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- EMDB-4735: Structure of XBP1u-paused ribosome nascent chain complex with SRP. -

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Basic information

Entry
Database: EMDB / ID: EMD-4735
TitleStructure of XBP1u-paused ribosome nascent chain complex with SRP.
Map dataStructure of XBP1u-paused nascent chain complex with SRP.
Sample
  • Complex: Structure of XBP1u-paused ribosome nascent chain complex with SRP.
    • Complex: Structure of XBP1u-paused nascent chain complex with SRP.
      • Protein or peptide: x 84 types
      • RNA: x 8 types
    • Complex: P- and E- site tRNA
    • Complex: X-box-binding protein 1
    • Complex: mRNA encoding XBP1u
    • Complex: SRP
    • Complex: Signal sequence (HR2)
  • Ligand: x 2 types
Keywordstranslational pausing / XBP1 / UPR / cotranslational targeting / SRP. / RIBOSOME
Function / homology
Function and homology information


epithelial cell maturation involved in salivary gland development / positive regulation of vascular wound healing / SRP-dependent cotranslational protein targeting to membrane / ATF6-mediated unfolded protein response / positive regulation of protein acetylation / SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition / endoplasmic reticulum signal peptide binding / response to insulin-like growth factor stimulus / signal recognition particle, endoplasmic reticulum targeting / glandular epithelial cell maturation ...epithelial cell maturation involved in salivary gland development / positive regulation of vascular wound healing / SRP-dependent cotranslational protein targeting to membrane / ATF6-mediated unfolded protein response / positive regulation of protein acetylation / SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition / endoplasmic reticulum signal peptide binding / response to insulin-like growth factor stimulus / signal recognition particle, endoplasmic reticulum targeting / glandular epithelial cell maturation / sterol homeostasis / positive regulation of lactation / IRE1alpha activates chaperones / ATF6 (ATF6-alpha) activates chaperone genes / positive regulation of plasma cell differentiation / positive regulation of phospholipid biosynthetic process / positive regulation of ERAD pathway / negative regulation of myotube differentiation / intracellular triglyceride homeostasis / signal recognition particle binding / protein targeting to ER / granulocyte differentiation / signal-recognition-particle GTPase / negative regulation of translational elongation / cellular response to fructose stimulus / cellular response to laminar fluid shear stress / SRP-dependent cotranslational protein targeting to membrane, translocation / XBP1(S) activates chaperone genes / cellular response to nutrient / 7S RNA binding / SRP-dependent cotranslational protein targeting to membrane / cellular response to fluid shear stress / positive regulation of MHC class II biosynthetic process / exocrine pancreas development / negative regulation of endoplasmic reticulum unfolded protein response / positive regulation of vascular associated smooth muscle cell migration / positive regulation of hepatocyte proliferation / endothelial cell proliferation / ribosomal subunit / positive regulation of T cell differentiation / cellular response to peptide hormone stimulus / positive regulation of B cell differentiation / positive regulation of immunoglobulin production / muscle organ development / IRE1-mediated unfolded protein response / negative regulation of SMAD protein signal transduction / ubiquitin ligase inhibitor activity / positive regulation of endothelial cell apoptotic process / intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress / positive regulation of signal transduction by p53 class mediator / cellular response to vascular endothelial growth factor stimulus / positive regulation of TOR signaling / positive regulation of fat cell differentiation / 90S preribosome / adipose tissue development / fatty acid homeostasis / vascular endothelial growth factor receptor signaling pathway / neuron development / phagocytic cup / ribonucleoprotein complex binding / negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway / endoplasmic reticulum unfolded protein response / cellular response to glucose starvation / cis-regulatory region sequence-specific DNA binding / ribosomal small subunit export from nucleus / positive regulation of vascular associated smooth muscle cell proliferation / rough endoplasmic reticulum / translation regulator activity / ERAD pathway / gastrulation / MDM2/MDM4 family protein binding / neutrophil chemotaxis / positive regulation of autophagy / cytosolic ribosome / class I DNA-(apurinic or apyrimidinic site) endonuclease activity / DNA-(apurinic or apyrimidinic site) lyase / cellular response to interleukin-4 / response to endoplasmic reticulum stress / cholesterol homeostasis / maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / cellular response to leukemia inhibitory factor / ribosomal large subunit biogenesis / positive regulation of apoptotic signaling pathway / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / nuclear estrogen receptor binding / maturation of SSU-rRNA / RNA polymerase II transcription regulatory region sequence-specific DNA binding / cellular response to amino acid stimulus / regulation of cell growth / small-subunit processome / cellular response to glucose stimulus / phosphatidylinositol 3-kinase/protein kinase B signal transduction / negative regulation of transforming growth factor beta receptor signaling pathway / chromatin DNA binding / liver development / protein destabilization / negative regulation of ERK1 and ERK2 cascade / regulation of protein stability / autophagy / positive regulation of interleukin-6 production
Similarity search - Function
: / Signal recognition particle, SRP9 subunit / SRP9 domain / Signal recognition particle SRP9 / Signal recognition particle 9 kDa protein (SRP9) / Signal recognition particle, SRP14 subunit / Signal recognition particle, SRP9/SRP14 subunit / Signal recognition particle 14kD protein / Signal recognition particle subunit SRP68 / Signal recognition particle subunit SRP68, RNA-binding domain ...: / Signal recognition particle, SRP9 subunit / SRP9 domain / Signal recognition particle SRP9 / Signal recognition particle 9 kDa protein (SRP9) / Signal recognition particle, SRP14 subunit / Signal recognition particle, SRP9/SRP14 subunit / Signal recognition particle 14kD protein / Signal recognition particle subunit SRP68 / Signal recognition particle subunit SRP68, RNA-binding domain / SRP68, N-terminal domain superfamily / RNA-binding signal recognition particle 68 / Signal recognition particle, SRP54 subunit, eukaryotic / Signal recognition particle, SRP19 subunit / Signal recognition particle, subunit SRP19-like superfamily / SRP19 protein / SRP/SRP receptor, N-terminal / Signal recognition particle, SRP54 subunit / Signal recognition particle, SRP54 subunit, M-domain / Signal recognition particle, SRP54 subunit, M-domain superfamily / Signal peptide binding domain / SRP54-type proteins GTP-binding domain signature. / Signal recognition particle SRP54, helical bundle / Signal recognition particle SRP54, N-terminal domain superfamily / SRP54-type protein, helical bundle domain / SRP54-type protein, helical bundle domain / Signal recognition particle, SRP54 subunit, GTPase domain / SRP54-type protein, GTPase domain / SRP54-type protein, GTPase domain / Basic region leucine zipper / Basic-leucine zipper (bZIP) domain signature. / Basic-leucine zipper (bZIP) domain profile. / basic region leucin zipper / Basic-leucine zipper domain / Basic-leucine zipper domain superfamily / 60S acidic ribosomal protein P0 / Ribosomal protein L6, N-terminal / Ribosomal protein L6, N-terminal domain / Ubiquitin-like protein FUBI / Ribosomal protein L30e / Ribosomal protein L28e / Ribosomal L15/L27a, N-terminal / Ribosomal protein L2, archaeal-type / Ribosomal protein L23 / Ribosomal protein L30e signature 1. / 60S ribosomal protein L10P, insertion domain / Insertion domain in 60S ribosomal protein L10P / Ribosomal L28e/Mak16 / Ribosomal L28e protein family / Ribosomal protein L30e signature 2. / Ribosomal protein L30e, conserved site / Ribosomal protein L30/YlxQ / metallochaperone-like domain / TRASH domain / Ribosomal protein L41 / Ribosomal protein L41 / : / Ribosomal protein S12e signature. / Ribosomal protein S12e / Ribosomal protein L29e / Ribosomal L29e protein family / Ribosomal protein S19e, conserved site / Ribosomal protein S19e signature. / Small (40S) ribosomal subunit Asc1/RACK1 / Ribosomal protein L27e, conserved site / Ribosomal protein L27e signature. / Ribosomal protein L10e, conserved site / Ribosomal protein L10e signature. / S27a-like superfamily / Ribosomal protein L10e / 40S Ribosomal protein S10 / : / Ribosomal protein L44e signature. / Ribosomal protein S7e signature. / Ribosomal protein L24e, conserved site / Ribosomal protein L24e signature. / Plectin/S10, N-terminal / Plectin/S10 domain / : / Ribosomal protein L6e signature. / Ribosomal protein S8e subdomain, eukaryotes / : / Ribosomal protein S17e, conserved site / Ribosomal protein S17e signature. / Ribosomal protein S25 / S25 ribosomal protein / Ribosomal protein L44e / Ribosomal protein S3Ae, conserved site / Ribosomal protein L44 / Ribosomal protein S3Ae signature. / Ribosomal protein S30 / Ribosomal protein S30 / Ribosomal protein S27a / Ribosomal protein L34e, conserved site / Ribosomal protein S27a / Ribosomal protein L34e signature. / Ribosomal protein S27a / Ribosomal protein L5 eukaryotic, C-terminal / Ribosomal L18 C-terminal region / Ribosomal protein 60S L18 and 50S L18e
Similarity search - Domain/homology
Small ribosomal subunit protein eS32 / Large ribosomal subunit protein uL16 / Small ribosomal subunit protein uS4 / Signal recognition particle 9 kDa protein / Large ribosomal subunit protein uL22 / Large ribosomal subunit protein eL24 / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL33 / Small ribosomal subunit protein eS12 / Large ribosomal subunit protein eL29 ...Small ribosomal subunit protein eS32 / Large ribosomal subunit protein uL16 / Small ribosomal subunit protein uS4 / Signal recognition particle 9 kDa protein / Large ribosomal subunit protein uL22 / Large ribosomal subunit protein eL24 / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL33 / Small ribosomal subunit protein eS12 / Large ribosomal subunit protein eL29 / Small ribosomal subunit protein uS9 / Large ribosomal subunit protein eL31 / Large ribosomal subunit protein eL21 / Large ribosomal subunit protein uL29 / Small ribosomal subunit protein RACK1 / Ubiquitin-ribosomal protein eS31 fusion protein / Large ribosomal subunit protein eL6 / Large ribosomal subunit protein uL11 / Large ribosomal subunit protein uL15 / Small ribosomal subunit protein uS15 / Large ribosomal subunit protein uL24 / Small ribosomal subunit protein eS1 / Large ribosomal subunit protein eL8 / Large ribosomal subunit protein uL30 / Small ribosomal subunit protein eS7 / Large ribosomal subunit protein uL4 / Large ribosomal subunit protein uL6 / Large ribosomal subunit protein eL43 / Large ribosomal subunit protein uL18 / Small ribosomal subunit protein uS12 / Small ribosomal subunit protein uS13 / Large ribosomal subunit protein eL42 / Large ribosomal subunit protein eL15 / Large ribosomal subunit protein uL14 / Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein / Small ribosomal subunit protein eS25 / Large ribosomal subunit protein eL30 / Small ribosomal subunit protein uS7 / Small ribosomal subunit protein uS8 / Small ribosomal subunit protein eS28 / Small ribosomal subunit protein eS8 / Small ribosomal subunit protein eS4 / Large ribosomal subunit protein uL3 / Small ribosomal subunit protein eS6 / Small ribosomal subunit protein eS19 / Small ribosomal subunit protein uS3 / Small ribosomal subunit protein uS13 / Uncharacterized protein / Small ribosomal subunit protein eS10 / Small ribosomal subunit protein uS17 / Large ribosomal subunit protein uL2 / Large ribosomal subunit protein eL39 / Large ribosomal subunit protein eL36 / Small ribosomal subunit protein eS17 / Large ribosomal subunit protein uL5 / Large ribosomal subunit protein eL32 / Large ribosomal subunit protein uL22 / Large ribosomal subunit protein uL6 / Large ribosomal subunit protein uL15/eL18 domain-containing protein / Large ribosomal subunit protein eL27 / Small ribosomal subunit protein eS27 / Small ribosomal subunit protein uS19 / 60S acidic ribosomal protein P0 / Large ribosomal subunit protein eL28 / Small ribosomal subunit protein uS14 / Large ribosomal subunit protein eL34 / Signal recognition particle 19 kDa protein / Signal recognition particle 14 kDa protein / X-box-binding protein 1 / Signal recognition particle subunit SRP54 / Signal recognition particle subunit SRP68 / Large ribosomal subunit protein eL14 / Large ribosomal subunit protein eL37
Similarity search - Component
Biological speciesOryctolagus cuniculus (rabbit) / Saccharomyces cerevisiae (brewer's yeast) / Homo sapiens (human) / Canis lupus familiaris (dog)
Methodsingle particle reconstruction / cryo EM / Resolution: 3.7 Å
AuthorsShanmuganathan V / Cheng J
Funding support Germany, 1 items
OrganizationGrant numberCountry
German Research FoundationGRK1721 Germany
CitationJournal: Elife / Year: 2019
Title: Structural and mutational analysis of the ribosome-arresting human XBP1u.
Authors: Vivekanandan Shanmuganathan / Nina Schiller / Anastasia Magoulopoulou / Jingdong Cheng / Katharina Braunger / Florian Cymer / Otto Berninghausen / Birgitta Beatrix / Kenji Kohno / Gunnar von ...Authors: Vivekanandan Shanmuganathan / Nina Schiller / Anastasia Magoulopoulou / Jingdong Cheng / Katharina Braunger / Florian Cymer / Otto Berninghausen / Birgitta Beatrix / Kenji Kohno / Gunnar von Heijne / Roland Beckmann /
Abstract: XBP1u, a central component of the unfolded protein response (UPR), is a mammalian protein containing a functionally critical translational arrest peptide (AP). Here, we present a 3 Å cryo-EM ...XBP1u, a central component of the unfolded protein response (UPR), is a mammalian protein containing a functionally critical translational arrest peptide (AP). Here, we present a 3 Å cryo-EM structure of the stalled human XBP1u AP. It forms a unique turn in the ribosomal exit tunnel proximal to the peptidyl transferase center where it causes a subtle distortion, thereby explaining the temporary translational arrest induced by XBP1u. During ribosomal pausing the hydrophobic region 2 (HR2) of XBP1u is recognized by SRP, but fails to efficiently gate the Sec61 translocon. An exhaustive mutagenesis scan of the XBP1u AP revealed that only 8 out of 20 mutagenized positions are optimal; in the remaining 12 positions, we identify 55 different mutations increase the level of translational arrest. Thus, the wildtype XBP1u AP induces only an intermediate level of translational arrest, allowing efficient targeting by SRP without activating the Sec61 channel.
History
DepositionMar 27, 2019-
Header (metadata) releaseJul 10, 2019-
Map releaseJul 10, 2019-
UpdateNov 13, 2024-
Current statusNov 13, 2024Processing site: PDBe / Status: Released

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Structure visualization

Movie
  • Surface view with section colored by density value
  • Surface level: 0.08
  • Imaged by UCSF Chimera
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  • Surface view colored by height
  • Surface level: 0.08
  • Imaged by UCSF Chimera
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  • Surface view with fitted model
  • Atomic models: PDB-6r6g
  • Surface level: 0.08
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Structure viewerEM map:
SurfViewMolmilJmol/JSmol
Supplemental images

emd_4735.png

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Map

FileDownload / File: emd_4735.map.gz / Format: CCP4 / Size: 236.9 MB / Type: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
AnnotationStructure of XBP1u-paused nascent chain complex with SRP.
Projections & slices

Image control

Size
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Others
AxesZ (Sec.)Y (Row.)X (Col.)
1.08 Å/pix.
x 396 pix.
= 429.264 Å		1.08 Å/pix.
x 396 pix.
= 429.264 Å		1.08 Å/pix.
x 396 pix.
= 429.264 Å

Surface

Projections

Slices (1/3)

Slices (1/2)

Slices (2/3)

Images are generated by Spider.

Voxel sizeX=Y=Z: 1.084 Å
Density

Histogram

Histogram (log scale)
Contour LevelBy AUTHOR: 0.08 / Movie #1: 0.08
Minimum - Maximum-0.45232785 - 0.6131792
Average (Standard dev.)0.001940717 (±0.025703479)
SymmetrySpace group: 1
Details

EMDB XML:

Map geometry
Axis orderXYZ
Origin000
Dimensions396396396
Spacing396396396
CellA=B=C: 429.264 Å
α=β=γ: 90.0 °

CCP4 map header:

modeImage stored as Reals
Å/pix. X/Y/Z1.0841.0841.084
M x/y/z396396396
origin x/y/z0.0000.0000.000
length x/y/z429.264429.264429.264
α/β/γ90.00090.00090.000
MAP C/R/S123
start NC/NR/NS000
NC/NR/NS396396396
D min/max/mean-0.4520.6130.002

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Supplemental data

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Additional map: Structure of XBP1u-paused nascent chain complex with SRP...

Fileemd_4735_additional.map
AnnotationStructure of XBP1u-paused nascent chain complex with SRP (lowpass filtered at 6 A)
Projections & Slices
AxesZYX

Projections

Slices (1/2)
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Sample components

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Entire : Structure of XBP1u-paused ribosome nascent chain complex with SRP.

EntireName: Structure of XBP1u-paused ribosome nascent chain complex with SRP.
Components
  • Complex: Structure of XBP1u-paused ribosome nascent chain complex with SRP.
    • Complex: Structure of XBP1u-paused nascent chain complex with SRP.
      • Protein or peptide: eS31
      • Protein or peptide: X-box-binding protein 1
      • RNA: P-tRNA
      • RNA: E-tRNA
      • RNA: mRNA
      • RNA: 28S ribosomal RNA
      • Protein or peptide: ribosomal protein RACK1
      • RNA: 5S ribosomal RNA
      • RNA: 5.8S ribosomal RNA
      • Protein or peptide: uS14
      • Protein or peptide: uL2
      • Protein or peptide: 40S ribosomal protein S30
      • Protein or peptide: uL3
      • Protein or peptide: 40S ribosomal protein S7
      • Protein or peptide: uL4
      • Protein or peptide: 40S ribosomal protein S8
      • Protein or peptide: Ribosomal protein S9 (Predicted)
      • Protein or peptide: 60S ribosomal protein L5
      • Protein or peptide: Ribosomal protein S11
      • Protein or peptide: 60S ribosomal protein L6
      • Protein or peptide: Ribosomal protein S28
      • Protein or peptide: uL30
      • Protein or peptide: Ribosomal protein S20
      • Protein or peptide: eL8
      • Protein or peptide: uL6
      • Protein or peptide: 40S ribosomal protein S21
      • Protein or peptide: Ribosomal protein L10 (Predicted)
      • Protein or peptide: uS13
      • Protein or peptide: 40S ribosomal protein S27
      • Protein or peptide: Ribosomal protein L11
      • RNA: 18S ribosomal RNA
      • Protein or peptide: eS17
      • Protein or peptide: 60S ribosomal protein L13
      • Protein or peptide: 40S ribosomal protein S26
      • Protein or peptide: Ribosomal protein L14
      • Protein or peptide: 40S ribosomal protein S14
      • Protein or peptide: Ribosomal protein L15
      • Protein or peptide: 40S ribosomal protein S24
      • Protein or peptide: 60S ribosomal protein L13a
      • Protein or peptide: ribosomal protein eS25
      • Protein or peptide: uL22
      • Protein or peptide: eS19
      • Protein or peptide: eL18
      • Protein or peptide: ribosomal protein uS15
      • Protein or peptide: 60S ribosomal protein L19
      • Protein or peptide: 40S ribosomal protein S12
      • Protein or peptide: eL20
      • Protein or peptide: eS10
      • Protein or peptide: eL21
      • Protein or peptide: Ribosomal protein S15a
      • Protein or peptide: Ribosomal protein S16
      • Protein or peptide: 60S ribosomal protein L22
      • Protein or peptide: Ribosomal protein S23
      • Protein or peptide: eL14
      • Protein or peptide: Ribosomal protein L24
      • Protein or peptide: uS19
      • Protein or peptide: uL23
      • Protein or peptide: Ribosomal protein L26
      • Protein or peptide: 60S ribosomal protein L27
      • Protein or peptide: uL15
      • Protein or peptide: eL29
      • Protein or peptide: eL30
      • Protein or peptide: eL31
      • Protein or peptide: eL32
      • Protein or peptide: eL33
      • Protein or peptide: eL34
      • Protein or peptide: uL29
      • Protein or peptide: 60S ribosomal protein L36
      • Protein or peptide: Ribosomal protein L37
      • Protein or peptide: 60S ribosomal protein L38
      • Protein or peptide: eL39
      • Protein or peptide: 60S ribosomal protein L40
      • Protein or peptide: 60s ribosomal protein l41
      • Protein or peptide: eL42
      • Protein or peptide: ribosomal protein eL43
      • Protein or peptide: uS2
      • Protein or peptide: eL28
      • Protein or peptide: 60S acidic ribosomal protein P0
      • Protein or peptide: uL11
      • Protein or peptide: 40S ribosomal protein S3a
      • Protein or peptide: uS5
      • Protein or peptide: Ribosomal protein S3
      • Protein or peptide: 40S ribosomal protein S4
      • Protein or peptide: Ribosomal protein S5
      • Protein or peptide: 40S ribosomal protein S6
      • Protein or peptide: Signal recognition particle 54 kDa protein
      • RNA: 7S RNA
      • Protein or peptide: Signal recognition particle subunit SRP19
      • Protein or peptide: Signal recognition particle subunit SRP68
      • Protein or peptide: Signal recognition particle 9 kDa protein
      • Protein or peptide: Signal recognition particle 14 kDa protein
      • Protein or peptide: Signal sequence (HR2)
    • Complex: P- and E- site tRNA
    • Complex: X-box-binding protein 1
    • Complex: mRNA encoding XBP1u
    • Complex: SRP
    • Complex: Signal sequence (HR2)
  • Ligand: MAGNESIUM ION
  • Ligand: ZINC ION

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Supramolecule #1: Structure of XBP1u-paused ribosome nascent chain complex with SRP.

SupramoleculeName: Structure of XBP1u-paused ribosome nascent chain complex with SRP.
type: complex / ID: 1 / Parent: 0 / Macromolecule list: #1-#92

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Supramolecule #2: Structure of XBP1u-paused nascent chain complex with SRP.

SupramoleculeName: Structure of XBP1u-paused nascent chain complex with SRP.
type: complex / ID: 2 / Parent: 1 / Macromolecule list: #1-#92 / Details: ribosome
Source (natural)Organism: Oryctolagus cuniculus (rabbit)

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Supramolecule #3: P- and E- site tRNA

SupramoleculeName: P- and E- site tRNA / type: complex / ID: 3 / Parent: 1 / Macromolecule list: #3-#4
Source (natural)Organism: Saccharomyces cerevisiae (brewer's yeast)

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Supramolecule #4: X-box-binding protein 1

SupramoleculeName: X-box-binding protein 1 / type: complex / ID: 4 / Parent: 1 / Macromolecule list: #2 / Details: Pausing sequence of XBP1u
Source (natural)Organism: Homo sapiens (human)

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Supramolecule #5: mRNA encoding XBP1u

SupramoleculeName: mRNA encoding XBP1u / type: complex / ID: 5 / Parent: 1 / Macromolecule list: #5
Source (natural)Organism: Homo sapiens (human)

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Supramolecule #6: SRP

SupramoleculeName: SRP / type: complex / ID: 6 / Parent: 1 / Macromolecule list: #86-#91
Source (natural)Organism: Canis lupus familiaris (dog)

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Supramolecule #7: Signal sequence (HR2)

SupramoleculeName: Signal sequence (HR2) / type: complex / ID: 7 / Parent: 1 / Macromolecule list: #92
Source (natural)Organism: Homo sapiens (human)

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Macromolecule #1: eS31

MacromoleculeName: eS31 / type: protein_or_peptide / ID: 1 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 7.98644 KDa
SequenceString:
KSYTTPKKNK HKRKKVKLAV LKYYKVDENG KISRLRRECP SDECGAGVFM ASHFDRHYCG KCCLTYCF

UniProtKB: Ubiquitin-ribosomal protein eS31 fusion protein

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Macromolecule #2: X-box-binding protein 1

MacromoleculeName: X-box-binding protein 1 / type: protein_or_peptide / ID: 2 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Homo sapiens (human)
Molecular weightTheoretical: 2.89538 KDa
Recombinant expressionOrganism: Oryctolagus cuniculus (rabbit)
SequenceString:
DPVPYQPPFL CQWGRHQPAW KPLM

UniProtKB: X-box-binding protein 1

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Macromolecule #7: ribosomal protein RACK1

MacromoleculeName: ribosomal protein RACK1 / type: protein_or_peptide / ID: 7 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 34.669113 KDa
SequenceString: TEQMTLRGTL KGHNGWVTQI ATTPQFPDMI LSASRDKTII MWKLTRDETN YGIPQRALRG HSHFVSDVVI SSDGQFALSG SWDGTLRLW DLTTGTTTRR FVGHTKDVLS VAFSSDNRQI VSGSRDKTIK LWNTLGVCKY TVQDESHSEW VSCVRFSPNS S NPIIVSCG ...String:
TEQMTLRGTL KGHNGWVTQI ATTPQFPDMI LSASRDKTII MWKLTRDETN YGIPQRALRG HSHFVSDVVI SSDGQFALSG SWDGTLRLW DLTTGTTTRR FVGHTKDVLS VAFSSDNRQI VSGSRDKTIK LWNTLGVCKY TVQDESHSEW VSCVRFSPNS S NPIIVSCG WDKLVKVWNL ANCKLKTNHI GHTGYLNTVT VSPDGSLCAS GGKDGQAMLW DLNEGKHLYT LDGGDIINAL CF SPNRYWL CAATGPSIKI WDLEGKIIVD ELKQEVISTS SKAEPPQCTS LAWSADGQTL FAGYTDNLVR VWQVTI

UniProtKB: Small ribosomal subunit protein RACK1

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Macromolecule #10: uS14

MacromoleculeName: uS14 / type: protein_or_peptide / ID: 10 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 6.559625 KDa
SequenceString:
GHQQLYWSHP RKFGQGSRSC RVCSNRHGLI RKYGLNMCRQ CFRQYAKDIG FIKLD

UniProtKB: Small ribosomal subunit protein uS14

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Macromolecule #11: uL2

MacromoleculeName: uL2 / type: protein_or_peptide / ID: 11 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 26.998613 KDa
SequenceString: GRVIRGQRKG AGSVFRAHVK HRKGAARLRA VDFAERHGYI KGIVKDIIHD PGRGAPLAKV VFRDPYRFKK RTELFIAAEG IHTGQFVYC GKKAQLNIGN VLPVGTMPEG TIVCCLEEKP GDRGKLARAS GNYATVISHN PETKKTRVKL PSGSKKVISS A NRAVVGVV ...String:
GRVIRGQRKG AGSVFRAHVK HRKGAARLRA VDFAERHGYI KGIVKDIIHD PGRGAPLAKV VFRDPYRFKK RTELFIAAEG IHTGQFVYC GKKAQLNIGN VLPVGTMPEG TIVCCLEEKP GDRGKLARAS GNYATVISHN PETKKTRVKL PSGSKKVISS A NRAVVGVV AGGGRIDKPI LKAGRAYHKY KAKRNCWPRV RGVAMNPVEH PFGGGNHQHI GKPSTIRRDA PAGRKVGLIA AR RTGRLRG T

UniProtKB: Large ribosomal subunit protein uL2

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Macromolecule #12: 40S ribosomal protein S30

MacromoleculeName: 40S ribosomal protein S30 / type: protein_or_peptide / ID: 12 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 6.317539 KDa
SequenceString:
SLARVGKVRG QTLKVAKQEK KKKRTGRAKR RMQYNRRFVN VVPTFGKKKG PNANS

UniProtKB: Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein

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Macromolecule #13: uL3

MacromoleculeName: uL3 / type: protein_or_peptide / ID: 13 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 45.119812 KDa
SequenceString: SHRKFSAPRH GSLGFLPRKR SSRHRGKVKS FPKDDPSKPV HLTAFLGYKA GMTHIVREVD RPGSKVNKKE VVEAVTIVET PPMVVVGIV GYVETPRGLR TFKTVFAEHI SDECKRRFYK NWHKSKKKAF TKYCKKWQDD AGKRQLDKDF SSMKKYCQVI R VLAHTQMR ...String:
SHRKFSAPRH GSLGFLPRKR SSRHRGKVKS FPKDDPSKPV HLTAFLGYKA GMTHIVREVD RPGSKVNKKE VVEAVTIVET PPMVVVGIV GYVETPRGLR TFKTVFAEHI SDECKRRFYK NWHKSKKKAF TKYCKKWQDD AGKRQLDKDF SSMKKYCQVI R VLAHTQMR LLPLRQKKAH LMEIQVNGGT VAEKLDWARE RLEQQVPVSQ VFGQDEMIDV IGVTKGKGYK GVTSRWHTKK LP RKTHRGL RKVACIGAWH PARVAFSVAR AGQKGYHHRT EINKKIYKIG QGYLIKDGKL IKNNASTDYD LSDKSINPLG GFV HYGEVT NDFVMLKGCV VGTKKRVLTL RKSLLVQTKR RALEKIDLKF IDTTSKFGHG RFQTVEEKKA FMGPLKKD

UniProtKB: Large ribosomal subunit protein uL3

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Macromolecule #14: 40S ribosomal protein S7

MacromoleculeName: 40S ribosomal protein S7 / type: protein_or_peptide / ID: 14 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 21.629309 KDa
SequenceString:
AKIVKPNGEK PDEFESGISQ ALLELEMNSD LKAQLRELNI TAAKEIEVGG GRKAIIIFVP VPQLKSFQKI QVRLVRELEK KFSGKHVVF IAQRRILPKP TRKSRTKNKQ KRPRSRTLTA VHDAILEDLV FPSEIVGKRI RVKLDGSRLI KVHLDKAQQN N VEHKVETF SGVYKKLTGK DVNFEFPEFQ L

UniProtKB: Small ribosomal subunit protein eS7

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Macromolecule #15: uL4

MacromoleculeName: uL4 / type: protein_or_peptide / ID: 15 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 41.101414 KDa
SequenceString: ACARPLISVY SEKGESSGKN VTLPAVFKAP IRPDIVNFVH TNLRKNNRQP YAVSELAGHQ TSAESWGTGR AVARIPRVRG GGTHRSGQG AFGNMCRGGR MFAPTKTWRR WHRRVNTTQK RYAICSALAA SALPALVMSK GHRIEEVPEL PLVVEDKVEG Y KKTKEAVL ...String:
ACARPLISVY SEKGESSGKN VTLPAVFKAP IRPDIVNFVH TNLRKNNRQP YAVSELAGHQ TSAESWGTGR AVARIPRVRG GGTHRSGQG AFGNMCRGGR MFAPTKTWRR WHRRVNTTQK RYAICSALAA SALPALVMSK GHRIEEVPEL PLVVEDKVEG Y KKTKEAVL LLKKLKAWND IKKVYASQRM RAGKGKMRNR RRIQRRGPCV IYNEDNGIVK AFRNIPGITL LNVTKLNILK LA PGGHVGR FCIWTESAFR KLDDLYGTWR KAASLKSNYN LPMHKMLNTD LSRILKSPEI QRALRAPRKK IHRRVLKKNP LKN LRIMLK LNPYAKTMRR NTILRQARNH KLRVERAAAA LAAKSD

UniProtKB: Large ribosomal subunit protein uL4

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Macromolecule #16: 40S ribosomal protein S8

MacromoleculeName: 40S ribosomal protein S8 / type: protein_or_peptide / ID: 16 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 24.003012 KDa
SequenceString: GISRDNWHKR RKTGGKRKPY HKKRKYELGR PAANTKIGPR RIHTVRVRGG NKKYRALRLD VGNFSWGSEC CTRKTRIIDV VYNASNNEL VRTKTLVKNC IVLIDSTPYR QWYESHYALP LGRKKGAKLT PEEEEILNKK RSKKIQKKYD ERKKNAKISS L LEEQFQQG ...String:
GISRDNWHKR RKTGGKRKPY HKKRKYELGR PAANTKIGPR RIHTVRVRGG NKKYRALRLD VGNFSWGSEC CTRKTRIIDV VYNASNNEL VRTKTLVKNC IVLIDSTPYR QWYESHYALP LGRKKGAKLT PEEEEILNKK RSKKIQKKYD ERKKNAKISS L LEEQFQQG KLLACIASRP GQCGRADGYV LEGKELEFYL RKIKARKG

UniProtKB: Small ribosomal subunit protein eS8

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Macromolecule #17: Ribosomal protein S9 (Predicted)

MacromoleculeName: Ribosomal protein S9 (Predicted) / type: protein_or_peptide / ID: 17 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 21.649633 KDa
SequenceString:
PVARSWVCRK TYVTPRRPFE KSRLDQELKL IGEYGLRNKR EVWRVKFTLA KIRKAARELL TLDEKDPRRL FEGNALLRRL VRIGVLDEG KMKLDYILGL KIEDFLERRL QTQVFKLGLA KSIHHARVLI RQRHIRVRKQ VVNIPSFIVR LDSQKHIDFS L RSPYGGGR PGRVKRKNAK KGQGGAG

UniProtKB: Small ribosomal subunit protein uS4

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Macromolecule #18: 60S ribosomal protein L5

MacromoleculeName: 60S ribosomal protein L5 / type: protein_or_peptide / ID: 18 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 34.077391 KDa
SequenceString: FVKVVKNKAY FKRYQVKFRR RREGKTDYYA RKRLVIQDKN KYNTPKYRMI VRVTNRDIIC QIAYARIEGD MIVCAAYAHE LPKYGVKVG LTNYAAAYCT GLLLARRLLN RFGMDKIYEG QVEVTGDEYN VESIDGQPGA FTCYLDAGLA RTTTGNKVFG A LKGAVDGG ...String:
FVKVVKNKAY FKRYQVKFRR RREGKTDYYA RKRLVIQDKN KYNTPKYRMI VRVTNRDIIC QIAYARIEGD MIVCAAYAHE LPKYGVKVG LTNYAAAYCT GLLLARRLLN RFGMDKIYEG QVEVTGDEYN VESIDGQPGA FTCYLDAGLA RTTTGNKVFG A LKGAVDGG LSIPHSTKRF PGYDSESKEF NAEVHRKHIM GQNVADYMRY LMEEDEDAYK KQFSQYIKNN VTPDMMEEMY KK AHAAIRE NPVYEKKPKR EVKKKRWNRP KMSLAQKKDR VAQKKASFLR AQERAA

UniProtKB: Large ribosomal subunit protein uL18

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Macromolecule #19: Ribosomal protein S11

MacromoleculeName: Ribosomal protein S11 / type: protein_or_peptide / ID: 19 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 17.586766 KDa
SequenceString:
DIQTERAYQK QPTIFQNKKR VLLGETGKEK LPRYYKNIGL GFKTPKEAIE GTYIDKKCPF TGNVSIRGRI LSGVVTKMKM QRTIVIRRD YLHYIRKYNR FEKRHKNMSV HLSPCFRDVQ IGDIVTVGEC RPLSKTVRFN VLKVTKAAGT KK

UniProtKB: Small ribosomal subunit protein uS17

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Macromolecule #20: 60S ribosomal protein L6

MacromoleculeName: 60S ribosomal protein L6 / type: protein_or_peptide / ID: 20 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 28.818293 KDa
SequenceString: KGKPHCSRNP VLVRGIGRYS RSAMYSRKAL YKRKYAAPKS RIERKKKREK VLATVTKPVG GDKNGGTRVV KLRKMPRYYP TEDVPRKLL SHGKKPFSQH VRKLRASITP GTILIILTGR HRGKRVVFLK QLSSGLLLVT GPLSLNRVPL RRTHQKFVIA T STKIDISG ...String:
KGKPHCSRNP VLVRGIGRYS RSAMYSRKAL YKRKYAAPKS RIERKKKREK VLATVTKPVG GDKNGGTRVV KLRKMPRYYP TEDVPRKLL SHGKKPFSQH VRKLRASITP GTILIILTGR HRGKRVVFLK QLSSGLLLVT GPLSLNRVPL RRTHQKFVIA T STKIDISG VKIPKHLTDA YFKKKKLRKP RHQEGEIFDT EKEKYEITEQ RKVDQKAVDS QILPKIKAVP QLQGYLRSVF AL TNGVYPH KLVF

UniProtKB: Large ribosomal subunit protein eL6

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Macromolecule #21: Ribosomal protein S28

MacromoleculeName: Ribosomal protein S28 / type: protein_or_peptide / ID: 21 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 7.007069 KDa
SequenceString:
QPIKLARVTK VLGRTGSQGQ CTQVRVEFMD DTSRSIIRNV KGPVREGDVL TLLESEREAR RL

UniProtKB: Small ribosomal subunit protein eS28

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Macromolecule #22: uL30

MacromoleculeName: uL30 / type: protein_or_peptide / ID: 22 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 26.658754 KDa
SequenceString: NFAELKIKRL RKKFAQKMLR KARRKLIYEK AKHYHKEYRQ MYRTEIRMAR MARKAGNFYV PAEPKLAFVI RIRGINGVSP KVRKVLQLL RLRQIFNGTF VKLNKASINM LRIVEPYIAW GYPNLKSVNE LIYKRGYGKI NKKRIALTDN TLIARSLGKY N IICMEDLI ...String:
NFAELKIKRL RKKFAQKMLR KARRKLIYEK AKHYHKEYRQ MYRTEIRMAR MARKAGNFYV PAEPKLAFVI RIRGINGVSP KVRKVLQLL RLRQIFNGTF VKLNKASINM LRIVEPYIAW GYPNLKSVNE LIYKRGYGKI NKKRIALTDN TLIARSLGKY N IICMEDLI HEIYTVGKHF KEANNFLWPF KLSSPRGGMK KKTTHFVEGG DAGNREDQIN RLIRRMN

UniProtKB: Large ribosomal subunit protein uL30

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Macromolecule #23: Ribosomal protein S20

MacromoleculeName: Ribosomal protein S20 / type: protein_or_peptide / ID: 23 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 11.395489 KDa
SequenceString:
HRIRITLTSR NVKSLEKVCA DLIRGAKEKN LKVKGPVRMP TKTLRITTRK TPCGEGSKTW DRFQMRIHKR LIDLHSPSEI VKQITSISI EPGVEVEVTI A

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Macromolecule #24: eL8

MacromoleculeName: eL8 / type: protein_or_peptide / ID: 24 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 27.351377 KDa
SequenceString: VVNPLFEKRP KNFGIGQDIQ PKRDLTRFVK WPRYIRLQRQ RAILYKRLKV PPAINQFTQV LDRQTATQLL KLAHKYRPET KQEKKQRLL ARAEKKAAGK GDVPTKRPPV LRAGVNTVTT LVENKKAQLV VIAHDVDPIE LVVFLPALCR KMGVPYCILK G KARLGRLV ...String:
VVNPLFEKRP KNFGIGQDIQ PKRDLTRFVK WPRYIRLQRQ RAILYKRLKV PPAINQFTQV LDRQTATQLL KLAHKYRPET KQEKKQRLL ARAEKKAAGK GDVPTKRPPV LRAGVNTVTT LVENKKAQLV VIAHDVDPIE LVVFLPALCR KMGVPYCILK G KARLGRLV HRKTCTTVAF TQVNSEDKGA LAKLVEAIRT NYNDRYDEIR RHWGGNVLGP KSVARIAKLE KAKAKELATK LG

UniProtKB: Large ribosomal subunit protein eL8

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Macromolecule #25: uL6

MacromoleculeName: uL6 / type: protein_or_peptide / ID: 25 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 21.627215 KDa
SequenceString:
MKTILSNQTV DIPENVDISL KGRTVIVKGP RGTLRRDFNH INVELSLLGK KKKRLRVDKW WGNRKELATV RTICSHVQNM IKGVTLGFR YKMRSVYAHF PINVVIQENG SLVEIRNFLG EKYIRRVRMR PGVACSVSQA QKDELVLEGN DIELVSNSAA L IQQATTVK NKDIRKFLDG IYVSEKGTVQ QA

UniProtKB: Large ribosomal subunit protein uL6

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Macromolecule #26: 40S ribosomal protein S21

MacromoleculeName: 40S ribosomal protein S21 / type: protein_or_peptide / ID: 26 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 9.124389 KDa
SequenceString:
MQNDAGEFVD LYVPRKCSAS NRIIGAKDHA SIQMNVAEVD KVTGRFNGQF KTYAICGAIR RMGESDDSIL RLAKADGIVS KNF

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Macromolecule #27: Ribosomal protein L10 (Predicted)

MacromoleculeName: Ribosomal protein L10 (Predicted) / type: protein_or_peptide / ID: 27 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 24.511861 KDa
SequenceString: GRRPARCYRY CKNKPYPKSR FCRGVPDAKI RIFDLGRKKA KVDEFPLCGH MVSDEYEQLS SEALEAARIC ANKYMVKSCG KDGFHIRVR LHPFHVIRIN KMLSCAGADR LQTGMRGAFG KPQGTVARVH IGQVIMSIRT KLQNKEHVVE ALRRAKFKFP G RQKIHISK ...String:
GRRPARCYRY CKNKPYPKSR FCRGVPDAKI RIFDLGRKKA KVDEFPLCGH MVSDEYEQLS SEALEAARIC ANKYMVKSCG KDGFHIRVR LHPFHVIRIN KMLSCAGADR LQTGMRGAFG KPQGTVARVH IGQVIMSIRT KLQNKEHVVE ALRRAKFKFP G RQKIHISK KWGFTKFNAD EFEDMVAEKR LIPDGCGVKY IPNRGPLDKW RALHS

UniProtKB: Large ribosomal subunit protein uL16

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Macromolecule #28: uS13

MacromoleculeName: uS13 / type: protein_or_peptide / ID: 28 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 16.898648 KDa
SequenceString:
SLVIPEKFQH ILRVLNTNID GRRKIAFAIT AIKGVGRRYA HVVLRKADID LTKRAGELTE DEVERVITIM QNPRQYKIPD WFLNRQKDV KDGKYSQVLA NGLDNKLRED LERLKKIRAH RGLRHFWGLR VRGQHTKTTG RRGRT

UniProtKB: Small ribosomal subunit protein uS13

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Macromolecule #29: 40S ribosomal protein S27

MacromoleculeName: 40S ribosomal protein S27 / type: protein_or_peptide / ID: 29 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 9.34899 KDa
SequenceString:
PLAKDLLHPS PEEEKRKHKK KRLVQSPNSY FMDVKCPGCY KITTVFSHAQ TVVLCVGCST VLCQPTGGKA RLTEGCSFRR KQH

UniProtKB: Small ribosomal subunit protein eS27

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Macromolecule #30: Ribosomal protein L11

MacromoleculeName: Ribosomal protein L11 / type: protein_or_peptide / ID: 30 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 19.399498 KDa
SequenceString:
KENPMRELRI RKLCLNICVG ESGDRLTRAA KVLEQLTGQT PVFSKARYTV RSFGIRRNEK IAVHCTVRGA KAEEILEKGL KVREYELRK NNFSDTGNFG FGIQEHIDLG IKYDPSIGIY GLDFYVVLGR PGFSIADKKR RTGCIGAKHR ISKEEAMRWF Q QKYDGIIL PG

UniProtKB: Large ribosomal subunit protein uL5

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Macromolecule #32: eS17

MacromoleculeName: eS17 / type: protein_or_peptide / ID: 32 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 15.250714 KDa
SequenceString:
GRVRTKTVKK AARVIIEKYY TRLGNDFHTN KRVCEEIAII PSKKLRNKIA GYVTHLMKRI QRGPVRGISI KLQEEERERR DNYVPEVSA LDQEIIEVDP DTKEMLKLLD FGSLSNLQVT QPTVGMNFKT PRG

UniProtKB: Small ribosomal subunit protein eS17

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Macromolecule #33: 60S ribosomal protein L13

MacromoleculeName: 60S ribosomal protein L13 / type: protein_or_peptide / ID: 33 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 24.200525 KDa
SequenceString: APSRNGMILK PHFHKDWQRR VATWFNQPAR KIRRRKARQA RARRIAPRPA AGPIRPIVRC PTVRYHTKVR AGRGFSLEEL RVAGIHKKV ARTIGISVDP RRRNKSTESL QANVQRLKEY RSKLVLFPRK PSAPKKGDSS AEELKLATQL TGPVMPIRNV F KKEKARVI ...String:
APSRNGMILK PHFHKDWQRR VATWFNQPAR KIRRRKARQA RARRIAPRPA AGPIRPIVRC PTVRYHTKVR AGRGFSLEEL RVAGIHKKV ARTIGISVDP RRRNKSTESL QANVQRLKEY RSKLVLFPRK PSAPKKGDSS AEELKLATQL TGPVMPIRNV F KKEKARVI TEEEKNFKAF ASLRMARANA RLFGIRAKRA KEAAEQDVEK KK

UniProtKB: Uncharacterized protein

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Macromolecule #34: 40S ribosomal protein S26

MacromoleculeName: 40S ribosomal protein S26 / type: protein_or_peptide / ID: 34 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 11.645794 KDa
SequenceString:
TKKRRNNGRA KKGRGHVQPI RCTNCARCVP KDKAIKKFVI RNIVEAAAVR DISEASVFDA YVLPKLYVKL HYCVSCAIHS KVVRNRSRE ARKDRTPPPR FR

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Macromolecule #35: Ribosomal protein L14

MacromoleculeName: Ribosomal protein L14 / type: protein_or_peptide / ID: 35 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 16.217355 KDa
SequenceString:
VFRRFVEVGR VAYVSFGPHA GKLVAIVDVI DQNRALVDGP CTRVRRQAMP FKCMQLTDFI LKFPHSARQK YVRKAWEKAD INTKWAATR WAKKIEARER KAKMTDFDRY KVMKAKKMRN RIIKNEVKKL QRAALLKAS

UniProtKB: Large ribosomal subunit protein eL14

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Macromolecule #36: 40S ribosomal protein S14

MacromoleculeName: 40S ribosomal protein S14 / type: protein_or_peptide / ID: 36 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 14.544659 KDa
SequenceString:
SLGPQVAEGE NVFGVCHIFA SFNDTFVHVT DLSGKETICR VTGGMKVKAD RDESSPYAAM LAAQDVAQRC KELGITALHI KLRATGGNR TKTPGPGAQS ALRALARSGM KIGRIEDVTP IPSDSTRRKG GRRGRRL

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Macromolecule #37: Ribosomal protein L15

MacromoleculeName: Ribosomal protein L15 / type: protein_or_peptide / ID: 37 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 24.076088 KDa
SequenceString: GAYKYIQELW RKKQSDVMRF LLRVRCWQYR QLSALHRAPR PTRPDKARRL GYKAKQGYVI YRIRVRRGGR KRPVPKGATY GKPVHHGVN QLKFARSLQS VAEERAGRHC GALRVLNSYW VGEDSTYKFF EVILIDPFHK AIRRNPDTQW ITKPVHKHRE M RGLTSAGR ...String:
GAYKYIQELW RKKQSDVMRF LLRVRCWQYR QLSALHRAPR PTRPDKARRL GYKAKQGYVI YRIRVRRGGR KRPVPKGATY GKPVHHGVN QLKFARSLQS VAEERAGRHC GALRVLNSYW VGEDSTYKFF EVILIDPFHK AIRRNPDTQW ITKPVHKHRE M RGLTSAGR KSRGLGKGHK FHHTIGGSRR AAWRRRNTLQ LHRYR

UniProtKB: Large ribosomal subunit protein eL15

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Macromolecule #38: 40S ribosomal protein S24

MacromoleculeName: 40S ribosomal protein S24 / type: protein_or_peptide / ID: 38 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 14.432125 KDa
SequenceString:
TVTIRTRKFM TNRLLQRKQM VIDVLHPGKA TVPKTEIREK LAKMYKTTPD VIFVFGFRTH FGGGKTTGFG MIYDSLDYAK KNEPKHRLA RHGLYEKKKT SRKQRKERKN RMKKVRGTAK ANVGA

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Macromolecule #39: 60S ribosomal protein L13a

MacromoleculeName: 60S ribosomal protein L13a / type: protein_or_peptide / ID: 39 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 23.144859 KDa
SequenceString: QVLVLDGRGH LLGRLAAIVA KQVLLGRKVV VVRCEGINIS GNFYRNKLKY LAFLRKRMNT NPSRGPYHFR APSRIFWRTV RGMLPHKTK RGQAALDRLK VFDGIPPPYD KKKRMVVPAA LKVVRLKPTR KFAYLGRLAH EVGWKYQAVT ATLEEKRKEK A KIHYRKKK ...String:
QVLVLDGRGH LLGRLAAIVA KQVLLGRKVV VVRCEGINIS GNFYRNKLKY LAFLRKRMNT NPSRGPYHFR APSRIFWRTV RGMLPHKTK RGQAALDRLK VFDGIPPPYD KKKRMVVPAA LKVVRLKPTR KFAYLGRLAH EVGWKYQAVT ATLEEKRKEK A KIHYRKKK QLMRLRKQAE KNVEKKISKF TDVLKTHGLL V

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Macromolecule #40: ribosomal protein eS25

MacromoleculeName: ribosomal protein eS25 / type: protein_or_peptide / ID: 40 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 8.526119 KDa
SequenceString:
RDKLNNLVLF DKATYDKLCK EVPNYKLITP AVVSERLKIR GSLARAALQE LLSKGLIKLV SKHRAQVIYT RNTKG

UniProtKB: Small ribosomal subunit protein eS25

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Macromolecule #41: uL22

MacromoleculeName: uL22 / type: protein_or_peptide / ID: 41 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 17.758678 KDa
SequenceString:
VRYSLDPENP TKSCKSRGSN LRVHFKNTRE TAQAIKGMHI RKATKYLKDV TLKKQCVPFR RYNGGVGRCA QAKQWGWTQG RWPKKSAEF LLHMLKNAES NAELKGLDVD SLVIEHIQVN KAPKMRRRTY RAHGRINPYM SSPCHIEMIL TEKE

UniProtKB: Large ribosomal subunit protein uL22

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Macromolecule #42: eS19

MacromoleculeName: eS19 / type: protein_or_peptide / ID: 42 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 15.611003 KDa
SequenceString:
GVTVKDVNQQ EFVRALAAFL KKSGKLKVPE WVDTVKLAKH KELAPYDENW FYTRAASTAR HLYLRGGAGV GSMTKIYGGR QRNGVMPSH FSRGSKSVAR RVLQALEGLK MVEKDQDGGR KLTPQGQRDL DRIAGQVAAA KK

UniProtKB: Small ribosomal subunit protein eS19

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Macromolecule #43: eL18

MacromoleculeName: eL18 / type: protein_or_peptide / ID: 43 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 21.568492 KDa
SequenceString:
GVDIRHNKDR KVRRKEPKSQ DIYLRLLVKL YRFLARRTNS TFNQVVLKRL FMSRTNRPPL SLSRMIRKMK LPGRENKTAV VVGTVTDDV RVQEVPKLKV CALRVTSRAR SRILKAGGKI LTFDQLALDS PKGRGTVLLS GPRKGREVYR HFGKAPGTPH S HTKPYVRS KGRKFERARG RRASRGYKN

UniProtKB: Large ribosomal subunit protein uL15/eL18 domain-containing protein

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Macromolecule #44: ribosomal protein uS15

MacromoleculeName: ribosomal protein uS15 / type: protein_or_peptide / ID: 44 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 17.057113 KDa
SequenceString:
GRMHAPGKGL SQSALPYRRS VPTWLKLTSD DVKEQIYKLA KKGLTPSQIG VILRDSHGVA QVRFVTGNKI LRILKSKGLA PDLPEDLYH LIKKAVAVRK HLERNRKDKD AKFRLILIES RIHRLARYYK TKRVLPPNWK YESSTASALV

UniProtKB: Small ribosomal subunit protein uS15

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Macromolecule #45: 60S ribosomal protein L19

MacromoleculeName: 60S ribosomal protein L19 / type: protein_or_peptide / ID: 45 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 21.613033 KDa
SequenceString:
SMLRLQKRLA SSVLRCGKKK VWLDPNETNE IANANSRQQI RKLIKDGLII RKPVTVHSRA RCRKNTLARR KGRHMGIGKR KGTANARMP EKVTWMRRMR ILRRLLRRYR ESKKIDRHMY HSLYLKVKGN VFKNKRILME HIHKLKADKA RKKLLADQAE A RRSKTKEA RKRREERLQA KK

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Macromolecule #46: 40S ribosomal protein S12

MacromoleculeName: 40S ribosomal protein S12 / type: protein_or_peptide / ID: 46 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 13.048244 KDa
SequenceString:
VNTALQEVLK TALIHDGLAR GIREAAKALD KRQAHLCVLA SNCDEPMYVK LVEALCAEHQ INLIKVDDNK KLGEWVGLCK IDREGKPRK VVGCSCVVVK DYGKESQAKD VIEEYFKC

UniProtKB: Small ribosomal subunit protein eS12

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Macromolecule #47: eL20

MacromoleculeName: eL20 / type: protein_or_peptide / ID: 47 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 20.827561 KDa
SequenceString:
MKASGTLREY KVVGRCLPTP KCRTPPLYRM RIFAPNHVVA KSRFWYFVSQ LKKMKKSSGE IVYCGQVFEK SPLRVKNFGI WLRYDSRSG THNMYREYRD LTTAGAVTQC YRDMGARHRA RAHSIQIMKV EEIAASKCRR PAVKQFHDSK IKFPLPHRVL R RQHKPRFT TKRPNTFF

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Macromolecule #48: eS10

MacromoleculeName: eS10 / type: protein_or_peptide / ID: 48 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 11.529682 KDa
SequenceString:
MLMPKKNRIA IYELLFKEGV MVAKKDVHMP KHPELADKNV PNLHVMKAMQ SLKSRGYVKE QFAWRHFYWY LTNEGIQYLR DYLHLPPEI VPATLRR

UniProtKB: Small ribosomal subunit protein eS10

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Macromolecule #49: eL21

MacromoleculeName: eL21 / type: protein_or_peptide / ID: 49 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 18.478791 KDa
SequenceString:
TNTKGKRRGT RYMFSRPFRK HGVVPLATYM RIYKKGDIVD IKGMGTVQKG MPHKCYHGKT GRVYNVTQHA VGIVVNKQVK GKILAKRIN VRIEHIKHSK SRDSFLKRVK ENDQKKKEAK EKGTWVQLKR QPAPPREAHF VRTNGKEPEL LEPIPYEFMA

UniProtKB: Large ribosomal subunit protein eL21

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Macromolecule #50: Ribosomal protein S15a

MacromoleculeName: Ribosomal protein S15a / type: protein_or_peptide / ID: 50 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 14.734357 KDa
SequenceString:
VRMNVLADAL KSINNAEKRG KRQVLIRPCS KVIVRFLTVM MKHGYIGEFE IIDDHRAGKI VVNLTGRLNK CGVISPRFDV QLKDLEKWQ NNLLPSRQFG FIVLTTSAGI MDHEEARRKH TGGKILGFFF

UniProtKB: Small ribosomal subunit protein uS8

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Macromolecule #51: Ribosomal protein S16

MacromoleculeName: Ribosomal protein S16 / type: protein_or_peptide / ID: 51 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 16.032804 KDa
SequenceString:
GPLQSVQVFG RKKTATAVAH CKRGNGLIKV NGRPLEMIEP RTLQYKLLEP VLLLGKERFA GVDIRVRVKG GGHVAQIYAI RQSISKALV AYYQKYVDEA SKKEIKDILI QYDRTLLVAD PRRCESKKFG GPGARARYQK SYR

UniProtKB: Small ribosomal subunit protein uS9

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Macromolecule #52: 60S ribosomal protein L22

MacromoleculeName: 60S ribosomal protein L22 / type: protein_or_peptide / ID: 52 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 11.495275 KDa
SequenceString:
QLLKFTLDCT HPVEDGIMDA ANFEQFLQER IKVNGKAGNL GGGVVSLERS KSKITVTSEV PFSKRYLKYL TKKYLKKNNL RDWLRVVAN TKESYELRYF

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Macromolecule #53: Ribosomal protein S23

MacromoleculeName: Ribosomal protein S23 / type: protein_or_peptide / ID: 53 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 15.626392 KDa
SequenceString:
GKCRGLRTAR KLRSHRRDQK WHDKQYKKAH LGTALKANPF GGASHAKGIV LEKVGVEAKQ PNSAIRKCVR VQLIKNGKKI TAFVPNDGC LNFIEENDEV LVAGFGRKGH AVGDIPGVRF KVVKVANVSL LALYKGKKER PR

UniProtKB: Small ribosomal subunit protein uS12

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Macromolecule #54: eL14

MacromoleculeName: eL14 / type: protein_or_peptide / ID: 54 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 13.972425 KDa
SequenceString:
SGAKFRISLG LPVGAVINCA DNTGAKNLYI ISVKGIKGRL NRLPAAGVGD MVMATVKKGK PELRKKVHPA VVIRQRKSYR RKDGVFLYF EDNAGVIVNN KGEMKGSAIT GPVAKECADL WPRIASNAGS IA

UniProtKB: Large ribosomal subunit protein uL14

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Macromolecule #55: Ribosomal protein L24

MacromoleculeName: Ribosomal protein L24 / type: protein_or_peptide / ID: 55 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 14.131536 KDa
SequenceString:
MKVELCSFSG YKIYPGHGRR YARTDGKVFQ FLNAKCESAF LSKRNPRQIN WTVLYRRKHK KGQSEEIQKK RTRRAVKFQR AITGASLAD IMAKRNQKPE VRKAQREQAI RAAKEAKKAK QA

UniProtKB: Large ribosomal subunit protein eL24

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Macromolecule #56: uS19

MacromoleculeName: uS19 / type: protein_or_peptide / ID: 56 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 14.246854 KDa
SequenceString:
FRKFTYRGVD LDQLLDMSYE QLMQLYSARQ RRRLSRGLRR KQHSLLKRLR KAKKEAPPME KPEVVKTHLR DMIILPEMVG SMVGVYNGK TFNQVEIKPE MIGHYLGEFS ITYKPVKHGR P

UniProtKB: Small ribosomal subunit protein uS19

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Macromolecule #57: uL23

MacromoleculeName: uL23 / type: protein_or_peptide / ID: 57 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 13.727181 KDa
SequenceString:
KIRTSPTFRR PKTLRLRRQP KYPRKSAPRR NKLDHYAIIK FPLTTESAMK KIEDNNTLVF IVDVKANKHQ IKQAVKKLYD IDVAKVNTL IRPDGEKKAY VRLAPDYDAL DVANKIGII

UniProtKB: Large ribosomal subunit protein uL23

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Macromolecule #58: Ribosomal protein L26

MacromoleculeName: Ribosomal protein L26 / type: protein_or_peptide / ID: 58 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 15.891787 KDa
SequenceString:
MKFNPFVTSD RSKNRKRHFN APSHIRRKIM SSPLSKELRQ KYNVRSMPIR KDDEVQVVRG HYKGQQIGKV VQVYRKKYVI YIERVQREK ANGTTVHVGI HPSKVVITRL KLDKDRKKIL ERKAKSRQVG KEKGK

UniProtKB: Large ribosomal subunit protein uL24

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Macromolecule #59: 60S ribosomal protein L27

MacromoleculeName: 60S ribosomal protein L27 / type: protein_or_peptide / ID: 59 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 15.704635 KDa
SequenceString:
GKFMKPGKVV LVLAGRYSGR KAVIVKNIDD GTSDRPYSHA LVAGIDRYPR KVTAAMGKKK IAKRSKIKSF VKVYNYNHLM PTRYSVDIP LDKTVVNKDV FRDPALKRKA RREAKVKFEE RYKTGKNKWF FQKLRF

UniProtKB: Large ribosomal subunit protein eL27

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Macromolecule #60: uL15

MacromoleculeName: uL15 / type: protein_or_peptide / ID: 60 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 16.489363 KDa
SequenceString:
PSRLRKTRKL RGHVSHGHGR IGKHRKHPGG RGNAGGMHHH RINFDKYHPG YFGKVGMRHY HLKRNQSFCP TVNLDKLWTL VSEQTRVNA AKNKTGAAPI IDVVRSGYYK VLGKGKLPKQ PVIVKAKFFS RRAEEKIKGV GGACVLVA

UniProtKB: Large ribosomal subunit protein uL15

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Macromolecule #61: eL29

MacromoleculeName: eL29 / type: protein_or_peptide / ID: 61 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 13.401047 KDa
SequenceString:
AKSKNHTTHN QSRKWHRNGI KKPRSQRYES LKGVDPKFLR NMRFAKKHNK KGLKKMQANN AKAMAARAEA IKALVKPKEV KPTIPKGVS RKLHRLAYIA HPKLGRRARA RIARGLR

UniProtKB: Large ribosomal subunit protein eL29

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Macromolecule #62: eL30

MacromoleculeName: eL30 / type: protein_or_peptide / ID: 62 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 10.914756 KDa
SequenceString:
SLESINSRLQ LVMKSGKYVL GYKQSLKMIR QGKAKLVILA NNCPALRKSE IEYYAMLAKT GVHHYSGNNI ELGTACGKYY RVCTLSIID PGDSDIIRS

UniProtKB: Large ribosomal subunit protein eL30

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Macromolecule #63: eL31

MacromoleculeName: eL31 / type: protein_or_peptide / ID: 63 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 12.635694 KDa
SequenceString:
NEVVTREYTI NIHKRIHGVG FKKRAPRALK EIRKFAMKEM GTPDVRIDTR LNKAVWAKGI RNVPYRIRVR LSRKRNEDED SPNKLYTLV TYVPVTTFKN LQTVNVDE

UniProtKB: Large ribosomal subunit protein eL31

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Macromolecule #64: eL32

MacromoleculeName: eL32 / type: protein_or_peptide / ID: 64 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 15.022021 KDa
SequenceString:
AALRPLVKPK IVKKRTKKFI RHQSDRYVKI KRNWRKPRGI DNRVRRRFKG QILMPNIGYG SNKKTKHMLP SGFRKFLVHN VKELEVLLM CNKSYCAEIA HNVSSKNRKA IVERAAQLAI RVTNPNARL

UniProtKB: Large ribosomal subunit protein eL32

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Macromolecule #65: eL33

MacromoleculeName: eL33 / type: protein_or_peptide / ID: 65 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 12.449612 KDa
SequenceString:
SGRLWCKAIF AGYKRGLRNQ REHTALLKIE GVYARDETEF YLGKRCAYVY KAKNNTVTPG GKPNKTRVIW GKVTRAHGNS GMVRAKFRS NLPAKAIGHR IRVMLYPSRI

UniProtKB: Large ribosomal subunit protein eL33

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Macromolecule #66: eL34

MacromoleculeName: eL34 / type: protein_or_peptide / ID: 66 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 12.994621 KDa
SequenceString:
VQRLTYRRRL SYNTASNKTR LSRTPGNRIV YLYTKKVGKA PKSACGVCPG RLRGVRAVRP KVLMRLSKTK KHVSRAYGGS MCAKCVRDR IKRAFLIEEQ KIVVKVLKAQ AQSQK

UniProtKB: Large ribosomal subunit protein eL34

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Macromolecule #67: uL29

MacromoleculeName: uL29 / type: protein_or_peptide / ID: 67 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 14.435403 KDa
SequenceString:
AKIKARDLRG KKKEELLKQL DDLKVELSQL RVAKVTGGAA SKLSKIRVVR KSIARVLTVI NQTQKENLRK FYKGKKYKPL DLRPKKTRA MRRRLNKHEE SLKTKKQQRK ERLYPLRKYA VKA

UniProtKB: Large ribosomal subunit protein uL29

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Macromolecule #68: 60S ribosomal protein L36

MacromoleculeName: 60S ribosomal protein L36 / type: protein_or_peptide / ID: 68 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 11.888371 KDa
SequenceString:
ALRYPMAVGL NKGHKVTKNV SKPRHSRRRG RLTKHTKFVR DMIREVCGFA PYERRAMELL KVSKDKRALK FIKKRVGTHI RAKRKREEL SSVLAAMRKA AAK

UniProtKB: Large ribosomal subunit protein eL36

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Macromolecule #69: Ribosomal protein L37

MacromoleculeName: Ribosomal protein L37 / type: protein_or_peptide / ID: 69 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 10.090891 KDa
SequenceString:
TKGTSSFGKR RNKTHTLCRR CGSKAYHLQK STCGKCGYPA KRKRKYNWSA KAKRRNTTGT GRMRHLKIVY RRFRHGFREG TTPKPK

UniProtKB: Large ribosomal subunit protein eL37

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Macromolecule #70: 60S ribosomal protein L38

MacromoleculeName: 60S ribosomal protein L38 / type: protein_or_peptide / ID: 70 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 8.107752 KDa
SequenceString:
PRKIEEIKDF LLTARRKDAK SVKIKKNKDN VKFKVRCSRY LYTLVITDKE KAEKLKQSLP PGLAVKELK

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Macromolecule #71: eL39

MacromoleculeName: eL39 / type: protein_or_peptide / ID: 71 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 6.324579 KDa
SequenceString:
SSHKTFRIKR FLAKKQKQNR PIPQWIWMKT GNKIRYNSKR RHWRRTKLGL

UniProtKB: Large ribosomal subunit protein eL39

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Macromolecule #72: 60S ribosomal protein L40

MacromoleculeName: 60S ribosomal protein L40 / type: protein_or_peptide / ID: 72 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 6.199574 KDa
SequenceString:
IIEPSLRQLA QKYNCDKMIC RKCYARLHPR AVNCRKKKCG HTNNLRPKKK VK

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Macromolecule #73: 60s ribosomal protein l41

MacromoleculeName: 60s ribosomal protein l41 / type: protein_or_peptide / ID: 73 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 3.473451 KDa
SequenceString:
MRAKWRKKRM RRLKRKRRKM RQRSK

UniProtKB: Small ribosomal subunit protein eS32

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Macromolecule #74: eL42

MacromoleculeName: eL42 / type: protein_or_peptide / ID: 74 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 12.198603 KDa
SequenceString:
VNVPKTRRTF CKKCGKHQPH KVTQYKKGKD SLYAQGKRRY DRKQSGYGGQ TKPIFRKKAK TTKKIVLRLE CVEPNCRSKR MLAIKRCKH FELGGDKKRK GQVIQ

UniProtKB: Large ribosomal subunit protein eL42

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Macromolecule #75: ribosomal protein eL43

MacromoleculeName: ribosomal protein eL43 / type: protein_or_peptide / ID: 75 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 10.168153 KDa
SequenceString:
AKRTKKVGIV GKYGTRYGAS LRKMVKKIEI SQHAKYTCSF CGKTKMKRRA VGIWHCGSCM KTVAGGAWTY NTTSAVTVKS AIRRLKELK DQ

UniProtKB: Large ribosomal subunit protein eL43

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Macromolecule #76: uS2

MacromoleculeName: uS2 / type: protein_or_peptide / ID: 76 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 24.361861 KDa
SequenceString: SGALDVLQMK EEDVLKFLAA GTHLGGTNLD FQMEQYIYKR KSDGIYIINL KRTWEKLLLA ARAIVAIENP ADVSVISSRN TGQRAVLKF AAATGATPIA GRFTPGTFTN QIQTAFREPR LLVVTDPRAD HQPLTEASYV NLPTIALCNT DSPLRYVDIA I PCNNKGAH ...String:
SGALDVLQMK EEDVLKFLAA GTHLGGTNLD FQMEQYIYKR KSDGIYIINL KRTWEKLLLA ARAIVAIENP ADVSVISSRN TGQRAVLKF AAATGATPIA GRFTPGTFTN QIQTAFREPR LLVVTDPRAD HQPLTEASYV NLPTIALCNT DSPLRYVDIA I PCNNKGAH SVGLMWWMLA REVLRMRGTI SREHPWEVMP DLYFYRDPEE IEKEEQAAA

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Macromolecule #77: eL28

MacromoleculeName: eL28 / type: protein_or_peptide / ID: 77 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 14.220686 KDa
SequenceString:
SAHLQWMVVR NCSSFLIKRN KQTYSTEPNN LKARNSFRYN GLIHRKTVGV EPAADGKGVV VVMKRRSGQR KPATSYVRTT INKNARATL SSIRHMIRKN KYHPDLRMAA IRRASAILRS QKPVM

UniProtKB: Large ribosomal subunit protein eL28

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Macromolecule #78: 60S acidic ribosomal protein P0

MacromoleculeName: 60S acidic ribosomal protein P0 / type: protein_or_peptide / ID: 78 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 21.521062 KDa
SequenceString: DRATWKSNYF LKIIQLLDDY PKCFIVGADN VGSKQMQQIR MSLRGKAVVL MGKNTMMRKA IRGHLENNPA LEKLLPHIRG NVGFVFTKE DLTEIRDMLL ANKVPAAARA GAIAPCEVTV PAQNTGLGPE KTSFFQALGI TTKISRGTIE ILSDVQLIKT G DKVGASEA ...String:
DRATWKSNYF LKIIQLLDDY PKCFIVGADN VGSKQMQQIR MSLRGKAVVL MGKNTMMRKA IRGHLENNPA LEKLLPHIRG NVGFVFTKE DLTEIRDMLL ANKVPAAARA GAIAPCEVTV PAQNTGLGPE KTSFFQALGI TTKISRGTIE ILSDVQLIKT G DKVGASEA TLLNMLNISP FSFGLIIQQV FDNGSIYN

UniProtKB: 60S acidic ribosomal protein P0

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Macromolecule #79: uL11

MacromoleculeName: uL11 / type: protein_or_peptide / ID: 79 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 16.561117 KDa
SequenceString:
EIKVVYLRCT GGEVGATSAL APKIGPLGLS PKKVGDDIAK ATGDWKGLRI TVKLTIQNRQ AQIEVVPSAS ALIIKALKEP PRDRKKQKN IKHSGNITFD EIVNIARQMR HRSLARELSG TIKEILGTAQ SVGCNVDGRH PHDIIDDINS GAVE

UniProtKB: Large ribosomal subunit protein uL11

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Macromolecule #80: 40S ribosomal protein S3a

MacromoleculeName: 40S ribosomal protein S3a / type: protein_or_peptide / ID: 80 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 24.759145 KDa
SequenceString: VVDPFSKKDW YDVKAPAMFN IRNIGKTLVT RTQGTKIASD GLKGRVFEVS LADLQNDEVA FRKFKLITED VQGKNCLTNF HGMDLTRDK MCSMVKKWQT MIEAHVDVKT TDGYLLRLFC VGFTKKRNNQ IRKTSYAQHQ QVRQIRKKMM EIMTREVQTN D LKEVVNKL ...String:
VVDPFSKKDW YDVKAPAMFN IRNIGKTLVT RTQGTKIASD GLKGRVFEVS LADLQNDEVA FRKFKLITED VQGKNCLTNF HGMDLTRDK MCSMVKKWQT MIEAHVDVKT TDGYLLRLFC VGFTKKRNNQ IRKTSYAQHQ QVRQIRKKMM EIMTREVQTN D LKEVVNKL IPDSIGKDIE KACQSIYPLH DVFVRKVKML KKPKFELGKL MELHG

UniProtKB: Small ribosomal subunit protein eS1

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Macromolecule #81: uS5

MacromoleculeName: uS5 / type: protein_or_peptide / ID: 81 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 24.441846 KDa
SequenceString: KEWLPVTKLG RLVKDMKIKS LEEIYLFSLP IKESEIIDFF LGASLKDEVL KIMPVQKQTR AGQRTRFKAF VAIGDYNGHV GLGVKCSKE VATAIRGAII LAKLSIVPVR RGYWGNKIGK PHTVPCKVTG RCGSVLVRLI PAPRGTGIVS APVPKKLLMM A GIDDCYTS ...String:
KEWLPVTKLG RLVKDMKIKS LEEIYLFSLP IKESEIIDFF LGASLKDEVL KIMPVQKQTR AGQRTRFKAF VAIGDYNGHV GLGVKCSKE VATAIRGAII LAKLSIVPVR RGYWGNKIGK PHTVPCKVTG RCGSVLVRLI PAPRGTGIVS APVPKKLLMM A GIDDCYTS ARGCTATLGN FAKATFDAIS KTYSYLTPDL WKETVFTKSP YQEFTDHLVK THT

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Macromolecule #82: Ribosomal protein S3

MacromoleculeName: Ribosomal protein S3 / type: protein_or_peptide / ID: 82 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 25.215586 KDa
SequenceString: MAVQISKKRK FVADGIFKAE LNEFLTRELA EDGYSGVEVR VTPTRTEIII LATRTQNVLG EKGRRIRELT AVVQKRFGFP EGSVELYAE KVATRGLCAI AQAESLRYKL LGGLAVRRAC YGVLRFIMES GAKGCEVVVS GKLRGQRAKS MKFVDGLMIH S GDPVNYYV ...String:
MAVQISKKRK FVADGIFKAE LNEFLTRELA EDGYSGVEVR VTPTRTEIII LATRTQNVLG EKGRRIRELT AVVQKRFGFP EGSVELYAE KVATRGLCAI AQAESLRYKL LGGLAVRRAC YGVLRFIMES GAKGCEVVVS GKLRGQRAKS MKFVDGLMIH S GDPVNYYV DTAVRHVLLR QGVLGIKVKI MLPWDPSGKI GPKKPLPDHV SIVEPKDEIL PTTPISEQKG

UniProtKB: Small ribosomal subunit protein uS3

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Macromolecule #83: 40S ribosomal protein S4

MacromoleculeName: 40S ribosomal protein S4 / type: protein_or_peptide / ID: 83 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 29.523674 KDa
SequenceString: ARGPKKHLKR VAAPKHWMLD KLTGVFAPRP STGPHKLREC LPLIIFLRNR LKYALTGDEV KKICMQRFIK IDGKVRTDIT YPAGFMDVI SIDKTGENFR LIYDTKGRFA VHRITPEEAK YKLCKVRKIF VGTKGIPHLV THDARTIRYP DPLIKVNDTI Q IDLETGKI ...String:
ARGPKKHLKR VAAPKHWMLD KLTGVFAPRP STGPHKLREC LPLIIFLRNR LKYALTGDEV KKICMQRFIK IDGKVRTDIT YPAGFMDVI SIDKTGENFR LIYDTKGRFA VHRITPEEAK YKLCKVRKIF VGTKGIPHLV THDARTIRYP DPLIKVNDTI Q IDLETGKI TDFIKFDTGN LCMVTGGANL GRIGVITNRE RHPGSFDVVH VKDANGNSFA TRLSNIFVIG KGNKPWISLP RG KGIRLTI AEERDKRLAA KQSSG

UniProtKB: Small ribosomal subunit protein eS4

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Macromolecule #84: Ribosomal protein S5

MacromoleculeName: Ribosomal protein S5 / type: protein_or_peptide / ID: 84 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 21.525941 KDa
SequenceString:
TPDIKLFGKW STDDVQINDI SLQDYIAVKE KYAKYLPHSA GRYAAKRFRK AQCPIVERLT NSMMMHGRNN GKKLMTVRIV KHAFEIIHL LTGENPLQVL VNAIINSGPR EDSTRIGRAG TVRRQAVDVS PLRRVNQAIW LLCTGAREAA FRNIKTIAEC L ADELINAA KGSSNSYAIK KKDELERVAK SNR

UniProtKB: Small ribosomal subunit protein uS7

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Macromolecule #85: 40S ribosomal protein S6

MacromoleculeName: 40S ribosomal protein S6 / type: protein_or_peptide / ID: 85 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 27.471535 KDa
SequenceString: MKLNISFPAT GCQKLIEVDD ERKLRTFYEK RMATEVAADA LGEEWKGYVV RISGGNDKQG FPMKQGVLTH GRVRLLLSKG HSCYRPRRT GERKRKSVRG CIVDANLSVL NLVIVKKGEK DIPGLTDTTV PRRLGPKRAS RIRKLFNLSK EDDVRQYVVR K PLNKEGKK ...String:
MKLNISFPAT GCQKLIEVDD ERKLRTFYEK RMATEVAADA LGEEWKGYVV RISGGNDKQG FPMKQGVLTH GRVRLLLSKG HSCYRPRRT GERKRKSVRG CIVDANLSVL NLVIVKKGEK DIPGLTDTTV PRRLGPKRAS RIRKLFNLSK EDDVRQYVVR K PLNKEGKK PRTKAPKIQR LVTPRVLQHK RRRIALKKQR TKKNKEEAAE YAKLLAKRMK EAKEKRQEQI AKRRRLSSL

UniProtKB: Small ribosomal subunit protein eS6

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Macromolecule #86: Signal recognition particle 54 kDa protein

MacromoleculeName: Signal recognition particle 54 kDa protein / type: protein_or_peptide / ID: 86 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Canis lupus familiaris (dog)
Molecular weightTheoretical: 47.844172 KDa
SequenceString: ADLGRKITSA LRSLSNATII NEEVLNAMLK EVCTALLEAD VNIKLVKQLR ENVKSAIDLE EMASGLNKRK MIQHAVFKEL VKLVDPGVK AWTPTKGKQN VIMFVGLQGS GKTTTCSKLA YYYQRKGWKT CLICADTFRA GAFDQLKQNA TKARIPFYGS Y TEMDPVII ...String:
ADLGRKITSA LRSLSNATII NEEVLNAMLK EVCTALLEAD VNIKLVKQLR ENVKSAIDLE EMASGLNKRK MIQHAVFKEL VKLVDPGVK AWTPTKGKQN VIMFVGLQGS GKTTTCSKLA YYYQRKGWKT CLICADTFRA GAFDQLKQNA TKARIPFYGS Y TEMDPVII ASEGVEKFKN ENFEIIIVDT SGRHKQEDSL FEEMLQVANA IQPDNIVYVM DASIGQACEA QAKAFKDKVD VA SVIVTKL DGHAKGGGAL SAVAATKSPI IFIGTGEHID DFEPFKTQPF ISKLLGMGDI EGLIDKVNEL KLDDNEALIE KLK HGQFTL RDMYEQFQNI MKMGPFSQIL GMIPGFGTDF MSKGNEQESM ARLKKLMTIM DSMNDQELDS TDGAKVFSKQ PGRI QRVAR GSGVSTRDVQ ELLTQYTKFA QMVKKM

UniProtKB: Signal recognition particle subunit SRP54

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Macromolecule #88: Signal recognition particle subunit SRP19

MacromoleculeName: Signal recognition particle subunit SRP19 / type: protein_or_peptide / ID: 88 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Canis lupus familiaris (dog)
Molecular weightTheoretical: 12.159153 KDa
SequenceString:
DRFICIYPAY LNNKKTIAEG RRIPISKAVE NPTATEIQDV CSAVGLNVFL EKNKMYSREW NRDVQYRGRV RVQLKQEDGS LCLVQFPSR KSVMLYAAEM IPKLKT

UniProtKB: Signal recognition particle 19 kDa protein

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Macromolecule #89: Signal recognition particle subunit SRP68

MacromoleculeName: Signal recognition particle subunit SRP68 / type: protein_or_peptide / ID: 89 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Canis lupus familiaris (dog)
Molecular weightTheoretical: 23.220695 KDa
SequenceString: LSLEILQIIK ESQQQHGLRH GDFQRYRGYC SRRQRRLRKT LNFKMGNRHK FTGKKVTEDL LTDNRYLLLV LMDAERAWSY AMQLKQEAN TEPRKRFHLL SRLRKAVKHA EELERLCESN RVDAKTKLEA QAYTAYLSGM LRFEHQEWKA AIEAFNKCKT I YEKLASAF ...String:
LSLEILQIIK ESQQQHGLRH GDFQRYRGYC SRRQRRLRKT LNFKMGNRHK FTGKKVTEDL LTDNRYLLLV LMDAERAWSY AMQLKQEAN TEPRKRFHLL SRLRKAVKHA EELERLCESN RVDAKTKLEA QAYTAYLSGM LRFEHQEWKA AIEAFNKCKT I YEKLASAF TEEQAVLYNQ RVEEISPNIR YCAYNIG

UniProtKB: Signal recognition particle subunit SRP68

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Macromolecule #90: Signal recognition particle 9 kDa protein

MacromoleculeName: Signal recognition particle 9 kDa protein / type: protein_or_peptide / ID: 90 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Canis lupus familiaris (dog)
Molecular weightTheoretical: 8.705137 KDa
SequenceString:
PQYQTWEEFS RAAEKLYLAD PMKARVVLKY RHSDGNLCVK VTDDLVCLVY KTDQAQDVKK IEKFHSQLMR LMVA

UniProtKB: Signal recognition particle 9 kDa protein

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Macromolecule #91: Signal recognition particle 14 kDa protein

MacromoleculeName: Signal recognition particle 14 kDa protein / type: protein_or_peptide / ID: 91 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Canis lupus familiaris (dog)
Molecular weightTheoretical: 10.651371 KDa
SequenceString:
VLLESEQFLT ELTRLFQKCR TSGSVYITLK KYDGRTKPIP RKGSVEGFEP SDNKCLLRAT DGKKKISTVV SSKEVNKFQM AYSNLLRAN MDGLK

UniProtKB: Signal recognition particle 14 kDa protein

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Macromolecule #92: Signal sequence (HR2)

MacromoleculeName: Signal sequence (HR2) / type: protein_or_peptide / ID: 92 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Homo sapiens (human)
Molecular weightTheoretical: 1.375909 KDa
SequenceString:
LLLLLLLLLL LL

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Macromolecule #3: P-tRNA

MacromoleculeName: P-tRNA / type: rna / ID: 3 / Number of copies: 1
Source (natural)Organism: Saccharomyces cerevisiae (brewer's yeast)
Molecular weightTheoretical: 24.10833 KDa
SequenceString:
GCUUCCGUAG UGCAGCGGCA GCACGUUAGG CUCAUAAUCU AAAGGUCCUU GGUUCGAAAC CAUCCGGGGG CACCA

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Macromolecule #4: E-tRNA

MacromoleculeName: E-tRNA / type: rna / ID: 4 / Number of copies: 1
Source (natural)Organism: Saccharomyces cerevisiae (brewer's yeast)
Molecular weightTheoretical: 24.148355 KDa
SequenceString:
GCCCGGAUAG CUCAGCUGUA GAGCAUCAGA CUUAAAAUCU GAGGGUCCAG GGUUCAAGUC CCUGUUCGGG CGCCA

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Macromolecule #5: mRNA

MacromoleculeName: mRNA / type: rna / ID: 5 / Number of copies: 1
Source (natural)Organism: Homo sapiens (human)
Molecular weightTheoretical: 1.877157 KDa
SequenceString:
UUAAUG

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Macromolecule #6: 28S ribosomal RNA

MacromoleculeName: 28S ribosomal RNA / type: rna / ID: 6 / Number of copies: 1
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 1.148420625 MDa
SequenceString: CGCGACCUCA GAUCAGACGU GGCGACCCGC UGAAUUUAAG CAUAUUAGUC AGCGGAGGAA AAGAAACUAA CCAGGAUUCC CUCAGUAAC GGCGAGUGAA CAGGGAAGAG CCCAGCGCCG AAUCCCCGCC CCGCGGCGGG GCGCGGGAAA UGUGGCGUAC G GAAGACCC ...String:
CGCGACCUCA GAUCAGACGU GGCGACCCGC UGAAUUUAAG CAUAUUAGUC AGCGGAGGAA AAGAAACUAA CCAGGAUUCC CUCAGUAAC GGCGAGUGAA CAGGGAAGAG CCCAGCGCCG AAUCCCCGCC CCGCGGCGGG GCGCGGGAAA UGUGGCGUAC G GAAGACCC ACUCCCCGGC GCCGGGGGGC CCAAGUCCUU CUGAUCGAGG CCCAGCCCGU GGACGGUGUG AGGCCGGUAG CG GCCCCCG GCGCGCCGGG CCCGGGUCUU CCCGGAGUCG GGUUGCUUGG GAAUGCAGCC CAAAGCGGGU GGUAAACUCC AUC UAAGGC UAAAUACCGG CACGAGACCG AUAGUCAACA AGUACCGUAA GGGAAAGUUG AAAAGAACUU UGAAGAGAGA GUUC AAGAG GGCGUGAAAC CGUUAAGAGG UAAACGGGUG GGGUCCGCGC AGUCCGCCCG GAGGAUUCAA CCCGGCGGCG CGGUC CGGC CGUGCCGGCG GGGCGGAUCU CCCGCUCCCG UCGGCGGGGG ACCGCCCCCC GGCCGGCGAC CGGCCGCCGC CGGGCG CAU UUCCACCGCG GCGGUGCGCC GCGACCGGCU CCGGGACGGC UGGGAAGGCC CCGGCGGGGA AGGUGGCCCG GGGGCCC CG GGUGUUACAG CCCCGCCCCG GCAGCAGCAG CUCGCCGAAU CCCGGGGCCG AGGGAGCGAG ACCCGUGCGC CGCGCUCU C CCCCCUCGGG GGGGCCGGGC CACCCCUCCC ACGGCGCGAC CGCUGGGGCG GACUGUCCAG UGCGCCCCGG GCGGGUCGC GCCGUCGGGC CCGGGGGGCC ACGCGUCCCC CGCGAGCGCA CGGGGUCGGC GGCGAUGUCG GCUACCCACC CGACCCGUCU UGAAACACG GACCAAGGAG UCUAACACGU GCGCGAGUCG GGGGCUACGA AAGCCGCCGU GGCGCAAUGA AGGUGAAGGC C GGCGCGCG CGCCGCCGGC CGAGGUGGGA UCCCGAGGCC UUCCAGUCCG CCGAGGGCGC ACCACCGGCC CGUCUCGCCC GC CGCGCCG GGGAGGUGGA GCACGAGCGC ACGUGUUAGG ACCCGAAAGA UGGUGAACUA UGCCUGGGCA GGGCGAAGCC AGA GGAAAC UCUGGUGGAG GUCCGUAGCG GUCCUGACGU GCGAAUCGGU CGUCCGACCU GGGUAUAGGG GCGAAAGACU AAUC GAACC AUCUAGUAGC UGGUUCCCUC CAAAGUUUCC CUCAGGAUAG CUGGCGCUCU CCGCAGUUUU AUCCGGUAAA GCGAA UGAU UAGAGGUCUU GGGGCCGAAA CGAUCUCAAC CUAUUCUCAA ACUUUAAAUG GGUAAGAAGC CCGGCUCGCU GGUGUG GAG CCGGGCGUGG AAUGCGAGUG CCUAGUGGGC CACUUUUGGU AAGCAGAACU GGCGCUGCGG GAUGAACCGA ACGCCGG GU UAAGGCGCCC GAUGCCGACG CUCAUCAGAC CCCAGAAAAG GUGUUGGUUG AUAUAGACAG CAGGAUGGUG GCCAUGGA A GUCGGAAUCC GCUAAGGAGU GUGUAACAAC UCACCUGCCG AAUCAACUAG CCCUGAAAAU GGAUGGCGCU GGAGCGUCG GGCCCAUACC CGGCCGUCGC UGGCAGUCGG CAGAGCGAGA AAGAGAGUGG CGCGGACGCU ACGCCGCGAC GAGUAGGAGG GCCGCUGCG GUGAGCCUUG AAGCCUAGGG CGCGGGCCCG GGUGGAGCCG CCGCAGGUGC AGAUCUUGGU GGUAGUAGCA A AUAUUCAA ACGAGAACUU UGAAGGCCGA AGUGGAGAAG GGUUCCAUGU GAACAGCAGU UGAACAUGGG UCAGUCGGUC CU GAGAGAU GGGCGAGCGC CGUUCCGAAG GGACGGGCGA UGGCCUCCGU UGCCCUCAGC CGAUCGAAAG GGAGUCGGGU UCA GAUCCC CGAAUCCGGA GUGGCGGAGA UGGGCGCCGC GAGGCGUCCA GUGCGGUAAC GCGACCGAUC CCGGAGAAGC CGGC GGGAG CCCCGGGGAG AGUUCUCUUU UCUUUGUGAA GGGCAGGGCG CCCUGGAAUG GGUUCGCCCC GAGAGAGGGG CCCGU GCCU UGGAAAGCGU CGCGGUUCCG GCGGCGUCCG GUGAGCUCUC GCUGGCCCUU GAAAAUCCGG GGGAGAGGGU GUAAAU CUC GCGCCGGGCC GUACCCAUAU CCGCAGCAGG UCUCCAAGGU GAACAGCCUC UGGCAUGUUG GAACAAUGUA GGUAAGG GA AGUCGGCAAG CCGGAUCCGU AACUUCGGGA UAAGGAUUGG CUCUAAGGGC UGGCAGCCGA CUUAGAACUG GUGCGGAC C AGGGGAAUCC GACUGUUUAA UUAAAACAAA GCAUCGCGAA GGCCCGCGGC GGGUGUUGAC GCGAUGUGAU UUCUGCCCA GUGCUCUGAA UGUCAAAGUG AAGAAAUUCA AUGAAGCGCG GGUAAACGGC GGGAGUAACU AUGACUCUCU UAAGGUAGCC AAAUGCCUC GUCAUCUAAU UAGUGACGCG CAUGAAUGGA UGAACGAGAU UCCCACUGUC CCUACCUACU AUCCAGCGAA A CCACAGCC AAGGGAACGG GCUUGGCGGA AUCAGCGGGG AAAGAAGACC CUGUUGAGCU UGACUCUAGU CUGGCACGGU GA AGAGACG UUUUUUCACU GACCCGGUGA GGCGGGGGGG CGAGCCGGGC UCUCGCUUCU GGCGCCAAGC GCCCGGCCGG CCG GGCGCG ACCCGCUCCG GGGACAGUGC CAGGUGGGGA GUUUGACUGG GGCGGUACAC CUGUCAAACG GUAACGCAGG UGUC CUAAG GCGAGCUCAG GGAGGACAGA AACCUCCCGU GGAGCAGAAG GGCAAAAGCU CGCUUGAUCU UGAUUUUCAG UACGA AUAC AGACCGUGAA AGCGGGGCCU CACGAUCCUU CUGACCUUUU GGGUUUUAAG CAGGAGGUGU CAGAAAAGUU ACCACA GGG AUAACUGGCU UGUGGCGGCC AAGCGUUCAU AGCGACGUCG CUUUUUGAUC CUUCGAUGUC GGCUCUUCCU AUCAUUG UG AAGCAGAAUU CACCAAGCGU UGGAUUGUUC ACCCACUAAU AGGGAACGUG AGCUGGGUUU AGACCGUCGU GAGACAGG U UAGUUUUACC CUACUGAUGA UGUGUUGUUG CCAUGGUAAU CCUGCUCAGU ACGAGAGGAA CCGCAGGUUC AGACAUUUG GUGUAUGUGC UUGGCUGAGG AGCCAAUGGG GCGAAGCUAC CAUCUGUGGG AUUAUGACUG AACGCCUCUA AGUCAGAAUC CCGCCCAGG CGGAACGAUA GCGCCGGAGC CUCGGUUGGC CUCGGAUAGC CGGUCCCCCG CCGGGGUCCG GUGCGGAGAG C CCUUCGUC CCGGGAAACG GGGCGGCCGG AAAGGGGGCC GCCCUCUCGC CCGUCACGCA CCGCACGUUC GUGGGGAACC UG GCGCUAA ACCAUUCGUA GACGACCUGC UUCUGGGUCG GGGUUUCGUA CGUAGCAGAG CAGCUGCUGC GAUCUAUUGA AAG UCAGCC CUCGACACAA GGGUUUGU

+
Macromolecule #8: 5S ribosomal RNA

MacromoleculeName: 5S ribosomal RNA / type: rna / ID: 8 / Number of copies: 1
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 38.691914 KDa
SequenceString:
GUCUACGGCC AUACCACCCU GAACGCGCCC GAUCUCGUCU GAUCUCGGAA GCUAAGCAGG GUCGGGCCUG GUUAGUACUU GGAUGGGAG ACCGCCUGGG AAUACCGGGU GCUGUAGGCU U

+
Macromolecule #9: 5.8S ribosomal RNA

MacromoleculeName: 5.8S ribosomal RNA / type: rna / ID: 9 / Number of copies: 1
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 48.545672 KDa
SequenceString:
CGACUCUUAG CGGUGGAUCA CUCGGCUCGU GCGUCGAUGA AGAACGCAGC UAGCUGCGAG AAUUAAUGUG AAUUGCAGGU UGAUCAUCG ACACUUCGAA CGCACUUGCG GCCCCGGGUU CCUCCCGGGG CUACGCCUGU CUGAGCGUCG CU

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Macromolecule #31: 18S ribosomal RNA

MacromoleculeName: 18S ribosomal RNA / type: rna / ID: 31 / Number of copies: 1
Source (natural)Organism: Oryctolagus cuniculus (rabbit)
Molecular weightTheoretical: 548.040188 KDa
SequenceString: UACCUGGUUG AUCCUGCCAG UAGCAUAUGC UUGUCUCAAA GAUUAAGCCA UGCAUGUCUA AGUACGCACG GCCGGUACAG UGAAACUGC GAAUGGCUCA UUAAAUCAGU UAUGGUUCCU UUGGUCGCUC GUACUUGGAU AACUGUGGUA AUUCUAGAGC U AAUACAUG ...String:
UACCUGGUUG AUCCUGCCAG UAGCAUAUGC UUGUCUCAAA GAUUAAGCCA UGCAUGUCUA AGUACGCACG GCCGGUACAG UGAAACUGC GAAUGGCUCA UUAAAUCAGU UAUGGUUCCU UUGGUCGCUC GUACUUGGAU AACUGUGGUA AUUCUAGAGC U AAUACAUG CCGACGGGCG CUGACCCCCU UCGCGGGGGG GAUGCGUGCA UUUAUCAGUG GUGACUCUAG AUAACCUCGG GC CGAUCGC ACGCCCGGCG GCGACGACCC AUUCGAACGU CUGCCCUAUC AACUUUCGAU GGUAGUCGCC GUGCCUACCA UGG UGACCA CGGGUGACGG GGAAUCAGGG UUCGAUUCCG GAGAGGGAGC CUGAGAAACG GCUACCACAU CCAAGGAAGG CAGC AGGCG CGCAAAUUAC CCACUCCCGA CCCGGGGAGG UAGUGACGAA AAAUAACAAU ACAGGACUCU UUCGAGGCCC UGUAA UUGG AAUGAGUCCA CUUUAAAUCC UUUAACGAGG AUCCAUUGGA GGGCAAGUCU GGUGCCAGCA GCCGCGGUAA UUCCAG CUC CAAUAGCGUA UAUUAAAGUU GCUGCAGUUA AAAAGCUCGU AGUUGGAUCU UGGGAGCGGC CGUCCCCUGC UCGGCGC CG GCCCGAAGCG UUUACUUUGA AAAAAUUAGA GUGUUCAAAG CAGGCCGCCU GGAUACCGCA GCUAGGAAUA AUGGAAUA G GACCGCGGUU CUAUUUUGUU GGUUUUCGGA ACUGAGGCCA UGAUUAAGAG GGACGGCCGG GGGCAUUCGU AUUGCGCCG CUAGAGGUGA AAUUCUUGGA CCGGCGCAAG ACGGACCAGA GCGAAAGCAU UUGCCAAGAA UGUUUUCAUU AAUCAAGAAC GAAAGUCGG AGGUUCGAAG ACGAUCAGAU ACCGUCGUAG UUCCGACCAU AAACGAUGCC GACUGGCGAU GCGGCGGCGU U AUUCCCAU GACCCGCCGG GCAGCUUCCG GGAAACCAAA GUCUUUGGGU UCCGGGGGGA GUAUGGUUGC AAAGCUGAAA CU UAAAGGA AUUGACGGAA GGGCACCACC AGGAGUGGAG CCUGCGGCUU AAUUUGACUC AACACGGGAA ACCUCACCCG GCC CGGACA CGGACAGGAU UGACAGAUUG AUAGCUCUUU CUCGAUUCCG UGGGUGGUGG UGCAUGGCCG UUCUUAGUUG GUGG AGCGA UUUGUCUGGU UAAUUCCGAU AACGAACGAG ACUCUGGCAU GCUAACUAGU UACGCGACCC CGGUCGGCGU AACUU CUUA GAGGGACAAG UGGCGUUCAG CCACCCGAGA UUGAGCAAUA ACAGGUCUGU GAUGCCCUUA GAUGUCCGGG GCUGCA CGC GCGCUACACU GACUGGCUCA GCGUGUGCCU ACCCUACGCC GGCAGGCGCG GGUAACCCGU UGAACCCCAU UCGUGAU GG GGAUCGGGGA UUGCAAUUAU UCCCCAUGAA CGAGGAAUUC CCAGUAAGUG CGGGUCAUAA GCUUGCGUUG AUUAAGUC C CUGCCCUUUG UACACACCGC CCGUCGCUAC UACCGAUUGG AUGGUUUAGU GAGGCCCUCG GAUCGGCCCC GCCGGGGUG CCCUGGCGGA GCGCUGAGAA GACGGUCGAA CUUGACUAUC UAGAGGAAGU AAAAGUCGUA ACAAGGUUUC CGUAGGUGAA CCUGCGGAA GGAUCAUUA

+
Macromolecule #87: 7S RNA

MacromoleculeName: 7S RNA / type: rna / ID: 87 / Number of copies: 1
Source (natural)Organism: Canis lupus familiaris (dog)
Molecular weightTheoretical: 66.779688 KDa
SequenceString: GCCGGGCGCG GUGGCGCGCG CCUGUAGUCC CAGCUACUCG GGAGGCUGAG GCUGGAGGAU CGCUUGACUA AGUUCGGCAU CAAUAUGGU GACCUCCCGG GAGCGGGGGA CCACCAGGUU GCCUAAGGAG GGGUGAACCG GCCCAGGUCG GAAACGGAGC A GGUCAAAA ...String:
GCCGGGCGCG GUGGCGCGCG CCUGUAGUCC CAGCUACUCG GGAGGCUGAG GCUGGAGGAU CGCUUGACUA AGUUCGGCAU CAAUAUGGU GACCUCCCGG GAGCGGGGGA CCACCAGGUU GCCUAAGGAG GGGUGAACCG GCCCAGGUCG GAAACGGAGC A GGUCAAAA CUCCCGUGCU GAUCAGUAGU UUAGCGAGAC CCCGUCUC

+
Macromolecule #93: MAGNESIUM ION

MacromoleculeName: MAGNESIUM ION / type: ligand / ID: 93 / Number of copies: 299 / Formula: MG
Molecular weightTheoretical: 24.305 Da

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Macromolecule #94: ZINC ION

MacromoleculeName: ZINC ION / type: ligand / ID: 94 / Number of copies: 5 / Formula: ZN
Molecular weightTheoretical: 65.409 Da

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Experimental details

-
Structure determination

Methodcryo EM
Processingsingle particle reconstruction
Aggregation stateparticle

-
Sample preparation

BufferpH: 7.5
VitrificationCryogen name: ETHANE

-
Electron microscopy

MicroscopeFEI TITAN KRIOS
Image recordingFilm or detector model: FEI FALCON II (4k x 4k) / Average electron dose: 28.0 e/Å2
Electron beamAcceleration voltage: 300 kV / Electron source: FIELD EMISSION GUN
Electron opticsIllumination mode: SPOT SCAN / Imaging mode: BRIGHT FIELD
Experimental equipment
Model: Titan Krios / Image courtesy: FEI Company

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Image processing

Startup modelType of model: PDB ENTRY
PDB model - PDB ID:

5lzv

Final reconstructionApplied symmetry - Point group: C1 (asymmetric) / Resolution.type: BY AUTHOR / Resolution: 3.7 Å / Resolution method: FSC 0.143 CUT-OFF / Software - Name: RELION / Number images used: 24875
Initial angle assignmentType: OTHER / Software - Name: RELION / Details: RELION
Final angle assignmentType: OTHER / Software - Name: RELION / Details: RELION
FSC plot (resolution estimation)

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Atomic model buiding 1

RefinementProtocol: RIGID BODY FIT
Output model

PDB-6r6g:
Structure of XBP1u-paused ribosome nascent chain complex with SRP.

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