3BD9 | | HUMAN 3-O-SULFOTRANSFERASE ISOFORM 5 WITH BOUND PAP | | Descriptor: | Heparan sulfate glucosamine 3-O-sulfotransferase 5, ADENOSINE-3'-5'-DIPHOSPHATE | | Authors: | Xu, D., Moon, A.F., Song, D., Liu, J., Pedersen, L.C. | | Deposit date: | 2007-11-14 | | Release date: | 2008-01-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Engineering sulfotransferases to modify heparan sulfate.
Nat.Chem.Biol., 4, 2008
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4IM8 | | LOW RESOLUTION CRYSTAL STRUCTURE OF MOUSE RAGE | | Descriptor: | Advanced glycation end-products receptor | | Authors: | Xu, D., Young, J.H., Krahn, J.M., Song, D., Corbett, K.D., Chazin, W.J., Pedersen, L.C., Esko, J.D. | | Deposit date: | 2013-01-02 | | Release date: | 2013-08-14 | | Last modified: | 2014-02-26 | | Method: | X-RAY DIFFRACTION (3.503 Å) | | Cite: | Stable RAGE-Heparan Sulfate Complexes Are Essential for Signal Transduction.
Acs Chem.Biol., 8, 2013
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1NWB | | SOLUTION NMR STRUCTURE OF PROTEIN AQ_1857 FROM AQUIFEX AEOLICUS: NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET QR6. | | Descriptor: | Hypothetical protein AQ_1857 | | Authors: | Xu, D., Liu, G., Xiao, R., Acton, T., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2003-02-05 | | Release date: | 2003-06-03 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | NMR structure of the hypothetical protein AQ-1857 encoded by the Y157 gene from Aquifex aeolicus reveals a novel protein fold.
Proteins, 54, 2004
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5GWD | | STRUCTURE OF MYROILYSIN | | Descriptor: | Myroilysin, ZINC ION | | Authors: | Xu, D., Ran, T., Wang, W. | | Deposit date: | 2016-09-10 | | Release date: | 2017-02-15 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Myroilysin Is a New Bacterial Member of the M12A Family of Metzincin Metallopeptidases and Is Activated by a Cysteine Switch Mechanism.
J. Biol. Chem., 292, 2017
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6JBJ | | CRYO-EM STRUCTURE OF HUMAN LYSOSOMAL COBALAMIN EXPORTER ABCD4 | | Descriptor: | ATP-binding cassette sub-family D member 4, ADENOSINE-5'-TRIPHOSPHATE | | Authors: | Xu, D., Feng, Z., Hou, W.T., Jiang, Y.L., Wang, L., Sun, L.F., Zhou, C.Z., Chen, Y. | | Deposit date: | 2019-01-25 | | Release date: | 2019-09-11 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structure of human lysosomal cobalamin exporter ABCD4.
Cell Res., 29, 2019
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5CZW | | CRYSTAL STRUCTURE OF MYROILYSIN | | Descriptor: | Myroilysin, ZINC ION | | Authors: | Zhou, J., Ran, T., Xu, D., Wang, W. | | Deposit date: | 2015-08-01 | | Release date: | 2016-08-03 | | Last modified: | 2017-04-26 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Myroilysin is a New Bacterial Member of the M12A Family of Metzincin Metallopeptidases and Activated by a Cysteine-switch Mechanism
J. Biol. Chem., 292, 2017
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5GP7 | | STRUCTURAL BASIS FOR THE BINDING BETWEEN TANKYRASE-1 AND USP25 | | Descriptor: | Tankyrase-1, Ubiquitin carboxyl-terminal hydrolase 25, GLYCEROL | | Authors: | Liu, J., Xu, D., Fu, T., Pan, L. | | Deposit date: | 2016-08-01 | | Release date: | 2017-07-12 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (1.502 Å) | | Cite: | USP25 regulates Wnt signaling by controlling the stability of tankyrases
Genes Dev., 31, 2017
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5Y0E | |
3S1S | | CHARACTERIZATION AND CRYSTAL STRUCTURE OF THE TYPE IIG RESTRICTION ENDONUCLEASE BPUSI | | Descriptor: | restriction endonuclease BpuSI, S-ADENOSYL-L-HOMOCYSTEINE, 1,2-ETHANEDIOL, ... | | Authors: | Shen, B.W., Xu, D., Chan, S.-H., Zheng, Y., Zhu, Y., Xu, S.-Y., Stoddard, B.L. | | Deposit date: | 2011-05-16 | | Release date: | 2011-07-13 | | Last modified: | 2011-10-19 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Characterization and crystal structure of the type IIG restriction endonuclease RM.BpuSI.
Nucleic Acids Res., 39, 2011
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5XNB | |
2HG7 | | SOLUTION NMR STRUCTURE OF PHAGE-LIKE ELEMENT PBSX PROTEIN XKDW, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR355 | | Descriptor: | Phage-like element PBSX protein xkdW | | Authors: | Liu, G., Parish, D., Xu, D., Atreya, H., Sukumaran, D., Ho, C.K., Jiang, M., Cunningham, K., Ma, L.-C., Xiao, R., Liu, J., Baran, M., Swapna, G.V., Acton, T.B., Rost, B., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-06-26 | | Release date: | 2006-08-22 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of Phage-like element PBSX protein xkdW, Northeast Structural Genomics Consortium Target SR355
TO BE PUBLISHED
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2JPU | | SOLUTION STRUCTURE OF NESG TARGET SSR10, ORF C02003 PROTEIN | | Descriptor: | Orf c02003 protein | | Authors: | Wu, Y., Singarapu, K.K., Zhang, Q., Eletski, A., Xu, D., Sukumaran, D., Parish, D., Wang, D., Jiang, M., Cunningham, K., Maglaqui, M., Owens, L., Xiao, R., Liu, J., Baran, M., Swapna, G.V.T., Acton, T., Rost, B., Montelione, G., Szyperski, T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2007-05-23 | | Release date: | 2007-07-03 | | Last modified: | 2020-02-19 | | Method: | SOLUTION NMR | | Cite: | Solution structure of NESG target SsR10, Orf c02003 protein
To be Published
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2JVM | | SOLUTION NMR STRUCTURE OF RHODOBACTER SPHAEROIDES PROTEIN RHOS4_26430. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET RHR95 | | Descriptor: | Uncharacterized protein | | Authors: | Eletsky, A., Sukumaran, D., Zhang, Q., Parish, D., Xu, D., Wang, H., Janjua, H., Owens, L., Xiao, R., Liu, J., Baran, M.C., Swapna, G.V.T., Acton, T.B., Rost, B., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2007-09-21 | | Release date: | 2007-10-16 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of Rhodobacter sphaeroides protein RHOS4_26430.
To be Published
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2HFI | | SOLUTION NMR STRUCTURE OF PROTEIN YPPE FROM BACILLUS SUBTILIS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR213 | | Descriptor: | Hypothetical protein yppE | | Authors: | Liu, G., Singarapu, K.K., Parish, D., Eletsky, A., Xu, D., Sukumaran, D., Ho, C.K., Fang, Y., Cunningham, K., Ma, L.-C., Xiao, R., Liu, J., Baran, M., Swapna, G.V.T., Acton, T.B., Rost, B., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-06-23 | | Release date: | 2006-07-25 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of hypothetical protein yppE: Northeast Structural Genomics Consortium Target SR213
TO BE PUBLISHED
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6P0I | | CRYSTAL STRUCTURE OF GDP-BOUND HUMAN RALA IN A COVALENT COMPLEX WITH ARYL SULFONYL FLUORIDE COMPOUNDS. | | Descriptor: | Ras-related protein Ral-A, GUANOSINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL, ... | | Authors: | Bum-Erdene, K., Gonzalez-Gutierrez, G., Liu, D., Ghozayel, M.K., Xu, D., Meroueh, S.O. | | Deposit date: | 2019-05-17 | | Release date: | 2020-03-04 | | Last modified: | 2020-04-15 | | Method: | X-RAY DIFFRACTION (1.18 Å) | | Cite: | Small-molecule covalent bond formation at tyrosine creates a binding site and inhibits activation of Ral GTPases.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6P0K | | CRYSTAL STRUCTURE OF GDP-BOUND HUMAN RALA IN A COVALENT COMPLEX WITH ARYL SULFONYL FLUORIDE COMPOUNDS. | | Descriptor: | Ras-related protein Ral-A, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Bum-Erdene, K., Gonzalez-Gutierrez, G., Liu, D., Ghozayel, M.K., Xu, D., Meroueh, S.O. | | Deposit date: | 2019-05-17 | | Release date: | 2020-03-04 | | Last modified: | 2020-04-15 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Small-molecule covalent bond formation at tyrosine creates a binding site and inhibits activation of Ral GTPases.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6P0L | | CRYSTAL STRUCTURE OF GDP-BOUND HUMAN RALA IN A COVALENT COMPLEX WITH ARYL SULFONYL FLUORIDE COMPOUNDS. | | Descriptor: | Ras-related protein Ral-A, CALCIUM ION, 4-[(2-methoxypyridin-3-yl)sulfamoyl]benzene-1-sulfonic acid, ... | | Authors: | Bum-Erdene, K., Gonzalez-Gutierrez, G., Liu, D., Ghozayel, M.K., Xu, D., Meroueh, S.O. | | Deposit date: | 2019-05-17 | | Release date: | 2020-03-04 | | Last modified: | 2020-04-15 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Small-molecule covalent bond formation at tyrosine creates a binding site and inhibits activation of Ral GTPases.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6P0M | | CRYSTAL STRUCTURE OF GDP-BOUND HUMAN RALA IN A COVALENT COMPLEX WITH ARYL SULFONYL FLUORIDE COMPOUNDS. | | Descriptor: | Ras-related protein Ral-A, 4-[(3-chloropyridin-2-yl)sulfamoyl]benzene-1-sulfonic acid, CALCIUM ION, ... | | Authors: | Bum-Erdene, K., Gonzalez-Gutierrez, G., Liu, D., Ghozayel, M.K., Xu, D., Meroueh, S.O. | | Deposit date: | 2019-05-17 | | Release date: | 2020-03-04 | | Last modified: | 2020-04-15 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Small-molecule covalent bond formation at tyrosine creates a binding site and inhibits activation of Ral GTPases.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6P0N | | CRYSTAL STRUCTURE OF GDP-BOUND HUMAN RALA IN A COVALENT COMPLEX WITH ARYL SULFONYL FLUORIDE COMPOUNDS. | | Descriptor: | Ras-related protein Ral-A, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Bum-Erdene, K., Gonzalez-Gutierrez, G., Liu, D., Ghozayel, M.K., Xu, D., Meroueh, S.O. | | Deposit date: | 2019-05-17 | | Release date: | 2020-03-04 | | Last modified: | 2020-04-15 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Small-molecule covalent bond formation at tyrosine creates a binding site and inhibits activation of Ral GTPases.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6P0O | | CRYSTAL STRUCTURE OF GDP-BOUND HUMAN RALA | | Descriptor: | Ras-related protein Ral-A, GUANOSINE-5'-DIPHOSPHATE, CALCIUM ION | | Authors: | Bum-Erdene, K., Gonzalez-Gutierrez, G., Liu, D., Ghozayel, M.K., Xu, D., Meroueh, S.O. | | Deposit date: | 2019-05-17 | | Release date: | 2020-03-04 | | Last modified: | 2020-04-15 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Small-molecule covalent bond formation at tyrosine creates a binding site and inhibits activation of Ral GTPases.
Proc.Natl.Acad.Sci.USA, 117, 2020
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1PUZ | | SOLUTION NMR STRUCTURE OF PROTEIN NMA1147 FROM NEISSERIA MENINGITIDIS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET MR19 | | Descriptor: | conserved hypothetical protein | | Authors: | Liu, G., Xu, D., Sukumaran, D.K., Chiang, Y., Acton, T., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2003-06-25 | | Release date: | 2004-06-29 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | NMR structure of the hypothetical protein NMA1147 from Neisseria meningitidis reveals a distinct 5-helix bundle.
Proteins, 55, 2004
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2GZO | | NMR STRUCTURE OF UPF0301 PROTEIN SO3346 FROM SHEWANELLA ONEIDENSIS: NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SOR39 | | Descriptor: | UPF0301 protein SO3346 | | Authors: | Singarapu, K.K., Liu, G., Eletsky, A., Xu, D., Sukumaran, D.K., Mei, J., Xiao, R., Cunningham, K., Ma, L.C., Ritu, S., Acton, T.B., Rost, B., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-05-11 | | Release date: | 2006-06-20 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | NMR structure of UPF0301 PROTEIN SO3346 from Shewanella oneidensis: Northeast Structural Genomics Consortium target SOR39
To be Published
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2HI6 | | SOLUTION NMR STRUCTURE OF UPF0107 PROTEIN AF_0055, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET GR101 | | Descriptor: | UPF0107 protein AF0055 | | Authors: | Liu, G., Atreya, H., Xu, D., Sukumaran, D.K., Chen, C.X., Janjua, H., Cunningham, K., Ma, L.-C., Xiao, R., Liu, J., Baran, M., Swapna, G.V.T., Acton, T.B., Rost, B., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-06-29 | | Release date: | 2006-08-29 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of UPF0107 protein AF_0055, Northeast Structural Genomics Consortium Target GR101 (CASP Target)
To be Published
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2K71 | | STRUCTURE AND DYNAMICS OF A DNA GNRA HAIRPIN SOLVED VY HIGH-SENSITIVITY NMR WITH TWO INDEPENDENT CONVERGING METHODS, SIMULATED ANNEALING (DYANA) AND MESOSCOPIC MOLECULAR MODELLING (BCE/AMBER) | | Descriptor: | 5'-D(*DGP*DCP*DGP*DAP*DAP*DAP*DGP*DC)-3' | | Authors: | Santini, G.P.H., Cognet, J.A.H., Xu, D., Singarapu, K.K., Herve du Penhoat, C.L.M. | | Deposit date: | 2008-07-29 | | Release date: | 2009-07-21 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Nucleic acid folding determined by mesoscale modeling and NMR spectroscopy: solution structure of d(GCGAAAGC).
J.Phys.Chem.B, 113, 2009
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3F5F | | CRYSTAL STRUCTURE OF HEPARAN SULFATE 2-O-SULFOTRANSFERASE FROM GALLUS GALLUS AS A MALTOSE BINDING PROTEIN FUSION. | | Descriptor: | Maltose-binding periplasmic protein, Heparan sulfate 2-O-sulfotransferase 1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | | Authors: | Bethea, H.N., Xu, D., Liu, J., Pedersen, L.C. | | Deposit date: | 2008-11-03 | | Release date: | 2008-12-16 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Redirecting the substrate specificity of heparan sulfate 2-O-sulfotransferase by structurally guided mutagenesis.
Proc.Natl.Acad.Sci.USA, 105, 2008
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