- PDB-2hzm: Structure of the Mediator head subcomplex Med18/20 -
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Entry
Database: PDB / ID: 2hzm
Title
Structure of the Mediator head subcomplex Med18/20
Components
RNA polymerase II mediator complex subunit 18
RNA polymerase II mediator complex subunit 20
Keywords
TRANSCRIPTION / beta barrel / channel
Function / homology
Function and homology information
core mediator complex / negative regulation of ribosomal protein gene transcription by RNA polymerase II / transcription open complex formation at RNA polymerase II promoter / mediator complex / termination of RNA polymerase II transcription / TFIID-class transcription factor complex binding / positive regulation of transcription initiation by RNA polymerase II / RNA polymerase II core promoter sequence-specific DNA binding / RNA polymerase II preinitiation complex assembly / positive regulation of transcription elongation by RNA polymerase II ...core mediator complex / negative regulation of ribosomal protein gene transcription by RNA polymerase II / transcription open complex formation at RNA polymerase II promoter / mediator complex / termination of RNA polymerase II transcription / TFIID-class transcription factor complex binding / positive regulation of transcription initiation by RNA polymerase II / RNA polymerase II core promoter sequence-specific DNA binding / RNA polymerase II preinitiation complex assembly / positive regulation of transcription elongation by RNA polymerase II / transcription coregulator activity / transcription coactivator activity / protein domain specific binding / regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / nucleus Similarity search - Function
q64v53_bacfr protein fold - #20 / TATA-Binding Protein - #180 / q64v53_bacfr protein fold / Mediator of RNA polymerase II transcription subunit 20 / Hypothetical Protein Pfu-838710-001 / Hypothetical Protein Pfu-838710-001 / Mediator complex, subunit Med20 / TATA-binding related factor (TRF) of subunit 20 of Mediator complex / Mediator complex, subunit Med18 / Med18 protein ...q64v53_bacfr protein fold - #20 / TATA-Binding Protein - #180 / q64v53_bacfr protein fold / Mediator of RNA polymerase II transcription subunit 20 / Hypothetical Protein Pfu-838710-001 / Hypothetical Protein Pfu-838710-001 / Mediator complex, subunit Med20 / TATA-binding related factor (TRF) of subunit 20 of Mediator complex / Mediator complex, subunit Med18 / Med18 protein / TATA-Binding Protein / Single Sheet / Beta Barrel / 2-Layer Sandwich / Mainly Beta / Alpha Beta Similarity search - Domain/homology
PHOSPHATE ION / Mediator of RNA polymerase II transcription subunit 18 / Mediator of RNA polymerase II transcription subunit 20 Similarity search - Component
Biological species
Saccharomyces cerevisiae (brewer's yeast)
Method
X-RAY DIFFRACTION / SYNCHROTRON / SAD / Resolution: 2.4 Å
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