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Showing 1 - 50 of 55 items for (author: shoichet & b)

EMDB-40207:
Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and Z1834339853

EMDB-42676:
5-HT2AR bound to Lisuride in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)

EMDB-42999:
5HT2AR-miniGq heterotrimer in complex with a novel agonist obtained from large scale docking

PDB-8uwl:
5-HT2AR bound to Lisuride in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)

PDB-8v6u:
5HT2AR-miniGq heterotrimer in complex with a novel agonist obtained from large scale docking

EMDB-29898:
Cannabinoid receptor 1-Gi complex with novel ligand

PDB-8gag:
Cannabinoid receptor 1-Gi complex with novel ligand

EMDB-40768:
TMEM16F 1PBC

PDB-8sun:
TMEM16F 1PBC

EMDB-40776:
TMEM16F bound with Niclosamide

EMDB-41134:
TMEM16F, with Calcium and PIP2, no inhibitor

EMDB-41136:
TMEM16F, with Calcium and PIP2, no inhibitor, Cl2

EMDB-41137:
TMEM16F, with Calcium and PIP2, no inhibitor, Cl1

PDB-8sur:
TMEM16F bound with Niclosamide

PDB-8tag:
TMEM16F, with Calcium and PIP2, no inhibitor

PDB-8tai:
TMEM16F, with Calcium and PIP2, no inhibitor, Cl2

PDB-8tal:
TMEM16F, with Calcium and PIP2, no inhibitor, Cl1

EMDB-26160:
Structure of human serotonin transporter bound to small molecule '8090 in lipid nanodisc and NaCl

PDB-7txt:
Structure of human serotonin transporter bound to small molecule '8090 in lipid nanodisc and NaCl

EMDB-27752:
CryoEM structure of Gq-coupled MRGPRX1 with peptide agonist BAM8-22

EMDB-27753:
CryoEM structure of Gq-coupled MRGPRX1 with peptide ligand BAM8-22 and positive allosteric modulator ML382

EMDB-27754:
CryoEM structure of Gq-coupled MRGPRX1 with ligand Compound-16

PDB-8dwc:
CryoEM structure of Gq-coupled MRGPRX1 with peptide agonist BAM8-22

PDB-8dwg:
CryoEM structure of Gq-coupled MRGPRX1 with peptide ligand BAM8-22 and positive allosteric modulator ML382

PDB-8dwh:
CryoEM structure of Gq-coupled MRGPRX1 with ligand Compound-16

EMDB-32331:
Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a G protein biased agonist

EMDB-32342:
Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a biased agonist

PDB-7w6p:
Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a G protein biased agonist

PDB-7w7e:
Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a biased agonist

EMDB-26597:
CryoEM structure of Go-coupled 5-HT5AR in complex with 5-CT

EMDB-26598:
CryoEM structure of Go-coupled 5-HT5AR in complex with Lisuride

EMDB-26599:
CryoEM structure of Go-coupled 5-HT5AR in complex with Methylergometrine

PDB-7um5:
CryoEM structure of Go-coupled 5-HT5AR in complex with 5-CT

PDB-7um6:
CryoEM structure of Go-coupled 5-HT5AR in complex with Lisuride

PDB-7um7:
CryoEM structure of Go-coupled 5-HT5AR in complex with Methylergometrine

EMDB-24378:
5-HT2AR bound to a novel agonist in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)

PDB-7ran:
5-HT2AR bound to a novel agonist in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)

EMDB-24896:
CryoEM structure of Gq-coupled MRGPRX2 with peptide agonist Cortistatin-14

EMDB-24897:
CryoEM structure of Gi-coupled MRGPRX2 with peptide agonist Cortistatin-14

EMDB-24898:
CryoEM structure of Gq-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573

EMDB-24899:
CryoEM structure of Gi-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573

EMDB-24900:
CryoEM structure of Gq-coupled MRGPRX4 with small molecule agonist MS47134

PDB-7s8l:
CryoEM structure of Gq-coupled MRGPRX2 with peptide agonist Cortistatin-14

PDB-7s8m:
CryoEM structure of Gi-coupled MRGPRX2 with peptide agonist Cortistatin-14

PDB-7s8n:
CryoEM structure of Gq-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573

PDB-7s8o:
CryoEM structure of Gi-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573

PDB-7s8p:
CryoEM structure of Gq-coupled MRGPRX4 with small molecule agonist MS47134

EMDB-22829:
Human Tom70 in complex with SARS CoV2 Orf9b

PDB-7kdt:
Human Tom70 in complex with SARS CoV2 Orf9b

EMDB-21669:
HTR2A bound to 25-CN-NBOH in complex with a mini-Galpha-q protein, beta/gamma subunits and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)

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Feb 9, 2022. New format data for meta-information of EMDB entries

New format data for meta-information of EMDB entries

  • Version 3 of the EMDB header file is now the official format.
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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

  • The Nobel Prize in Physiology or Medicine 2021 was awarded jointly to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch."
  • EM Navigator can help to find cryo-EM structure data by both pioneers.

External links:The Nobel Prize in Physiology or Medicine 2021 - NobelPrize.org / Structure data by Ardem Patapoutian / Structure data by David Julius

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