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Engineered Extrahelical Base Destabilization Enhances Sequence Discrimination of DNA Methyltransferase M.HhaI
Descriptor:	5'-D(TGPAPTPAPGPCPGPCPTPAPTP*C)-3', Modification methylase HhaI, S-ADENOSYL-L-HOMOCYSTEINE
Authors:	Youngblood, B, Shieh, F.K, De Los Rios, S, Perona, J.J, Reich, N.O.
Deposit date:	2006-09-05
Release date:	2006-10-10
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	Engineered Extrahelical Base Destabilization Enhances Sequence Discrimination of DNA Methyltransferase M.HhaI J.Mol.Biol., 362, 2006

S-Adenosyl-L-methionine-Dependent Methyl Transfer: Observable Precatalytic Intermediates during DNA Cytosine Methylation
Descriptor:	DNA (5'-D(DGPDAPDTPDAPDGPDCPDGPDCPDTPDAPDTPDC)-3'), DNA (5'-D(DTPDGPDAPDTPDAPDGPDCPDGPDCPDTPDAPDTP*DC)-3'), Modification methylase HhaI, ...
Authors:	Shieh, F.K.
Deposit date:	2007-07-25
Release date:	2007-08-21
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2.88 Å)
Cite:	S-Adenosyl-l-methionine-Dependent Methyl Transfer: Observable Precatalytic Intermediates during DNA Cytosine Methylation Biochemistry, 46, 2007

Ternary structure of Arg165Ala M.HhaI C5-Cytosine DNA methyltransferase with unmodified DNA and AdoHcy
Descriptor:	2'-DEOXYCYTIDINE, DNA (5'-D(DGPDAPDTPDAPDGPDCPDGPDCPDTPDAPDTPDC)-3'), DNA (5'-D(DGPDCPDTPDAPDTPDC)-3'), ...
Authors:	Shieh, F.K.
Deposit date:	2007-08-08
Release date:	2007-08-28
Last modified:	2021-11-10
Method:	X-RAY DIFFRACTION (2.79 Å)
Cite:	The role of Arg165 towards base flipping, base stabilization and catalysis in M.HhaI J.Mol.Biol., 362, 2006

Ternary structure of WT M.HhaI C5-Cytosine DNA methyltransferase with unmodified DNA and AdoHcy
Descriptor:	5'-D(GPAPTPAPGPCPGPCPTPAPTPC)-3', 5'-D(TPGPAPTPAPGPCPGPCPTPAPTP*C)-3', Modification methylase HhaI, ...
Authors:	Shieh, F.
Deposit date:	2006-07-19
Release date:	2006-09-19
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.96 Å)
Cite:	The Role of Arg165 Towards Base Flipping, Base Stabilization and Catalysis in M.HhaI. J.Mol.Biol., 362, 2006