+Open data
-Basic information
Entry | Database: PDB / ID: 7k5j | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Title | Structure of an E1-E2-ubiquitin thioester mimetic | ||||||||||||
Components |
| ||||||||||||
Keywords | SIGNALING PROTEIN / CONFORMATIONAL CHANGE / ADENYLATION / THIOESTER TRANSFER / TRANSTHIOESTERIFICATION / ATP-BINDING / UBIQUITIN E2-BINDING / UBIQUITINATION | ||||||||||||
Function / homology | Function and homology information regulation of transcription by galactose / regulation of sulfur amino acid metabolic process / cellular response to methylmercury / Synthesis of active ubiquitin: roles of E1 and E2 enzymes / E1 ubiquitin-activating enzyme / ubiquitin activating enzyme activity / regulation of metabolic process / positive regulation of glucose transmembrane transport / mitotic intra-S DNA damage checkpoint signaling / silent mating-type cassette heterochromatin formation ...regulation of transcription by galactose / regulation of sulfur amino acid metabolic process / cellular response to methylmercury / Synthesis of active ubiquitin: roles of E1 and E2 enzymes / E1 ubiquitin-activating enzyme / ubiquitin activating enzyme activity / regulation of metabolic process / positive regulation of glucose transmembrane transport / mitotic intra-S DNA damage checkpoint signaling / silent mating-type cassette heterochromatin formation / mitochondrial fusion / SCF ubiquitin ligase complex / E2 ubiquitin-conjugating enzyme / SCF-dependent proteasomal ubiquitin-dependent protein catabolic process / ubiquitin conjugating enzyme activity / Antigen processing: Ubiquitination & Proteasome degradation / subtelomeric heterochromatin formation / protein autoubiquitination / regulation of mitotic cell cycle / modification-dependent protein catabolic process / G1/S transition of mitotic cell cycle / protein polyubiquitination / protein tag activity / ubiquitin-protein transferase activity / G2/M transition of mitotic cell cycle / ubiquitin-dependent protein catabolic process / proteasome-mediated ubiquitin-dependent protein catabolic process / DNA replication / chromosome, telomeric region / protein ubiquitination / cell division / mRNA binding / ubiquitin protein ligase binding / DNA damage response / ATP binding / nucleus / cytoplasm Similarity search - Function | ||||||||||||
Biological species | Triticum aestivum (bread wheat) Saccharomyces cerevisiae (brewer's yeast) | ||||||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.42 Å | ||||||||||||
Authors | Yuan, L. / Lv, Z. / Olsen, S.K. | ||||||||||||
Funding support | United States, 3items
| ||||||||||||
Citation | Journal: Nat Commun / Year: 2021 Title: Crystal structures of an E1-E2-ubiquitin thioester mimetic reveal molecular mechanisms of transthioesterification. Authors: Yuan, L. / Lv, Z. / Adams, M.J. / Olsen, S.K. | ||||||||||||
History |
|
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
---|
-Downloads & links
-Download
PDBx/mmCIF format | 7k5j.cif.gz | 3.8 MB | Display | PDBx/mmCIF format |
---|---|---|---|---|
PDB format | pdb7k5j.ent.gz | 3.2 MB | Display | PDB format |
PDBx/mmJSON format | 7k5j.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 7k5j_validation.pdf.gz | 860.7 KB | Display | wwPDB validaton report |
---|---|---|---|---|
Full document | 7k5j_full_validation.pdf.gz | 913.5 KB | Display | |
Data in XML | 7k5j_validation.xml.gz | 170.7 KB | Display | |
Data in CIF | 7k5j_validation.cif.gz | 261.8 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/k5/7k5j ftp://data.pdbj.org/pub/pdb/validation_reports/k5/7k5j | HTTPS FTP |
-Related structure data
Related structure data | 6nyaS S: Starting model for refinement |
---|---|
Similar structure data |
-Links
-Assembly
Deposited unit |
| |||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 |
| |||||||||||||||||||||||||||||||||
2 |
| |||||||||||||||||||||||||||||||||
3 |
| |||||||||||||||||||||||||||||||||
4 |
| |||||||||||||||||||||||||||||||||
5 |
| |||||||||||||||||||||||||||||||||
6 |
| |||||||||||||||||||||||||||||||||
7 |
| |||||||||||||||||||||||||||||||||
8 |
| |||||||||||||||||||||||||||||||||
Unit cell |
| |||||||||||||||||||||||||||||||||
Noncrystallographic symmetry (NCS) | NCS domain:
|