+データを開く
-基本情報
登録情報 | データベース: PDB / ID: 2r1b | ||||||
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タイトル | Crystal Structure of rat neurexin 1beta with a splice insert at SS#4 | ||||||
要素 | Neurexin-1-beta | ||||||
キーワード | CELL ADHESION / SPLICING / beta-sandwich | ||||||
機能・相同性 | 機能・相同性情報 protein-containing complex assembly involved in synapse maturation / regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission / positive regulation of presynaptic active zone assembly / cell-cell adhesion involved in synapse maturation / regulation of postsynaptic specialization assembly / protein complex involved in cell-cell adhesion / gephyrin clustering involved in postsynaptic density assembly / type 1 fibroblast growth factor receptor binding / positive regulation of neuromuscular synaptic transmission / guanylate kinase-associated protein clustering ...protein-containing complex assembly involved in synapse maturation / regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission / positive regulation of presynaptic active zone assembly / cell-cell adhesion involved in synapse maturation / regulation of postsynaptic specialization assembly / protein complex involved in cell-cell adhesion / gephyrin clustering involved in postsynaptic density assembly / type 1 fibroblast growth factor receptor binding / positive regulation of neuromuscular synaptic transmission / guanylate kinase-associated protein clustering / neuron to neuron synapse / neuroligin clustering involved in postsynaptic membrane assembly / postsynaptic density protein 95 clustering / cerebellar granule cell differentiation / postsynaptic membrane assembly / synapse maturation / presynaptic membrane assembly / gamma-aminobutyric acid receptor clustering / negative regulation of filopodium assembly / maintenance of synapse structure / vocal learning / neuroligin family protein binding / positive regulation of synapse maturation / positive regulation of fibroblast growth factor receptor signaling pathway / regulation of postsynaptic density assembly / inhibitory synapse / synaptic vesicle clustering / synaptic membrane adhesion / regulation of grooming behavior / neuron cell-cell adhesion / presynapse assembly / receptor localization to synapse / regulation of synaptic vesicle cycle / protein localization to synapse / NMDA glutamate receptor clustering / vocalization behavior / calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules / regulation of AMPA receptor activity / neurotransmitter secretion / filopodium assembly / neuron maturation / acetylcholine receptor binding / positive regulation of synapse assembly / regulation of NMDA receptor activity / heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules / adult behavior / positive regulation of protein kinase A signaling / positive regulation of excitatory postsynaptic potential / social behavior / neuromuscular process controlling balance / regulation of presynapse assembly / excitatory synapse / calcium channel regulator activity / endocytic vesicle / GABA-ergic synapse / prepulse inhibition / axonal growth cone / presynaptic active zone membrane / cell adhesion molecule binding / synapse assembly / cellular response to calcium ion / positive regulation of synaptic transmission, glutamatergic / neuron projection morphogenesis / learning / positive regulation of synaptic transmission, GABAergic / positive regulation of protein localization to plasma membrane / Schaffer collateral - CA1 synapse / establishment of protein localization / neuromuscular junction / positive regulation of neuron projection development / circadian rhythm / transmembrane signaling receptor activity / calcium-dependent protein binding / neuron projection development / positive regulation of peptidyl-serine phosphorylation / presynaptic membrane / chemical synaptic transmission / nuclear membrane / angiogenesis / vesicle / positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / positive regulation of ERK1 and ERK2 cascade / negative regulation of gene expression / signaling receptor binding / neuronal cell body / glutamatergic synapse / calcium ion binding / protein-containing complex binding / positive regulation of gene expression / cell surface / endoplasmic reticulum / signal transduction / protein-containing complex / plasma membrane 類似検索 - 分子機能 | ||||||
生物種 | Rattus norvegicus (ドブネズミ) | ||||||
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.72 Å | ||||||
データ登録者 | Rudenko, G. | ||||||
引用 | ジャーナル: Structure / 年: 2008 タイトル: Regulation of Neurexin 1beta Tertiary Structure and Ligand Binding through Alternative Splicing 著者: Shen, K.C. / Kuczynska, D.A. / Wu, I.J. / Murray, B.H. / Sheckler, L.R. / Rudenko, G. | ||||||
履歴 |
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-構造の表示
構造ビューア | 分子: MolmilJmol/JSmol |
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-ダウンロードとリンク
-ダウンロード
PDBx/mmCIF形式 | 2r1b.cif.gz | 99.4 KB | 表示 | PDBx/mmCIF形式 |
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PDB形式 | pdb2r1b.ent.gz | 74.5 KB | 表示 | PDB形式 |
PDBx/mmJSON形式 | 2r1b.json.gz | ツリー表示 | PDBx/mmJSON形式 | |
その他 | その他のダウンロード |
-検証レポート
文書・要旨 | 2r1b_validation.pdf.gz | 440.1 KB | 表示 | wwPDB検証レポート |
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文書・詳細版 | 2r1b_full_validation.pdf.gz | 446.6 KB | 表示 | |
XML形式データ | 2r1b_validation.xml.gz | 20.4 KB | 表示 | |
CIF形式データ | 2r1b_validation.cif.gz | 30.4 KB | 表示 | |
アーカイブディレクトリ | https://data.pdbj.org/pub/pdb/validation_reports/r1/2r1b ftp://data.pdbj.org/pub/pdb/validation_reports/r1/2r1b | HTTPS FTP |
-関連構造データ
-リンク
-集合体
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非結晶学的対称性 (NCS) | NCSドメイン:
NCSドメイン領域: Ens-ID: 1 / Refine code: 2
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