登録情報 | データベース: PDB / ID: 1nwq |
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タイトル | CRYSTAL STRUCTURE OF C/EBPALPHA-DNA COMPLEX |
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要素 | - 5'-D(*AP*AP*AP*CP*TP*GP*GP*AP*TP*TP*GP*CP*GP*CP*AP*AP*TP*AP*GP*GP*A)-3'
- 5'-D(*TP*TP*CP*CP*TP*AP*TP*TP*GP*CP*GP*CP*AP*AP*TP*CP*CP*AP*GP*TP*T)-3'
- CCAAT/enhancer binding protein alpha
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キーワード | TRANSCRIPTION/DNA / BASIC LEUCINE ZIPPER / PROTEIN-DNA COMPLEX / TRANSCRIPTION-DNA COMPLEX |
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機能・相同性 | 機能・相同性情報
Transcriptional regulation of granulopoiesis / response to vitamin B2 / CHOP-C/EBP complex / HMG box domain binding / Rb-E2F complex / response to phenylpropanoid / cellular response to xenobiotic stimulus => GO:0071466 / RNA polymerase I transcription regulatory region sequence-specific DNA binding / positive regulation of DNA-templated transcription initiation / granulocyte differentiation ...Transcriptional regulation of granulopoiesis / response to vitamin B2 / CHOP-C/EBP complex / HMG box domain binding / Rb-E2F complex / response to phenylpropanoid / cellular response to xenobiotic stimulus => GO:0071466 / RNA polymerase I transcription regulatory region sequence-specific DNA binding / positive regulation of DNA-templated transcription initiation / granulocyte differentiation / urea cycle / myeloid cell differentiation / positive regulation of macrophage activation / osteoblast development / positive regulation of transcription by RNA polymerase III / interleukin-6-mediated signaling pathway / cellular response to lithium ion / response to dexamethasone / fat cell differentiation / lipid homeostasis / transcription by RNA polymerase I / inner ear development / transcription factor binding / macrophage differentiation / cellular response to organic cyclic compound / negative regulation of cell cycle / white fat cell differentiation / embryonic placenta development / positive regulation of fat cell differentiation / animal organ regeneration / positive regulation of osteoblast differentiation / brown fat cell differentiation / cell maturation / Notch signaling pathway / cholesterol metabolic process / mitochondrion organization / response to nutrient / liver development / acute-phase response / lung development / memory / kinase binding / nuclear matrix / histone deacetylase binding / positive regulation of inflammatory response / RNA polymerase II transcription regulator complex / glucose homeostasis / cellular response to tumor necrosis factor / regulation of cell population proliferation / DNA-binding transcription activator activity, RNA polymerase II-specific / transcription regulator complex / sequence-specific DNA binding / cell differentiation / transcription cis-regulatory region binding / DNA-binding transcription factor activity, RNA polymerase II-specific / protein heterodimerization activity / RNA polymerase II cis-regulatory region sequence-specific DNA binding / DNA-binding transcription factor activity / protein domain specific binding / negative regulation of cell population proliferation / negative regulation of DNA-templated transcription / chromatin binding / positive regulation of gene expression / protein-containing complex binding / regulation of DNA-templated transcription / nucleolus / regulation of transcription by RNA polymerase II / positive regulation of DNA-templated transcription / negative regulation of transcription by RNA polymerase II / protein homodimerization activity / positive regulation of transcription by RNA polymerase II / protein-containing complex / DNA binding / identical protein binding / nucleus類似検索 - 分子機能 CCAAT/enhancer-binding protein, chordates / Basic region leucine zipper / Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #170 / Basic-leucine zipper (bZIP) domain profile. / basic region leucin zipper / Basic-leucine zipper domain / Single alpha-helices involved in coiled-coils or other helix-helix interfaces / Up-down Bundle / Mainly Alpha類似検索 - ドメイン・相同性 DNA / DNA (> 10) / CCAAT/enhancer-binding protein alpha類似検索 - 構成要素 |
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生物種 | ![](img/tx_mammal.gif) Rattus norvegicus (ドブネズミ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.8 Å |
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データ登録者 | Miller, M. / Shuman, J.D. / Sebastian, T. / Dauter, Z. / Johnson, P.F. |
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引用 | ジャーナル: J.Biol.Chem. / 年: 2003 タイトル: Structural Basis for DNA Recognition by the Basic Region Leucine Zipper Transcription Factor CCAAT/enhancer Binding Protein Alpha 著者: Miller, M. / Shuman, J.D. / Sebastian, T. / Dauter, Z. / Johnson, P.F. |
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履歴 | 登録 | 2003年2月6日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2003年5月13日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年4月29日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2023年8月16日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details |
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