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Yorodumi- PDB-4amj: Turkey beta1 adrenergic receptor with stabilising mutations and b... -
+Open data
-Basic information
Entry | Database: PDB / ID: 4amj | ||||||
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Title | Turkey beta1 adrenergic receptor with stabilising mutations and bound biased agonist carvedilol | ||||||
Components | BETA-1 ADRENERGIC RECEPTOR | ||||||
Keywords | MEMBRANE PROTEIN / 7TMR BETA1-ADRENOCEPTOR / STABILISING MUTATIONS / BIASED AGONIST | ||||||
Function / homology | Function and homology information beta1-adrenergic receptor activity / positive regulation of heart rate by epinephrine-norepinephrine / regulation of circadian sleep/wake cycle, sleep / norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure / adenylate cyclase-activating adrenergic receptor signaling pathway / early endosome / identical protein binding / membrane / plasma membrane Similarity search - Function | ||||||
Biological species | MELEAGRIS GALLOPAVO (turkey) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.3 Å | ||||||
Authors | Warne, T. / Edwards, P.C. / Leslie, A.G. / Tate, C.G. | ||||||
Citation | Journal: Structure / Year: 2012 Title: Crystal Structures of a Stabilized Beta1-Adrenoceptor Bound to the Biased Agonists Bucindolol and Carvedilol Authors: Warne, T. / Edwards, P.C. / Leslie, A.G. / Tate, C.G. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 4amj.cif.gz | 140 KB | Display | PDBx/mmCIF format |
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PDB format | pdb4amj.ent.gz | 107.8 KB | Display | PDB format |
PDBx/mmJSON format | 4amj.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 4amj_validation.pdf.gz | 3 MB | Display | wwPDB validaton report |
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Full document | 4amj_full_validation.pdf.gz | 3 MB | Display | |
Data in XML | 4amj_validation.xml.gz | 24.7 KB | Display | |
Data in CIF | 4amj_validation.cif.gz | 33.4 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/am/4amj ftp://data.pdbj.org/pub/pdb/validation_reports/am/4amj | HTTPS FTP |
-Related structure data
Related structure data | 4amiC 2y02S S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1 / Refine code: 1
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