	0.8277	0.9728	0.4796	-1.0996	0.37	0.393	-0.2185	0.0997	0.8192	0.2945	1.0252	-57.0345	133.789	18.2788
62	7.0955	-6.5262	1.5321	6.5085	-0.1948	3.3978	-0.2608	-0.5956	1.7299	-0.4707	0.0735	-1.6598	-0.4128	0.3125	-1.3928	0.6189	0.0421	0.3805	0.9035	0.0069	0.6021	-45.0936	143.5763	22.1438
63	2.9059	0.2968	0.8574	7.9565	-4.2977	3.2604	-0.0232	0.387	-1.0739	1.3993	0.1792	-0.2692	0.2148	-0.2583	-0.216	0.6472	0.0575	0.279	0.6944	-0.0369	0.6739	-73.4594	70.2687	20.6687
64	6.0001	1.1772	-1.8142	1.8985	-0.0604	2.8129	0.2705	2.538	1.0503	-0.6653	0.1928	0.88	-0.0502	-2.2737	0.5649	-0.4569	-0.3517	-0.386	2.0451	0.3142	0.7253	-71.7901	74.1675	9.1498
65	3.0429	4.991	-0.7871	8.8838	0.3318	5.521	0.2103	-0.0947	-0.5446	0.1542	-0.326	0.122	-0.0178	0.9324	-0.3317	0.3299	-0.0527	-0.1799	0.8213	-0.1145	0.549	-62.9879	73.8462	17.1527
66	1.2808	-0.4108	-1.2965	3.6925	0.7605	2.9339	0.4424	-0.306	0.733	0.1891	-0.6667	0.7492	-0.1961	0.028	0.371	0.4749	-0.0314	0.1568	0.9975	-0.1902	0.6463	-71.7772	105.3082	-11.1133
67	3.2443	0.6691	1.5222	1.5234	-0.3149	2.7776	-0.4684	-0.2247	0.4739	0.1491	-0.1156	-0.1098	-0.3282	0.5454	-0.3147	0.3329	-0.1335	-0.4336	1.5695	0.1699	0.6967	-61.9833	112.5567	-16.9423
68	2.3526	-0.7304	1.7204	2.2082	-0.1968	3.0647	0.1577	1.2861	0.1651	-0.2329	0.751	-0.7308	0.7274	1.9948	-0.6764	0.5576	0.284	-0.0583	1.1774	-0.3873	0.6619	-66.435	102.4408	-20.2979
69	6.2153	4.1031	1.4768	3.0827	0.9718	0.4616	-1.0278	0.9536	1.0499	-1.4849	0.3685	0.2221	-0.7071	1.4072	0.2268	0.7155	-0.2815	-0.0014	1.144	0.1351	0.3615	-73.9018	110.3886	-27.6876
70	3.1937	-0.1464	2.4985	8.3843	0.4188	1.9751	-0.7131	0.9228	0.8862	-1.3677	0.3103	0.2979	-0.395	0.7126	-0.826	0.4869	-0.3745	0.2428	1.2584	0.1472	0.8996	-71.0504	113.607	-21.5986
71	2.7746	-1.9238	0.5602	2.159	-1.7119	2.223	0.334	-0.4841	-0.467	0.1625	0.1995	0.1807	1.5169	-1.1208	0.4159	2.0402	-0.7628	-0.7384	1.2785	0.4749	0.0046	-80.6814	96.977	-20.1493
72	3.5003	0.9386	3.2956	3.1601	-2.7716	9.9898	-0.5555	0.4237	-0.8476	0.1401	-0.3586	-0.7156	-1.1078	-0.1969	-0.1479	0.6511	-0.1821	0.2141	0.7523	-0.0229	1.1043	-0.4791	123.8591	27.3594
73	0.832	0.0903	0.3204	0.01	0.0327	0.1265	-0.1698	1.0099	-1.3162	-0.6415	0.7341	-0.9685	0.1029	0.7351	0.1945	0.5594	-0.4118	0.0775	1.0563	-1.0072	2.513	-6.3981	112.1953	21.4945
74	3.8447	1.1562	-0.3306	3.0072	0.8153	2.483	0.487	-0.3394	-2.0506	0.1304	0.0676	-1.5764	0.3704	0.2507	1.1946	0.5858	-0.1696	-0.1339	0.6051	0.5493	2.3417	-2.5951	112.5286	29.9645
75	7.3541	-1.4359	0.3601	1.143	-0.4193	5.3179	0.1807	-0.3699	-1.3557	0.2437	-0.4033	-0.6421	0.2364	0.6566	-0.3475	0.5555	0.1463	-0.4957	0.5832	0.034	1.0956	-7.2877	121.1714	32.0298
76	4.3779	2.0353	-1.243	2.4373	-1.8494	6.3927	-0.4784	0.5394	-1.2034	0.0734	-0.3243	-0.3876	1.2778	0.5224	-0.4799	0.686	0.3116	-0.0336	0.4875	-0.0651	1.035	-16.8857	119.9744	27.8854
77	1.3576	-0.0184	-0.2895	0.0376	-0.117	0.4871	-0.1882	0.2964	-0.4942	-0.1271	-0.001	-0.1248	0.2055	-0.1414	-0.1657	0.6936	-0.0856	1.0607	1.0491	-1.3585	2.0087	-14.758	115.1152	19.7506
78	1.917	0.2124	0.7716	6.9283	3.0457	6.3578	-0.3333	0.3666	0.8165	-0.314	0.3639	-0.7569	-1.5632	-0.751	0.4193	0.4796	0.0984	-0.0238	0.5677	-0.0222	0.9615	-8.369	124.3569	27.3033
79	1.6093	-1.1279	0.5804	6.9695	-3.7128	1.97	0.2217	-0.1277	0.7412	0.2553	-0.6017	0.5731	-0.5494	0.296	-0.4903	1.0617	-0.8806	0.692	0.9362	-0.5166	1.2766	-11.6263	130.0511	40.0991
80	5.2069	2.1002	3.4005	6.3901	2.2468	2.5249	0.3991	-0.2501	0.5709	0.6846	-0.0698	0.5044	-1.226	0.338	0.2246	0.5643	-0.2409	0.1239	0.4997	-0.3311	0.3088	-42.8788	121.215	1.1933
81	8.0828	4.5529	-3.8448	5.5209	-5.7656	7.5951	0.1619	-0.464	1.74	1.1693	0.1593	0.784	-1.3797	-2.3877	-0.4739	0.2134	0.2277	0.1086	1.1954	-0.3317	0.7727	-51.4331	119.8254	-0.2909
82	6.2727	2.0307	-0.024	6.4941	2.2565	4.3714	-0.3938	0.5164	-0.1707	0.4637	0.1775	1.0656	0.0523	-0.5159	0.2744	0.1547	-0.1422	-0.0163	0.369	-0.1475	0.4982	-46.2094	113.2095	-4.6491
83	4.4902	4.6868	-1.2201	8.2196	1.0455	6.582	0.5114	-0.1429	-0.3301	-0.5074	-0.811	-1.1243	0.7919	2.0013	0.7522	0.2977	0.145	0.1288	0.8152	-0.3703	1.1083	-39.8087	114.0622	-2.6596
84	9.2136	-0.3454	4.9172	1.8389	-2.6689	6.0119	-1.446	0.5634	-1.1122	-0.1391	-0.3534	-0.3231	1.5382	0.1024	1.2667	2.0268	-0.1563	0.1481	1.6312	0.2626	0.7362	-40.7058	115.6538	-18.8808
85	5.8777	0.3731	0.6445	4.7711	3.2485	2.2031	0.0907	0.5913	-0.4699	0.0512	-0.1334	0.4055	0.5225	-0.1377	0.2864	0.6568	0.0385	-0.1011	0.5597	-0.1553	0.5255	-18.7377	104.0608	56.1097
86	8.0852	-2.3756	-4.5737	3.0197	3.0276	1.9969	-1.3876	-0.2365	-1.6175	-0.6994	-1.234	0.1766	1.6354	0.5906	0.4399	0.8995	0.0892	0.0041	0.6213	0.2775	0.9227	-12.9285	103.6726	63.1559
87	2.4012	2.0771	0.884	2.7926	2.5709	3.621	-0.4061	-0.8079	0.3799	0.6959	0.2757	-1.2112	-0.557	1.8608	-2.1917	0.6547	0.0688	-0.5853	0.7393	-0.3844	0.7144	-5.2996	106.5008	60.3926
88	1.6548	0.6927	-1.5557	1.8417	-0.2015	3.6562	-0.0532	0.4072	0.1063	-0.1174	0.4278	0.2032	-0.3204	0.1386	1.5071	0.7053	-0.3173	-0.0632	0.9217	0.41	-0.1474	-14.7918	115.2021	57.657
89	0.0545	0.2215	0.2636	2.1128	0.4173	1.651	0.2518	0.4494	-0.0179	-0.1811	0.852	0.6847	-0.5089	-1.0179	-0.858	1.2605	0.2006	-0.6021	0.9681	-0.0441	0.9946	-24.3102	120.6029	54.0535
90	1.0889	0.3182	0.2712	2.207	0.4427	2.0611	-0.1613	0.3023	-0.0228	-0.1134	0.0122	-0.088	-0.6383	-0.3468	-0.2344	1.2461	-0.2452	0.356	0.7527	-0.2908	0.3422	-17.1491	117.7457	63.1093
91	5.0658	2.1253	2.2592	6.9986	7.7286	8.9653	-0.5035	-1.1742	0.2493	-0.594	-1.1907	2.4634	-1.869	-1.716	0.1135	0.698	0.0738	0.3091	0.9442	-0.2963	0.6954	-24.9366	112.5562	63.3967
92	0.983	0.57	0.318	0.9235	-0.2047	0.3639	0.1309	0.2209	-0.0005	-0.3139	0.3779	-0.3037	0.2362	1.1141	-0.2338	1.0059	0.1453	0.196	0.6666	-0.1127	0.2989	-12.6879	112.3541	53.5379

Refinement TLS group

ID	Refine-ID	Refine TLS-ID	Selection details
1	X-RAY DIFFRACTION	1	CHAIN A AND (RESSEQ 1040:1060)
2	X-RAY DIFFRACTION	2	CHAIN A AND (RESSEQ 1061:1123)
3	X-RAY DIFFRACTION	3	CHAIN B AND (RESSEQ 1040:1086)
4	X-RAY DIFFRACTION	4	CHAIN B AND (RESSEQ 1087:1104)
5	X-RAY DIFFRACTION	5	CHAIN B AND (RESSEQ 1105:1124)
6	X-RAY DIFFRACTION	6	CHAIN C AND (RESSEQ 1040:1050)
7	X-RAY DIFFRACTION	7	CHAIN C AND (RESSEQ 1051:1060)
8	X-RAY DIFFRACTION	8	CHAIN C AND (RESSEQ 1061:1090)
9	X-RAY DIFFRACTION	9	CHAIN C AND (RESSEQ 1091:1104)
10	X-RAY DIFFRACTION	10	CHAIN C AND (RESSEQ 1105:1119)
11	X-RAY DIFFRACTION	11	CHAIN C AND (RESSEQ 1120:1126)
12	X-RAY DIFFRACTION	12	CHAIN D AND (RESSEQ 1040:1050)
13	X-RAY DIFFRACTION	13	CHAIN D AND (RESSEQ 1051:1060)
14	X-RAY DIFFRACTION	14	CHAIN D AND (RESSEQ 1061:1090)
15	X-RAY DIFFRACTION	15	CHAIN D AND (RESSEQ 1091:1104)
16	X-RAY DIFFRACTION	16	CHAIN D AND (RESSEQ 1105:1111)
17	X-RAY DIFFRACTION	17	CHAIN D AND (RESSEQ 1112:1123)
18	X-RAY DIFFRACTION	18	CHAIN E AND (RESSEQ 1040:1045)
19	X-RAY DIFFRACTION	19	CHAIN E AND (RESSEQ 1046:1071)
20	X-RAY DIFFRACTION	20	CHAIN E AND (RESSEQ 1072:1091)
21	X-RAY DIFFRACTION	21	CHAIN E AND (RESSEQ 1092:1104)
22	X-RAY DIFFRACTION	22	CHAIN E AND (RESSEQ 1105:1113)
23	X-RAY DIFFRACTION	23	CHAIN E AND (RESSEQ 1114:1123)
24	X-RAY DIFFRACTION	24	CHAIN F AND (RESSEQ 1039:1050)
25	X-RAY DIFFRACTION	25	CHAIN F AND (RESSEQ 1051:1060)
26	X-RAY DIFFRACTION	26	CHAIN F AND (RESSEQ 1061:1071)
27	X-RAY DIFFRACTION	27	CHAIN F AND (RESSEQ 1072:1086)
28	X-RAY DIFFRACTION	28	CHAIN F AND (RESSEQ 1087:1104)
29	X-RAY DIFFRACTION	29	CHAIN F AND (RESSEQ 1105:1119)
30	X-RAY DIFFRACTION	30	CHAIN F AND (RESSEQ 1120:1126)
31	X-RAY DIFFRACTION	31	CHAIN G AND (RESSEQ 1040:1060)
32	X-RAY DIFFRACTION	32	CHAIN G AND (RESSEQ 1061:1071)
33	X-RAY DIFFRACTION	33	CHAIN G AND (RESSEQ 1072:1078)
34	X-RAY DIFFRACTION	34	CHAIN G AND (RESSEQ 1086:1091)
35	X-RAY DIFFRACTION	35	CHAIN G AND (RESSEQ 1092:1104)
36	X-RAY DIFFRACTION	36	CHAIN G AND (RESSEQ 1105:1113)
37	X-RAY DIFFRACTION	37	CHAIN G AND (RESSEQ 1114:1126)
38	X-RAY DIFFRACTION	38	CHAIN H AND (RESSEQ 1040:1050)
39	X-RAY DIFFRACTION	39	CHAIN H AND (RESSEQ 1051:1060)
40	X-RAY DIFFRACTION	40	CHAIN H AND (RESSEQ 1061:1071)
41	X-RAY DIFFRACTION	41	CHAIN H AND (RESSEQ 1072:1086)
42	X-RAY DIFFRACTION	42	CHAIN H AND (RESSEQ 1087:1109)
43	X-RAY DIFFRACTION	43	CHAIN H AND (RESSEQ 1110:1118)
44	X-RAY DIFFRACTION	44	CHAIN H AND (RESSEQ 1119:1126)
45	X-RAY DIFFRACTION	45	CHAIN I AND (RESSEQ 1040:1050)
46	X-RAY DIFFRACTION	46	CHAIN I AND (RESSEQ 1051:1060)
47	X-RAY DIFFRACTION	47	CHAIN I AND (RESSEQ 1061:1071)
48	X-RAY DIFFRACTION	48	CHAIN I AND (RESSEQ 1072:1099)
49	X-RAY DIFFRACTION	49	CHAIN I AND (RESSEQ 1100:1109)
50	X-RAY DIFFRACTION	50	CHAIN I AND (RESSEQ 1110:1126)
51	X-RAY DIFFRACTION	51	CHAIN J AND (RESSEQ 1040:1060)
52	X-RAY DIFFRACTION	52	CHAIN J AND (RESSEQ 1061:1071)
53	X-RAY DIFFRACTION	53	CHAIN J AND (RESSEQ 1072:1086)
54	X-RAY DIFFRACTION	54	CHAIN J AND (RESSEQ 1087:1104)
55	X-RAY DIFFRACTION	55	CHAIN J AND (RESSEQ 1105:1118)
56	X-RAY DIFFRACTION	56	CHAIN J AND (RESSEQ 1119:1124)
57	X-RAY DIFFRACTION	57	CHAIN K AND (RESSEQ 1039:1060)
58	X-RAY DIFFRACTION	58	CHAIN K AND (RESSEQ 1061:1071)
59	X-RAY DIFFRACTION	59	CHAIN K AND (RESSEQ 1072:1091)
60	X-RAY DIFFRACTION	60	CHAIN K AND (RESSEQ 1092:1096)
61	X-RAY DIFFRACTION	61	CHAIN K AND (RESSEQ 1097:1113)
62	X-RAY DIFFRACTION	62	CHAIN K AND (RESSEQ 1114:1123)
63	X-RAY DIFFRACTION	63	CHAIN L AND (RESSEQ 1039:1050)
64	X-RAY DIFFRACTION	64	CHAIN L AND (RESSEQ 1051:1071)
65	X-RAY DIFFRACTION	65	CHAIN L AND (RESSEQ 1072:1124)
66	X-RAY DIFFRACTION	66	CHAIN M AND (RESSEQ 1040:1050)
67	X-RAY DIFFRACTION	67	CHAIN M AND (RESSEQ 1051:1060)
68	X-RAY DIFFRACTION	68	CHAIN M AND (RESSEQ 1061:1091)
69	X-RAY DIFFRACTION	69	CHAIN M AND (RESSEQ 1097:1104)
70	X-RAY DIFFRACTION	70	CHAIN M AND (RESSEQ 1105:1118)
71	X-RAY DIFFRACTION	71	CHAIN M AND (RESSEQ 1119:1123)
72	X-RAY DIFFRACTION	72	CHAIN N AND (RESSEQ 1041:1054)
73	X-RAY DIFFRACTION	73	CHAIN N AND (RESSEQ 1055:1061)
74	X-RAY DIFFRACTION	74	CHAIN N AND (RESSEQ 1062:1071)
75	X-RAY DIFFRACTION	75	CHAIN N AND (RESSEQ 1072:1091)
76	X-RAY DIFFRACTION	76	CHAIN N AND (RESSEQ 1092:1104)
77	X-RAY DIFFRACTION	77	CHAIN N AND (RESSEQ 1105:1111)
78	X-RAY DIFFRACTION	78	CHAIN N AND (RESSEQ 1112:1118)
79	X-RAY DIFFRACTION	79	CHAIN N AND (RESSEQ 1119:1124)
80	X-RAY DIFFRACTION	80	CHAIN O AND (RESSEQ 1040:1060)
81	X-RAY DIFFRACTION	81	CHAIN O AND (RESSEQ 1061:1071)
82	X-RAY DIFFRACTION	82	CHAIN O AND (RESSEQ 1072:1109)
83	X-RAY DIFFRACTION	83	CHAIN O AND (RESSEQ 1110:1118)
84	X-RAY DIFFRACTION	84	CHAIN O AND (RESSEQ 1119:1126)
85	X-RAY DIFFRACTION	85	CHAIN P AND (RESSEQ 1039:1060)
86	X-RAY DIFFRACTION	86	CHAIN P AND (RESSEQ 1061:1071)
87	X-RAY DIFFRACTION	87	CHAIN P AND (RESSEQ 1072:1086)
88	X-RAY DIFFRACTION	88	CHAIN P AND (RESSEQ 1087:1091)
89	X-RAY DIFFRACTION	89	CHAIN P AND (RESSEQ 1092:1096)
90	X-RAY DIFFRACTION	90	CHAIN P AND (RESSEQ 1097:1104)
91	X-RAY DIFFRACTION	91	CHAIN P AND (RESSEQ 1105:1113)
92	X-RAY DIFFRACTION	92	CHAIN P AND (RESSEQ 1114:1119)