Author results

1FPI
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FRUCTOSE-1,6-BISPHOSPHATASE (D-FRUCTOSE-1,6-BISPHOSPHATE 1-PHOSPHOHYDROLASE) COMPLEXED WITH AMP, 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE AND POTASSIUM IONS (100 MM)
分子名称:FRUCTOSE-1,6-BISPHOSPHATASE, POTASSIUM ION, ADENOSINE MONOPHOSPHATE, ...
著者Villeret, V., Lipscomb, W.N.
登録日1995-06-02
公開日1996-06-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase.
Proc.Natl.Acad.Sci.USA, 92, 1995
1FPJ
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FRUCTOSE-1,6-BISPHOSPHATASE (D-FRUCTOSE-1,6-BISPHOSPHATE 1-PHOSPHOHYDROLASE) COMPLEXED WITH AMP, 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE, THALLIUM (10 MM) AND LITHIUM IONS (10 MM)
分子名称:FRUCTOSE-1,6-BISPHOSPHATASE, THALLIUM (I) ION, ADENOSINE MONOPHOSPHATE, ...
著者Villeret, V., Lipscomb, W.N.
登録日1995-06-02
公開日1996-06-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase.
Proc.Natl.Acad.Sci.USA, 92, 1995
1FPK
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FRUCTOSE-1,6-BISPHOSPHATASE (D-FRUCTOSE-1,6-BISPHOSPHATE 1-PHOSPHOHYDROLASE) COMPLEXED WITH THALLIUM IONS (10 MM)
分子名称:FRUCTOSE-1,6-BISPHOSPHATASE, THALLIUM (I) ION
著者Villeret, V., Lipscomb, W.N.
登録日1995-06-02
公開日1996-06-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase.
Proc.Natl.Acad.Sci.USA, 92, 1995
1FPL
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FRUCTOSE-1,6-BISPHOSPHATASE (D-FRUCTOSE-1,6-BISPHOSPHATE 1-PHOSPHOHYDROLASE) COMPLEXED WITH AMP, 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE AND THALLIUM IONS (10 MM)
分子名称:FRUCTOSE-1,6-BISPHOSPHATASE, THALLIUM (I) ION, ADENOSINE MONOPHOSPHATE, ...
著者Villeret, V., Lipscomb, W.N.
登録日1995-06-02
公開日1996-06-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase.
Proc.Natl.Acad.Sci.USA, 92, 1995
1A1S
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ORNITHINE CARBAMOYLTRANSFERASE FROM PYROCOCCUS FURIOSUS
分子名称:ORNITHINE CARBAMOYLTRANSFERASE
著者Villeret, V., Clantin, B., Tricot, C., Legrain, C., Roovers, M., Stalon, V., Glansdorff, N., Van Beeumen, J.
登録日1997-12-15
公開日1998-06-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structure of Pyrococcus furiosus ornithine carbamoyltransferase reveals a key role for oligomerization in enzyme stability at extremely high temperatures.
Proc.Natl.Acad.Sci.USA, 95, 1998
1ORT
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ORNITHINE TRANSCARBAMOYLASE FROM PSEUDOMONAS AERUGINOSA
分子名称:ORNITHINE TRANSCARBAMOYLASE
著者Villeret, V., Dideberg, O.
登録日1995-08-24
公開日1996-12-07
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of Pseudomonas aeruginosa catabolic ornithine transcarbamoylase at 3.0-A resolution: a different oligomeric organization in the transcarbamoylase family.
Proc.Natl.Acad.Sci.USA, 92, 1995
1FPD
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STRUCTURAL ASPECTS OF THE ALLOSTERIC INHIBITION OF FRUCTOSE-1,6-BISPHOSPHATASE BY AMP: THE BINDING OF BOTH THE SUBSTRATE ANALOGUE 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE AND CATALYTIC METAL IONS MONITORED BY X-RAY CRYSTALLOGRAPHY
分子名称:FRUCTOSE 1,6-BISPHOSPHATASE, MANGANESE (II) ION, 2,5-ANHYDROGLUCITOL-1,6-BIPHOSPHATE, ...
著者Villeret, V., Huang, S., Zhang, Y., Lipscomb, W.N.
登録日1994-12-15
公開日1995-02-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural aspects of the allosteric inhibition of fructose-1,6-bisphosphatase by AMP: the binding of both the substrate analogue 2,5-anhydro-D-glucitol 1,6-bisphosphate and catalytic metal ions monitored by X-ray crystallography.
Biochemistry, 34, 1995
1FPE
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STRUCTURAL ASPECTS OF THE ALLOSTERIC INHIBITION OF FRUCTOSE-1,6-BISPHOSPHATASE BY AMP: THE BINDING OF BOTH THE SUBSTRATE ANALOGUE 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE AND CATALYTIC METAL IONS MONITORED BY X-RAY CRYSTALLOGRAPHY
分子名称:FRUCTOSE 1,6-BISPHOSPHATASE, MANGANESE (II) ION, 2,5-ANHYDROGLUCITOL-1,6-BIPHOSPHATE, ...
著者Villeret, V., Huang, S., Zhang, Y., Lipscomb, W.N.
登録日1994-12-15
公開日1995-02-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural aspects of the allosteric inhibition of fructose-1,6-bisphosphatase by AMP: the binding of both the substrate analogue 2,5-anhydro-D-glucitol 1,6-bisphosphate and catalytic metal ions monitored by X-ray crystallography.
Biochemistry, 34, 1995
1FPF
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STRUCTURAL ASPECTS OF THE ALLOSTERIC INHIBITION OF FRUCTOSE-1,6-BISPHOSPHATASE BY AMP: THE BINDING OF BOTH THE SUBSTRATE ANALOGUE 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE AND CATALYTIC METAL IONS MONITORED BY X-RAY CRYSTALLOGRAPHY
分子名称:FRUCTOSE 1,6-BISPHOSPHATASE, MANGANESE (II) ION, 2,5-ANHYDROGLUCITOL-1,6-BIPHOSPHATE, ...
著者Villeret, V., Huang, S., Zhang, Y., Lipscomb, W.N.
登録日1994-12-15
公開日1995-02-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural aspects of the allosteric inhibition of fructose-1,6-bisphosphatase by AMP: the binding of both the substrate analogue 2,5-anhydro-D-glucitol 1,6-bisphosphate and catalytic metal ions monitored by X-ray crystallography.
Biochemistry, 34, 1995
1FPG
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STRUCTURAL ASPECTS OF THE ALLOSTERIC INHIBITION OF FRUCTOSE-1,6-BISPHOSPHATASE BY AMP: THE BINDING OF BOTH THE SUBSTRATE ANALOGUE 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE AND CATALYTIC METAL IONS MONITORED BY X-RAY CRYSTALLOGRAPHY
分子名称:FRUCTOSE 1,6-BISPHOSPHATASE, MANGANESE (II) ION, 2,5-ANHYDROGLUCITOL-1,6-BIPHOSPHATE, ...
著者Villeret, V., Huang, S., Zhang, Y., Lipscomb, W.N.
登録日1994-12-15
公開日1995-02-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural aspects of the allosteric inhibition of fructose-1,6-bisphosphatase by AMP: the binding of both the substrate analogue 2,5-anhydro-D-glucitol 1,6-bisphosphate and catalytic metal ions monitored by X-ray crystallography.
Biochemistry, 34, 1995
1SPI
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CRYSTAL STRUCTURE OF SPINACH CHLOROPLAST FRUCTOSE-1,6-BISPHOSPHATASE AT 2.8 ANGSTROMS RESOLUTION
分子名称:FRUCTOSE 1,6-BISPHOSPHATASE
著者Villeret, V., Huang, S., Zhang, Y., Xue, Y., Lipscomb, W.N.
登録日1994-12-14
公開日1995-02-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of spinach chloroplast fructose-1,6-bisphosphatase at 2.8 A resolution.
Biochemistry, 34, 1995
1H71
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PSYCHROPHILIC PROTEASE FROM PSEUDOALTEROMONAS 'TAC II 18'
分子名称:SERRALYSIN, CALCIUM ION, ZINC ION
著者Villeret, V., Van Petegem, F., Aghajari, N., Chessa, J.-P., Gerday, C., Haser, R., Van Beeumen, J.
登録日2001-07-02
公開日2003-02-13
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of a Psychrophilic Metalloprotease Reveal New Insights Into Catalysis by Cold-Adapted Proteases
Proteins: Struct.,Funct., Genet., 50, 2003
3G1L
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ETHR FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH COMPOUND BDM14744
分子名称:TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR, 3-(4-fluorophenyl)-5-phenyl-4H-1,2,4-triazole
著者Willand, N., Dirie, B., Carette, X., Bifani, P., Singhal, A., Desroses, M., Leroux, F., Willery, E., Mathys, V., Deprez-Poulain, R., Delcroix, G., Frenois, F., Aumercier, M., Locht, C., Villeret, V., Deprez, B., Baulard, A.R.
登録日2009-01-30
公開日2009-07-21
最終更新日2014-03-12
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Synthetic EthR inhibitors boost antituberculous activity of ethionamide.
Nat.Med. (N.Y.), 15, 2009
3G1M
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ETHR FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH COMPOUND BDM31381
分子名称:TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR, 1-(thiophen-2-ylacetyl)-4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)piperidine
著者Willand, N., Dirie, B., Carette, X., Bifani, P., Singhal, A., Desroses, M., Leroux, F., Willery, E., Mathys, V., Deprez-Poulain, R., Delcroix, G., Frenois, F., Aumercier, M., Locht, C., Villeret, V., Deprez, B., Baulard, A.R.
登録日2009-01-30
公開日2009-07-21
最終更新日2014-03-12
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Synthetic EthR inhibitors boost antituberculous activity of ethionamide.
Nat.Med. (N.Y.), 15, 2009
3G1O
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ETHR FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH COMPOUND BDM14500
分子名称:TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR, tert-butyl 4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)piperidine-1-carboxylate
著者Willand, N., Dirie, B., Carette, X., Bifani, P., Singhal, A., Desroses, M., Leroux, F., Willery, E., Mathys, V., Deprez-Poulain, R., Delcroix, G., Frenois, F., Aumercier, M., Locht, C., Villeret, V., Deprez, B., Baulard, A.R.
登録日2009-01-30
公開日2009-07-21
最終更新日2014-02-19
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Synthetic EthR inhibitors boost antituberculous activity of ethionamide.
NAT.MED. (N.Y.), 15, 2009
3QPL
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G106W MUTANT OF ETHR FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:HTH-type transcriptional regulator EthR
著者Carette, X., Willery, E., Hoos, S., Lecat-Guillet, N., Frenois, F., Dirie, B., Villeret, V., England, P., Deprez, B., Locht, C., Willand, N., Baulard, A.
登録日2011-02-14
公開日2011-12-28
最終更新日2012-05-09
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands.
Nucleic Acids Res., 40, 2012
1B65
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STRUCTURE OF L-AMINOPEPTIDASE D-ALA-ESTERASE/AMIDASE FROM OCHROBACTRUM ANTHROPI, A PROTOTYPE FOR THE SERINE AMINOPEPTIDASES, REVEALS A NEW VARIANT AMONG THE NTN HYDROLASE FOLD
分子名称:PROTEIN (AMINOPEPTIDASE)
著者Bompard-Gilles, C., Villeret, V., Davies, G.J., Fanuel, L., Joris, B., Frere, J.M., Van Beeumen, J.
登録日1999-01-20
公開日1999-07-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献A new variant of the Ntn hydrolase fold revealed by the crystal structure of L-aminopeptidase D-ala-esterase/amidase from Ochrobactrum anthropi.
Structure Fold.Des., 8, 2000
4QL0
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CRYSTAL STRUCTURE ANALYSIS OF THE MEMBRANE TRANSPORTER FHAC (DOUBLE MUTANT V169T, I176N)
分子名称:Filamentous hemagglutinin transporter protein FhaC, TRIETHYLENE GLYCOL, DI(HYDROXYETHYL)ETHER, ...
著者Maier, T., Clantin, B., Gruss, F., Dewitte, F., Delattre, A.S., Jacob-Dubuisson, F., Hiller, S., Villeret, V.
登録日2014-06-10
公開日2015-06-17
最終更新日2016-12-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Conserved Omp85 lid-lock structure and substrate recognition in FhaC
Nat Commun, 6, 2015
3CQL
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CRYSTAL STRUCTURE OF GH FAMILY 19 CHITINASE FROM CARICA PAPAYA
分子名称:Endochitinase, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, N-ACETYL-D-GLUCOSAMINE, ...
著者Huet, J., Rucktoa, P., Clantin, B., Azarkan, M., Looze, Y., Villeret, V., Wintjens, R.
登録日2008-04-03
公開日2008-08-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献X-ray Structure of Papaya Chitinase Reveals the Substrate Binding Mode of Glycosyl Hydrolase Family 19 Chitinases.
Biochemistry, 47, 2008
2FAW
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CRYSTAL STRUCTURE OF PAPAYA GLUTAMINYL CYCLASE
分子名称:glutamine cyclotransferase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
著者Wintjens, R., Belrhali, H., Clantin, B., Azarkan, M., Bompard, C., Baeyens-Volant, D., Looze, Y., Villeret, V.
登録日2005-12-08
公開日2006-10-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of papaya glutaminyl cyclase, an archetype for plant and bacterial glutaminyl cyclases.
J.Mol.Biol., 357, 2006
4QKY
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CRYSTAL STRUCTURE ANALYSIS OF THE MEMBRANE TRANSPORTER FHAC
分子名称:Filamentous hemagglutinin transporter protein FhaC, PHOSPHATE ION
著者Maier, T., Clantin, B., Gruss, F., Dewitte, F., Delattre, A.S., Jacob-Dubuisson, F., Hiller, S., Villeret, V.
登録日2014-06-10
公開日2014-10-22
最終更新日2016-12-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Conserved Omp85 lid-lock structure and substrate recognition in FhaC
Nat Commun, 6, 2015
5ODD
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HUMAN MED26 N-TERMINAL DOMAIN (1-92)
分子名称:Mediator of RNA polymerase II transcription subunit 26
著者Lens, Z., Cantrelle, F.-X., Perruzini, R., Dewitte, F., Hanoulle, X., Villeret, V., Verger, A., Landrieu, I.
登録日2017-07-05
公開日2017-11-29
最終更新日2019-05-08
実験手法SOLUTION NMR
主引用文献1H, 15N and 13C assignments of the N-terminal domain of the Mediator complex subunit MED26.
Biomol NMR Assign, 10, 2016
1HX3
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CRYSTAL STRUCTURE OF E.COLI ISOPENTENYL DIPHOSPHATE:DIMETHYLALLYL DIPHOSPHATE ISOMERASE
分子名称:ISOPENTENYL DIPHOSPHATE DELTA-ISOMERASE, SULFATE ION, MANGANESE (II) ION, ...
著者Durbecq, V., Sainz, G., Oudjama, Y., Clantin, B., Bompard-Gilles, C., Tricot, C., Caillet, J., Stalon, V., Droogmans, L., Villeret, V.
登録日2001-01-11
公開日2001-07-11
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomerase.
Embo J., 20, 2001
1HZT
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CRYSTAL STRUCTURE OF METAL-FREE ISOPENTENYL DIPHOSPHATE:DIMETHYLALLYL DIPHOSPHATE ISOMERASE
分子名称:ISOPENTENYL DIPHOSPHATE DELTA-ISOMERASE
著者Durbecq, V., Sainz, G., Oudjama, Y., Clantin, B., Bompard-Gilles, C., Tricot, C., Caillet, J., Stalon, V., Droogmans, L., Villeret, V.
登録日2001-01-26
公開日2001-07-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomerase.
Embo J., 20, 2001
3SDG
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ETHIONAMIDE BOOSTERS PART 2: COMBINING BIOISOSTERIC REPLACEMENT AND STRUCTURE-BASED DRUG DESIGN TO SOLVE PHARMACOKINETIC ISSUES IN A SERIES OF POTENT 1,2,4-OXADIAZOLE ETHR INHIBITORS.
分子名称:HTH-type transcriptional regulator EthR, 4,4,4-trifluoro-1-{4-[3-(1,3-thiazol-2-yl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}butan-1-one
著者Flipo, M., Desroses, M., Lecat-Guillet, N., Villemagne, B., Blondiaux, N., Leroux, F., Piveteau, C., Mathys, V., Flament, M.P., Siepmann, J., Villeret, V., Wohlkonig, A., Wintjens, R., Soror, S.H., Christophe, T., Jeon, H.K., Locht, C., Brodin, P., D prez, B., Baulard, A.R., Willand, N.
登録日2011-06-09
公開日2011-12-07
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors.
J.Med.Chem., 55, 2012
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