登録情報 データベース : PDB / ID : 1zkz 構造の表示 ダウンロードとリンクタイトル Crystal Structure of BMP9 要素Growth/differentiation factor 2 詳細 キーワード HORMONE/GROWTH FACTOR / glycoprotein / growth factor / cytokine / HORMONE-GROWTH FACTOR COMPLEX機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
positive regulation of epithelial cell differentiation / positive regulation of cartilage development / positive regulation of endothelial cell differentiation / positive regulation of bicellular tight junction assembly / Signaling by BMP / cellular response to BMP stimulus / activin receptor signaling pathway / positive regulation of BMP signaling pathway / cartilage development / blood vessel morphogenesis ... positive regulation of epithelial cell differentiation / positive regulation of cartilage development / positive regulation of endothelial cell differentiation / positive regulation of bicellular tight junction assembly / Signaling by BMP / cellular response to BMP stimulus / activin receptor signaling pathway / positive regulation of BMP signaling pathway / cartilage development / blood vessel morphogenesis / negative regulation of endothelial cell migration / branching involved in blood vessel morphogenesis / positive regulation of Notch signaling pathway / negative regulation of DNA replication / negative regulation of endothelial cell proliferation / positive regulation of SMAD protein signal transduction / negative regulation of blood vessel endothelial cell migration / vasculogenesis / BMP signaling pathway / positive regulation of endothelial cell proliferation / protein serine/threonine kinase activator activity / negative regulation of angiogenesis / ossification / cytokine activity / positive regulation of interleukin-8 production / growth factor activity / negative regulation of cell growth / osteoblast differentiation / positive regulation of angiogenesis / angiogenesis / intracellular iron ion homeostasis / transcription by RNA polymerase II / positive regulation of DNA-templated transcription / positive regulation of transcription by RNA polymerase II / extracellular space / extracellular exosome / extracellular region 類似検索 - 分子機能 TGF-beta, propeptide / TGF-beta propeptide / Transforming growth factor beta, conserved site / TGF-beta family signature. / Transforming growth factor-beta-related / Transforming growth factor-beta (TGF-beta) family / Transforming growth factor-beta, C-terminal / Transforming growth factor beta like domain / TGF-beta family profile. / Cystine Knot Cytokines, subunit B ... TGF-beta, propeptide / TGF-beta propeptide / Transforming growth factor beta, conserved site / TGF-beta family signature. / Transforming growth factor-beta-related / Transforming growth factor-beta (TGF-beta) family / Transforming growth factor-beta, C-terminal / Transforming growth factor beta like domain / TGF-beta family profile. / Cystine Knot Cytokines, subunit B / Cystine-knot cytokines / Cystine-knot cytokine / Ribbon / Mainly Beta 類似検索 - ドメイン・相同性生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.33 Å 詳細データ登録者 Brown, M.A. / Zhao, Q. / Baker, K.A. / Naik, C. / Chen, C. / Pukac, L. / Singh, M. / Tsareva, T. / Parice, Y. / Mahoney, A. ...Brown, M.A. / Zhao, Q. / Baker, K.A. / Naik, C. / Chen, C. / Pukac, L. / Singh, M. / Tsareva, T. / Parice, Y. / Mahoney, A. / Roschke, V. / Sanyal, I. / Choe, S. 引用ジャーナル : J.Biol.Chem. / 年 : 2005タイトル : Crystal structure of BMP-9 and functional interactions with pro-region and receptors著者 : Brown, M.A. / Zhao, Q. / Baker, K.A. / Naik, C. / Chen, C. / Pukac, L. / Singh, M. / Tsareva, T. / Parice, Y. / Mahoney, A. / Roschke, V. / Sanyal, I. / Choe, S. 履歴 登録 2005年5月4日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2005年5月24日 Provider : repository / タイプ : Initial release改定 1.1 2008年4月1日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Derived calculations / Version format compliance改定 1.3 2017年10月11日 Group : Refinement description / カテゴリ : software改定 1.4 2023年8月23日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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