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Open data
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Basic information
Entry | Database: SASBDB / ID: SASDEF6 |
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![]() | Epstein-Barr nuclear antigen 2 (EBNA2 Type1, amino acids 381-455)
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Function / homology | ![]() symbiont-mediated perturbation of host cell cycle progression / host cell nuclear matrix / symbiont-mediated perturbation of host transcription / DNA-templated viral transcription / protein serine/threonine phosphatase inhibitor activity / symbiont-mediated suppression of host translation initiation / symbiont-mediated suppression of host type I interferon-mediated signaling pathway / virus-mediated perturbation of host defense response / host cell nucleus / positive regulation of DNA-templated transcription Similarity search - Function |
Biological species | ![]() |
![]() | ![]() Title: Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts B cell growth Authors: Ponnusamy R / Khatri R / Correia P / Mancini E / Farrell P |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
-Models
Model #2534 | ![]() Type: dummy / Radius of dummy atoms: 2.25 A / Chi-square value: 1.590 / P-value: 0.128072 ![]() |
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Model #2545 | ![]() Type: dummy / Radius of dummy atoms: 2.25 A / Chi-square value: 1.590 / P-value: 0.128072 ![]() |
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Sample
![]() | Name: Epstein-Barr nuclear antigen 2 (EBNA2 Type1, amino acids 381-455) Specimen concentration: 5.4 mg/ml |
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Buffer | Name: 20mM Tris-HCl, 100mM NaCl, 2% Sucrose and 1mM TCEP / pH: 7.5 |
Entity #1341 | Name: EBNA2 Type1 / Type: protein / Description: Epstein-Barr nuclear antigen 2 / Formula weight: 7.831 / Num. of mol.: 2 / Source: Epstein-Barr virus (strain B95-8) / References: UniProt: P12978 Sequence: SMPELSPVLG LHQGQGAGDS PTPGPSNAAP VCRNSHTATP NVSPIHEPES HNSPEAPILF PDDWYPPSID PADLD |
-Experimental information
Beam | Instrument name: Diamond Light Source B21 / City: Didcot / 国: UK ![]() | ||||||||||||||||||||||||||||||
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Detector | Name: Pilatus 2M | ||||||||||||||||||||||||||||||
Scan | Measurement date: Sep 23, 2017 / Storage temperature: 4 °C / Cell temperature: 25 °C / Exposure time: 3 sec. / Number of frames: 18 / Unit: 1/A /
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Distance distribution function P(R) |
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Result | Comments: SEC-SAXS was performed using the following parameters: Column type: S200 3.2/300 increase; Flow rate: 0.075 ml/min; Injection volume: 45 µl; Sample injection concentration: 5.4 mg/ml.
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