2GPL
| TMC-95 based biphenyl-ether macrocycles: specific proteasome inhibitors | Descriptor: | BENZYL [12-(2-AMINO-2-OXOETHYL)-4-NITRO-10,13-DIOXO-15-[(PROPYLAMINO)CARBONYL]-2-OXA-11,14-DIAZATRICYCLO[15 .2.2.1~3,7~]DOCOSA-1(19),3(22),4,6,17,20-HEXAEN-9-YL]CARBAMATE, Proteasome component C1, Proteasome component C11, ... | Authors: | Groll, M, Goetz, M, Kaiser, M, Weyher, E, Moroder, M. | Deposit date: | 2006-04-18 | Release date: | 2006-07-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | TMC-95-Based Inhibitor Design Provides Evidence for the Catalytic Versatility of the Proteasome. Chem.Biol., 13, 2006
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6SYT
| Structure of the SMG1-SMG8-SMG9 complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | Authors: | Gat, Y, Schuller, J.M, Conti, E. | Deposit date: | 2019-10-01 | Release date: | 2019-12-11 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | InsP6binding to PIKK kinases revealed by the cryo-EM structure of an SMG1-SMG8-SMG9 complex. Nat.Struct.Mol.Biol., 26, 2019
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