- PDB-1ukl: Crystal structure of Importin-beta and SREBP-2 complex -
+
Open data
ID or keywords:
Loading...
-
Basic information
Entry
Database: PDB / ID: 1ukl
Title
Crystal structure of Importin-beta and SREBP-2 complex
Components
Importin beta-1 subunit
Sterol regulatory element binding protein-2
Keywords
PROTEIN TRANSPORT/DNA BINDING PROTEIN / Transcription factor / Nuclear transport factor / HEAT repeat / Helix-Loop-Helix Leucine zipper / PROTEIN TRANSPORT-DNA BINDING PROTEIN COMPLEX
Function / homology
Function and homology information
Regulation of cholesterol biosynthesis by SREBP (SREBF) / SREBP-SCAP-Insig complex / Assembly of the ORC complex at the origin of replication / Apoptosis induced DNA fragmentation / Initiation of Nuclear Envelope (NE) Reformation / positive regulation of cholesterol storage / regulation of cholesterol biosynthetic process / RNA import into nucleus / Interferon alpha/beta signaling / mitotic chromosome movement towards spindle pole ...Regulation of cholesterol biosynthesis by SREBP (SREBF) / SREBP-SCAP-Insig complex / Assembly of the ORC complex at the origin of replication / Apoptosis induced DNA fragmentation / Initiation of Nuclear Envelope (NE) Reformation / positive regulation of cholesterol storage / regulation of cholesterol biosynthetic process / RNA import into nucleus / Interferon alpha/beta signaling / mitotic chromosome movement towards spindle pole / endoplasmic reticulum tubular network / negative regulation of cholesterol efflux / : / regulation of Notch signaling pathway / SREBP signaling pathway / establishment of mitotic spindle localization / astral microtubule organization / regulation of autophagy of mitochondrion / chromatin => GO:0000785 / positive regulation of cholesterol biosynthetic process / cellular response to laminar fluid shear stress / EGR2 and SOX10-mediated initiation of Schwann cell myelination / Regulation of cholesterol biosynthesis by SREBP (SREBF) / importin-alpha family protein binding / ribosomal protein import into nucleus / NLS-dependent protein nuclear import complex / positive regulation of protein targeting to mitochondrion / nuclear import signal receptor activity / nuclear localization sequence binding / mitotic metaphase chromosome alignment / NLS-bearing protein import into nucleus / response to lipid / Maturation of hRSV A proteins / E-box binding / kinesin binding / cellular response to low-density lipoprotein particle stimulus / mitotic spindle assembly / nuclear pore / cellular response to starvation / Neutrophil degranulation / cholesterol metabolic process / Activation of gene expression by SREBF (SREBP) / cholesterol homeostasis / Hsp90 protein binding / ER to Golgi transport vesicle membrane / lipid metabolic process / PPARA activates gene expression / small GTPase binding / DNA-binding transcription repressor activity, RNA polymerase II-specific / positive regulation of miRNA transcription / cytoplasmic stress granule / Transcriptional regulation of white adipocyte differentiation / protein import into nucleus / sequence-specific double-stranded DNA binding / nuclear membrane / protein dimerization activity / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / DNA-binding transcription factor activity / protein domain specific binding / Golgi membrane / intracellular membrane-bounded organelle / protein-containing complex binding / endoplasmic reticulum membrane / regulation of transcription by RNA polymerase II / negative regulation of transcription by RNA polymerase II / endoplasmic reticulum / positive regulation of transcription by RNA polymerase II / protein-containing complex / nucleoplasm / nucleus / cytoplasm / cytosol Similarity search - Function
In the structure databanks used in Yorodumi, some data are registered as the other names, "COVID-19 virus" and "2019-nCoV". Here are the details of the virus and the list of structure data.
Jan 31, 2019. EMDB accession codes are about to change! (news from PDBe EMDB page)
EMDB accession codes are about to change! (news from PDBe EMDB page)
The allocation of 4 digits for EMDB accession codes will soon come to an end. Whilst these codes will remain in use, new EMDB accession codes will include an additional digit and will expand incrementally as the available range of codes is exhausted. The current 4-digit format prefixed with “EMD-” (i.e. EMD-XXXX) will advance to a 5-digit format (i.e. EMD-XXXXX), and so on. It is currently estimated that the 4-digit codes will be depleted around Spring 2019, at which point the 5-digit format will come into force.
The EM Navigator/Yorodumi systems omit the EMD- prefix.
Related info.:Q: What is EMD? / ID/Accession-code notation in Yorodumi/EM Navigator
Yorodumi is a browser for structure data from EMDB, PDB, SASBDB, etc.
This page is also the successor to EM Navigator detail page, and also detail information page/front-end page for Omokage search.
The word "yorodu" (or yorozu) is an old Japanese word meaning "ten thousand". "mi" (miru) is to see.
Related info.:EMDB / PDB / SASBDB / Comparison of 3 databanks / Yorodumi Search / Aug 31, 2016. New EM Navigator & Yorodumi / Yorodumi Papers / Jmol/JSmol / Function and homology information / Changes in new EM Navigator and Yorodumi