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全データ118,082件中、1から20件目までを表示しています
-Structure of LGR4 with NB21
-Carbamoyl transferase NovN involved in Novobiocin biosynthesis
To Be Published,
Gomez Garcia, I. / Lawson, D.M.
手法: X線回折
-Ketoreductase Engineering for a Chemoenzymatic Fluorination and Dynamic Kinetic Reduction Cascade
Acs Catalysis, Page 13059-13068, Year 2025
Chun, S.W. / Kosjek, B. / Cahn, J.K.B. / Makarewicz, A.M. / Cheung-Lee, W.L. / Verma, D. / Jones, C.M. / Hruza, A. / Forstater, J.H. / Li, S. ...Chun, S.W. / Kosjek, B. / Cahn, J.K.B. / Makarewicz, A.M. / Cheung-Lee, W.L. / Verma, D. / Jones, C.M. / Hruza, A. / Forstater, J.H. / Li, S. / Gallagher, Q. / Murphy, G.S. / Moore, J.C.
手法: X線回折
-Crystal structure of C270S mutant of Papain-like protease (PLpro) from SARS-CoV-2
To Be Published,
Arya, R. / Ganesh, J. / Prashar, V. / Kumar, M.
手法: X線回折
-Crystal structure of the human DCAF1 WDR domain in complex with OICR-40156
To be published,
Kimani, S. / Dong, A. / Li, Y. / Seitova, A. / Krausser, C. / Wilson, B. / Al-awar, R. / Ackloo, S. / Arrowsmith, C.H. / Edwards, A.M. ...Kimani, S. / Dong, A. / Li, Y. / Seitova, A. / Krausser, C. / Wilson, B. / Al-awar, R. / Ackloo, S. / Arrowsmith, C.H. / Edwards, A.M. / Halabelian, L. / Structural Genomics Consortium (SGC)
手法: X線回折
-Engineering an Imine Reductase for Enantioselective Synthesis of Atropisomeric Amides
To Be Published,
Huang, L. / Fu, H.G. / Song, D.Q. / Yao, Z.C. / Meng, R.Z. / Zhou, Z.T. / Yu, L.Y. / Wu, Z.Y.
手法: X線回折
-Bifunctional Non-haem Iron Oxygenase NovR Involved in Novobiocin Biosynthesis with product bound
To Be Published,
Keller, S. / Lawson, D.M.
手法: X線回折
-Synthetic alpha-synuclein fibrils replicate in mice causing MSA neuropathology
To Be Published, Year 2024
Burger D / Kashyrina M / van den Heuvel L / de La Seigliere H / Lewis AJ / De Nuccio F / Mohammed I / Verchere J / Feuillie C / Berbon M ...Burger D / Kashyrina M / van den Heuvel L / de La Seigliere H / Lewis AJ / De Nuccio F / Mohammed I / Verchere J / Feuillie C / Berbon M / Arotcarena M / Retailleau A / Bezard E / Canron M / Meissner WG / Loquet A / Bousset L / Poujol C / Nilsson KPR / Laferriere F / Baron T / Lofrumento DD / De Giorgi F / Stahlberg H / Ichas F
手法: EM (らせん対称)
-Toward a Random Background for Ligand Optimization
To Be Published,
Xu X / Mailhot O / Correy G / Huang XP / Braz J / Shi D / Srinivasan K / Holota Y / Kuziv Y / Tsoutsouvas C ...Xu X / Mailhot O / Correy G / Huang XP / Braz J / Shi D / Srinivasan K / Holota Y / Kuziv Y / Tsoutsouvas C / Levinzon N / Doruk YU / Rachman M / Diolaiti M / Stevens M / Liu F / Hubner H / Wang J / Wu Y / Ashworth A / Makriyannis A / Zhang Y / Moroz Y / Gmeiner P / Abel R / Manglik A / Basbaum A / Roth B / Fraser J / Shoichet B
手法: EM (単粒子)
-Crystal structure of a SnoaL-like domain-containing protein from Mycobacterium ulcerans
To be published,
Ung, A.R. / Lovell, S. / Liu, L. / Buchko, G.W. / Battaile, K.P.
手法: X線回折
-In situ structural analysis of mammalian cells using a 200 kV electron cryomicroscope
Biorxiv, Year 2025
Szwedziak P
手法: EM (サブトモグラム平均)
-Structure of the microtubule-anchoring factor NEDD1 bound to the γ-tubulin ring complex.
J Cell Biol, Vol. 224, Issue 8, Year 2025
Hugo Muñoz-Hernández / Yixin Xu / Aitor Pellicer Camardiel / Daniel Zhang / Allen Xue / Amol Aher / Ellie Walker / Florina Marxer / Tarun M Kapoor / Michal Wieczorek
手法: EM (単粒子)
-Functional and structural characterization of treatment-emergent nirmatrelvir resistance mutations at low frequencies in the main protease (Mpro) reveals a unique evolutionary route for SARS-CoV-2 to gain resistance.
J Infect Dis, Year 2025
Deschenes, N.M. / Perez-Vargas, J. / Zhong, Z. / Thomas, M. / Kenward, C. / Mosimann, W.A. / Worrall, L.J. / Waglechner, N. / Li, A.X. / Maguire, F. ...Deschenes, N.M. / Perez-Vargas, J. / Zhong, Z. / Thomas, M. / Kenward, C. / Mosimann, W.A. / Worrall, L.J. / Waglechner, N. / Li, A.X. / Maguire, F. / Aftanas, P. / Smith, J.R. / Lim, J. / Young, R.N. / Cherkasov, A. / Farooqi, L. / Moinuddin, A. / Siddiqi, L. / Malik, I. / Lefebvre, M. / Paetzel, M. / Strynadka, N.C.J. / Jean, F. / McGeer, A. / Kozak, R.A.
手法: X線回折
-A Concise and Modular Approach to Generate Novel ROR gamma Agonists.
J. Med. Chem., Year 2025
Fukuda, S. / Ikenogami, T. / Otake, K. / Miwa, S. / Maeda, K. / Yamashita, T. / Inami, T. / Yokota, M. / Lu, Y. / Suma, A. ...Fukuda, S. / Ikenogami, T. / Otake, K. / Miwa, S. / Maeda, K. / Yamashita, T. / Inami, T. / Yokota, M. / Lu, Y. / Suma, A. / Hirono, Y. / Ogawa, N. / Inoue, T. / Harada, K. / Yamaguchi, K. / Akai, S. / Nomura, A. / Adachi, T. / Terawaki, T. / Suzukawa, A. / Kitamoto, M. / Tanimoto, M. / Noguchi, T. / Hata, T. / Kawahara, I. / Iwamoto, K. / Kondo, K. / Kitagawa, Y. / Naka, Y. / Crowe, P. / Tao, H. / Fenn, M. / Thacher, S. / Oba, M. / Shiozaki, M.
手法: X線回折
-A new protein-dependent riboswitch activates ribosomal frameshifting
Biorxiv, Year 2025
Betts, J.K. / Jeffries, C.M. / Passchier, T.C. / Kung, H.C.Y. / Graham, S.P. / Abdelhamid, M.A. / Howard, J.A.L. / Craggs, T.D. / Graham, S.C. / Brierley, I. ...Betts, J.K. / Jeffries, C.M. / Passchier, T.C. / Kung, H.C.Y. / Graham, S.P. / Abdelhamid, M.A. / Howard, J.A.L. / Craggs, T.D. / Graham, S.C. / Brierley, I. / Leake, M.C. / Quinn, S.D. / Hill, C.H.
手法: X線回折
-Crystal structure of Glyceraldehyde-3-phosphate dehydrogenase from Bordetella pertussis (Apo, trigonal form)
To be published,
Ung, A.R. / Liu, L. / Lovell, S. / Battaile, K.P.
手法: X線回折
-Crystal structure of Glyceraldehyde-3-phosphate dehydrogenase from Bordetella pertussis (NAD bound)
To be published,
Liu, L. / Ung, A.R. / Lovell, S. / Battaile, K.P.
手法: X線回折
-Crystal structure of nucleoside-diphosphate kinase Cryptosporidium parvum in complex with ATP
To be published,
Liu, L. / Lovell, S. / Battaile, K.P.
手法: X線回折
-Comparison of fully-sampled and sparse cryo-STEM tomography 3D reconstructions
To Be Published,
Trepout S
手法: EM (トモグラフィー)
-Crystal structure of nucleoside-diphosphate kinase Cryptosporidium parvum in complex with AMP
To be published,
Enayati, P. / Liu, L. / Lovell, S. / Battaile, K.P.
手法: X線回折
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