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4MYG
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BU of 4myg by Molmil
MAPK13, active form
Descriptor: Mitogen-activated protein kinase 13
Authors:Yurtsever, Z, Brett, T.J, Scheaffer, S.M.
Deposit date:2013-09-27
Release date:2015-03-25
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:The crystal structure of phosphorylated MAPK13 reveals common structural features and differences in p38 MAPK family activation.
Acta Crystallogr.,Sect.D, 71, 2015
5WFN
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BU of 5wfn by Molmil
Revised model of leiomodin 2-mediated actin regulation (alternate refinement of PDB 4RWT)
Descriptor: Actin-5C, Leiomodin-2, MAGNESIUM ION, ...
Authors:Yurtsever, Z, Eck, M.J, Dominguez, R.
Deposit date:2017-07-12
Release date:2017-08-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of leiomodin 2 in complex with actin: a structural and functional reexamination
Biophys.J., 113, 2017
5EKO
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BU of 5eko by Molmil
Crystal structure of MAPK13 complex with inhibitor
Descriptor: 3-(4-methyl-1H-imidazol-1-yl)-N-[4-(pyridin-4-yloxy)phenyl]benzamide, Mitogen-activated protein kinase 13
Authors:Brett, T.J, Miller, C.A, Yurtsever, Z.
Deposit date:2015-11-03
Release date:2016-07-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes.
Biochim.Biophys.Acta, 1860, 2016
5EKN
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BU of 5ekn by Molmil
Crystal structure of MAPK13 complex with inhibitor
Descriptor: 1-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-3-[4-(pyridin-4-ylsulfanyl)phenyl]urea, Mitogen-activated protein kinase 13
Authors:Brett, T.J, Miller, C.A, Yurtsever, Z.
Deposit date:2015-11-03
Release date:2016-07-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes.
Biochim.Biophys.Acta, 1860, 2016
4YNO
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BU of 4yno by Molmil
Crystal structure of MAPK13 at INACTIVE FORM
Descriptor: Mitogen-activated protein kinase 13
Authors:Miller, C.A, Brett, T.J.
Deposit date:2015-03-10
Release date:2015-04-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
J.Clin.Invest., 122, 2012

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