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Showing all 15 items for (author: snead & dm)

EMDB-25649:
Helical Reconstruction of the C-terminal Half of Leucine Rich Repeat Kinase 2 (LRRK2) (I2020T) bound to 11-protofilament microtubule in presence of MLi-2 kinase inhibitor
Method: helical / : Matyszewski M, Leschziner AE

EMDB-25658:
Local refinement of the C-terminal Half of Leucine Rich Repeat Kinase 2 (LRRK2) (I2020T) bound to 11-protofilament microtubule in presence of MLi-2 kinase inhibitor
Method: single particle / : Matyszewski M, Leschziner AE

EMDB-25664:
Local Refinement of the C-terminal Half of Leucine Rich Repeat Kinase 2 (LRRK2) (I2020T) tetramer bound to 11-protofilament microtubule in presence of MLi-2 kinase inhibitor
Method: single particle / : Matyszewski M, Leschziner AE

EMDB-25672:
Structure of the C-terminal half of Leucine Rich Repeat Kinase 1 (LRRK1)
Method: single particle / : Matyszewski M, Snead DM, Leschziner AE

EMDB-25674:
Local refinement of the C-terminal Half of Leucine Rich Repeat Kinase 2 (LRRK2) (I2020T) bound to 12-protofilament microtubule without kinase inhibitors present
Method: single particle / : Matyszewski M, Leschziner AE

EMDB-25897:
Local refinement of the C-terminal Half of Leucine Rich Repeat Kinase 2 (LRRK2) (I2020T) bound to 11-protofilament microtubule focused on the monomer in presence of MLi-2 kinase inhibitor
Method: single particle / : Matyszewski M, Leschziner AE

EMDB-25906:
Structure of Leucine Rich Repeat Kinase 2's ROC domain interacting with the microtubule facing the minus end
Method: single particle / : Matyszewski M, Leschziner AE

EMDB-25907:
Structure of Leucine Rich Repeat Kinase 2's ROC domain interacting with the microtubule facing the plus end
Method: single particle / : Matyszewski M, Leschziner AE

EMDB-25908:
2 microtubule protofilaments locally refined from Leucine Rich Repeat Kinase 2 filament structure bound to 11-protofilament microtubules
Method: single particle / : Matyszewski M, Leschziner AE

EMDB-21250:
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Method: single particle / : Leschziner A, Deniston C, Lahiri I

EMDB-21306:
Cryo-EM map of the C-terminal half of Leucine Rich Repeat Kinase 2 as a monomer at 8.1 angstroms
Method: single particle / : Leschziner A, Deniston C, Lahiri I

EMDB-21309:
Cryo-EM map of C-terminal half of Leucine Rich Repeat Kinase 2 as a COR-COR domain dimer at 9.5 angstroms
Method: single particle / : Leschziner A, Deniston C, Lahiri I

EMDB-21310:
Cryo-EM map of C-terminal half of Leucine Rich Repeat Kinase 2 as a WD40-WD40 domain dimer at 13.4 angstroms
Method: single particle / : Leschziner A, Deniston C, Lahiri I

EMDB-21311:
Cryo-EM map of C-terminal half of Leucine Rich Repeat Kinase 2 as a COR-COR domain dimer in the presence of the MLi-2 kinase inhibitor at 9.0 angstroms
Method: single particle / : Leschziner A, Deniston C, Lahiri I

EMDB-21312:
Cryo-EM map of C-terminal half of Leucine Rich Repeat Kinase 2 as a WD40-WD40 domain dimer in the presence of the MLi-2 kinase inhibitor at 10.2 angstroms
Method: single particle / : Leschziner A, Deniston C, Lahiri I

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

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