Author results

4WKA
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CRYSTAL STRUCTURE OF HUMAN CHITOTRIOSIDASE-1 CATALYTIC DOMAIN AT 0.95 A RESOLUTION
Descriptor:Chitotriosidase-1, L(+)-TARTARIC ACID
Authors:Fadel, F., Zhao, Y., Cachau, R., Cousido-Siah, A., Ruiz, F.X., Harlos, K., Howard, E., Mitschler, A., Podjarny, A.
Deposit date:2014-10-02
Release date:2015-07-08
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM.
Acta Crystallogr.,Sect.D, 71, 2015
1MN8
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STRUCTURE OF MOLONEY MURINE LEUKAEMIA VIRUS MATRIX PROTEIN
Descriptor:Core protein p15
Authors:Riffel, N., Harlos, K., Iourin, O., Rao, Z., Kingsman, A., Stuart, D., Fry, E.
Deposit date:2002-09-05
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:Atomic resolution structure of Moloney murine leukaemia virus matrix protein and its relationship to other retroviral matrix proteins.
Structure, 10, 2002
2X46
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CRYSTAL STRUCTURE OF SEMET ARG R 1
Descriptor:ALLERGEN ARG R 1, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Paesen, G.C., Siebold, C., Syme, N., Harlos, K., Graham, S.C., Hilger, C., Homans, S.W., Hentges, F., Stuart, D.I.
Deposit date:2010-01-28
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:Crystal Structure of the Allergen Arg R 1, a Histamine-Binding Lipocalin from a Soft Tick
To be Published
4WJX
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CRYSTAL STRUCTURE OF HUMAN CHITOTRIOSIDASE-1 CATALYTIC DOMAIN AT 1.0 A RESOLUTION
Descriptor:Chitotriosidase-1, L(+)-TARTARIC ACID
Authors:Fadel, F., Zhao, Y., Cachau, R., Cousido-Siah, A., Ruiz, F.X., Harlos, K., Howard, E., Mitschler, A., Podjarny, A.
Deposit date:2014-10-01
Release date:2015-07-08
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (1 Å)
Cite:New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM
Acta Crystallogr.,Sect.D, 71, 2015
4WKH
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CRYSTAL STRUCTURE OF HUMAN CHITOTRIOSIDASE-1 CATALYTIC DOMAIN IN COMPLEX WITH CHITOBIOSE (1MM) AT 1.05 A RESOLUTION
Descriptor:Chitotriosidase-1, DI(N-ACETYL-D-GLUCOSAMINE)
Authors:Fadel, F., Zhao, Y., Cachau, R., Cousido-Siah, A., Ruiz, F.X., Harlos, K., Howard, E., Mitschler, A., Podjarny, A.
Deposit date:2014-10-02
Release date:2015-07-08
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM.
Acta Crystallogr.,Sect.D, 71, 2015
1DS1
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CRYSTAL STRUCTURE OF CLAVAMINATE SYNTHASE IN COMPLEX WITH FE(II) AND 2-OXOGLUTARATE
Descriptor:CLAVAMINATE SYNTHASE 1, SULFATE ION, FE (II) ION, ...
Authors:Zhang, Z.H., Ren, J., Stammers, D.K., Baldwin, J.E., Harlos, K., Schofield, C.J.
Deposit date:2000-01-06
Release date:2000-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase.
Nat.Struct.Biol., 7, 2000
4WKF
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CRYSTAL STRUCTURE OF HUMAN CHITOTRIOSIDASE-1 CATALYTIC DOMAIN IN COMPLEX WITH CHITOBIOSE (2.5MM) AT 1.10 A RESOLUTION
Descriptor:Chitotriosidase-1, DI(N-ACETYL-D-GLUCOSAMINE)
Authors:Fadel, F., Zhao, Y., Cachau, R., Cousido-Siah, A., Ruiz, F.X., Harlos, K., Howard, E., Mitschler, A., Podjarny, A.
Deposit date:2014-10-02
Release date:2015-07-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.101 Å)
Cite:New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM.
Acta Crystallogr.,Sect.D, 71, 2015
4WK9
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CRYSTAL STRUCTURE OF HUMAN CHITOTRIOSIDASE-1 CATALYTIC DOMAIN IN COMPLEX WITH CHITOBIOSE (0.3MM) AT 1.10 A RESOLUTION
Descriptor:Chitotriosidase-1, DI(N-ACETYL-D-GLUCOSAMINE)
Authors:Fadel, F., Zhao, Y., Cachau, R., Cousido-Siah, A., Ruiz, F.X., Harlos, K., Howard, E., Mitschler, A., Podjarny, A.
Deposit date:2014-10-02
Release date:2015-07-08
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.102 Å)
Cite:New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM.
Acta Crystallogr.,Sect.D, 71, 2015
5OUO
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STRUCTURE OF TGPLP1 APCBETA DOMAIN
Descriptor:Perforin-like protein 1, MAGNESIUM ION, CHLORIDE ION
Authors:Ni, T., Gilbert, R.J.C.
Deposit date:2017-08-24
Release date:2018-04-11
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Structures of monomeric and oligomeric forms of theToxoplasma gondiiperforin-like protein 1.
Sci Adv, 4, 2018
1ODM
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ANAEROBIC AC-VINYLGLYCINE FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VINYLGLYCINE, SULFATE ION, ...
Authors:Elkins, J.M., Rutledge, P.J., Burzlaff, N.I., Clifton, I.J., Adlington, R.M., Roach, P.L., Baldwin, J.E.
Deposit date:2003-02-19
Release date:2003-06-19
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Crystallographic Studies on the Reaction of Isopenicillin N Synthase with an Unsaturated Substrate Analogue
Org.Biomol.Chem., 1, 2003
2UUY
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STRUCTURE OF A TICK TRYPTASE INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN
Descriptor:CATIONIC TRYPSIN, TRYPTASE INHIBITOR, CALCIUM ION, ...
Authors:Siebold, C., Paesen, G.C., Harlos, K., Peacey, M.F., Nuttall, P.A., Stuart, D.I.
Deposit date:2007-03-08
Release date:2007-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:A Tick Protein with a Modified Kunitz Fold Inhibits Human Tryptase.
J.Mol.Biol., 368, 2007
2JJU
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STRUCTURE OF HUMAN SIGNAL REGULATORY PROTEIN (SIRP) BETA
Descriptor:SIGNAL REGULATORY PROTEIN BETA-1, CHLORIDE ION, SULFATE ION
Authors:Hatherley, D., Graham, S.C., Turner, J., Harlos, K., Stuart, D.I., Barclay, A.N.
Deposit date:2008-04-22
Release date:2008-08-05
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47.
Mol.Cell, 31, 2008
1QFT
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HISTAMINE BINDING PROTEIN FROM FEMALE BROWN EAR RHIPICEPHALUS APPENDICULATUS
Descriptor:PROTEIN (FEMALE-SPECIFIC HISTAMINE BINDING PROTEIN 2), HISTAMINE
Authors:Paesen, G.C., Adams, P.L., Harlos, K., Nuttal, P.A., Stuart, D.I.
Deposit date:1999-04-14
Release date:2000-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Tick histamine-binding proteins: isolation, cloning, and three-dimensional structure.
Mol.Cell, 3, 1999
6GBI
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WNT SIGNALLING
Descriptor:Ly6/PLAUR domain-containing protein 6, N-ACETYL-D-GLUCOSAMINE, GLYCEROL, ...
Authors:Zhao, Y., Jones, E.Y.
Deposit date:2018-04-14
Release date:2018-08-15
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structure of the Wnt signaling enhancer LYPD6 and its interactions with the Wnt coreceptor LRP6.
FEBS Lett., 592, 2018
3ZN4
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VP16, A CAPSID PROTEIN OF BACTERIOPHAGE P23-77 (VP16-TYPE-2)
Descriptor:VP16, CITRIC ACID, CHLORIDE ION
Authors:Rissanen, I., Grimes, J.M., Pawlowski, A., Mantynen, S., Harlos, K., Bamford, J.K.H., Stuart, D.I.
Deposit date:2013-02-13
Release date:2013-05-15
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Bacteriophage P23-77 Capsid Protein Structures Reveal the Archetype of an Ancient Branch from a Major Virus Lineage.
Structure, 21, 2013
1BK0
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ACV-FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, SULFATE ION, FE (III) ION, ...
Authors:Roach, P.L., Clifton, I.J., Hensgens, C.M.H., Shibata, N., Schofield, C.J., Hajdu, J., Baldwin, J.E.
Deposit date:1998-07-14
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation.
Nature, 387, 1997
1HB2
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (OXYGEN EXPOSED PRODUCT FROM ANAEROBIC ACOV FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, N6-[(1S)-2-{[(1R)-1-CARBOXY-2-METHYLPROPYL]OXY}-1-(MERCAPTOCARBONYL)-2-OXOETHYL]-6-OXO-L-LYSINE, SULFATE ION, ...
Authors:Ogle, J.M., Clifton, I.J., Rutledge, P.J., Elkins, J.M., Burzlaff, N.I., Adlington, R.M., Roach, P.L., Baldwin, J.E.
Deposit date:2001-04-11
Release date:2001-11-23
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Alternative Oxidation by Isopenicillin N Synthase Observed by X-Ray Diffraction.
Chem.Biol., 8, 2001
2IVI
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ANAEROBIC AC- METHYL-CYCLOPROPYLGLYCINE FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHETASE, D-(L-A-AMINOADIPOYL)-L-CYSTEINYL-B-METHYL-D-CYCLOPROPYLGLYCINE, SULFATE ION, ...
Authors:Elkins, J.M., Howard-Jones, A.R., Clifton, I.J., Roach, P.L., Adlington, R.M., Baldwin, J.E., Rutledge, P.J.
Deposit date:2006-06-13
Release date:2007-04-10
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Interactions of Isopenicillin N Synthase with Cyclopropyl-Containing Substrate Analogues Reveal New Mechanistic Insight.
Biochemistry, 46, 2007
1QJE
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (IP1 - FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, SULFATE ION, ISOPENICILLIN N, ...
Authors:Burzlaff, N.I., Clifton, I.J., Rutledge, P.J., Roach, P.L., Adlington, R.M., Baldwin, J.E.
Deposit date:1999-06-23
Release date:2000-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The Reaction Cycle of Isopenicillin N Synthase Observed by X-Ray Diffraction
Nature, 401, 1999
1UZK
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INTEGRIN BINDING CBEGF22-TB4-CBEGF33 FRAGMENT OF HUMAN FIBRILLIN-1, CA BOUND TO CBEGF23 DOMAIN ONLY
Descriptor:FIBRILLIN-1, CALCIUM ION
Authors:Lee, S.S.J., Knott, V., Harlos, K., Handford, P.A., Stuart, D.I.
Deposit date:2004-03-13
Release date:2006-05-24
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
1QFV
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HISTAMINE BINDING PROTEIN FROM FEMALE BROWN EAR RHIPICEPHALUS APPENDICULATUS
Descriptor:PROTEIN (FEMALE-SPECIFIC HISTAMINE BINDING PROTEIN 2), HISTAMINE
Authors:Paesen, G.C., Adams, P.L., Harlos, K., Nuttal, P.A., Stuart, D.I.
Deposit date:1999-04-14
Release date:2000-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Tick histamine-binding proteins: isolation, cloning, and three-dimensional structure.
Mol.Cell, 3, 1999
1DRY
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CRYSTAL STRUCTURE OF CLAVAMINATE SYNTHASE IN COMPLEX WITH FE(II), 2-OXOGLUTARATE AND N-ALPHA-L-ACETYL ARGININE
Descriptor:CLAVAMINATE SYNTHASE 1, N-ALPHA-L-ACETYL-ARGININE, FE (II) ION, ...
Authors:Zhang, Z.H., Ren, J., Stammers, D.K., Baldwin, J.E., Harlos, K., Schofield, C.J.
Deposit date:2000-01-06
Release date:2000-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase.
Nat.Struct.Biol., 7, 2000
1GP0
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HUMAN IGF2R DOMAIN 11
Descriptor:CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR, SULFATE ION
Authors:Brown, J., Esnouf, R.M., Jones, M.A., Linnell, J., Harlos, K., Hassan, A.B., Jones, E.Y.
Deposit date:2001-10-29
Release date:2002-02-28
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of a Functional Igf2R Fragment Determined from the Anomalous Scattering of Sulfur
Embo J., 21, 2002
1HB3
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (OXYGEN EXPOSED PRODUCT FROM ANAEROBIC ACOV FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, N6-[(1S)-2-{[(1R)-1-CARBOXY-2-METHYLPROPYL]OXY}-1-(MERCAPTOCARBONYL)-2-OXOETHYL]-6-OXO-L-LYSINE, SULFATE ION, ...
Authors:Ogle, J.M., Clifton, I.J., Rutledge, P.J., Elkins, J.M., Burzlaff, N.I., Adlington, R.M., Roach, P.L., Baldwin, J.E.
Deposit date:2001-04-11
Release date:2001-11-23
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Alternative Oxidation by Isopenicillin N Synthase Observed by X-Ray Diffraction.
Chem.Biol., 8, 2001
1QJF
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (MONOCYCLIC SULFOXIDE - FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, SULFATE ION, 1-[(1S)-CARBOXY-2-(METHYLSULFINYL)ETHYL]-(3R)-[(5S)-5-AMINO-5-CARBOXYPENTANAMIDO]-(4R)-SULFANYLAZETIDIN-2-ONE, ...
Authors:Rutledge, P.J., Clifton, I.J., Burzlaff, N.I., Roach, P.L., Adlington, R.M., Baldwin, J.E.
Deposit date:1999-06-23
Release date:2000-06-29
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Reaction Cycle of Isopenicillin N Synthase Observed by X-Ray Diffraction
Nature, 401, 1999