Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Activation of RyR1 in native membranes
Journal, issue, pages	To Be Published
Publish date	Jul 17, 2025 (structure data deposition date)
Authors	Mikirtumov V / Golusik S / Sprink T / Balyschew N / Yang W / Kotecha A / Kudryashev M
External links	Search PubMed
Methods	EM (single particle) / EM (subtomogram averaging)
Resolution	3.2 - 25.97 Å
Structure data	EMDB-54431: Focused map of the N-Terminal cytosolic shell part, Apo-state RyR1 in the native membrane solved by "SPA" Method: EM (single particle) / Resolution: 3.73 Å EMDB-54433: Focused map of the BSol cytosolic shell part, Apo-state RyR1 in the native membrane solved by "SPA" Method: EM (single particle) / Resolution: 4.69 Å EMDB-54435: Focused map of the CSol activation core part, Apo-state RyR1 in the native membrane solved by "SPA" Method: EM (single particle) / Resolution: 3.93 Å EMDB-54437: Focused map of the TMD/TaF/CTD part, Apo-state RyR1 in the native membrane solved by "SPA" Method: EM (single particle) / Resolution: 3.65 Å EMDB-54438: Consensus map, Apo-state RyR1 in the native membrane solved by "SPA" Method: EM (single particle) / Resolution: 3.71 Å 54445 9s16 EMDB-54445, PDB-9s16: Apo-state RyR1 in the native membrane solved by "SPA Method: EM (single particle) / Resolution: 3.6 Å EMDB-54449: Consensus map, Apo-state RyR1 with ACP in the native membrane Method: EM (single particle) / Resolution: 4.01 Å EMDB-54450: Focused map of the N-Terminal cytosolic shell part, Apo-state RyR1 with ACP in the native membrane Method: EM (single particle) / Resolution: 3.88 Å EMDB-54451: Focused map of the BSol cytosolic shell part, Apo-state RyR1 with ACP in the native membrane Method: EM (single particle) / Resolution: 5.12 Å EMDB-54452: Focused map of the CSol activation core part, Apo-state RyR1 with ACP in the native membrane Method: EM (single particle) / Resolution: 4.18 Å EMDB-54453: Focused map of the TMD/TaF/CTD part, Apo-state RyR1 with ACP in the native membrane Method: EM (single particle) / Resolution: 4.09 Å 54454 9s1h EMDB-54454, PDB-9s1h: Apo-state RyR1 with ACP in the native membrane Method: EM (single particle) / Resolution: 4.0 Å EMDB-54501: Focused map of the N-Terminal cytosolic shell part, Primed-state RyR1 with calcium in activating concentration in the native membrane Method: EM (single particle) / Resolution: 3.85 Å EMDB-54502: Focused map of the BSol cytosolic shell part, Primed-state RyR1 with calcium in activating concentration in the native membrane Method: EM (single particle) / Resolution: 4.67 Å EMDB-54503: Focused map of the CSol activation core part, Primed-state RyR1 with calcium in activating concentration in the native membrane Method: EM (single particle) / Resolution: 4.02 Å EMDB-54504: Focused map of the TMD/TaF/CTD part, Primed-state RyR1 with calcium in activating concentration in the native membrane Method: EM (single particle) / Resolution: 3.84 Å EMDB-54505: Consensus map, Primed-state RyR1 with calcium in activating concentration in the native membrane Method: EM (single particle) / Resolution: 3.86 Å EMDB-54507: RyR1-RyR1 dimer map, Primed-state RyR1 with calcium in activating concentration in the native membrane Method: EM (single particle) / Resolution: 11.75 Å 54508 9s2r EMDB-54508, PDB-9s2r: Up"-class, Primed-state RyR1 with calcium in activating concentration in the native membrane Method: EM (single particle) / Resolution: 4.19 Å 54509 9s2s EMDB-54509, PDB-9s2s: Primed-state RyR1 with calcium in activating concentration in the native membrane Method: EM (single particle) / Resolution: 3.8 Å EMDB-54512: Focused map of the N-Terminal cytosolic shell part, Primed-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane Method: EM (single particle) / Resolution: 3.3 Å EMDB-54513: Focused map of the BSol cytosolic shell part, Primed-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane Method: EM (single particle) / Resolution: 4.08 Å EMDB-54514: Focused map of the CSol activation core part, Primed-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane Method: EM (single particle) / Resolution: 3.46 Å EMDB-54515: Focused map of the TMD/TaF/CTD part, Primed-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane Method: EM (single particle) / Resolution: 3.21 Å EMDB-54516: Consensus map, Primed-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane Method: EM (single particle) / Resolution: 3.51 Å EMDB-54517: RyR1-RyR1 Dimer map with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane Method: EM (single particle) / Resolution: 18.4 Å 54552 9s3u EMDB-54552, PDB-9s3u: Down class, Primed-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane Method: EM (single particle) / Resolution: 4.77 Å 54553 9s3v EMDB-54553, PDB-9s3v: Primed-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane Method: EM (single particle) / Resolution: 3.2 Å EMDB-54554: Focused map of the N-Terminal cytosolic shell part, Activated-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane Method: EM (single particle) / Resolution: 3.69 Å EMDB-54555: Focused map of the BSol cytosolic shell part, Activated-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane Method: EM (single particle) / Resolution: 4.99 Å EMDB-54557: Focused map of the CSol activation core part, Activated-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane Method: EM (single particle) / Resolution: 3.82 Å EMDB-54562: Focused map of the TMD/TaF/CTD part, Activated-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane Method: EM (single particle) / Resolution: 3.53 Å EMDB-54568: Consensus map, Activated-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane Method: EM (single particle) / Resolution: 3.8 Å 54569 9s4l EMDB-54569, PDB-9s4l: Down class, Activated-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane Method: EM (single particle) / Resolution: 4.92 Å 54570 9s4n EMDB-54570, PDB-9s4n: Activated-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane Method: EM (single particle) / Resolution: 3.53 Å EMDB-54571: Focused map of the N-Terminal cytosolic shell part, Locked-state RyR1 with ryanodine in the native membrane Method: EM (single particle) / Resolution: 3.67 Å EMDB-54572: Focused map of the BSol cytosolic shell part, Locked-state RyR1 with ryanodine in the native membrane Method: EM (single particle) / Resolution: 4.45 Å EMDB-54573: Focused map of the CSol activation core part, Locked-state RyR1 with ryanodine in the native membrane Method: EM (single particle) / Resolution: 3.79 Å EMDB-54574: Focused map of the TMD/TaF/CTD part, Locked-state RyR1 with ryanodine in the native membrane Method: EM (single particle) / Resolution: 3.71 Å EMDB-54575: Consensus map, Locked-state RyR1 with ryanodine in the native membrane Method: EM (single particle) / Resolution: 3.8 Å EMDB-54580: RyR1-RyR1 Dimer map with ryanodine in the native membrane Method: EM (single particle) / Resolution: 13.14 Å EMDB-54587: Focused Map of the Activation core and TMD parts, Apo-state RyR1 in the native membrane solved by StA Method: EM (subtomogram averaging) / Resolution: 3.99 Å 54588 9s54 EMDB-54588, PDB-9s54: Down class, Locked-state RyR1 with ryanodine in the native membrane Method: EM (single particle) / Resolution: 3.9 Å EMDB-54589: Focused map of the N-Terminal cytosolic shell part, Apo-state RyR1 in the native membrane solved by StA Method: EM (subtomogram averaging) / Resolution: 4.03 Å 54590 9s55 EMDB-54590, PDB-9s55: Locked-state RyR1 with ryanodine in the native membrane Method: EM (single particle) / Resolution: 3.7 Å EMDB-54592: Consensus map, Apo-state RyR1 in the native membrane solved by StA Method: EM (subtomogram averaging) / Resolution: 4.59 Å 54593 9s5a EMDB-54593, PDB-9s5a: Down class, Apo-state RyR1 in the native membrane solved by StA Method: EM (subtomogram averaging) / Resolution: 5.98 Å 54594 9s5c EMDB-54594, PDB-9s5c: Up class, Apo-state RyR1 in the native membrane solved by StA Method: EM (subtomogram averaging) / Resolution: 5.98 Å 54595 9s5e EMDB-54595, PDB-9s5e: Tight class, Apo-state RyR1 in the native membrane solved by StA Method: EM (subtomogram averaging) / Resolution: 6.99 Å EMDB-54596: RyR1-RyR1 dimer map, Apo-state RyR1 in the native membrane solved by StA Method: EM (subtomogram averaging) / Resolution: 25.97 Å 54597 9s5f EMDB-54597, PDB-9s5f: Apo-state RyR1 in the native membrane solved by StA Method: EM (subtomogram averaging) / Resolution: 4.0 Å EMDB-54598: Focused map of the TMD/TaF/CTD part, Primed-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane solved by StA Method: EM (subtomogram averaging) / Resolution: 4.43 Å EMDB-54600: Focused map of the CSol activation core part, Primed-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane solved by StA Method: EM (subtomogram averaging) / Resolution: 4.48 Å EMDB-54601: Focused map of the BSol cytosolic shell part, Primed-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane solved by StA Method: EM (subtomogram averaging) / Resolution: 5.5 Å EMDB-54611: Focused map of the N-Terminal cytosolic shell part, Primed-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane solved by StA Method: EM (subtomogram averaging) / Resolution: 4.42 Å EMDB-54612: Consensus map, Primed-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane solved by StA Method: EM (subtomogram averaging) / Resolution: 4.88 Å EMDB-54614: RyR1-RyR1 Dimer map, Primed-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane solved by StA Method: EM (subtomogram averaging) / Resolution: 20.0 Å 54615 9s5w EMDB-54615, PDB-9s5w: Down class, Primed-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane solved by StA Method: EM (subtomogram averaging) / Resolution: 4.94 Å 54616 9s5y EMDB-54616, PDB-9s5y: Up class, Primed-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane solved by StA Method: EM (subtomogram averaging) / Resolution: 6.82 Å 54617 9s5z EMDB-54617, PDB-9s5z: Primed-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane solved by StA Method: EM (subtomogram averaging) / Resolution: 4.43 Å
Chemicals	ChemComp-POV: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate / phospholipidYM ChemComp-ZN: Unknown entry ChemComp-ACP: PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER / AMP-PCP, energy-carrying molecule analogueYM ChemComp-CA: Unknown entry ChemComp-CFF: CAFFEINE / medication*YM
Source	oryctolagus cuniculus (rabbit)
Keywords	MEMBRANE PROTEIN / ryanodine receptor type 1 / ryr1 / skeletal muscle / sarcoplasmic reticulum / SR / native membrane