- PDB-2k2f: Solution structure of Ca2+-S100A1-RyRP12 -
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Basic information
Entry
Database: PDB / ID: 2k2f
Title
Solution structure of Ca2+-S100A1-RyRP12
Components
Protein S100-A1
Ryanodine receptor 1 peptide
Keywords
METAL BINDING PROTEIN / S100 / EF hand / ryanodine receptor / calcium binding / Alternative splicing / Calcium channel / Calcium transport / Glycoprotein / Ion transport / Ionic channel / Membrane / Polymorphism / Transmembrane / Transport / Cytoplasm / Metal-binding / Zinc
Function / homology
Function and homology information
calcium ion transmembrane import into cytosol => GO:0097553 / Stimuli-sensing channels / Regulation of TLR by endogenous ligand / manganese ion transmembrane transport / suramin binding / establishment of protein localization to endoplasmic reticulum / type B pancreatic cell apoptotic process / Purkinje myocyte to ventricular cardiac muscle cell signaling / response to xenobiotic stimulus => GO:0009410 / regulation of SA node cell action potential ...calcium ion transmembrane import into cytosol => GO:0097553 / Stimuli-sensing channels / Regulation of TLR by endogenous ligand / manganese ion transmembrane transport / suramin binding / establishment of protein localization to endoplasmic reticulum / type B pancreatic cell apoptotic process / Purkinje myocyte to ventricular cardiac muscle cell signaling / response to xenobiotic stimulus => GO:0009410 / regulation of SA node cell action potential / regulation of atrial cardiac muscle cell action potential / left ventricular cardiac muscle tissue morphogenesis / organic cyclic compound binding / regulation of AV node cell action potential / positive regulation of ATPase-coupled calcium transmembrane transporter activity / calcium-induced calcium release activity / sarcoplasmic reticulum calcium ion transport / RAGE receptor binding / ventricular cardiac muscle cell action potential / regulation of ventricular cardiac muscle cell action potential / positive regulation of sequestering of calcium ion / embryonic heart tube morphogenesis / cardiac muscle hypertrophy / M band / ryanodine-sensitive calcium-release channel activity / regulation of cardiac muscle contraction by calcium ion signaling / I band / S100 protein binding / response to muscle activity / release of sequestered calcium ion into cytosol by sarcoplasmic reticulum / calcium ion transport into cytosol / response to caffeine / A band / response to redox state / regulation of heart contraction / positive regulation of heart rate / Ion homeostasis / negative regulation of cytosolic calcium ion concentration / positive regulation of sprouting angiogenesis / cellular response to caffeine / protein kinase A regulatory subunit binding / intracellularly gated calcium channel activity / protein kinase A catalytic subunit binding / positive regulation of the force of heart contraction / response to magnesium ion / : / detection of calcium ion / regulation of cardiac muscle contraction / smooth endoplasmic reticulum / regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion / cardiac muscle contraction / release of sequestered calcium ion into cytosol / monoatomic ion transmembrane transport / extrinsic component of cytoplasmic side of plasma membrane / sarcoplasmic reticulum membrane / cellular response to epinephrine stimulus / calcium channel complex / regulation of cytosolic calcium ion concentration / response to muscle stretch / regulation of heart rate / sarcomere / response to nutrient / sarcoplasmic reticulum / calcium-mediated signaling / calcium ion transmembrane transport / calcium channel activity / cytoplasmic vesicle membrane / sarcolemma / Z disc / intracellular calcium ion homeostasis / response to calcium ion / calcium ion transport / calcium-dependent protein binding / : / nuclear envelope / ATPase binding / scaffold protein binding / positive regulation of canonical NF-kappaB signal transduction / calmodulin binding / response to hypoxia / neuron projection / calcium ion binding / positive regulation of cell population proliferation / protein kinase binding / perinuclear region of cytoplasm / enzyme binding / negative regulation of transcription by RNA polymerase II / endoplasmic reticulum / protein homodimerization activity / protein-containing complex / mitochondrion / extracellular space / membrane / identical protein binding / nucleus / plasma membrane / cytoplasm Similarity search - Function
Protein S100-A1 / S-100/ICaBP type calcium binding protein signature. / S100/Calcium binding protein 7/8-like, conserved site / S100/CaBP-9k-type, calcium binding, subdomain / S-100/ICaBP type calcium binding domain / S-100/ICaBP type calcium binding domain / EF hand / Ryanodine receptor, SPRY domain 2 / Ryanodine Receptor TM 4-6 / Ryanodine receptor ...Protein S100-A1 / S-100/ICaBP type calcium binding protein signature. / S100/Calcium binding protein 7/8-like, conserved site / S100/CaBP-9k-type, calcium binding, subdomain / S-100/ICaBP type calcium binding domain / S-100/ICaBP type calcium binding domain / EF hand / Ryanodine receptor, SPRY domain 2 / Ryanodine Receptor TM 4-6 / Ryanodine receptor / Ryanodine receptor, SPRY domain 1 / Ryanodine receptor, SPRY domain 3 / Ryanodine Receptor TM 4-6 / Ryanodine receptor Ryr / RyR domain / RyR/IP3 receptor binding core, RIH domain superfamily / RyR/IP3R Homology associated domain / Inositol 1,4,5-trisphosphate/ryanodine receptor / RIH domain / RyR and IP3R Homology associated / Inositol 1,4,5-trisphosphate/ryanodine receptor / RIH domain / MIR motif / MIR domain / MIR domain profile. / Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases / Mir domain superfamily / SPRY domain / B30.2/SPRY domain / B30.2/SPRY domain profile. / SPRY domain / B30.2/SPRY domain superfamily / Domain in SPla and the RYanodine Receptor. / EF-hand / Recoverin; domain 1 / EF-hand, calcium binding motif / EF-Hand 1, calcium-binding site / EF-hand calcium-binding domain. / EF-hand calcium-binding domain profile. / EF-hand domain / Ion transport domain / Ion transport protein / EF-hand domain pair / Concanavalin A-like lectin/glucanase domain superfamily / Orthogonal Bundle / Mainly Alpha Similarity search - Domain/homology
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