Author results

6ANF
  • Download 6anf
  • View 6anf
Molmil generated image of 6anf
DESIGN OF A SHORT THERMO-STABLE ALPHA-HELIX EMBEDDED IN A MACROCYCLE
Descriptor:Capped-strapped peptide, 3,3'-dimethyl-1,1'-biphenyl
Authors:Wu, H., Acharyya, A., Wu, Y., Liu, L., Jo, H., Gai, F., DeGrado, W.F.
Deposit date:2017-08-13
Release date:2018-02-21
Last modified:2018-05-16
Method:SOLUTION NMR
Cite:Design of a Short Thermally Stable alpha-Helix Embedded in a Macrocycle.
Chembiochem, 19, 2018
6B17
  • Download 6b17
  • View 6b17
Molmil generated image of 6b17
DESIGN OF A SHORT THERMALLY STABLE ALPHA-HELIX EMBEDDED IN A MACROCYCLE
Descriptor:Capped-strapped peptide, AMINO GROUP, 3,3'-dimethyl-1,1'-biphenyl
Authors:Wu, H., Acharyya, A., Wu, Y., Liu, L., Jo, H., Gai, F., DeGrado, W.F.
Deposit date:2017-09-17
Release date:2018-02-21
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Design of a Short Thermally Stable alpha-Helix Embedded in a Macrocycle.
Chembiochem, 19, 2018
2CAS
  • Download 2cas
  • View 2cas
Molmil generated image of 2cas
THE CANINE PARVOVIRUS EMPTY CAPSID STRUCTURE
Descriptor:CANINE PARVOVIRUS EMPTY CAPSID (STRAIN D) VIRAL PROTEIN 2
Authors:Wu, H., Rossmann, M.G.
Deposit date:1993-08-24
Release date:1994-01-31
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:The canine parvovirus empty capsid structure.
J.Mol.Biol., 233, 1993
1HCN
  • Download 1hcn
  • View 1hcn
Molmil generated image of 1hcn
STRUCTURE OF HUMAN CHORIONIC GONADOTROPIN AT 2.6 ANGSTROMS RESOLUTION FROM MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN
Descriptor:HUMAN CHORIONIC GONADOTROPIN, N-ACETYL-D-GLUCOSAMINE
Authors:Wu, H., Lustbader, J.W., Liu, Y., Canfield, R.E., Hendrickson, W.A.
Deposit date:1994-07-01
Release date:1994-09-30
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of human chorionic gonadotropin at 2.6 A resolution from MAD analysis of the selenomethionyl protein.
Structure, 2, 1994
6IDE
  • Download 6ide
  • View 6ide
Molmil generated image of 6ide
CRYSTAL STRUCTURE OF THE VIBRIO CHOLERA VQMA-LIGAND-DNA COMPLEX PROVIDES MOLECULAR MECHANISMS FOR DRUG DESIGN
Descriptor:Transcriptional regulator LuxR family, DNA (5'-D(*AP*GP*GP*GP*GP*GP*GP*AP*AP*AP*TP*CP*CP*CP*CP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*GP*GP*GP*GP*AP*TP*TP*TP*CP*CP*CP*CP*CP*CP*T)-3'), ...
Authors:Wu, H., Li, M.J., Guo, H.J., Zhou, H., Li, B., Xu, Q., Xu, C.Y., Yu, F., He, J.H.
Deposit date:2018-09-09
Release date:2019-01-16
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Crystal structure of theVibrio choleraeVqmA-ligand-DNA complex provides insight into ligand-binding mechanisms relevant for drug design.
J. Biol. Chem., 294, 2019
2P0W
  • Download 2p0w
  • View 2p0w
Molmil generated image of 2p0w
HUMAN HISTONE ACETYLTRANSFERASE 1 (HAT1)
Descriptor:Histone acetyltransferase type B catalytic subunit, Histone peptide H4, ACETATE ION, ...
Authors:Wu, H., Min, J., Zeng, H., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2007-03-01
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of human histone acetyltransferase 1 (HAT1) in complex with acetylcoenzyme A and histone peptide H4
To be Published
5UNA
  • Download 5una
  • View 5una
Molmil generated image of 5una
FRAGMENT OF 7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME
Descriptor:7SK snRNA methylphosphate capping enzyme, unidentified peptide section/fragment, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Wu, H., Tempel, W., Dombrovski, L., McCarthy, A.A., Loppnau, P., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2017-01-30
Release date:2017-03-08
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Fragment of 7SK snRNA methylphosphate capping enzyme
To Be Published
1CDJ
  • Download 1cdj
  • View 1cdj
Molmil generated image of 1cdj
STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Myszka, D., Tendian, S.W., Brouillette, C.G., Sweet, R.W., Chaiken, I.M., Hendrickson, W.A.
Deposit date:1996-11-11
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.
Proc.Natl.Acad.Sci.USA, 93, 1996
1CDU
  • Download 1cdu
  • View 1cdu
Molmil generated image of 1cdu
STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4 MUTANT WITH PHE 43 REPLACED BY VAL
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Myszka, D., Tendian, S.W., Brouillette, C.G., Sweet, R.W., Chaiken, I.M., Hendrickson, W.A.
Deposit date:1996-11-11
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.
Proc.Natl.Acad.Sci.USA, 93, 1996
1CDY
  • Download 1cdy
  • View 1cdy
Molmil generated image of 1cdy
STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4 MUTANT WITH GLY 47 REPLACED BY SER
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Myszka, D., Tendian, S.W., Brouillette, C.G., Sweet, R.W., Chaiken, I.M., Hendrickson, W.A.
Deposit date:1996-11-11
Release date:1997-04-01
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.
Proc.Natl.Acad.Sci.USA, 93, 1996
1K4A
  • Download 1k4a
  • View 1k4a
Molmil generated image of 1k4a
STRUCTURE OF AGAA RNA TETRALOOP, NMR, 20 STRUCTURES
Descriptor:5'-R(*GP*GP*UP*UP*CP*AP*GP*AP*AP*GP*AP*AP*CP*C)-3'
Authors:Wu, H., Yang, P.K., Butcher, S.E., Kang, S., Chanfreau, G., Feigon, J.
Deposit date:2001-10-07
Release date:2001-12-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III.
EMBO J., 20, 2001
1K4B
  • Download 1k4b
  • View 1k4b
Molmil generated image of 1k4b
STRUCTURE OF AGUU RNA TETRALOOP, NMR, 20 STRUCTURES
Descriptor:5'-R(*GP*GP*UP*UP*CP*AP*GP*UP*UP*GP*AP*AP*CP*C)-3'
Authors:Wu, H., Yang, P.K., Butcher, S.E., Kang, S., Chanfreau, G., Feigon, J.
Deposit date:2001-10-07
Release date:2001-12-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III.
EMBO J., 20, 2001
1T4L
  • Download 1t4l
  • View 1t4l
Molmil generated image of 1t4l
SOLUTION STRUCTURE OF DOUBLE-STRANDED RNA BINDING DOMAIN OF S. CEREVISIAE RNASE III (RNT1P) IN COMPLEX WITH THE 5' TERMINAL RNA HAIRPIN OF SNR47 PRECURSOR
Descriptor:5' terminal hairpin of snR47 precursor, Ribonuclease III
Authors:Wu, H., Henras, A., Chanfreau, G., Feigon, J.
Deposit date:2004-04-29
Release date:2004-06-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for recognition of the AGNN tetraloop RNA fold by the double-stranded RNA-binding domain of Rnt1p RNase III.
Proc.Natl.Acad.Sci.USA, 101, 2004
1WIO
  • Download 1wio
  • View 1wio
Molmil generated image of 1wio
STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4, TETRAGONAL CRYSTAL FORM
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Kwong, P.D., Hendrickson, W.A.
Deposit date:1996-12-18
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Dimeric association and segmental variability in the structure of human CD4.
Nature, 387, 1997
1WIP
  • Download 1wip
  • View 1wip
Molmil generated image of 1wip
STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4, MONOCLINIC CRYSTAL FORM
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Kwong, P.D., Hendrickson, W.A.
Deposit date:1996-12-18
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Dimeric association and segmental variability in the structure of human CD4.
Nature, 387, 1997
1WIQ
  • Download 1wiq
  • View 1wiq
Molmil generated image of 1wiq
STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4, TRIGONAL CRYSTAL FORM
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Kwong, P.D., Hendrickson, W.A.
Deposit date:1996-12-18
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (5 Å)
Cite:Dimeric association and segmental variability in the structure of human CD4.
Nature, 387, 1997
1XDX
  • Download 1xdx
  • View 1xdx
Molmil generated image of 1xdx
SOLUTION STRUCTURE OF THE TCTEX1 LIGHT CHAIN FROM CHLAMYDOMONAS INNER DYNEIN ARM I1
Descriptor:Tctex1 Light Chain protein
Authors:Wu, H., Maciejewski, M.W., Takebe, S., King, S.M.
Deposit date:2004-09-08
Release date:2005-03-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the Tctex1 Dimer Reveals a Mechanism for Dynein-Cargo Interactions
Structure, 13, 2005
2FJ4
  • Download 2fj4
  • View 2fj4
Molmil generated image of 2fj4
SOLUTION STRUCTURE OF A-DOMAIN OF HUMAN METALLOTHIONEIN-3 (MT-3)
Descriptor:Metallothionein-3, CADMIUM ION
Authors:Wu, H., Zhang, Q.
Deposit date:2005-12-31
Release date:2006-01-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:SOLUTION STRUCTURE OF a-domain of HUMAN Metallothionein-3 (MT-3)
TO BE Published
2FJ5
  • Download 2fj5
  • View 2fj5
Molmil generated image of 2fj5
SOLUTION STRUCTURE OF SOLE A-DOMAIN OF HUMAN METALLOTHIONEIN-3 (MT-3)
Descriptor:Metallothionein-3, CADMIUM ION
Authors:Wu, H., Zhang, Q.
Deposit date:2005-12-31
Release date:2006-01-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:SOLUTION STRUCTURE OF sole a-domain of HUMAN Metallothionein-3 (MT-3)
TO BE PUBLISHED
2MVM
  • Download 2mvm
  • View 2mvm
Molmil generated image of 2mvm
SOLUTION STRUCTURE OF EEF1BDELTA CAR DOMAIN
Descriptor:Elongation factor 1-delta
Authors:Wu, H., Feng, Y.
Deposit date:2014-10-09
Release date:2015-02-04
Last modified:2015-04-15
Method:SOLUTION NMR
Cite:Evolutionarily Conserved Binding of Translationally Controlled Tumor Protein to Eukaryotic Elongation Factor 1B.
J.Biol.Chem., 290, 2015
2MVN
  • Download 2mvn
  • View 2mvn
Molmil generated image of 2mvn
SOLUTION STRUCTURE OF EEF1BDELTA CAR DOMAIN IN TCTP-BOUND STATE
Descriptor:Elongation factor 1-delta
Authors:Wu, H., Feng, Y.
Deposit date:2014-10-09
Release date:2015-02-04
Last modified:2015-04-15
Method:SOLUTION NMR
Cite:Evolutionarily Conserved Binding of Translationally Controlled Tumor Protein to Eukaryotic Elongation Factor 1B.
J.Biol.Chem., 290, 2015
2N51
  • Download 2n51
  • View 2n51
Molmil generated image of 2n51
NMR STRUCTURE OF THE C-TERMINAL REGION OF HUMAN EUKARYOTIC ELONGATION FACTOR 1B
Descriptor:Elongation factor 1-delta
Authors:Wu, H., Feng, Y.
Deposit date:2015-07-02
Release date:2016-05-18
Method:SOLUTION NMR
Cite:The C-terminal region of human eukaryotic elongation factor 1B delta.
J.Biomol.Nmr, 64, 2016
2P89
  • Download 2p89
  • View 2p89
Molmil generated image of 2p89
SOLUTION STRUCTURE OF THE 3' PSEUDOURIDYATION POCKET OF U65 SNORNA WITH BOUND SUBSTRATE
Descriptor:U65 H/ACA snoRNA, 28S rRNA
Authors:Wu, H., Feigon, J.
Deposit date:2007-03-22
Release date:2007-04-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QTF
  • Download 2qtf
  • View 2qtf
Molmil generated image of 2qtf
CRYSTAL STRUCTURE OF A GTP-BINDING PROTEIN FROM THE HYPERTHERMOPHILIC ARCHAEON SULFOLOBUS SOLFATARICUS
Descriptor:GTP-binding protein, CADMIUM ION, SULFATE ION, ...
Authors:Wu, H., Sun, L., Brouns, S.J., Fu, S., Rao, Z., Van der Oost, J.
Deposit date:2007-08-02
Release date:2008-08-19
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus.
To be Published
2QTH
  • Download 2qth
  • View 2qth
Molmil generated image of 2qth
CRYSTAL STRUCTURE OF A GTP-BINDING PROTEIN FROM THE HYPERTHERMOPHILIC ARCHAEON SULFOLOBUS SOLFATARICUS IN COMPLEX WITH GDP
Descriptor:GTP-binding protein, CADMIUM ION, MAGNESIUM ION, ...
Authors:Wu, H., Sun, L., Brouns, S.J., Fu, S., Rao, Z., Van der Oost, J.
Deposit date:2007-08-02
Release date:2008-08-19
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus.
To be Published