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Showing 1 - 50 of 51 items for (author: horn-ghetko & d)

EMDB-54793: 
Structure of Neddylated CUL5 C-terminal region-RBX2-ARIH2~L3A2-1~Ub
Method: single particle / : Schulman BA, Du J

EMDB-54794: 
Structure of RBR E2 variant binding to CUL5-RBX2 bound ARIH2
Method: single particle / : Schulman BA, Du J

EMDB-54795: 
Cryo-EM map of focus refined ASB9-Elob/C-CKB bound to Nedd8-CUL5-RBX2-ARIH2-L3A2-1
Method: single particle / : Schulman BA, Du J

EMDB-54892: 
consensus map of Neddylated CUL5-ARIH2-L3A2-1 bound to ASB9-EloB/C-CKB
Method: single particle / : Schulman BA, Du J

EMDB-54893: 
Focus refined map of Neddylated CUL5-ARIH2-L3A2-1 bound to ASB9-EloB/C-CKB, focus refined on ARIH2-L3A2-1
Method: single particle / : Schulman BA, Du J

EMDB-54933: 
Consensus Map of Neddylated CUL5 C-terminal region-RBX2-ARIH2~L3A2-1~Ub
Method: single particle / : Schulman BA, Du J

EMDB-54934: 
Focus refined map of Neddylated CUL5 C-terminal region-RBX2-ARIH2~L3A2-1~Ub
Method: single particle / : Schulman BA, Du J

PDB-9sdx: 
Structure of RBR binding E2 variant crosslinked with NEDD8-CUL5-RBX2 bound ARIH2 and Ub
Method: single particle / : Schulman BA, Du J

PDB-9sdy: 
Structure of RBR E2 variant binding to CUL5-RBX2 bound ARIH2
Method: single particle / : Schulman BA, Du J

EMDB-18214: 
Structure of CUL9-RBX1 ubiquitin E3 ligase complex - hexameric assembly
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

EMDB-18216: 
Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated and neddylated conformation - focused cullin dimer
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

EMDB-18217: 
Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated and neddylated conformation - focused on E2-like density
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

EMDB-18218: 
Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated and neddylated conformation - focused dimeric core
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

EMDB-18220: 
Structure of the hexameric CUL9-RBX1 complex with deletion of CUL9 CPH domain
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

EMDB-18221: 
Structure of the hexameric CUL9-RBX1 complex with deletion of CUL9 DOC domain
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

EMDB-18222: 
Structure of the hexameric CUL9-RBX1 complex with deletion of CUL9 ARM9 domain
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

EMDB-18223: 
Structure of the hexameric CUL9-RBX1 complex with deletion of CUL9 ARIH-RBR element
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

EMDB-19179: 
Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated conformation - symmetry expanded unneddylated dimer
Method: single particle / : Hopf LVM, Horn-Ghetko D, Prabu JR, Schulman BA

PDB-8q7e: 
Structure of CUL9-RBX1 ubiquitin E3 ligase complex - hexameric assembly
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

PDB-8q7h: 
Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated and neddylated conformation - focused cullin dimer
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

PDB-8rhz: 
Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated conformation - symmetry expanded unneddylated dimer
Method: single particle / : Hopf LVM, Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-16355: 
Structure of Dimeric HECT E3 Ubiquitin Ligase UBR5
Method: single particle / : Hehl LA, Prabu JR, Schulman BA

EMDB-16356: 
Structure of HECT E3 UBR5 forming K48 linked Ubiquitin chains
Method: single particle / : Hehl LA, Prabu JR, Schulman BA

EMDB-16865: 
Tetrameric HECT E3 Ubiquitin Ligase UBR5
Method: single particle / : Hehl LA, Prabu JR, Schulman BA

EMDB-16866: 
Cryo-EM map of ubiquitin-VME bound HECT E3 ligase UBR5
Method: single particle / : Hehl LA, Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-16867: 
Ubiquitin transfer from E2 to E3: UBE2D2-ubiquitin linked to HECT E3 ligase UBR5
Method: single particle / : Hehl LA, Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-17466: 
Cryo-EM map of HECT E3 ligase UBR5 forming K48 linked ubiquitin chains
Method: single particle / : Hehl LA, Prabu JR, Schulman BA

PDB-8c06: 
Structure of Dimeric HECT E3 Ubiquitin Ligase UBR5
Method: single particle / : Hehl LA, Prabu JR, Schulman BA

PDB-8c07: 
Structure of HECT E3 UBR5 forming K48 linked Ubiquitin chains
Method: single particle / : Hehl LA, Prabu JR, Schulman BA

EMDB-12995: 
Structure of Neddylated CUL5 C-terminal region-RBX2-ARIH2*
Method: single particle / : Kostrhon SP, prabu JR

EMDB-12998: 
Structure of Neddylated CRL5Vif-CBFbeta-ARIH2*-APOBEC3C (A3C fullcomplex consensus )
Method: single particle / : Kostrhon SP, Prabu JR, Schulman BA

EMDB-12999: 
Structure of Neddylated CUL5 C-terminal region-RBX2-ARIH2* ( A3G E3-E3 catalytic focused )
Method: single particle / : Kostrhon SP, Prabu JR, Schulman BA

EMDB-13000: 
Structure of Neddylated CRL5Vif-CBFbeta-ARIH2*-APOBEC3C (A3C consensus )
Method: single particle / : Kostrhon SP, Prabu JR, Schulman BA

EMDB-13001: 
Structure of Neddylated CRL5Vif-CBFbeta-ARIH2*-APOBEC3G ( A3G consensus )
Method: single particle / : Kostrhon SP, prabu JR, Schulman BA

PDB-7oni: 
Structure of Neddylated CUL5 C-terminal region-RBX2-ARIH2*
Method: single particle / : Kostrhon SP, prabu JR, Schulman BA

EMDB-12040: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

PDB-7b5m: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12004: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 ligase superassembly. NEDD8-CUL1-RBX1-SKP1-FBXW7-Cyclin E-ARIH1-UBE2L3~Ub. Pre-Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12005: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-FBXW7-Cyclin E-ARIH1~Ub. post-Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12006: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-FBXW7-Cyclin E~Ub~ARIH1. Transition State 2
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12036: 
Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12037: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12038: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12039: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-FBXW7-Cyclin E~Ub~ARIH1. Transition State 2
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12041: 
Focused map-catalytic side. Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-UBE2L3~Ub~ARIH1.
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12048: 
Focused map- CyclinA-CDK2-class. Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27. Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12050: 
Focused map- Cullin scaffold. Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

PDB-7b5l: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

PDB-7b5n: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-UBE2L3~Ub~ARIH1.
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

PDB-7b5r: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA
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