EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structural basis for small molecule binding to the SARS-CoV-2 nsp10-nsp14 ExoN complex.
ジャーナル・号・ページ	Nucleic Acids Res., Vol. 53, Year 2025
掲載日	2024年6月28日 (構造データの登録日)
著者	Kozielski, F. / Fisher, S.Z. / Ma, S. / Al Busaidi, F. / Krupinska, E. / Nyblom, M. / Sele, C. / Sullivan, H.M. / Krojer, T. / Knecht, W.
リンク	Nucleic Acids Res. / PubMed:40794865
手法	X線回折
解像度	1.3 - 2.44 Å
構造データ	PDB-9fw2: SARS CoV-2 nsp10 in complex with the ExoN domain from nsp14 手法: X-RAY DIFFRACTION / 解像度: 1.77 Å PDB-9fwh: Crystal Structure of SARS-CoV-2 NSP10-ExoN in complex with VT00019 手法: X-RAY DIFFRACTION / 解像度: 2.35 Å PDB-9fwi: Ensemble model of ligand-free SARS-CoV-2 NSP10-NSP14 (ExoN) and in complex with partially bound VT00025 手法: X-RAY DIFFRACTION / 解像度: 1.533 Å PDB-9fwj: Ensemble model of ligand-free SARS-CoV-2 NSP10-NSP14 (ExoN) and in complex with partially bound VT00079 手法: X-RAY DIFFRACTION / 解像度: 2.424 Å PDB-9fwk: Ensemble model of ligand-free SARS-CoV-2 NSP10-NSP14 (ExoN) and in complex with partially bound VT00123 手法: X-RAY DIFFRACTION / 解像度: 1.509 Å PDB-9fwl: Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00167 手法: X-RAY DIFFRACTION / 解像度: 2.09 Å PDB-9fwm: Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00180 手法: X-RAY DIFFRACTION / 解像度: 1.574 Å PDB-9fwn: Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00219 手法: X-RAY DIFFRACTION / 解像度: 1.866 Å PDB-9fwo: Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00216 手法: X-RAY DIFFRACTION / 解像度: 2.179 Å PDB-9fwp: Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00198 手法: X-RAY DIFFRACTION / 解像度: 2.381 Å PDB-9fwq: Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00218 手法: X-RAY DIFFRACTION / 解像度: 2.322 Å PDB-9fwr: Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00249 手法: X-RAY DIFFRACTION / 解像度: 2.294 Å PDB-9fws: Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00258 手法: X-RAY DIFFRACTION / 解像度: 1.433 Å PDB-9fwt: Ensemble model of ligand-free SARS-CoV-2 NSP10-NSP14 (ExoN) and in complex with partially bound VT00259 手法: X-RAY DIFFRACTION / 解像度: 1.639 Å PDB-9fwu: Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00421 手法: X-RAY DIFFRACTION / 解像度: 1.425 Å PDB-9fz4: SARS CoV-2 nsp10 in complex with theExoN domain from nsp14 手法: X-RAY DIFFRACTION / 解像度: 2.44 Å PDB-9fzk: SARS CoV-2 nsp10 in complex with theExoN domain from nsp14 手法: X-RAY DIFFRACTION / 解像度: 1.3 Å
化合物	ChemComp-ZN: Unknown entry ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-NA: Unknown entry / ナトリウムカチオン ChemComp-HOH: WATER PDB-1igq: C-terminal Domain of Transcriptional Repressor Protein KorB PDB-1igp: X-RAY CRYSTALLOGRAPHIC STUDIES OF RECOMBINANT INORGANIC PYROPHOSPHATASE FROM ESCHERICHIA COLI ChemComp-DMS: DIMETHYL SULFOXIDE / 2-チアプロパン2-オキシド / DMSO, 沈殿剤YM ChemComp-MG: Unknown entry / マグネシウムジカチオン ChemComp-UYY: 2-methoxybenzamide / 2-メトキシベンズアミド PDB-1igt: STRUCTURE OF IMMUNOGLOBULIN PDB-1igs: INDOLE-3-GLYCEROLPHOSPHATE SYNTHASE FROM SULFOLOBUS SOLFATARICUS AT 2.0 A RESOLUTION PDB-1igo: Family 11 xylanase PDB-1igr: Type 1 Insulin-like growth factor receptor (DOMAINS 1-3) PDB-1ign: DNA-BINDING DOMAIN OF RAP1 IN COMPLEX WITH TELOMERIC DNA SITE PDB-1igm: THREE DIMENSIONAL STRUCTURE OF AN FV FROM A HUMAN IGM IMMUNOGLOBULIN PDB-1igk: Unknown entry PDB-1igj: 26-10 FAB:DIGOXIN COMPLEX-AFFINITY AND SPECIFICITY DUE TO SURFACE COMPLEMENTARITY PDB-1igl: SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR II RELATIONSHIP TO RECEPTOR AND BINDING PROTEIN INTERACTIONS 化合物画像なし ChemComp-MI7: Unknown entry ChemComp-VSL: methyl 4,5,6,7-tetrahydro-2H-indazole-3-carboxylate / 4,5,6,7-テトラヒドロ-1H-インダゾ-ル-3-カルボン酸メチル PDB-1igi*: 26-10 FAB:DIGOXIN COMPLEX-AFFINITY AND SPECIFICITY DUE TO SURFACE COMPLEMENTARITY
由来	severe acute respiratory syndrome coronavirus 2 (ウイルス)
キーワード	VIRAL PROTEIN / nsp10 / nsp14 ExoN / SARS CoV-2 / exoribonuclease / nsp14 / fragment screen