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Structure paper

TitleStructural genomics of protein phosphatases.
Journal, issue, pagesJ. STRUCT. FUNCT. GENOM., Vol. 8, Page 121-140, Year 2007
Publish dateDec 18, 2003 (structure data deposition date)
AuthorsAlmo, S.C. / Bonanno, J.B. / Sauder, J.M. / Emtage, S. / Dilorenzo, T.P. / Malashkevich, V. / Wasserman, S.R. / Swaminathan, S. / Eswaramoorthy, S. / Agarwal, R. ...Almo, S.C. / Bonanno, J.B. / Sauder, J.M. / Emtage, S. / Dilorenzo, T.P. / Malashkevich, V. / Wasserman, S.R. / Swaminathan, S. / Eswaramoorthy, S. / Agarwal, R. / Kumaran, D. / Madegowda, M. / Ragumani, S. / Patskovsky, Y. / Alvarado, J. / Ramagopal, U.A. / Faber-Barata, J. / Chance, M.R. / Sali, A. / Fiser, A. / Zhang, Z.Y. / Lawrence, D.S. / Burley, S.K.
External linksJ. STRUCT. FUNCT. GENOM. / PubMed:18058037
MethodsX-ray diffraction
Resolution1.6 - 3 Å
Structure data

PDB-1rxd:
Crystal structure of human protein tyrosine phosphatase 4A1
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2fh7:
Crystal structure of the phosphatase domains of human PTP SIGMA
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2g59:
Crystal Structure of the Catalytic Domain of Protein Tyrosine Phosphatase from Homo sapiens
Method: X-RAY DIFFRACTION / Resolution: 2.19 Å

PDB-2hcm:
Crystal structure of mouse putative dual specificity phosphatase complexed with zinc tungstate, New York Structural Genomics Consortium
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2hhl:
Crystal structure of the human small CTD phosphatase 3 isoform 1
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-2hxp:
Crystal Structure of the human phosphatase (DUSP9)
Method: X-RAY DIFFRACTION / Resolution: 1.83 Å

PDB-2hy3:
Crystal structure of the human tyrosine receptor phosphate gamma in complex with vanadate
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-2i0o:
Crystal structure of Anopheles gambiae Ser/Thr phosphatase complexed with Zn2+
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-2i1y:
Crystal structure of the phosphatase domain of human PTP IA-2
Method: X-RAY DIFFRACTION / Resolution: 2.23 Å

PDB-2i44:
Crystal structure of serine-threonine phosphatase 2C from Toxoplasma gondii
Method: X-RAY DIFFRACTION / Resolution: 2.04 Å

PDB-2iq1:
Crystal structure of human PPM1K
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-2irm:
Crystal structure of mitogen-activated protein kinase kinase kinase 7 interacting protein 1 from Anopheles gambiae
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-2isn:
Crystal structure of a phosphatase from a pathogenic strain Toxoplasma gondii
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2nv5:
Crystal structure of a C-terminal phosphatase domain of Rattus norvegicus ortholog of human protein tyrosine phosphatase, receptor type, D (PTPRD)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2oyc:
Crystal structure of human pyridoxal phosphate phosphatase
Method: X-RAY DIFFRACTION / Resolution: 1.72 Å

PDB-2p27:
Crystal Structure of Human Pyridoxal Phosphate Phosphatase with Mg2+ at 1.9 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2p4u:
Crystal structure of acid phosphatase 1 (Acp1) from Mus musculus
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2p69:
Crystal Structure of Human Pyridoxal Phosphate Phosphatase with PLP
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-2p8e:
Crystal structure of the serine/threonine phosphatase domain of human PPM1B
Method: X-RAY DIFFRACTION / Resolution: 1.816 Å

PDB-2pbn:
Crystal structure of the human tyrosine receptor phosphate gamma
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-2q5e:
Crystal structure of human carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2
Method: X-RAY DIFFRACTION / Resolution: 2.51 Å

PDB-2qjc:
Crystal structure of a putative diadenosine tetraphosphatase
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-2r0b:
Crystal structure of human tyrosine phosphatase-like serine/threonine/tyrosine-interacting protein
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-HOH:
WATER / Water

ChemComp-PO4:
PHOSPHATE ION / Phosphate

ChemComp-WO4:
TUNGSTATE(VI)ION

ChemComp-ZN:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-GOL:
GLYCEROL / Glycerol

ChemComp-KEG:
12-TUNGSTOPHOSPHATE

ChemComp-VO4:
VANADATE ION / Vanadate

ChemComp-CA:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-SO4:
SULFATE ION / Sulfate

ChemComp-PR:
PRASEODYMIUM ION / Praseodymium

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE / Pyridoxal phosphate

ChemComp-MN:
Unknown entry

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
  • anopheles gambiae (African malaria mosquito)
  • toxoplasma gondii (eukaryote)
  • rattus norvegicus (Norway rat)
  • trypanosoma brucei (eukaryote)
Keywordsstructural genomics / unknown function / NYSGXRC / PSI / Protein Structure Initiative / New York SGX Research Center for Structural Genomics / HYDROLASE / receptor protein tyrosine phosphatase / Dual domain phosphatase / Protein Tyrosine Phosphatase / Dephosphorylation / PHOSPHATASE / CTD phosphatase / Keggins anion / 8638a / Human Phosphatase / PSI-2 / twisted mixed beta-sheets flanked by {alpha}-helices / beta sandwich / Receptor-type protein tyrosine phosphatase precursor / 8817z / protein phosphatase 2C kappa / TRANSFERASE / TAK1-binding protein / TAB1 / mitogen-activated protein kinase kinase kinase 7 interacting protein 1 / 8828z / pathogenic strain / praseodymium / sulfate / New York Structural Genomics Research Consortium / NYSGRC / 9095b / putative diadenosine tetraphosphatase / monomer / Protein phosphatase

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