5ADY | | CRYO-EM STRUCTURES OF THE 50S RIBOSOME SUBUNIT BOUND WITH HFLX | | Descriptor: | 50S RIBOSOMAL PROTEIN L32, 50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, ... | | Authors: | Zhang, Y., Mandava, C.S., Cao, W., Li, X., Zhang, D., Li, N., Zhang, Y., Zhang, X., Qin, Y., Mi, K., Lei, J., Sanyal, S., Gao, N. | | Deposit date: | 2015-08-25 | | Release date: | 2015-10-14 | | Last modified: | 2018-10-24 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Hflx is a Ribosome Splitting Factor Rescuing Stalled Ribosomes Under Stress Conditions
Nat.Struct.Mol.Biol., 22, 2015
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3OMW | | CRYSTAL STRUCTURE OF SSU72, AN ESSENTIAL EUKARYOTIC PHOSPHATASE SPECIFIC FOR THE C-TERMINAL DOMAIN OF RNA POLYMERASE II | | Descriptor: | CG14216 | | Authors: | Zhang, Y., Zhang, M., Zhang, Y. | | Deposit date: | 2010-08-27 | | Release date: | 2011-01-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.8701 Å) | | Cite: | Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue.
Biochem.J., 434, 2011
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3OMX | | CRYSTAL STRUCTURE OF SSU72 WITH VANADATE COMPLEX | | Descriptor: | CG14216, VANADATE ION | | Authors: | Zhang, Y., Zhang, M., Zhang, Y. | | Deposit date: | 2010-08-27 | | Release date: | 2011-01-19 | | Last modified: | 2014-10-08 | | Method: | X-RAY DIFFRACTION (2.3366 Å) | | Cite: | Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue.
Biochem.J., 434, 2011
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1THD | | COMPLEX ORGANIZATION OF DENGUE VIRUS E PROTEIN AS REVEALED BY 9.5 ANGSTROM CRYO-EM RECONSTRUCTION | | Descriptor: | Major envelope protein E | | Authors: | Zhang, Y., Zhang, W., Ogata, S., Clements, D., Strauss, J.H., Baker, T.S., Kuhn, R.J., Rossmann, M.G. | | Deposit date: | 2004-06-01 | | Release date: | 2004-09-28 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (9.5 Å) | | Cite: | Conformational changes of the flavivirus e glycoprotein
Structure, 12, 2004
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3ZEE | | ELECTRON CYRO-MICROSCOPY HELICAL RECONSTRUCTION OF PAR-3 N TERMINAL DOMAIN | | Descriptor: | PARTITIONING DEFECTIVE 3 HOMOLOG | | Authors: | Zhang, Y., Wang, W., Chen, J., Zhang, K., Gao, F., Gong, W., Zhang, M., Sun, F., Feng, W. | | Deposit date: | 2012-12-05 | | Release date: | 2013-10-16 | | Last modified: | 2017-08-30 | | Method: | ELECTRON MICROSCOPY (6.1 Å) | | Cite: | Structural Insights Into the Intrinsic Self-Assembly of Par-3 N-Terminal Domain.
Structure, 21, 2013
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4KM8 | | CRYSTAL STRUCTURE OF SUFUD60 | | Descriptor: | Suppressor of fused homolog | | Authors: | Zhang, Y., Qi, X., Zhang, Z., Wu, G. | | Deposit date: | 2013-05-08 | | Release date: | 2013-11-20 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun, 4, 2013
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4KM9 | |
4KMA | |
4KMD | | CRYSTAL STRUCTURE OF SUFUD60-GLI1P | | Descriptor: | Sufu, Zinc finger protein GLI1, GLYCEROL, ... | | Authors: | Zhang, Y., Qi, X., Zhang, Z., Wu, G. | | Deposit date: | 2013-05-08 | | Release date: | 2013-11-20 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun, 4, 2013
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4KMH | |
5E00 | | STRUCTURE OF HLA-A2 P130 | | Descriptor: | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ... | | Authors: | Zhang, Y., Wu, Y., Qi, J., Liu, J., Gao, G.F., Meng, S. | | Deposit date: | 2015-09-26 | | Release date: | 2017-01-18 | | Last modified: | 2019-01-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress.
J. Virol., 92, 2018
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5WSH | | STRUCTURE OF HLA-A2 P130 | | Descriptor: | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ... | | Authors: | Zhang, Y., Wu, Y., Qi, J., Liu, J., Gao, G.F., Meng, S. | | Deposit date: | 2016-12-07 | | Release date: | 2017-12-20 | | Last modified: | 2019-01-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress.
J. Virol., 92, 2018
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6J1L | | CRYSTAL STRUCTURE ANALYSIS OF THE ROR GAMMA(C455E) | | Descriptor: | Nuclear receptor ROR-gamma, 2-[4-(ethylsulfonyl)phenyl]-N-[2'-fluoro-4'-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)[1,1'-biphenyl]-4-yl]acetamide | | Authors: | zhang, Y., Li, C.C., wu, X.S. | | Deposit date: | 2018-12-28 | | Release date: | 2019-05-01 | | Last modified: | 2019-08-28 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable ROR gamma Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer.
J.Med.Chem., 62, 2019
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1N6G | | THE STRUCTURE OF IMMATURE DENGUE-2 PRM PARTICLES | | Descriptor: | major envelope protein E | | Authors: | Zhang, Y., Corver, J., Chipman, P.R., Zhang, W., Pletnev, S.V., Sedlak, D., Baker, T.S., Strauss, J.H., Kuhn, R.J., Rossmann, M.G. | | Deposit date: | 2002-11-10 | | Release date: | 2003-06-03 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (16 Å) | | Cite: | Structures of Immature flavivirus particles
EMBO J., 22, 2003
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1NA4 | | THE STRUCTURE OF IMMATURE YELLOW FEVER VIRUS PARTICLE | | Descriptor: | major envelope protein E | | Authors: | Zhang, Y., Corver, J., Chipman, P.R., Lenches, E., Zhang, W., Pletnev, S.V., Sedlak, D., Baker, T.S., Strauss, J.H., Kuhn, R.J., Rossmann, M.G. | | Deposit date: | 2002-11-26 | | Release date: | 2003-12-09 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY | | Cite: | Structures of immature flavivirus particles
EMBO J., 22, 2003
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1TG8 | | THE STRUCTURE OF DENGUE VIRUS E GLYCOPROTEIN | | Descriptor: | envelope glycoprotein, 2-acetamido-2-deoxy-alpha-D-glucopyranose | | Authors: | Zhang, Y., Zhang, W., Ogata, S., Clements, D., Strauss, J.H., Baker, T.S., Rossmann, M.G. | | Deposit date: | 2004-05-28 | | Release date: | 2004-09-28 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Conformational changes of the flavivirus e glycoprotein
Structure, 12, 2004
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1TGE | | THE STRUCTURE OF IMMATURE DENGUE VIRUS AT 12.5 ANGSTROM | | Descriptor: | envelope glycoprotein | | Authors: | Zhang, Y., Zhang, W., Ogata, S., Clements, D., Strauss, J.H., Baker, T.S., Kuhn, R.J., Rossmann, M.G. | | Deposit date: | 2004-05-28 | | Release date: | 2004-09-28 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (12.5 Å) | | Cite: | Conformational changes of the flavivirus e glycoprotein.
Structure, 12, 2004
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1VZU | | ROLES OF ACTIVE SITE TRYPTOPHANS IN SUBSTRATE BINDING AND CATALYSIS BY ALPHA-1,3 GALACTOSYLTRANSFERASE | | Descriptor: | N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, MANGANESE (II) ION, ... | | Authors: | Zhang, Y., Deshpande, A., Xie, Z., Natesh, R., Acharya, K.R., Brew, K. | | Deposit date: | 2004-05-27 | | Release date: | 2004-07-08 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase.
Glycobiology, 14, 2004
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1VZX | | ROLES OF ACTIVE SITE TRYPTOPHANS IN SUBSTRATE BINDING AND CATALYSIS BY ALPHA-1,3 GALACTOSYLTRANSFERASE | | Descriptor: | N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MANGANESE (II) ION, ... | | Authors: | Zhang, Y., Deshpande, A., Xie, Z., Natesh, R., Acharya, K.R., Brew, K. | | Deposit date: | 2004-05-28 | | Release date: | 2004-07-08 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase.
Glycobiology, 14, 2004
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3TKZ | | STRUCTURE OF THE SHP-2 N-SH2 DOMAIN IN A 1:2 COMPLEX WITH RVIPYFVPLNR PEPTIDE | | Descriptor: | Tyrosine-protein phosphatase non-receptor type 11, PROTEIN (RVIpYFVPLNR peptide) | | Authors: | Zhang, Y., Zhang, J., Yuan, C., Hard, R.L., Park, I.H., Li, C., Bell, C.E., Pei, D. | | Deposit date: | 2011-08-29 | | Release date: | 2011-10-26 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain.
Biochemistry, 50, 2011
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3TL0 | | STRUCTURE OF SHP2 N-SH2 DOMAIN IN COMPLEX WITH RLNPYAQLWHR PEPTIDE | | Descriptor: | Tyrosine-protein phosphatase non-receptor type 11, RLNpYAQLWHR peptide, SULFATE ION | | Authors: | Zhang, Y., Zhang, J., Yuan, C., Hard, R.L., Park, I.H., Li, C., Bell, C.E., Pei, D. | | Deposit date: | 2011-08-29 | | Release date: | 2011-09-28 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain.
Biochemistry, 50, 2011
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5BW0 | | THE CRYSTAL STRUCTURE OF MINOR PSEUDOPILIN BINARY COMPLEX OF XCPV AND XCPW FROM THE TYPE 2 SECRETION SYSTEM OF PSEUDOMONAS AERUGINOSA | | Descriptor: | Type II secretion system protein J, Type II secretion system protein I, SULFATE ION | | Authors: | Zhang, Y., Faucher, F., Poole, K., Jia, Z. | | Deposit date: | 2015-06-05 | | Release date: | 2016-07-20 | | Last modified: | 2020-01-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudomonas aeruginosa.
PLoS Pathog., 14, 2018
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6MG8 | | STRUCTURAL BASIS FOR CHOLESTEROL TRANSPORT-LIKE ACTIVITY OF THE HEDGEHOG RECEPTOR PATCHED | | Descriptor: | Protein patched homolog 1, UNKNOWN LIGAND | | Authors: | Zhang, Y., Bulkley, D., Xin, Y., Roberts, K.J., Asarnow, D.E., Sharma, A., Myers, B.R., Cho, W., Cheng, Y., Beachy, P.A. | | Deposit date: | 2018-09-13 | | Release date: | 2018-11-28 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched.
Cell, 175, 2018
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1FBC | | CRYSTALLOGRAPHIC STUDIES OF THE CATALYTIC MECHANISM OF THE NEUTRAL FORM OF FRUCTOSE-1,6-BISPHOSPHATASE | | Descriptor: | FRUCTOSE 1,6-BISPHOSPHATASE, MAGNESIUM ION, 2,5-anhydro-1,6-di-O-phosphono-D-glucitol | | Authors: | Zhang, Y., Liang, J.-Y., Huang, S., Ke, H., Lipscomb, W.N. | | Deposit date: | 1992-10-14 | | Release date: | 1993-10-31 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystallographic studies of the catalytic mechanism of the neutral form of fructose-1,6-bisphosphatase.
Biochemistry, 32, 1993
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1FBD | | CRYSTALLOGRAPHIC STUDIES OF THE CATALYTIC MECHANISM OF THE NEUTRAL FORM OF FRUCTOSE-1,6-BISPHOSPHATASE | | Descriptor: | FRUCTOSE 1,6-BISPHOSPHATASE, MANGANESE (II) ION, 2,5-anhydro-1,6-di-O-phosphono-D-glucitol | | Authors: | Zhang, Y., Liang, J.-Y., Huang, S., Ke, H., Lipscomb, W.N. | | Deposit date: | 1992-10-16 | | Release date: | 1993-10-31 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystallographic studies of the catalytic mechanism of the neutral form of fructose-1,6-bisphosphatase.
Biochemistry, 32, 1993
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