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- EMDB-14191: Ternary complex of ribosome nascent chain with SRP and NAC -

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基本情報

登録情報
データベース: EMDB / ID: EMD-14191
タイトルTernary complex of ribosome nascent chain with SRP and NAC
マップデータTernary ribosome-nascent chain, SRP and NAC complex
試料
  • 複合体: Ternary ribosome-nascent chain SRP NAC complex
    • 複合体: Ribosome
      • タンパク質・ペプチド: x 43種
      • RNA: x 3種
    • 複合体: SRP RNA 7SL
      • RNA: x 1種
    • 複合体: Signal recognition particle proteins
      • タンパク質・ペプチド: x 3種
    • 複合体: Nascent chain preprolactin
      • タンパク質・ペプチド: x 1種
    • 複合体: Isoform 2 of Transcription factor BTF3
      • タンパク質・ペプチド: x 1種
  • リガンド: x 2種
キーワードRibosome / SRP / NAC / nascent chain / co-translational / Endoplasmic reticulum / co-translational protein targeting / co-translational folding
機能・相同性
機能・相同性情報


PI3K Cascade / PIP3 activates AKT signaling / FLT3 Signaling / Negative regulation of FLT3 / FLT3 signaling through SRC family kinases / RAF/MAP kinase cascade / negative regulation of protein localization to endoplasmic reticulum / nascent polypeptide-associated complex / negative regulation of striated muscle cell apoptotic process / regulation of skeletal muscle fiber development ...PI3K Cascade / PIP3 activates AKT signaling / FLT3 Signaling / Negative regulation of FLT3 / FLT3 signaling through SRC family kinases / RAF/MAP kinase cascade / negative regulation of protein localization to endoplasmic reticulum / nascent polypeptide-associated complex / negative regulation of striated muscle cell apoptotic process / regulation of skeletal muscle fiber development / SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition / positive regulation of cell proliferation involved in heart morphogenesis / endoplasmic reticulum signal peptide binding / PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling / signal recognition particle, endoplasmic reticulum targeting / Major pathway of rRNA processing in the nucleolus and cytosol / GTP hydrolysis and joining of the 60S ribosomal subunit / positive regulation of skeletal muscle tissue growth / cardiac ventricle development / L13a-mediated translational silencing of Ceruloplasmin expression / SRP-dependent cotranslational protein targeting to membrane / Formation of a pool of free 40S subunits / Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) / Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) / granulocyte differentiation / signal recognition particle binding / signal recognition particle / cotranslational protein targeting to membrane / protein targeting to ER / signal-recognition-particle GTPase / dendritic cell differentiation / SRP-dependent cotranslational protein targeting to membrane, translocation / heart trabecula morphogenesis / 7S RNA binding / skeletal muscle tissue regeneration / SRP-dependent cotranslational protein targeting to membrane / exocrine pancreas development / ribosomal subunit / embryonic hemopoiesis / exit from mitosis / optic nerve development / retinal ganglion cell axon guidance / positive regulation of signal transduction by p53 class mediator / ubiquitin ligase inhibitor activity / SRP-dependent cotranslational protein targeting to membrane / ribonucleoprotein complex binding / protein-RNA complex assembly / rough endoplasmic reticulum / MDM2/MDM4 family protein binding / neutrophil chemotaxis / B cell differentiation / maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / ribosomal large subunit biogenesis / cytokine activity / wound healing / receptor tyrosine kinase binding / antimicrobial humoral immune response mediated by antimicrobial peptide / GDP binding / protein transport / regulation of translation / large ribosomal subunit / retina development in camera-type eye / 5S rRNA binding / ribosomal large subunit assembly / large ribosomal subunit rRNA binding / defense response to Gram-negative bacterium / killing of cells of another organism / cytosolic large ribosomal subunit / in utero embryonic development / cytoplasmic translation / transcription coactivator activity / tRNA binding / postsynaptic density / rRNA binding / nuclear speck / nuclear body / ribosome / structural constituent of ribosome / protein domain specific binding / translation / response to xenobiotic stimulus / ribonucleoprotein complex / focal adhesion / GTPase activity / mRNA binding / positive regulation of cell population proliferation / synapse / GTP binding / nucleolus / negative regulation of transcription by RNA polymerase II / cell surface / endoplasmic reticulum / positive regulation of transcription by RNA polymerase II / ATP hydrolysis activity / DNA binding / extracellular space / RNA binding / extracellular exosome / zinc ion binding / nucleus
類似検索 - 分子機能
Flt3 ligand / flt3 ligand / Transcription factor BTF3 / Nascent polypeptide-associated complex NAC domain / Nascent polypeptide-associated complex subunit alpha / NAC A/B domain superfamily / NAC domain / NAC A/B domain profile. / NAC / Nascent polypeptide-associated complex subunit alpha-like, UBA domain ...Flt3 ligand / flt3 ligand / Transcription factor BTF3 / Nascent polypeptide-associated complex NAC domain / Nascent polypeptide-associated complex subunit alpha / NAC A/B domain superfamily / NAC domain / NAC A/B domain profile. / NAC / Nascent polypeptide-associated complex subunit alpha-like, UBA domain / HYPK UBA domain / Signal recognition particle subunit SRP68 / Signal recognition particle subunit SRP68, RNA-binding domain / SRP68, N-terminal domain superfamily / RNA-binding signal recognition particle 68 / Signal recognition particle, SRP54 subunit, eukaryotic / Signal recognition particle, SRP19 subunit / Signal recognition particle, subunit SRP19-like superfamily / SRP19 protein / SRP/SRP receptor, N-terminal / Signal recognition particle, SRP54 subunit / Signal recognition particle, SRP54 subunit, M-domain / Signal recognition particle, SRP54 subunit, M-domain superfamily / Signal peptide binding domain / SRP54-type proteins GTP-binding domain signature. / Signal recognition particle SRP54, helical bundle / Signal recognition particle SRP54, N-terminal domain superfamily / SRP54-type protein, helical bundle domain / SRP54-type protein, helical bundle domain / Signal recognition particle, SRP54 subunit, GTPase domain / SRP54-type protein, GTPase domain / SRP54-type protein, GTPase domain / Four-helical cytokine-like, core / Ribosomal protein L6, N-terminal / Ribosomal protein L6, N-terminal domain / Ribosomal protein L30e / Ribosomal protein L2, archaeal-type / Ribosomal L15/L27a, N-terminal / Ribosomal protein L28e / Ribosomal protein L23 / Ribosomal L28e/Mak16 / Ribosomal L28e protein family / metallochaperone-like domain / TRASH domain / Ribosomal protein L41 / Ribosomal protein L41 / Ribosomal protein L29e / Ribosomal L29e protein family / Ribosomal protein L10e, conserved site / Ribosomal protein L10e signature. / Ribosomal protein L27e, conserved site / Ribosomal protein L27e signature. / Ribosomal protein L10e / Ribosomal protein L38e / Ribosomal protein L38e superfamily / Ribosomal L38e protein family / Ribosomal protein L44e signature. / Ribosomal protein L24e, conserved site / Ribosomal protein L24e signature. / : / Ribosomal protein L19, eukaryotic / Ribosomal protein L19/L19e conserved site / Ribosomal protein L19e signature. / Ribosomal protein L6e signature. / : / Ribosomal protein L44e / Ribosomal protein L44 / : / Ribosomal protein L34e, conserved site / Ribosomal protein L34e signature. / Ribosomal protein L5 eukaryotic, C-terminal / Ribosomal L18 C-terminal region / Ribosomal protein L30e signature 1. / Ribosomal L40e family / Ribosomal protein L23/L25, N-terminal / Ribosomal protein L23, N-terminal domain / Ribosomal_L40e / Ribosomal protein L40e / Ribosomal protein L40e superfamily / Eukaryotic Ribosomal Protein L27, KOW domain / Ribosomal Protein L6, KOW domain / Ribosomal protein L30e signature 2. / Ribosomal protein L27e / Ribosomal protein L27e superfamily / Ribosomal L27e protein family / Ribosomal protein L36e signature. / Ribosomal protein L35Ae, conserved site / Ribosomal protein L30e, conserved site / Ribosomal protein L35Ae signature. / Ribosomal protein L39e, conserved site / Ribosomal protein L39e signature. / : / Ribosomal protein L6e / Ribosomal protein L34Ae / Ribosomal protein L34e / 60S ribosomal protein L19 / Ribosomal protein L30/YlxQ / Ribosomal protein L7A/L8 / 60S ribosomal protein L6E / 60S ribosomal protein L35
類似検索 - ドメイン・相同性
Small ribosomal subunit protein eS32 / Fms related receptor tyrosine kinase 3 ligand / Ubiquitin-ribosomal protein eL40 fusion protein / Ribosomal protein L36a / Large ribosomal subunit protein eL38 / Large ribosomal subunit protein uL16 / Large ribosomal subunit protein eL24 / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL33 / Large ribosomal subunit protein eL31 ...Small ribosomal subunit protein eS32 / Fms related receptor tyrosine kinase 3 ligand / Ubiquitin-ribosomal protein eL40 fusion protein / Ribosomal protein L36a / Large ribosomal subunit protein eL38 / Large ribosomal subunit protein uL16 / Large ribosomal subunit protein eL24 / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL33 / Large ribosomal subunit protein eL31 / Large ribosomal subunit protein eL21 / Large ribosomal subunit protein uL29 / Large ribosomal subunit protein eL6 / Large ribosomal subunit protein uL15 / Large ribosomal subunit protein uL24 / Large ribosomal subunit protein eL8 / Large ribosomal subunit protein uL30 / Large ribosomal subunit protein uL4 / Large ribosomal subunit protein uL6 / Large ribosomal subunit protein eL43 / Large ribosomal subunit protein uL18 / Large ribosomal subunit protein eL39 / Large ribosomal subunit protein eL15 / Large ribosomal subunit protein uL14 / Large ribosomal subunit protein eL30 / Large ribosomal subunit protein uL3 / Large ribosomal subunit protein eL29 / Uncharacterized protein / Large ribosomal subunit protein uL2 / Large ribosomal subunit protein eL36 / Large ribosomal subunit protein uL5 / Large ribosomal subunit protein eL32 / Large ribosomal subunit protein eL27 / Large ribosomal subunit protein eL28 / Large ribosomal subunit protein eL34 / Signal recognition particle 19 kDa protein / Transcription factor BTF3 / Signal recognition particle subunit SRP54 / Nascent polypeptide-associated complex subunit alpha / Large ribosomal subunit protein eL19 / Signal recognition particle subunit SRP68 / Large ribosomal subunit protein eL14 / Large ribosomal subunit protein eL37
類似検索 - 構成要素
生物種Oryctolagus cuniculus (ウサギ) / Homo sapiens (ヒト)
手法単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 2.83 Å
データ登録者Jomaa A / Gamerdinger M / Hsieh H / Wallisch A / Chandrasekaran V / Ulusoy Z / Scaiola A / Hegde R / Shan S / Ban N / Deuerling E
資金援助 スイス, 1件
OrganizationGrant number国
Swiss National Science Foundation スイス
引用ジャーナル: Science / 年: 2022
タイトル: Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting.
著者: Ahmad Jomaa / Martin Gamerdinger / Hao-Hsuan Hsieh / Annalena Wallisch / Viswanathan Chandrasekaran / Zeynel Ulusoy / Alain Scaiola / Ramanujan S Hegde / Shu-Ou Shan / Nenad Ban / Elke Deuerling /
要旨: The nascent polypeptide-associated complex (NAC) interacts with newly synthesized proteins at the ribosomal tunnel exit and competes with the signal recognition particle (SRP) to prevent mistargeting ...The nascent polypeptide-associated complex (NAC) interacts with newly synthesized proteins at the ribosomal tunnel exit and competes with the signal recognition particle (SRP) to prevent mistargeting of cytosolic and mitochondrial polypeptides to the endoplasmic reticulum (ER). How NAC antagonizes SRP and how this is overcome by ER targeting signals are unknown. Here, we found that NAC uses two domains with opposing effects to control SRP access. The core globular domain prevented SRP from binding to signal-less ribosomes, whereas a flexibly attached domain transiently captured SRP to permit scanning of nascent chains. The emergence of an ER-targeting signal destabilized NAC's globular domain and facilitated SRP access to the nascent chain. These findings elucidate how NAC hands over the signal sequence to SRP and imparts specificity of protein localization.
履歴
登録2022年1月25日-
ヘッダ(付随情報) 公開2022年3月16日-
マップ公開2022年3月16日-
更新2024年7月17日-
現状2024年7月17日処理サイト: PDBe / 状態: 公開

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構造の表示

ムービー
  • 表面図（断面を密度値に従い着色）
  • 表面レベル: 0.035
  • UCSF Chimeraによる作画
  • ダウンロード
  • 表面図（高さに従い着色）
  • 表面レベル: 0.035
  • UCSF Chimeraによる作画
  • ダウンロード
  • あてはめたモデルとの重ね合わせ
  • 原子モデル: PDB-7qwq
  • 表面レベル: 0.027
  • UCSF Chimeraによる作画
  • ダウンロード
ムービービューア
構造ビューアEMマップ:
SurfViewMolmilJmol/JSmol
添付画像

emd_14191.png

ダウンロードとリンク

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マップ

ファイルダウンロード / ファイル: emd_14191.map.gz / 形式: CCP4 / 大きさ: 343 MB / タイプ: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
注釈Ternary ribosome-nascent chain, SRP and NAC complex
投影像・断面図

画像のコントロール

大きさ
明度
コントラスト
その他
軸Z (Sec.)Y (Row.)X (Col.)
1.08 Å/pix.
x 448 pix.
= 483.84 Å		1.08 Å/pix.
x 448 pix.
= 483.84 Å		1.08 Å/pix.
x 448 pix.
= 483.84 Å

表面

投影像

断面 (1/3)

断面 (1/2)

断面 (2/3)

画像は Spider により作成

ボクセルのサイズX=Y=Z: 1.08 Å
密度

ヒストグラム

ヒストグラム (対数)
表面レベル登録者による: 0.027 / ムービー #1: 0.035
最小 - 最大-0.09441678 - 0.2096099
平均 (標準偏差)0.00049410004 (±0.0102524785)
対称性空間群: 1
詳細

EMDB XML:

マップ形状
Axis orderXYZ
Origin000
サイズ448448448
Spacing448448448
セルA=B=C: 483.84003 Å
α=β=γ: 90.0 °

CCP4マップ ヘッダ情報:

modeImage stored as Reals
Å/pix. X/Y/Z1.081.081.08
M x/y/z448448448
origin x/y/z0.0000.0000.000
length x/y/z483.840483.840483.840
α/β/γ90.00090.00090.000
MAP C/R/S123
start NC/NR/NS000
NC/NR/NS448448448
D min/max/mean-0.0940.2100.000

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添付データ

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試料の構成要素

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全体 : Ternary ribosome-nascent chain SRP NAC complex

全体名称: Ternary ribosome-nascent chain SRP NAC complex
要素
  • 複合体: Ternary ribosome-nascent chain SRP NAC complex
    • 複合体: Ribosome
      • タンパク質・ペプチド: L8
      • タンパク質・ペプチド: 60S ribosomal protein L29
      • RNA: 28S rRNA
      • タンパク質・ペプチド: uL3
      • タンパク質・ペプチド: 60S ribosomal protein L30
      • タンパク質・ペプチド: 60S ribosomal protein L4
      • タンパク質・ペプチド: Ribosomal protein L31
      • タンパク質・ペプチド: Ribosomal_L18_c domain-containing protein
      • タンパク質・ペプチド: Ribosomal protein L32
      • タンパク質・ペプチド: 60S ribosomal protein L6
      • タンパク質・ペプチド: 60S ribosomal protein L35a
      • タンパク質・ペプチド: uL30
      • タンパク質・ペプチド: 60S ribosomal protein L34
      • タンパク質・ペプチド: 60S ribosomal protein L7a
      • タンパク質・ペプチド: 60S ribosomal protein L35
      • タンパク質・ペプチド: 60S ribosomal protein L9
      • タンパク質・ペプチド: 60S ribosomal protein L36
      • タンパク質・ペプチド: 60S ribosomal protein L10
      • タンパク質・ペプチド: Ribosomal protein L37
      • タンパク質・ペプチド: Ribosomal protein L11
      • タンパク質・ペプチド: 60S ribosomal protein L38
      • タンパク質・ペプチド: 60S ribosomal protein L13
      • タンパク質・ペプチド: Ribosomal protein L39
      • タンパク質・ペプチド: 60S ribosomal protein L14
      • タンパク質・ペプチド: Ubiquitin A-52 residue ribosomal protein fusion product 1
      • タンパク質・ペプチド: Ribosomal protein L15
      • タンパク質・ペプチド: 60s ribosomal protein l41
      • タンパク質・ペプチド: 60S ribosomal protein L13a
      • タンパク質・ペプチド: eL42
      • タンパク質・ペプチド: 60S ribosomal protein L17
      • タンパク質・ペプチド: eL43
      • タンパク質・ペプチド: eL18
      • タンパク質・ペプチド: 60S ribosomal protein L28
      • タンパク質・ペプチド: 60S ribosomal protein L19
      • タンパク質・ペプチド: 60S ribosomal protein L18a
      • タンパク質・ペプチド: 60S ribosomal protein L21
      • タンパク質・ペプチド: Ribosomal protein L22
      • タンパク質・ペプチド: Ribosomal protein L23
      • タンパク質・ペプチド: Ribosomal protein L24
      • タンパク質・ペプチド: Ribosomal_L23eN domain-containing protein
      • RNA: 5S ribosomal RNA
      • タンパク質・ペプチド: Ribosomal protein L26
      • RNA: 5.8S ribosomal RNA
      • タンパク質・ペプチド: 60S ribosomal protein L27
      • タンパク質・ペプチド: 60S ribosomal protein L27a
      • タンパク質・ペプチド: Nascent polypeptide-associated complex subunit alpha
    • 複合体: SRP RNA 7SL
      • RNA: SRP RNA 7SL
    • 複合体: Signal recognition particle proteins
      • タンパク質・ペプチド: Signal recognition particle 19 kDa protein
      • タンパク質・ペプチド: Signal recognition particle subunit SRP68
      • タンパク質・ペプチド: Signal recognition particle 54 kDa protein
    • 複合体: Nascent chain preprolactin
      • タンパク質・ペプチド: Nascent chain preprolactin
    • 複合体: Isoform 2 of Transcription factor BTF3
      • タンパク質・ペプチド: Isoform 2 of Transcription factor BTF3
  • リガンド: MAGNESIUM ION
  • リガンド: ZINC ION

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超分子 #1: Ternary ribosome-nascent chain SRP NAC complex

超分子名称: Ternary ribosome-nascent chain SRP NAC complex / タイプ: complex / ID: 1 / 親要素: 0 / 含まれる分子: #1-#52

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超分子 #2: Ribosome

超分子名称: Ribosome / タイプ: complex / ID: 2 / 親要素: 1 / 含まれる分子: #7-#52
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)

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超分子 #3: SRP RNA 7SL

超分子名称: SRP RNA 7SL / タイプ: complex / ID: 3 / 親要素: 1 / 含まれる分子: #1
由来(天然)生物種: Homo sapiens (ヒト)

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超分子 #4: Signal recognition particle proteins

超分子名称: Signal recognition particle proteins / タイプ: complex / ID: 4 / 親要素: 1 / 含まれる分子: #2, #5-#6
由来(天然)生物種: Homo sapiens (ヒト)

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超分子 #5: Nascent chain preprolactin

超分子名称: Nascent chain preprolactin / タイプ: complex / ID: 5 / 親要素: 1 / 含まれる分子: #3
由来(天然)生物種: Homo sapiens (ヒト)

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超分子 #6: Isoform 2 of Transcription factor BTF3

超分子名称: Isoform 2 of Transcription factor BTF3 / タイプ: complex / ID: 6 / 親要素: 1 / 含まれる分子: #4
由来(天然)生物種: Homo sapiens (ヒト)

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分子 #1: SRP RNA 7SL

分子名称: SRP RNA 7SL / タイプ: rna / ID: 1 / コピー数: 1
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 54.095184 KDa
配列文字列:
CGCUAUGCCG AUCGGGUGUC CGCACUAAGU UCGGCAUCAA UAUGGUGACC UCCCGGGAGC GGGGGACCAC CAGGUUGCCU AAGGAGGGG UGAACCGGCC CAGGUCGGAA ACGGAGCAGG UCAAAACUCC CGUGCUGAUC AGUAGUGGGA UCGCGCCUGU G AAUAGCC

GENBANK: GENBANK: X04249.1

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分子 #9: 28S rRNA

分子名称: 28S rRNA / タイプ: rna / ID: 9 / コピー数: 1
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 1.539032 MDa
配列文字列: CGCGACCUCA GAUCAGACGU GGCGACCCGC UGAAUUUAAG CAUAUUAGUC AGCGGAGGAG AAGAAACUAA CCAGGAUUCC CUCAGUAAC GGCGAGUGAA CAGGGAAGAG CCCAGCGCCG AAUCCCCGCC CCGCGGCGGG GCGCGGGACA UGUGGCGUAC G GAAGACCC ...文字列:
CGCGACCUCA GAUCAGACGU GGCGACCCGC UGAAUUUAAG CAUAUUAGUC AGCGGAGGAG AAGAAACUAA CCAGGAUUCC CUCAGUAAC GGCGAGUGAA CAGGGAAGAG CCCAGCGCCG AAUCCCCGCC CCGCGGCGGG GCGCGGGACA UGUGGCGUAC G GAAGACCC GCUCCCCGGC GCCGCUCGUG GGGGGCCCAA GUCCUUCUGA UCGAGGCCCA GCCCGUGGAC GGUGUGAGGC CG GUAGCGG CCCCCGGCGC GCCGGGCCCG GGUCUUCCCG GAGUCGGGUU GCUUGGGAAU GCAGCCCAAA GCGGGUGGUA AAC UCCAUC UAAGGCUAAA UACCGGCACG AGACCGAUAG UCAACAAGUA CCGUAAGGGA AAGUUGAAAA GAACUUUGAA GAGA GAGUU CAAGAGGGCG UGAAACCGUU AAGAGGUAAA CGGGUGGGGU CCGCGCAGUC CGCCCGGAGG AUUCAACCCG GCGGC GGGU CCGGCCGUGU CGGCGGUCUC GGCGGAUCUU UCCCGCUCCC CGUUCCUCCC GACCCCUCCA CCCGCUCCCC CUCCCC CGC CGGUCUUCUC CCUUCACGGG GGGUGGGUCG GCGGGUGCGG GGGUGGGCGG GCGGGGCCGG GGGUGGGGUC GGCGGGG GA CCGUCCCCCG ACCGGCGACC GGCCGCCGCC GGGCGCAUUU CCACCGCGGC GGUGCGCCGC GACCGGCUCC GGGACGGC U GGGAAGGCCC GGCGGGGAAG GUGGCUCGGG GGGACGCCUC GCCGCCGUCG UCCGCGGCGG CGGCGGGCGC GACCCCUCC CCGAGUGUUA CAGCCCCCCC GGCAGCAGCA CUCGCCGAAU CCCGGGGCCG AGGGAGCGAG ACCCGUCGCC GCGCUCUCCC CCCUCCCGG CGCUCCCCCC CGCGGGGGUC CCCCGCGAGG GGGCUCCCCC CGCGGGGGCG CGCCGGUGUC GCCGCCCUCG C GGGCGCGG CACGGGGGGG CCGGGCCACC CCUCCCACGG CGCGACCGCU CUCCCGGCCC CCGCCGCCGC CUCUUCGGGC GU GCGGCGG GGGCGGGGCG GACUGUCCCC AGUGCGCCCC GGGCGGGUCG CGCCGUCGGG CCCGGGGGAG AAGUCGGCCA CGG GGCCAC GCGCGCCUCC GCGUCCCCCC CUCGCCGUCU CCGGGCGGCG GGGGGGGGUU UCGGCGCGGU GUUCUCGGCG CGCG CGCGC GAGCGAGCGC ACGGGGUCGG CGGCGACGUC GGCUACCCAC CCGACCCGUC UUGAAACACG GACCAAGGAG UCUAA CACG UGCGCGAGUC GGGGGCUCGC ACGAAAGCCG CCGUGGCGCA AUGAAGGUGA AGGCCGGCGC GCUCGCCGGC CGAGGU GGG AUCCCGAGGC CUCUCCAGUC CGCCGAGGGC GCACCACCGG CCCGUCUCGC CCGCCGCGCC GGGGAGGUGG AGCACGA GC GCACGUGUUA GGACCCGAAA GAUGGUGAAC UAUGCCUGGG CAGGGCGAAG CCAGAGGAAA CUCUGGUGGA GGUCCGUA G CGGUCCUGAC GUGCAAAUCG GUCGUCCGAC CUGGGUAUAG GGGCGAAAGA CUAAUCGAAC CAUCUAGUAG CUGGUUCCC UCCGAAGUUU CCCUCAGGAU AGCUGGCGCU CUCGCAACCA CGCAGUUUUA UCCGGUAAAG CGAAUGAUUA GAGGUCUUGG GGCCGAAAC GAUCUCAACC UAUUCUCAAA CUUUAAAUGG GUAAGAAGCC CGGCUCGCUG GCGUGAGCCG GGCGUGGAAU G CGAGUGCC UAGUGGGCCA CUUUUGGUAA GCAGAACUGG CGCUGCGGGA UGAACCGAAC GCCGGGUUAA GGCGCCCGAU GC CGACGCU CAUCAGACCC CAGAAAAGGU GUUGGUUGAU AUAGACAGCA GGACGGUGGC CAUGGAAGUC GGAAUCCGCU AAG GAGUGU GUAACAACUC ACCUGCCGAA UCAACUAGCC CUGAAAAUGG AUGGCGCUGG AGCGUCGGGC CCAUACCCGG CCGU CGCCG GCAGUCGAGA GUGGACGGGA GCGCGGGACU CCCCCCGCGG GGGUCCCCCG CCCCCGGAGC CCCGCGGACG CUACG CCGC GACGAGUAGG AGGGCCGCUG CGGUGAGCCU UGAAGCCUAG GGCGCGGGCC CGGGUGGAGC CGCCGCAGGU GCAGAU CUU GGUGGUAGUA GCAAAUAUUC AAACGAGAAC UUUGAAGGCC GAAGUGGAGA AGGGUUCCAU GUGAACAGCA GUUGAAC AU GGGUCAGUCG GUCCUGAGAG AUGGGCGAGC GCCGUUCCGA AGGGACGGGC GAUGGCCUCC GUUGCCCUCG GCCGAUCG A AAGGGAGUCG GGUUCAGAUC CCCGAAUCCG GAGUGGCGGA GAUGGGCGCC GCGAGGCGUC CAGUGCGGUA ACGCGACCG AUCCCGGAGA AGCCGGCGGG AGCCCCGGGG AGAGUUCUCU UUUCUUUGUG AAGGGCAGGG CGCCCUGGAA UGGGUUCGCC CCGAGAGAG GGGCCCGUGC CUUGGAAAGC GUCGCGGUUC CGGCGGCGUC CGGUGAGCUC UCGCUGGCCC UUGAAAAUCC G GGGGAGAG GGUGUAAAUC UCGCGCCGGG CCGUACCCAU AUCCGCAGCA GGUCUCCAAG GUGAACAGCC UCUGGCAUGU UG GAACAAU GUAGGUAAGG GAAGUCGGCA AGCCGGAUCC GUAACUUCGG GAUAAGGAUU GGCUCUAAGG GCUGGGUCGG UCG GGCUGG GGCGCGAAGC GGGGCUGGGC GCGCGCCGCG GCUGGACGAG GCGCCGCCGC CCCCCCCACG CCCGGGGCGC CCUC CCCCG GCCGGGUCCG CUCCCUCGCG CGCGCGUGCG CCGUGGCGCG CGCCGCGCGC GCGGCCGAGC CCCGUCUCCC UCCCC CCCU CUCCCCUCCC GGGGCGGGGU GCGGGGAGGG GCGGGCGGGG CCGUCGCUCG CCGCGCGUGC GCGUCGCUGC GCGUGC GCC GCGCGGGGGG UCCGGCGGGC CUCCGGACGG GGGCUCCGGG CACCCGGGCA CCCGGGGGGC CGGCGGCGGC GGCGACU CU GGACGCGAGC CGGGCCCUUC CCGUGGAUCG CCCCAGCUGC GGCGGGCGUC GCGGCCGCCC UCGGGGAGCC CGGCGGGC G CCGCGUGCGC GCGCGUGCGC GCCCGGGGUC GGGGGGGUGC GAGGCAGGGG AGGCCCUCUC UCCUCCUCCC CCACCCCGG CGCCGCGGCG CCGCGCGUGC GCGCGCGGUC UCCCCCCGCC GGGUCCGCCC CCGGGGCCGC GGUUCCGCGC GGCGCCUCGC CUCGGCCGG CGCCUAGCAG CCGACUUAGA ACUGGUGCGG ACCAGGGGAA UCCGACUGUU UAAUUAAAAC AAAGCAUCGC G AAGGCCCG CGGCGGGUGU UGACGCGAUG UGAUUUCUGC CCAGUGCUCU GAAUGUCAAA GUGAAGAAAU UCAAUGAAGC GC GGGUAAA CGGCGGGAGU AACUAUGACU CUCUUAAGGU AGCCAAAUGC CUCGUCAUCU AAUUAGUGAC GCGCAUGAAU GGA UGAACG AGAUUCCCAC UGUCCCUACC UACUAUCCAG CGAAACCACA GCCAAGGGAA CGGGCUUGGC GGAAUCAGCG GGGA AAGAA GACCCUGUUG AGCUUGACUC UAGUCUGGCA CGGUGAAGAG ACAUGAGAGG UGUAGAAUAA GUGGGAGGCC CCCGG CGCC CUCCCGCCCC CGCGAGGGGG CGGGGCGGGG UCCGCCGGCC UUGCGGGCCG CCGGUGAAAU ACCACUACUC UUAUCG UUU UUUCACUGAC CCGGUGAGGC GGGGGGGCGA GCCCCGAGGG GCUCUCGCUU CUGGCGCCAA GCGCCCGGCC GCGCGCC GG CCGGGCGCGA CCCGCUCCGG GGACAGUGCC AGGUGGGGAG UUUGACUGGG GCGGUACACC UGUCAAACGG UAACGCAG G UGUCCUAAGG CGAGCUCAGG GAGGACAGAA ACCUCCCGUG GAGCAGAAGG GCAAAAGCUC GCUUGAUCUU GAUUUUCAG UACGAAUACA GACCGUGAAA GCGGGGCCUC ACGAUCCUUC UGACCUUUUG GGUUUUAAGC AGGAGGUGUC AGAAAAGUUA CCACAGGGA UAACUGGCUU GUGGCGGCCA AGCGUUCAUA GCGACGUCGC UUUUUGAUCC UUCGAUGUCG GCUCUUCCUA U CAUUGUGA AGCAGAAUUC ACCAAGCGUU GGAUUGUUCA CCCACUAAUA GGGAACGUGA GCUGGGUUUA GACCGUCGUG AG ACAGGUU AGUUUUACCC UACUGAUGAU GUGUUGUUGC CAUGGUAAUC CUGCUCAGUA CGAGAGGAAC CGCAGGUUCA GAC AUUUGG UGUAUGUGCU UGGCUGAGGA GCCAAUGGGG CGAAGCUACC AUCUGUGGGA UUAUGACUGA ACGCCUCUAA GUCA GAAUC CCGCCCAGGC GGAACGAUAC GGCAGCGCCG CGGAGCCUCG GUUGGCCUCG GAUAGCCGGU CCCCCGCCGU CCCCG CCGG CGGCCCGCGU CGUGCGUCCG CCUCGGCGGC GUGCGGCGCG CCCCCCGCCG CGCGUCGGGA CCGGGGUCCG GUGCGG AGU GCCCUUCGUC CUGGGAAACG GGGCGCGGCC GGAGAGGCGG CCGCCCCCUC GCCCGUCACG CACGCCGUUC GUGGGGA AC CUGGCGCUAA ACCAUUCGUA GACGACCUGC UUCUGGGUCG GGGUUUCGUA CGUAGCAGAG CAGCUCCCUC GCUGCGAU C UAUUGAAAGU CAGCCCUCGA CACAAGGGUU UGU

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分子 #47: 5S ribosomal RNA

分子名称: 5S ribosomal RNA / タイプ: rna / ID: 47 / コピー数: 1
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 38.691914 KDa
配列文字列:
GUCUACGGCC AUACCACCCU GAACGCGCCC GAUCUCGUCU GAUCUCGGAA GCUAAGCAGG GUCGGGCCUG GUUAGUACUU GGAUGGGAG ACCGCCUGGG AAUACCGGGU GCUGUAGGCU U

GENBANK: GENBANK: 4CXE_4

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分子 #49: 5.8S ribosomal RNA

分子名称: 5.8S ribosomal RNA / タイプ: rna / ID: 49 / コピー数: 1
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 50.143648 KDa
配列文字列:
CGACUCUUAG CGGUGGAUCA CUCGGCUCGU GCGUCGAUGA AGAACGCAGC UAGCUGCGAG AAUUAAUGUG AAUUGCAGGA CACAUUGAU CAUCGACACU UCGAACGCAC UUGCGGCCCC GGGUUCCUCC CGGGGCUACG CCUGUCUGAG CGUCGCU

GENBANK: GENBANK: 4CXE_3

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分子 #2: Signal recognition particle 19 kDa protein

分子名称: Signal recognition particle 19 kDa protein / タイプ: protein_or_peptide / ID: 2 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 16.183746 KDa
組換発現生物種: Escherichia coli (大腸菌)
配列文字列:
MACAAARSPA DQDRFICIYP AYLNNKKTIA EGRRIPISKA VENPTATEIQ DVCSAVGLNV FLEKNKMYSR EWNRDVQYRG RVRVQLKQE DGSLCLVQFP SRKSVMLYAA EMIPKLKTRT QKTGGADQSL QQGEGSKKGK GKKKK

UniProtKB: Signal recognition particle 19 kDa protein

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分子 #3: Nascent chain preprolactin

分子名称: Nascent chain preprolactin / タイプ: protein_or_peptide / ID: 3 / 詳細: this will need to changed to UNK / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 9.549763 KDa
組換発現生物種: Oryctolagus cuniculus (ウサギ)
配列文字列: (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) ...文字列:
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)

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分子 #4: Isoform 2 of Transcription factor BTF3

分子名称: Isoform 2 of Transcription factor BTF3 / タイプ: protein_or_peptide / ID: 4 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 17.724037 KDa
組換発現生物種: Escherichia coli (大腸菌)
配列文字列:
MKETIMNQEK LAKLQAQVRI GGKGTARRKK KVVHRTATAD DKKLQFSLKK LGVNNISGIE EVNMFTNQGT VIHFNNPKVQ ASLAANTFT ITGHAETKQL TEMLPSILNQ LGADSLTSLR RLAEALPKQS VDGKAPLATG EDDDDEVPDL VENFDEASKN E AN

UniProtKB: Transcription factor BTF3

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分子 #5: Signal recognition particle subunit SRP68

分子名称: Signal recognition particle subunit SRP68 / タイプ: protein_or_peptide / ID: 5 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 70.831578 KDa
組換発現生物種: Escherichia coli (大腸菌)
配列文字列: MAAEKQVPGG GGGGGSGGGG GSGGGGSGGG RGAGGEENKE NERPSAGSKA NKEFGDSLSL EILQIIKESQ QQHGLRHGDF QRYRGYCSR RQRRLRKTLN FKMGNRHKFT GKKVTEELLT DNRYLLLVLM DAERAWSYAM QLKQEANTEP RKRFHLLSRL R KAVKHAEE ...文字列:
MAAEKQVPGG GGGGGSGGGG GSGGGGSGGG RGAGGEENKE NERPSAGSKA NKEFGDSLSL EILQIIKESQ QQHGLRHGDF QRYRGYCSR RQRRLRKTLN FKMGNRHKFT GKKVTEELLT DNRYLLLVLM DAERAWSYAM QLKQEANTEP RKRFHLLSRL R KAVKHAEE LERLCESNRV DAKTKLEAQA YTAYLSGMLR FEHQEWKAAI EAFNKCKTIY EKLASAFTEE QAVLYNQRVE EI SPNIRYC AYNIGDQSAI NELMQMRLRS GGTEGLLAEK LEALITQTRA KQAATMSEVE WRGRTVPVKI DKVRIFLLGL ADN EAAIVQ AESEETKERL FESMLSECRD AIQVVREELK PDQKQRDYIL EGEPGKVSNL QYLHSYLTYI KLSTAIKRNE NMAK GLQRA LLQQQPEDDS KRSPRPQDLI RLYDIILQNL VELLQLPGLE EDKAFQKEIG LKTLVFKAYR CFFIAQSYVL VKKWS EALV LYDRVLKYAN EVNSDAGAFK NSLKDLPDVQ ELITQVRSEK CSLQAAAILD ANDAHQTETS SSQVKDNKPL VERFET FCL DPSLVTKQAN LVHFPPGFQP IPCKPLFFDL ALNHVAFPPL EDKLEQKTKS GLTGYIKGIF GFRS

UniProtKB: Signal recognition particle subunit SRP68

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分子 #6: Signal recognition particle 54 kDa protein

分子名称: Signal recognition particle 54 kDa protein / タイプ: protein_or_peptide / ID: 6 / 詳細: mutant G226E / コピー数: 1 / 光学異性体: LEVO
EC番号: 加水分解酵素; 酸無水物に作用; GTPに作用・細胞または細胞小器官の運動に関与
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 55.847734 KDa
組換発現生物種: Escherichia coli (大腸菌)
配列文字列: MVLADLGRKI TSALRSLSNA TIINEEVLNA MLKEVCTALL EADVNIKLVK QLRENVKSAI DLEEMASGLN KRKMIQHAVF KELVKLVDP GVKAWTPTKG KQNVIMFVGL QGSGKTTTCS KLAYYYQRKG WKTCLICADT FRAGAFDQLK QNATKARIPF Y GSYTEMDP ...文字列:
MVLADLGRKI TSALRSLSNA TIINEEVLNA MLKEVCTALL EADVNIKLVK QLRENVKSAI DLEEMASGLN KRKMIQHAVF KELVKLVDP GVKAWTPTKG KQNVIMFVGL QGSGKTTTCS KLAYYYQRKG WKTCLICADT FRAGAFDQLK QNATKARIPF Y GSYTEMDP VIIASEGVEK FKNENFEIII VDTSGRHKQE DSLFEEMLQV ANAIQPDNIV YVMDASIEQA CEAQAKAFKD KV DVASVIV TKLDGHAKGG GALSAVAATK SPIIFIGTGE HIDDFEPFKT QPFISKLLGM GDIEGLIDKV NELKLDDNEA LIE KLKHGQ FTLRDMYEQF QNIMKMGPFS QILGMIPGFG TDFMSKGNEQ ESMARLKKLM TIMDSMNDQE LDSTDGAKVF SKQP GRIQR VARGSGVSTR DVQELLTQYT KFAQMVKKMG GIKGLFKGGD MSKNVSQSQM AKLNQQMAKM MDPRVLHHMG GMAGL QSMM RQFQQGAAGN MKGMMGFNNM

UniProtKB: Signal recognition particle subunit SRP54

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分子 #7: L8

分子名称: L8 / タイプ: protein_or_peptide / ID: 7 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 26.570105 KDa
配列文字列: GRVIRGQRKG AGSVFRAHVK HRKGAARLRA VDFAERHGYI KGIVKDIIHD PGRGAPLAKV VFRDPYRFKK RTELFIAAEG IHTGQFVYC GKKAQLNIGN VLPVGTMPEG TIVCCLEEKP GDRGKLARAS GNYATVISHN PETKKTRVKL PSGSKKVISS A NRAVVGVV ...文字列:
GRVIRGQRKG AGSVFRAHVK HRKGAARLRA VDFAERHGYI KGIVKDIIHD PGRGAPLAKV VFRDPYRFKK RTELFIAAEG IHTGQFVYC GKKAQLNIGN VLPVGTMPEG TIVCCLEEKP GDRGKLARAS GNYATVISHN PETKKTRVKL PSGSKKVISS A NRAVVGVV AGGGRIDKPI LKAGRAYHKY KAKRNCWPRV RGVAMNPVEH PFGGGNHQHI GKPSTIRRDA PAGRKVGLIA AR RTGR

UniProtKB: Large ribosomal subunit protein uL2

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分子 #8: 60S ribosomal protein L29

分子名称: 60S ribosomal protein L29 / タイプ: protein_or_peptide / ID: 8 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 24.608236 KDa
配列文字列: MAKSKNHTTH NQSRKWHRNG IKKPRSQRYE SLKGVDPKFL RNMRFAKKHN KKGLKKMQAN NAKAMAARAE AIKALVKPKE VKPTIPKGV SRKLDRLAYI AHPKLGRRAR ARIARGLRLS RPQTKAKAKT EPQIKGKVKA QIKAQAQAQI KSKGKGKAQA E TKPKAQAQ ...文字列:
MAKSKNHTTH NQSRKWHRNG IKKPRSQRYE SLKGVDPKFL RNMRFAKKHN KKGLKKMQAN NAKAMAARAE AIKALVKPKE VKPTIPKGV SRKLDRLAYI AHPKLGRRAR ARIARGLRLS RPQTKAKAKT EPQIKGKVKA QIKAQAQAQI KSKGKGKAQA E TKPKAQAQ AKPKAQAQGK PKAQAQAKPK AHAQAKPKAQ AQAKPKAQAQ TKRTGVTPGL LSAWG

UniProtKB: Large ribosomal subunit protein eL29

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分子 #10: uL3

分子名称: uL3 / タイプ: protein_or_peptide / ID: 10 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 46.107977 KDa
組換発現生物種: Escherichia coli (大腸菌)
配列文字列: MSHRKFSAPR HGSLGFLPRK RSSRHRGKVK SFPKDDPSKP VHLTAFLGYK AGMTHIVREV DRPGSKVNKK EVVEAVTIVE TPPMVVVGI VGYVETPRGL RTFKTVFAEH ISDECKRRFY KNWHKSKKKA FTKYCKKWQD DAGKRQLDKD FSSMKKYCQV I RVLAHTQM ...文字列:
MSHRKFSAPR HGSLGFLPRK RSSRHRGKVK SFPKDDPSKP VHLTAFLGYK AGMTHIVREV DRPGSKVNKK EVVEAVTIVE TPPMVVVGI VGYVETPRGL RTFKTVFAEH ISDECKRRFY KNWHKSKKKA FTKYCKKWQD DAGKRQLDKD FSSMKKYCQV I RVLAHTQM RLLPLRQKKA HLMEIQVNGG TVAEKLDWAR ERLEQQVPVS QVFGQDEMID VIGVTKGKGY KGVTSRWHTK KL PRKTHRG LRKVACIGAW HPARVAFSVA RAGQKGYHHR TEINKKIYKI GQGYLIKDGK LIKNNASTDY DLSDKSINPL GGF VHYGEV TNDFVMLKGC VVGTKKRVLT LRKSLLVQTK RRALEKIDLK FIDTTSKFGH GRFQTVEEKK AFMGPLKKDR IAKE EGA

UniProtKB: Large ribosomal subunit protein uL3

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分子 #11: 60S ribosomal protein L30

分子名称: 60S ribosomal protein L30 / タイプ: protein_or_peptide / ID: 11 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 12.821092 KDa
配列文字列:
MVAAKKTKKS LESINSRLQL VMKSGKYVLG YKQTLKMIRQ GKAKLVILAN NCPALRKSEI EYYAMLAKTG VHHYSGNNIE LGTACGKYY RVCTLSIIDP GDSDIIRSMP EQTGEK

UniProtKB: Large ribosomal subunit protein eL30

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分子 #12: 60S ribosomal protein L4

分子名称: 60S ribosomal protein L4 / タイプ: protein_or_peptide / ID: 12 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 46.388855 KDa
配列文字列: MACARPLISV YSEKGESSGK NVTLPAVFKA PIRPDIVNFV HTNLRKNNRQ PYAVSELAGH QTSAESWGTG RAVARIPRVR GGGTHRSGQ GAFGNMCRGG RMFAPTKTWR RWHRRVNTTQ KRYAICSALA ASALPALVMS KGHRIEEVPE LPLVVEDKVE G YKKTKEAV ...文字列:
MACARPLISV YSEKGESSGK NVTLPAVFKA PIRPDIVNFV HTNLRKNNRQ PYAVSELAGH QTSAESWGTG RAVARIPRVR GGGTHRSGQ GAFGNMCRGG RMFAPTKTWR RWHRRVNTTQ KRYAICSALA ASALPALVMS KGHRIEEVPE LPLVVEDKVE G YKKTKEAV LLLKKLKAWN DIKKVYASQR MRAGKGKMRN RRRIQRRGPC VIYNEDNGIV KAFRNIPGIT LLNVTKLNIL KL APGGHVG RFCIWTESAF RKLDDLYGTW RKAASLKSNY NLPMHKMLNT DLSRILKSPE IQRALRAPRK KIHRRVLKKN PLK NLRIML KLNPYAKTMR RNTILRQARN HKLRVERAAA ALAAKSDPKE APAKKKPVVG KKKKPVVGRK AAAAKKPAAD KKAA DKRAG PEDKKPAA

UniProtKB: Large ribosomal subunit protein uL4

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分子 #13: Ribosomal protein L31

分子名称: Ribosomal protein L31 / タイプ: protein_or_peptide / ID: 13 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 14.494938 KDa
配列文字列:
MAPAKKGGEK KKGRSAINEV VTREYTINIH KRIHGVGFKK RAPRALKEIR KFAMKEMGTP DVRIDTRLNK AVWAKGIRNV PYRIRVRLS RKRNEDEDSP NKLYTLVTYV PVTTFKNLQT VNVDEN

UniProtKB: Large ribosomal subunit protein eL31

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分子 #14: Ribosomal_L18_c domain-containing protein

分子名称: Ribosomal_L18_c domain-containing protein / タイプ: protein_or_peptide / ID: 14 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 34.481828 KDa
配列文字列: MGFVKVVKNK AYFKRYQVKF RRRREGKTDY YARKRLVIQD KNKYNTPKYR MIVRVTNRDI ICQIAYARIE GDMIVCAAYA HELPKYGVK VGLTNYAAAY CTGLLLARRL LNRFGMDKIY EGQVEVTGDE YNVESIDGQP GAFTCYLDAG LARTTTGNKV F GALKGAVD ...文字列:
MGFVKVVKNK AYFKRYQVKF RRRREGKTDY YARKRLVIQD KNKYNTPKYR MIVRVTNRDI ICQIAYARIE GDMIVCAAYA HELPKYGVK VGLTNYAAAY CTGLLLARRL LNRFGMDKIY EGQVEVTGDE YNVESIDGQP GAFTCYLDAG LARTTTGNKV F GALKGAVD GGLSIPHSTK RFPGYDSESK EFNAEVHRKH IMGQNVADYM RYLMEEDEDA YKKQFSQYIK NNVTPDMMEE MY KKAHAAI RENPVYEKKP KREVKKKRWN RPKMSLAQKK DRVAQKKASF LRAQERAAES

UniProtKB: Large ribosomal subunit protein uL18

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分子 #15: Ribosomal protein L32

分子名称: Ribosomal protein L32 / タイプ: protein_or_peptide / ID: 15 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 18.350049 KDa
配列文字列:
MCLLLISFLY LKEKKGCPLL GTIAALRPLV KPKIVKKRTK KFIRHQSDRY VKIKRNWRKP RGIDNRVRRR FKGQILMPNI GYGSNKKTK HMLPSGFRKF LVHNVKELEV LLMCNKSYCA EIAHNVSSKN RKAIVERAAQ LAIRVTNPNA RLRSEENE

UniProtKB: Large ribosomal subunit protein eL32

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分子 #16: 60S ribosomal protein L6

分子名称: 60S ribosomal protein L6 / タイプ: protein_or_peptide / ID: 16 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 33.055297 KDa
配列文字列: MAGEKAPAAK PDATKKSPAK KADHARGKAK KKTLAEKKPK KGKPHCSRNP VLVRGIGRYS RSAMYSRKAL YKRKYAAPKS RIERKKKRE KVLATVTKPV GGDKNGGTRV VKLRKMPRYY PTEDVPRKLL SHGRKPFSQH VRKLRASITP GTILIILTGR H RGKRVVFL ...文字列:
MAGEKAPAAK PDATKKSPAK KADHARGKAK KKTLAEKKPK KGKPHCSRNP VLVRGIGRYS RSAMYSRKAL YKRKYAAPKS RIERKKKRE KVLATVTKPV GGDKNGGTRV VKLRKMPRYY PTEDVPRKLL SHGRKPFSQH VRKLRASITP GTILIILTGR H RGKRVVFL KQLSSGLLLV TGPLSLNRVP LRRTHQKFVI ATSTKIDISG VKIPKHLTDA YFKKKQLRKP RHQEGEIFDT EK EKYEITE QRKVDQKAVD SQILPKIKAV PQLQGYLRSV FALTNGVYPH KLVF

UniProtKB: Large ribosomal subunit protein eL6

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分子 #17: 60S ribosomal protein L35a

分子名称: 60S ribosomal protein L35a / タイプ: protein_or_peptide / ID: 17 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 12.580809 KDa
配列文字列:
MSGRLWCKAI FAGYKRGLRN QREHTALLKI EGVYARDETE FYLGKRCAYV YKAKNNTVTP GGKPNKTRVI WGKVTRAHGN SGMVRAKFR SNLPAKAIGH RIRVMLYPSR I

UniProtKB: Large ribosomal subunit protein eL33

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分子 #18: uL30

分子名称: uL30 / タイプ: protein_or_peptide / ID: 18 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 26.662787 KDa
配列文字列: NFAELKIKRL RKKFAQKMLR KARRKLIYEK AKHYHKEYRQ MYRTEIRMAR MARKAGNFYV PAEPKLAFVI RIRGINGVSP KVRKVLQLL RLRQIFNGTF VKLNKASINM LRIVEPYIAW GYPNLKSVNE LIYKRGYGKI NKKRIALTDN ALIARSLGKY G IICMEDLI ...文字列:
NFAELKIKRL RKKFAQKMLR KARRKLIYEK AKHYHKEYRQ MYRTEIRMAR MARKAGNFYV PAEPKLAFVI RIRGINGVSP KVRKVLQLL RLRQIFNGTF VKLNKASINM LRIVEPYIAW GYPNLKSVNE LIYKRGYGKI NKKRIALTDN ALIARSLGKY G IICMEDLI HEIYTVGKRF KEANNFLWPF KLSSPRGGMK KKTTHFVEGE DAGNREDQIN RLIRRMN

UniProtKB: Large ribosomal subunit protein uL30

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分子 #19: 60S ribosomal protein L34

分子名称: 60S ribosomal protein L34 / タイプ: protein_or_peptide / ID: 19 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 14.557543 KDa
配列文字列:
MSLPGRCLEA ATMVQRLTYR RRLSYNTASN KTRLSRTPGN RIVYLYTKKV GKAPKSACGV CPGRLRGVRA VRPKVLMRLS KTKKHVSRA YGGSMCAKCV RDRIKRAFLI EEQKIVVKVL KAQAQSQKAK

UniProtKB: Large ribosomal subunit protein eL34

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分子 #20: 60S ribosomal protein L7a

分子名称: 60S ribosomal protein L7a / タイプ: protein_or_peptide / ID: 20 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 36.267605 KDa
配列文字列: MSSYRLGYCM KEERHNLVLC LWSQSPGILN SKCLWPFTNI HLLVGALPRE GAGGAWGGGR SEQLPTCSTT HHDFTWDKKV VNPLFEKRP KNFGIGQDIQ PKRDLTRFVK WPRYIRLQRQ RAILYKRLKV PPAINQFTQV LDRQTATQLL KLAHKYRPET K QEKKQRLL ...文字列:
MSSYRLGYCM KEERHNLVLC LWSQSPGILN SKCLWPFTNI HLLVGALPRE GAGGAWGGGR SEQLPTCSTT HHDFTWDKKV VNPLFEKRP KNFGIGQDIQ PKRDLTRFVK WPRYIRLQRQ RAILYKRLKV PPAINQFTQV LDRQTATQLL KLAHKYRPET K QEKKQRLL ARAEKKAAGK GDVPTKRPPV LRAGVNTVTT LVENKKAQLV VIAHDVDPIE LVVFLPALCR KMGVPYCILK GK ARLCRLV HRKTCTTVAF TQVNSEDKGA LAKLVEAIRT NYNDRYDEIR RHWGGNVLGP KSVARIAKLE KAKAKELATK LG

UniProtKB: Large ribosomal subunit protein eL8

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分子 #21: 60S ribosomal protein L35

分子名称: 60S ribosomal protein L35 / タイプ: protein_or_peptide / ID: 21 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 14.566599 KDa
配列文字列:
MAKIKARDLR GKKKEELLKQ LDDLKVELSQ LRVAKVTGGA ASKLSKIRVV RKSIARVLTV INQTQKENLR KFYKGKKYKP LDLRPKKTR AMRRRLNKHE ESLKTKKQQR KERLYPLRKY AVKA

UniProtKB: Large ribosomal subunit protein uL29

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分子 #22: 60S ribosomal protein L9

分子名称: 60S ribosomal protein L9 / タイプ: protein_or_peptide / ID: 22 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 21.871418 KDa
配列文字列: MKTILSNQTV DIPENVDISL KGRTVIVKGP RGTLRRDFNH INVELSLLGK KKKRLRVDKW WGNRKELATV RTICSHVQNM IKGVTLGFR YKMRSVYAHF PINVVIQENG SLVEIRNFLG EKYIRRVRMR PGVACSVSQA QKDELVLEGN DIELVSNSAA L IQQATTVK ...文字列:
MKTILSNQTV DIPENVDISL KGRTVIVKGP RGTLRRDFNH INVELSLLGK KKKRLRVDKW WGNRKELATV RTICSHVQNM IKGVTLGFR YKMRSVYAHF PINVVIQENG SLVEIRNFLG EKYIRRVRMR PGVACSVSQA QKDELVLEGN DIELVSNSAA L IQQATTVK NKDIRKFLDG IYVSEKGTVQ QADE

UniProtKB: Large ribosomal subunit protein uL6

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分子 #23: 60S ribosomal protein L36

分子名称: 60S ribosomal protein L36 / タイプ: protein_or_peptide / ID: 23 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 11.888371 KDa
配列文字列:
ALRYPMAVGL NKGHKVTKNV SKPRHSRRRG RLTKHTKFVR DMIREVCGFA PYERRAMELL KVSKDKRALK FIKKRVGTHI RAKRKREEL SSVLAAMRKA AAK

UniProtKB: Large ribosomal subunit protein eL36

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分子 #24: 60S ribosomal protein L10

分子名称: 60S ribosomal protein L10 / タイプ: protein_or_peptide / ID: 24 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 24.643057 KDa
配列文字列: MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG HMVSDEYEQL SSEALEAARI CANKYMVKSC GKDGFHIRV RLHPFHVIRI NKMLSCAGAD RLQTGMRGAF GKPQGTVARV HIGQVIMSIR TKLQNKEHVV EALRRAKFKF P GRQKIHIS ...文字列:
MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG HMVSDEYEQL SSEALEAARI CANKYMVKSC GKDGFHIRV RLHPFHVIRI NKMLSCAGAD RLQTGMRGAF GKPQGTVARV HIGQVIMSIR TKLQNKEHVV EALRRAKFKF P GRQKIHIS KKWGFTKFNA DEFEDMVAEK RLIPDGCGVK YIPNRGPLDK WRALHS

UniProtKB: Large ribosomal subunit protein uL16

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分子 #25: Ribosomal protein L37

分子名称: Ribosomal protein L37 / タイプ: protein_or_peptide / ID: 25 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 11.111032 KDa
配列文字列:
MTKGTSSFGK RRNKTHTLCR RCGSKAYHLQ KSTCGKCGYP AKRKRKYNWS AKAKRRNTTG TGRMRHLKIV YRRFRHGFRE GTTPKPKRA AVAASSSS

UniProtKB: Large ribosomal subunit protein eL37

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分子 #26: Ribosomal protein L11

分子名称: Ribosomal protein L11 / タイプ: protein_or_peptide / ID: 26 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 20.288465 KDa
配列文字列:
MAQDQGEKEN PMRELRIRKL CLNICVGESG DRLTRAAKVL EQLTGQTPVF SKARYTVRSF GIRRNEKIAV HCTVRGAKAE EILEKGLKV REYELRKNNF SDTGNFGFGI QEHIDLGIKY DPSIGIYGLD FYVVLGRPGF SIADKKRRTG CIGAKHRISK E EAMRWFQQ KYDGIILPGK

UniProtKB: Large ribosomal subunit protein uL5

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分子 #27: 60S ribosomal protein L38

分子名称: 60S ribosomal protein L38 / タイプ: protein_or_peptide / ID: 27 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 8.107752 KDa
配列文字列:
PRKIEEIKDF LLTARRKDAK SVKIKKNKDN VKFKVRCSRY LYTLVITDKE KAEKLKQSLP PGLAVKELK

UniProtKB: Large ribosomal subunit protein eL38

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分子 #28: 60S ribosomal protein L13

分子名称: 60S ribosomal protein L13 / タイプ: protein_or_peptide / ID: 28
詳細: APSRNGMILKPHFHKDWQRRVATWFNQPARKIRRRKARQARARRIAPRPASGPLRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKVARTIGISVDPR RRNKSTESLQANVQRLKEYRSKLVLFPRKPSAPKKGDSSAEELKLATQLTGPVMPIRNVFKKEKARVITEEEKNFKAFASLRMARANARLFGIRAKRAKE AAEQDVEKKK
コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 24.216525 KDa
配列文字列: APSRNGMILK PHFHKDWQRR VATWFNQPAR KIRRRKARQA RARRIAPRPA SGPLRPIVRC PTVRYHTKVR AGRGFSLEEL RVAGIHKKV ARTIGISVDP RRRNKSTESL QANVQRLKEY RSKLVLFPRK PSAPKKGDSS AEELKLATQL TGPVMPIRNV F KKEKARVI ...文字列:
APSRNGMILK PHFHKDWQRR VATWFNQPAR KIRRRKARQA RARRIAPRPA SGPLRPIVRC PTVRYHTKVR AGRGFSLEEL RVAGIHKKV ARTIGISVDP RRRNKSTESL QANVQRLKEY RSKLVLFPRK PSAPKKGDSS AEELKLATQL TGPVMPIRNV F KKEKARVI TEEEKNFKAF ASLRMARANA RLFGIRAKRA KEAAEQDVEK KK

UniProtKB: Uncharacterized protein

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分子 #29: Ribosomal protein L39

分子名称: Ribosomal protein L39 / タイプ: protein_or_peptide / ID: 29 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 6.426759 KDa
配列文字列:
MSSHKTFRIK RFLAKKQKQN RPIPQWIRMK TGNKIRYNSK RRHWRRTKLG L

UniProtKB: Large ribosomal subunit protein eL39

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分子 #30: 60S ribosomal protein L14

分子名称: 60S ribosomal protein L14 / タイプ: protein_or_peptide / ID: 30 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 23.810432 KDa
配列文字列: AVFRRFVEVG RVAYVSFGPH AGKLVAIVDV IDQNRALVDG PCTRVRRQAM PFKCMQLTDF ILKFPHSARQ KYVRKAWEKA DINTKWAAT RWAKKIEARE RKAKMTDFDR YKVMKAKKMR NRIIKNEVKK LQRAALLKAS PKKAPVAKGA VAAAAAAAKV P AKKATAAG ...文字列:
AVFRRFVEVG RVAYVSFGPH AGKLVAIVDV IDQNRALVDG PCTRVRRQAM PFKCMQLTDF ILKFPHSARQ KYVRKAWEKA DINTKWAAT RWAKKIEARE RKAKMTDFDR YKVMKAKKMR NRIIKNEVKK LQRAALLKAS PKKAPVAKGA VAAAAAAAKV P AKKATAAG KKAAAQKAPA QKAPAQKAAG QKAAQPPKAQ KGQKPPAQKA PAPKASGKKA

UniProtKB: Large ribosomal subunit protein eL14

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分子 #31: Ubiquitin A-52 residue ribosomal protein fusion product 1

分子名称: Ubiquitin A-52 residue ribosomal protein fusion product 1
タイプ: protein_or_peptide / ID: 31 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 14.758394 KDa
配列文字列:
MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN IQKESTLHLV LRLRGGIIEP SLRQLAQKY NCDKMICRKC YARLHPRAVN CRKKKCGHTN NLRPKKKVK

UniProtKB: Ubiquitin-ribosomal protein eL40 fusion protein

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分子 #32: Ribosomal protein L15

分子名称: Ribosomal protein L15 / タイプ: protein_or_peptide / ID: 32 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 24.207285 KDa
配列文字列: MGAYKYIQEL WRKKQSDVMR FLLRVRCWQY RQLSALHRAP RPTRPDKARR LGYKAKQGYV IYRIRVRRGG RKRPVPKGAT YGKPVHHGV NQLKFARSLQ SVAEERAGRH CGALRVLNSY WVGEDSTYKF FEVILIDPFH KAIRRNPDTQ WITKPVHKHR E MRGLTSAG ...文字列:
MGAYKYIQEL WRKKQSDVMR FLLRVRCWQY RQLSALHRAP RPTRPDKARR LGYKAKQGYV IYRIRVRRGG RKRPVPKGAT YGKPVHHGV NQLKFARSLQ SVAEERAGRH CGALRVLNSY WVGEDSTYKF FEVILIDPFH KAIRRNPDTQ WITKPVHKHR E MRGLTSAG RKSRGLGKGH KFHHTIGGSR RAAWRRRNTL QLHRYR

UniProtKB: Large ribosomal subunit protein eL15

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分子 #33: 60s ribosomal protein l41

分子名称: 60s ribosomal protein l41 / タイプ: protein_or_peptide / ID: 33 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 3.473451 KDa
配列文字列:
MRAKWRKKRM RRLKRKRRKM RQRSK

UniProtKB: Small ribosomal subunit protein eS32

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分子 #34: 60S ribosomal protein L13a

分子名称: 60S ribosomal protein L13a / タイプ: protein_or_peptide / ID: 34 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 56.501578 KDa
配列文字列: MVVPAPAWSP TTSLLLLLLL LLLSPGLLGS PDCSFPHSPI SSTFANTIRQ LSDYLLQDYP VTVASNLQDD ELCGAFWRLV LAQRWMGQL KTVAGSQMQK LLEAVNTEIV FVTSCALQPL PSCLRFVQAN ISHLLQDTSQ QLVALKPWIT RRNFSRCLEL Q CQPDPSTL ...文字列:
MVVPAPAWSP TTSLLLLLLL LLLSPGLLGS PDCSFPHSPI SSTFANTIRQ LSDYLLQDYP VTVASNLQDD ELCGAFWRLV LAQRWMGQL KTVAGSQMQK LLEAVNTEIV FVTSCALQPL PSCLRFVQAN ISHLLQDTSQ QLVALKPWIT RRNFSRCLEL Q CQPDPSTL LPPRSPGALE ATSLPAPQAS LLLLLLLLLL PAALLLLATA WCLRRRRRRR RMPCPGERPW TPRSDGNDTD WS ARRRPAL QWGLSAHALD TLANEKTGNG LCCVTSSAPV SRDKKPCAKS SFFPRQLPKM AEGQQVLVLD GRGHLLGRLA AIV AKQVLL GRKVVVVRCE GINISGNFYR NKLKYLAFLR KRMNTNPSRG PYHFRAPSRI FWRTVRGMLP HKTKRGQAAL DRLK VFDGI PPPYDKKKRM VVPAALKVVR LKPTRKFAYL GRLAHEVGWK YQAVTATLEE KRKEKAKIHY RKKKQLMRLR KQAEK NVEK KIDRFTEVLK THGFLV

UniProtKB: Fms related receptor tyrosine kinase 3 ligand

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分子 #35: eL42

分子名称: eL42 / タイプ: protein_or_peptide / ID: 35 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 16.130169 KDa
配列文字列:
MVAPIASHEE VRLGTAYILP LQAGSLSFRA DSVPAMVNVP KTRRTFCKKC GKHQPHKVTQ YKKGKDSLYA QGKRRYDRKQ SGYGGQTKP IFRKKAKTTK KIVLRLECVE PNCRSKRMLA IKRCKHFELG GDKKRKGQVI QF

UniProtKB: Ribosomal protein L36a

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分子 #36: 60S ribosomal protein L17

分子名称: 60S ribosomal protein L17 / タイプ: protein_or_peptide / ID: 36 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 17.758678 KDa
配列文字列:
VRYSLDPENP TKSCKSRGSN LRVHFKNTRE TAQAIKGMHI RKATKYLKDV TLKKQCVPFR RYNGGVGRCA QAKQWGWTQG RWPKKSAEF LLHMLKNAES NAELKGLDVD SLVIEHIQVN KAPKMRRRTY RAHGRINPYM SSPCHIEMIL TEKE

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分子 #37: eL43

分子名称: eL43 / タイプ: protein_or_peptide / ID: 37 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 10.29935 KDa
配列文字列:
MAKRTKKVGI VGKYGTRYGA SLRKMVKKIE ISQHAKYTCS FCGKTKMKRR AVGIWHCGSC MKTVAGGAWT YNTTSAVTVK SAIRRLKEL KDQ

UniProtKB: Large ribosomal subunit protein eL43

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分子 #38: eL18

分子名称: eL18 / タイプ: protein_or_peptide / ID: 38 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 21.457391 KDa
配列文字列:
GVDIRHNKDR KVRRKEPKSQ DIYLRLLVKL YRFLARRTNS TFNQVVLKRL FMSRTNRPPL SLSRMIRKMK LPGREGKTAV VVGTITDDV RVQEVPKLKV CALRVSSRAR SRILKAGGKI LTFDQLALDS PKGCGTVLLS GPRKGREVYR HFGKAPGTPH S HTKPYVRS KGRKFERARG RRASRGYKN

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分子 #39: 60S ribosomal protein L28

分子名称: 60S ribosomal protein L28 / タイプ: protein_or_peptide / ID: 39 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 15.783614 KDa
配列文字列:
MSAHLQWMVV RNCSSFLIKR NKQTYSTEPN NLKARNSFRY NGLIHRKTVG VEPAADGKGV VVVMKRRSGQ RKPATSYVRT TINKNARAT LSSIRHMIRK NKYHPDLRMA AIRRASAILR SQKPVMVKRK RTRPTKSS

UniProtKB: Large ribosomal subunit protein eL28

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分子 #40: 60S ribosomal protein L19

分子名称: 60S ribosomal protein L19 / タイプ: protein_or_peptide / ID: 40 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 23.535281 KDa
配列文字列: MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLIKDGLI IRKPVTVHSR ARCRKNTLAR RKGRHMGIGK RKGTANARM PEKVTWMRRM RILRRLLRRY RESKKIDRHM YHSLYLKVKG NVFKNKRILM EHIHKLKADK ARKKLLADQA E ARRSKTKE ...文字列:
MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLIKDGLI IRKPVTVHSR ARCRKNTLAR RKGRHMGIGK RKGTANARM PEKVTWMRRM RILRRLLRRY RESKKIDRHM YHSLYLKVKG NVFKNKRILM EHIHKLKADK ARKKLLADQA E ARRSKTKE ARKRREERLQ AKKEEIIKTL SKEEETKK

UniProtKB: Large ribosomal subunit protein eL19

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分子 #41: 60S ribosomal protein L18a

分子名称: 60S ribosomal protein L18a / タイプ: protein_or_peptide / ID: 41 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 20.696363 KDa
配列文字列:
KASGTLREYK VVGRCLPTPK CRTPPLYRMR IFAPNHVVAK SRFWYFVSQL KKMKKSSGEI VYCGQVFEKS PLRVKNFGIW LRYDSRSGT HNMYREYRDL TTAGAVTQCY RDMGARHRAR AHSIQIMKVE EIAASKCRRP AVKQFHDSKI KFPLPHRVLR R QHKPRFTT KRPNTFF

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分子 #42: 60S ribosomal protein L21

分子名称: 60S ribosomal protein L21 / タイプ: protein_or_peptide / ID: 42 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 18.609988 KDa
配列文字列:
MTNTKGKRRG TRYMFSRPFR KHGVVPLATY MRIYKKGDIV DIKGMGTVQK GMPHKCYHGK TGRVYNVTQH AVGIVVNKQV KGKILAKRI NVRIEHIKHS KSRDSFLKRV KENDQKKKEA KEKGTWVQLK RQPAPPREAH FVRTNGKEPE LLEPIPYEFM A

UniProtKB: Large ribosomal subunit protein eL21

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分子 #43: Ribosomal protein L22

分子名称: Ribosomal protein L22 / タイプ: protein_or_peptide / ID: 43 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 11.836638 KDa
配列文字列:
QVLKFTLDCT HPVEDGIMDA ANFEQFLQER IKVNGKAGNL GGGVVTIERS KSKITVTSEV PFSKRYLKYL TKKYLKKNNL RDWLRVVAN SKESYELRYF QIN

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分子 #44: Ribosomal protein L23

分子名称: Ribosomal protein L23 / タイプ: protein_or_peptide / ID: 44 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 14.892505 KDa
配列文字列:
MSKRGRGGSS GAKFRISLGL PVGAVINCAD NTGAKNLYII SVKGIKGRLN RLPAAGVGDM VMATVKKGKP ELRKKVHPAV VIRQRKSYR RKDGVFLYFE DNAGVIVNNK GEMKGSAITG PVAKECADLW PRIASNAGSI A

UniProtKB: Large ribosomal subunit protein uL14

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分子 #45: Ribosomal protein L24

分子名称: Ribosomal protein L24 / タイプ: protein_or_peptide / ID: 45 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 17.825111 KDa
配列文字列:
MKVELCSFSG YKIYPGHGRR YARTDGKVFQ FLNAKCESAF LSKRNPRQIN WTVLYRRKHK KGQSEEIQKK RTRRAVKFQR AITGASLAD IMAKRNQKPE VRKAQREQAI RAAKEAKKAK QASKKTAMAA AKAPTKAAPK QKIVKPVKVS APRVGGKR

UniProtKB: Large ribosomal subunit protein eL24

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分子 #46: Ribosomal_L23eN domain-containing protein

分子名称: Ribosomal_L23eN domain-containing protein / タイプ: protein_or_peptide / ID: 46 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 17.768246 KDa
配列文字列:
MAPKAKKEAP APPKVEAKAK ALKAKKAVLK GVHSHKKKKI RTSPTFRRPK TLRLRRQPKY PRKSAPRRNK LDHYAIIKFP LTTESAMKK IEDNNTLVFI VDVKANKHQI KQAVKKLYDI DVAKVNTLIR PDGEKKAYVR LAPDYDALDV ANKIGII

UniProtKB: Large ribosomal subunit protein uL23

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分子 #48: Ribosomal protein L26

分子名称: Ribosomal protein L26 / タイプ: protein_or_peptide / ID: 48 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 17.303363 KDa
配列文字列:
MKFNPFVTSD RSKNRKRHFN APSHIRRKIM SSPLSKELRQ KYNVRSMPIR KDDEVQVVRG HYKGQQIGKV VQVYRKKYVI YIERVQREK ANGTTVHVGI HPSKVVITRL KLDKDRKKIL ERKAKSRQVG KEKGKYKEET IEKMQE

UniProtKB: Large ribosomal subunit protein uL24

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分子 #50: 60S ribosomal protein L27

分子名称: 60S ribosomal protein L27 / タイプ: protein_or_peptide / ID: 50 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 15.835831 KDa
配列文字列:
MGKFMKPGKV VLVLAGRYSG RKAVIVKNID DGTSDRPYSH ALVAGIDRYP RKVTAAMGKK KIAKRSKIKS FVKVYNYNHL MPTRYSVDI PLDKTVVNKD VFRDPALKRK ARREAKVKFE ERYKTGKNKW FFQKLRF

UniProtKB: Large ribosomal subunit protein eL27

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分子 #51: 60S ribosomal protein L27a

分子名称: 60S ribosomal protein L27a / タイプ: protein_or_peptide / ID: 51 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 16.620561 KDa
配列文字列:
MPSRLRKTRK LRGHVSHGHG RIGKHRKHPG GRGNAGGMHH HRINFDKYHP GYFGKVGMRH YHLKRNQSFC PTVNLDKLWT LVSEQTRVN AAKNKTGAAP IIDVVRSGYY KVLGKGKLPK QPVIVKAKFF SRRAEEKIKG VGGACVLVA

UniProtKB: Large ribosomal subunit protein uL15

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分子 #52: Nascent polypeptide-associated complex subunit alpha

分子名称: Nascent polypeptide-associated complex subunit alpha
タイプ: protein_or_peptide / ID: 52 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 23.406824 KDa
組換発現生物種: Escherichia coli (大腸菌)
配列文字列: MPGEATETVP ATEQELPQPQ AETGSGTESD SDESVPELEE QDSTQATTQQ AQLAAAAEID EEPVSKAKQS RSEKKARKAM SKLGLRQVT GVTRVTIRKS KNILFVITKP DVYKSPASDT YIVFGEAKIE DLSQQAQLAA AEKFKVQGEA VSNIQENTQT P TVQEESEE ...文字列:
MPGEATETVP ATEQELPQPQ AETGSGTESD SDESVPELEE QDSTQATTQQ AQLAAAAEID EEPVSKAKQS RSEKKARKAM SKLGLRQVT GVTRVTIRKS KNILFVITKP DVYKSPASDT YIVFGEAKIE DLSQQAQLAA AEKFKVQGEA VSNIQENTQT P TVQEESEE EEVDETGVEV KDIELVMSQA NVSRAKAVRA LKNNSNDIVN AIMELTM

UniProtKB: Nascent polypeptide-associated complex subunit alpha

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分子 #53: MAGNESIUM ION

分子名称: MAGNESIUM ION / タイプ: ligand / ID: 53 / コピー数: 97 / 式: MG
分子量理論値: 24.305 Da

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分子 #54: ZINC ION

分子名称: ZINC ION / タイプ: ligand / ID: 54 / コピー数: 5 / 式: ZN
分子量理論値: 65.409 Da

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実験情報

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構造解析

手法クライオ電子顕微鏡法
解析単粒子再構成法
試料の集合状態particle

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試料調製

緩衝液pH: 7.5
グリッドモデル: Quantifoil R2/2 / 材質: COPPER / 支持フィルム - 材質: CARBON / 支持フィルム - トポロジー: CONTINUOUS / 前処理 - タイプ: GLOW DISCHARGE / 前処理 - 時間: 15 sec.
凍結凍結剤: ETHANE-PROPANE / チャンバー内湿度: 95 % / 装置: FEI VITROBOT MARK IV

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電子顕微鏡法

顕微鏡FEI TITAN KRIOS
撮影フィルム・検出器のモデル: GATAN K3 (6k x 4k) / 平均電子線量: 50.0 e/Å2
電子線加速電圧: 300 kV / 電子線源: FIELD EMISSION GUN
電子光学系照射モード: FLOOD BEAM / 撮影モード: BRIGHT FIELD / 最大 デフォーカス（公称値）: 3.0 µm / 最小 デフォーカス（公称値）: 1.0 µm
試料ステージ試料ホルダーモデル: FEI TITAN KRIOS AUTOGRID HOLDER
ホルダー冷却材: NITROGEN
実験機器
モデル: Titan Krios / 画像提供: FEI Company

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画像解析

初期モデルモデルのタイプ: INSILICO MODEL
最終 再構成解像度のタイプ: BY AUTHOR / 解像度: 2.83 Å / 解像度の算出法: FSC 0.143 CUT-OFF / 使用した粒子像数: 51843
初期 角度割当タイプ: PROJECTION MATCHING
最終 角度割当タイプ: MAXIMUM LIKELIHOOD

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万見について

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お知らせ

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2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

  • EMDBのヘッダファイルのバージョン3が、公式のフォーマットとなりました。
  • これまでは公式だったバージョン1.9は、アーカイブから削除されます。

関連情報:EMDBヘッダ

外部リンク:wwPDBはEMDBデータモデルのバージョン3へ移行します

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2020年8月12日: 新型コロナ情報

新型コロナ情報

URL: https://pdbj.org/emnavi/covid19.php

新ページ: EM Navigatorに新型コロナウイルスの特設ページを開設しました。

関連情報:Covid-19情報 / 2020年3月5日: 新型コロナウイルスの構造データ

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2020年3月5日: 新型コロナウイルスの構造データ

新型コロナウイルスの構造データ

関連情報:万見生物種 / 2020年8月12日: 新型コロナ情報

外部リンク:COVID-19特集ページ - PDBj / 今月の分子2020年2月：コロナウイルスプロテーアーゼ

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2019年1月31日: EMDBのIDの桁数の変更

EMDBのIDの桁数の変更

  • EMDBエントリに付与されているアクセスコード(EMDB-ID)は4桁の数字(例、EMD-1234)でしたが、間もなく枯渇します。これまでの4桁のID番号は4桁のまま変更されませんが、4桁の数字を使い切った後に発行されるIDは5桁以上の数字(例、EMD-12345)になります。5桁のIDは2019年の春頃から発行される見通しです。
  • EM Navigator/万見では、接頭語「EMD-」は省略されています。

関連情報:Q: 「EMD」とは何ですか？ / 万見/EM NavigatorにおけるID/アクセスコードの表記

外部リンク:EMDB Accession Codes are Changing Soon! / PDBjへお問い合わせ

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2017年7月12日: PDB大規模アップデート

PDB大規模アップデート

  • 新バージョンのPDBx/mmCIF辞書形式に基づくデータがリリースされました。
  • 今回の更新はバージョン番号が4から5になる大規模なもので、全エントリデータの書き換えが行われる「Remediation」というアップデートに該当します。
  • このバージョンアップで、電子顕微鏡の実験手法に関する多くの項目の書式が改定されました(例：em_softwareなど)。
  • EM NavigatorとYorodumiでも、この改定に基づいた表示内容になります。

外部リンク:wwPDB Remediation / OneDepデータ基準に準拠した、より強化された内容のモデル構造ファイルが、PDBアーカイブで公開されました。

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万見 (Yorodumi)

幾万の構造データを、幾万の視点から

  • 万見(Yorodumi)は、EMDB/PDB/SASBDBなどの構造データを閲覧するためのページです。
  • EM Navigatorの詳細ページの後継、Omokage検索のフロントエンドも兼ねています。

関連情報:EMDB / PDB / SASBDB / 3つのデータバンクの比較 / 万見検索 / 2016年8月31日: 新しいEM Navigatorと万見 / 万見文献 / Jmol/JSmol / 機能・相同性情報 / 新しいEM Navigatorと万見の変更点

他の情報も見る