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Structure paper

TitleLarge-scale structural analysis of the classical human protein tyrosine phosphatome.
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 136, Page 352-363, Year 2009
Publish dateJul 28, 2005 (structure data deposition date)
AuthorsBarr, A.J. / Ugochukwu, E. / Lee, W.H. / King, O.N. / Filippakopoulos, P. / Alfano, I. / Savitsky, P. / Burgess-Brown, N.A. / Muller, S. / Knapp, S.
External linksCell(Cambridge,Mass. ) / PubMed:19167335
MethodsX-ray diffraction
Resolution1.5 - 3.2 Å
Structure data

PDB-2ahs:
Crystal Structure of the Catalytic Domain of Human Tyrosine Receptor Phosphatase Beta
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-2b49:
Crystal Structure of the Catalytic Domain of Protein Tyrosine Phosphatase, non-receptor Type 3
Method: X-RAY DIFFRACTION / Resolution: 1.54 Å

PDB-2cfv:
Crystal structure of human protein tyrosine phosphatase receptor type J
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-2cjz:
crystal structure of the c472s mutant of human protein tyrosine phosphatase ptpn5 (step, striatum enriched phosphatase) in complex with phosphotyrosine
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-2gjt:
Crystal structure of the human receptor phosphatase PTPRO
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-2h4v:
Crystal Structure of the Human Tyrosine Receptor Phosphatase Gamma
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-2i75:
Crystal Structure of Human Protein Tyrosine Phosphatase N4 (PTPN4)
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

PDB-2jjd:
Protein Tyrosine Phosphatase, Receptor Type, E isoform
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-2nlk:
Crystal structure of D1 and D2 catalytic domains of human Protein Tyrosine Phosphatase Gamma (D1+D2 PTPRG)
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-2nz6:
Crystal structure of the PTPRJ inactivating mutant C1239S
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-2oc3:
Crystal Structure of the Catalytic Domain of Human Protein Tyrosine Phosphatase non-receptor Type 18
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-2ooq:
Crystal Structure of the Human Receptor Phosphatase PTPRT
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-2p6x:
Crystal structure of human tyrosine phosphatase PTPN22
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2pa5:
Crystal structure of human protein tyrosine phosphatase PTPN9
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-2qep:
Crystal structure of the D1 domain of PTPRN2 (IA2beta)
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-3b7o:
Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-NI:
NICKEL (II) ION

ChemComp-PTR:
O-PHOSPHOTYROSINE

ChemComp-FLC:
CITRATE ANION

ChemComp-ACT:
ACETATE ION

ChemComp-SO4:
SULFATE ION

ChemComp-PO4:
PHOSPHATE ION

ChemComp-B3P:
2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-SCN:
THIOCYANATE ION

ChemComp-MLT:
D-MALATE

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Tyrosine Receptor Phosphatase / Beta / Human / Structural Genomics / Structural Genomics Consortium / SGC / Protein Tyrosine Phosphatase / non-receptor Type / RECEPTOR TYPE TYROSINE PHOSPHATASE J / PTPRJ / GLYCOPROTEIN / PROTEIN PHOSPHATASE / STEP / PTPN5 / PHOSPHATASE / Tyrosine phosphatase / PTPRO / GLEPP1 / PTPU2 / GAMMA / PTPN4 / PTP / MEG-1 / TRANSMEMBRANE / PHOSPHOPROTEIN / CONSORTIUM / STRUCTURAL / PTPRE / MEMBRANE / GENOMICS / PTPRG / R-PTP gamma / Protein Tyrosine Phosphatase gamma / D3S1249 / HPTPG / RPTPG / PTPG / D1-D2 catalytic domains / HYDROLASE RECEPTOR TYPE TYROSINE PHOSPHATASE J / Receptor / Lymphoid phosphatase / PEP / LYP / MEG2 / PTPN9 / PTPRN2 / PTPRP / Phogrin / IA-2 beta / autoantigen / SHP2 / PTPN11 / Deafness / Disease mutation / Phosphorylation / SH2 domain

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