1ZVD
| Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT domain | Descriptor: | PHOSPHATE ION, SODIUM ION, Smad ubiquitination regulatory factor 2 | Authors: | Ogunjimi, A.A, Briant, D.J, Pece-Barbara, N, Le Roy, C, Di Guglielmo, G.M, Kavsak, P, Rasmussen, R.K, Seet, B.T, Sicheri, F, Wrana, J.L. | Deposit date: | 2005-06-01 | Release date: | 2005-08-09 | Last modified: | 2011-09-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain. Mol.Cell, 19, 2005
|
|
2DJY
| Solution structure of Smurf2 WW3 domain-Smad7 PY peptide complex | Descriptor: | Mothers against decapentaplegic homolog 7, Smad ubiquitination regulatory factor 2 | Authors: | Chong, P.A, Lin, H, Wrana, J.L, Forman-Kay, J.D. | Deposit date: | 2006-04-06 | Release date: | 2006-05-02 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | An Expanded WW Domain Recognition Motif Revealed by the Interaction between Smad7 and the E3 Ubiquitin Ligase Smurf2. J.Biol.Chem., 281, 2006
|
|
2JQZ
| Solution Structure of the C2 domain of human Smurf2 | Descriptor: | E3 ubiquitin-protein ligase SMURF2 | Authors: | Wiesner, S, Ogunjimi, A.A, Wang, H, Rotin, D, Sicheri, F, Wrana, J.L, Forman-Kay, J.D. | Deposit date: | 2007-06-15 | Release date: | 2007-09-11 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Autoinhibition of the HECT-Type Ubiquitin Ligase Smurf2 through Its C2 Domain Cell(Cambridge,Mass.), 130, 2007
|
|
2KXQ
| Solution Structure of Smurf2 WW2 and WW3 bound to Smad7 PY motif containing peptide | Descriptor: | E3 ubiquitin-protein ligase SMURF2, Smad7 PY motif containing peptide | Authors: | Chong, A, Lin, H, Wrana, J, Forman-Kay, J.D. | Deposit date: | 2010-05-11 | Release date: | 2010-10-13 | Last modified: | 2012-06-20 | Method: | SOLUTION NMR | Cite: | Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity. Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
1DEV
| |
2PJY
| |
3TZM
| TGF-beta Receptor type 1 in complex with SB431542 | Descriptor: | 4-[5-(1,3-benzodioxol-5-yl)-4-(pyridin-2-yl)-1H-imidazol-2-yl]benzamide, TGF-beta receptor type-1 | Authors: | Ogunjimi, A.A, Zeqiraj, E, Ceccarelli, D.F, Sicheri, F. | Deposit date: | 2011-09-27 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis for Specificity of TGFbeta Family Receptor Small Molecule Inhibitors Cell Signal, 24, 2012
|
|
7M3Q
| Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV) | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, ... | Authors: | Chowdhury, A, Singer, A.U, Ogunjimi, A.A, Teyra, J, Zhang, W, Sicheri, F, Sidhu, S.S. | Deposit date: | 2021-03-18 | Release date: | 2021-04-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV) To be published
|
|