登録情報 データベース : PDB / ID : 3zr7 構造の表示 ダウンロードとリンクタイトル Structural basis for agonism and antagonism for a set of chemically related progesterone receptor modulators 要素PROGESTERONE RECEPTOR 詳細 キーワード RECEPTOR / AGONIST / ANTAGONIST機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
glandular epithelial cell maturation / tertiary branching involved in mammary gland duct morphogenesis / ovulation from ovarian follicle / negative regulation of phosphorylation / paracrine signaling / maintenance of protein location in nucleus / regulation of epithelial cell proliferation / nuclear steroid receptor activity / lung alveolus development / progesterone receptor signaling pathway ... glandular epithelial cell maturation / tertiary branching involved in mammary gland duct morphogenesis / ovulation from ovarian follicle / negative regulation of phosphorylation / paracrine signaling / maintenance of protein location in nucleus / regulation of epithelial cell proliferation / nuclear steroid receptor activity / lung alveolus development / progesterone receptor signaling pathway / estrogen response element binding / nuclear receptor-mediated steroid hormone signaling pathway / Nuclear signaling by ERBB4 / HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand / steroid binding / SUMOylation of intracellular receptors / G protein-coupled receptor activity / Nuclear Receptor transcription pathway / transcription coactivator binding / nuclear receptor activity / cell-cell signaling / ATPase binding / DNA-binding transcription activator activity, RNA polymerase II-specific / Estrogen-dependent gene expression / mitochondrial outer membrane / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / negative regulation of gene expression / signaling receptor binding / regulation of transcription by RNA polymerase II / positive regulation of gene expression / chromatin / regulation of DNA-templated transcription / enzyme binding / signal transduction / positive regulation of transcription by RNA polymerase II / DNA binding / zinc ion binding / nucleoplasm / identical protein binding / plasma membrane / cytosol 類似検索 - 分子機能 Progesterone receptor / Progesterone receptor / : / Retinoid X Receptor / Retinoid X Receptor / Nuclear hormone receptor / Nuclear hormones receptors DNA-binding region signature. / Zinc finger, nuclear hormone receptor-type / Zinc finger, C4 type (two domains) / Nuclear hormone receptors DNA-binding domain profile. ... Progesterone receptor / Progesterone receptor / : / Retinoid X Receptor / Retinoid X Receptor / Nuclear hormone receptor / Nuclear hormones receptors DNA-binding region signature. / Zinc finger, nuclear hormone receptor-type / Zinc finger, C4 type (two domains) / Nuclear hormone receptors DNA-binding domain profile. / c4 zinc finger in nuclear hormone receptors / Nuclear hormone receptor, ligand-binding domain / Nuclear hormone receptor-like domain superfamily / Nuclear receptor (NR) ligand-binding (LBD) domain profile. / Ligand binding domain of hormone receptors / Zinc finger, NHR/GATA-type / Ligand-binding domain of nuclear hormone receptor / Orthogonal Bundle / Mainly Alpha 類似検索 - ドメイン・相同性生物種 HOMO SAPIENS (ヒト)手法 X線回折 / シンクロトロン / OTHER / 解像度 : 1.65 Å 詳細データ登録者 Lusher, S.J. / Raaijmakers, H.C.A. / Vu-Pham, D. / Dechering, K. / Wai Lam, T. / Brown, A.R. / Hamilton, N.M. / Nimz, O. / Azevedo, R. / McGuire, R. ...Lusher, S.J. / Raaijmakers, H.C.A. / Vu-Pham, D. / Dechering, K. / Wai Lam, T. / Brown, A.R. / Hamilton, N.M. / Nimz, O. / Azevedo, R. / McGuire, R. / Oubrie, A. / de Vlieg, J. 引用ジャーナル : J. Biol. Chem. / 年 : 2011タイトル : Structural basis for agonism and antagonism for a set of chemically related progesterone receptor modulators.著者 : Lusher, S.J. / Raaijmakers, H.C. / Vu-Pham, D. / Dechering, K. / Lam, T.W. / Brown, A.R. / Hamilton, N.M. / Nimz, O. / Bosch, R. / McGuire, R. / Oubrie, A. / de Vlieg, J. 履歴 登録 2011年6月15日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2011年8月17日 Provider : repository / タイプ : Initial release改定 1.1 2011年10月26日 Group : Database references改定 1.2 2017年12月27日 Group : Database references / Structure summary / カテゴリ : audit_author / citation / citation_authorItem : _audit_author.name / _citation.journal_abbrev ... _audit_author.name / _citation.journal_abbrev / _citation.journal_id_ISSN / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.title / _citation_author.name 改定 1.3 2024年5月8日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
すべて表示 表示を減らす