Author results

1FPI
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FRUCTOSE-1,6-BISPHOSPHATASE (D-FRUCTOSE-1,6-BISPHOSPHATE 1-PHOSPHOHYDROLASE) COMPLEXED WITH AMP, 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE AND POTASSIUM IONS (100 MM)
Descriptor:FRUCTOSE-1,6-BISPHOSPHATASE, POTASSIUM ION, ADENOSINE MONOPHOSPHATE, ...
Authors:Villeret, V., Lipscomb, W.N.
Deposit date:1995-06-02
Release date:1996-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase.
Proc.Natl.Acad.Sci.USA, 92, 1995
1FPJ
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FRUCTOSE-1,6-BISPHOSPHATASE (D-FRUCTOSE-1,6-BISPHOSPHATE 1-PHOSPHOHYDROLASE) COMPLEXED WITH AMP, 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE, THALLIUM (10 MM) AND LITHIUM IONS (10 MM)
Descriptor:FRUCTOSE-1,6-BISPHOSPHATASE, THALLIUM (I) ION, ADENOSINE MONOPHOSPHATE, ...
Authors:Villeret, V., Lipscomb, W.N.
Deposit date:1995-06-02
Release date:1996-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase.
Proc.Natl.Acad.Sci.USA, 92, 1995
1FPK
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FRUCTOSE-1,6-BISPHOSPHATASE (D-FRUCTOSE-1,6-BISPHOSPHATE 1-PHOSPHOHYDROLASE) COMPLEXED WITH THALLIUM IONS (10 MM)
Descriptor:FRUCTOSE-1,6-BISPHOSPHATASE, THALLIUM (I) ION
Authors:Villeret, V., Lipscomb, W.N.
Deposit date:1995-06-02
Release date:1996-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase.
Proc.Natl.Acad.Sci.USA, 92, 1995
1FPL
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FRUCTOSE-1,6-BISPHOSPHATASE (D-FRUCTOSE-1,6-BISPHOSPHATE 1-PHOSPHOHYDROLASE) COMPLEXED WITH AMP, 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE AND THALLIUM IONS (10 MM)
Descriptor:FRUCTOSE-1,6-BISPHOSPHATASE, THALLIUM (I) ION, ADENOSINE MONOPHOSPHATE, ...
Authors:Villeret, V., Lipscomb, W.N.
Deposit date:1995-06-02
Release date:1996-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase.
Proc.Natl.Acad.Sci.USA, 92, 1995
1A1S
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ORNITHINE CARBAMOYLTRANSFERASE FROM PYROCOCCUS FURIOSUS
Descriptor:ORNITHINE CARBAMOYLTRANSFERASE
Authors:Villeret, V., Clantin, B., Tricot, C., Legrain, C., Roovers, M., Stalon, V., Glansdorff, N., Van Beeumen, J.
Deposit date:1997-12-15
Release date:1998-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of Pyrococcus furiosus ornithine carbamoyltransferase reveals a key role for oligomerization in enzyme stability at extremely high temperatures.
Proc.Natl.Acad.Sci.USA, 95, 1998
1ORT
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ORNITHINE TRANSCARBAMOYLASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:ORNITHINE TRANSCARBAMOYLASE
Authors:Villeret, V., Dideberg, O.
Deposit date:1995-08-24
Release date:1996-12-07
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of Pseudomonas aeruginosa catabolic ornithine transcarbamoylase at 3.0-A resolution: a different oligomeric organization in the transcarbamoylase family.
Proc.Natl.Acad.Sci.USA, 92, 1995
1FPD
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STRUCTURAL ASPECTS OF THE ALLOSTERIC INHIBITION OF FRUCTOSE-1,6-BISPHOSPHATASE BY AMP: THE BINDING OF BOTH THE SUBSTRATE ANALOGUE 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE AND CATALYTIC METAL IONS MONITORED BY X-RAY CRYSTALLOGRAPHY
Descriptor:FRUCTOSE 1,6-BISPHOSPHATASE, MANGANESE (II) ION, 2,5-ANHYDROGLUCITOL-1,6-BIPHOSPHATE, ...
Authors:Villeret, V., Huang, S., Zhang, Y., Lipscomb, W.N.
Deposit date:1994-12-15
Release date:1995-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural aspects of the allosteric inhibition of fructose-1,6-bisphosphatase by AMP: the binding of both the substrate analogue 2,5-anhydro-D-glucitol 1,6-bisphosphate and catalytic metal ions monitored by X-ray crystallography.
Biochemistry, 34, 1995
1FPE
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STRUCTURAL ASPECTS OF THE ALLOSTERIC INHIBITION OF FRUCTOSE-1,6-BISPHOSPHATASE BY AMP: THE BINDING OF BOTH THE SUBSTRATE ANALOGUE 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE AND CATALYTIC METAL IONS MONITORED BY X-RAY CRYSTALLOGRAPHY
Descriptor:FRUCTOSE 1,6-BISPHOSPHATASE, MANGANESE (II) ION, 2,5-ANHYDROGLUCITOL-1,6-BIPHOSPHATE, ...
Authors:Villeret, V., Huang, S., Zhang, Y., Lipscomb, W.N.
Deposit date:1994-12-15
Release date:1995-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural aspects of the allosteric inhibition of fructose-1,6-bisphosphatase by AMP: the binding of both the substrate analogue 2,5-anhydro-D-glucitol 1,6-bisphosphate and catalytic metal ions monitored by X-ray crystallography.
Biochemistry, 34, 1995
1FPF
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STRUCTURAL ASPECTS OF THE ALLOSTERIC INHIBITION OF FRUCTOSE-1,6-BISPHOSPHATASE BY AMP: THE BINDING OF BOTH THE SUBSTRATE ANALOGUE 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE AND CATALYTIC METAL IONS MONITORED BY X-RAY CRYSTALLOGRAPHY
Descriptor:FRUCTOSE 1,6-BISPHOSPHATASE, MANGANESE (II) ION, 2,5-ANHYDROGLUCITOL-1,6-BIPHOSPHATE, ...
Authors:Villeret, V., Huang, S., Zhang, Y., Lipscomb, W.N.
Deposit date:1994-12-15
Release date:1995-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural aspects of the allosteric inhibition of fructose-1,6-bisphosphatase by AMP: the binding of both the substrate analogue 2,5-anhydro-D-glucitol 1,6-bisphosphate and catalytic metal ions monitored by X-ray crystallography.
Biochemistry, 34, 1995
1FPG
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STRUCTURAL ASPECTS OF THE ALLOSTERIC INHIBITION OF FRUCTOSE-1,6-BISPHOSPHATASE BY AMP: THE BINDING OF BOTH THE SUBSTRATE ANALOGUE 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE AND CATALYTIC METAL IONS MONITORED BY X-RAY CRYSTALLOGRAPHY
Descriptor:FRUCTOSE 1,6-BISPHOSPHATASE, MANGANESE (II) ION, 2,5-ANHYDROGLUCITOL-1,6-BIPHOSPHATE, ...
Authors:Villeret, V., Huang, S., Zhang, Y., Lipscomb, W.N.
Deposit date:1994-12-15
Release date:1995-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural aspects of the allosteric inhibition of fructose-1,6-bisphosphatase by AMP: the binding of both the substrate analogue 2,5-anhydro-D-glucitol 1,6-bisphosphate and catalytic metal ions monitored by X-ray crystallography.
Biochemistry, 34, 1995
1SPI
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CRYSTAL STRUCTURE OF SPINACH CHLOROPLAST FRUCTOSE-1,6-BISPHOSPHATASE AT 2.8 ANGSTROMS RESOLUTION
Descriptor:FRUCTOSE 1,6-BISPHOSPHATASE
Authors:Villeret, V., Huang, S., Zhang, Y., Xue, Y., Lipscomb, W.N.
Deposit date:1994-12-14
Release date:1995-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of spinach chloroplast fructose-1,6-bisphosphatase at 2.8 A resolution.
Biochemistry, 34, 1995
1H71
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PSYCHROPHILIC PROTEASE FROM PSEUDOALTEROMONAS 'TAC II 18'
Descriptor:SERRALYSIN, CALCIUM ION, ZINC ION
Authors:Villeret, V., Van Petegem, F., Aghajari, N., Chessa, J.-P., Gerday, C., Haser, R., Van Beeumen, J.
Deposit date:2001-07-02
Release date:2003-02-13
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of a Psychrophilic Metalloprotease Reveal New Insights Into Catalysis by Cold-Adapted Proteases
Proteins: Struct.,Funct., Genet., 50, 2003
3G1L
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ETHR FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH COMPOUND BDM14744
Descriptor:TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR, 3-(4-fluorophenyl)-5-phenyl-4H-1,2,4-triazole
Authors:Willand, N., Dirie, B., Carette, X., Bifani, P., Singhal, A., Desroses, M., Leroux, F., Willery, E., Mathys, V., Deprez-Poulain, R., Delcroix, G., Frenois, F., Aumercier, M., Locht, C., Villeret, V., Deprez, B., Baulard, A.R.
Deposit date:2009-01-30
Release date:2009-07-21
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Synthetic EthR inhibitors boost antituberculous activity of ethionamide.
Nat.Med. (N.Y.), 15, 2009
3G1M
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ETHR FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH COMPOUND BDM31381
Descriptor:TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR, 1-(thiophen-2-ylacetyl)-4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)piperidine
Authors:Willand, N., Dirie, B., Carette, X., Bifani, P., Singhal, A., Desroses, M., Leroux, F., Willery, E., Mathys, V., Deprez-Poulain, R., Delcroix, G., Frenois, F., Aumercier, M., Locht, C., Villeret, V., Deprez, B., Baulard, A.R.
Deposit date:2009-01-30
Release date:2009-07-21
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Synthetic EthR inhibitors boost antituberculous activity of ethionamide.
Nat.Med. (N.Y.), 15, 2009
3G1O
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ETHR FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH COMPOUND BDM14500
Descriptor:TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR, tert-butyl 4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)piperidine-1-carboxylate
Authors:Willand, N., Dirie, B., Carette, X., Bifani, P., Singhal, A., Desroses, M., Leroux, F., Willery, E., Mathys, V., Deprez-Poulain, R., Delcroix, G., Frenois, F., Aumercier, M., Locht, C., Villeret, V., Deprez, B., Baulard, A.R.
Deposit date:2009-01-30
Release date:2009-07-21
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Synthetic EthR inhibitors boost antituberculous activity of ethionamide.
NAT.MED. (N.Y.), 15, 2009
3QPL
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G106W MUTANT OF ETHR FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:HTH-type transcriptional regulator EthR
Authors:Carette, X., Willery, E., Hoos, S., Lecat-Guillet, N., Frenois, F., Dirie, B., Villeret, V., England, P., Deprez, B., Locht, C., Willand, N., Baulard, A.
Deposit date:2011-02-14
Release date:2011-12-28
Last modified:2012-05-09
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands.
Nucleic Acids Res., 40, 2012
1B65
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STRUCTURE OF L-AMINOPEPTIDASE D-ALA-ESTERASE/AMIDASE FROM OCHROBACTRUM ANTHROPI, A PROTOTYPE FOR THE SERINE AMINOPEPTIDASES, REVEALS A NEW VARIANT AMONG THE NTN HYDROLASE FOLD
Descriptor:PROTEIN (AMINOPEPTIDASE)
Authors:Bompard-Gilles, C., Villeret, V., Davies, G.J., Fanuel, L., Joris, B., Frere, J.M., Van Beeumen, J.
Deposit date:1999-01-20
Release date:1999-07-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:A new variant of the Ntn hydrolase fold revealed by the crystal structure of L-aminopeptidase D-ala-esterase/amidase from Ochrobactrum anthropi.
Structure Fold.Des., 8, 2000
4QL0
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CRYSTAL STRUCTURE ANALYSIS OF THE MEMBRANE TRANSPORTER FHAC (DOUBLE MUTANT V169T, I176N)
Descriptor:Filamentous hemagglutinin transporter protein FhaC, TRIETHYLENE GLYCOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Maier, T., Clantin, B., Gruss, F., Dewitte, F., Delattre, A.S., Jacob-Dubuisson, F., Hiller, S., Villeret, V.
Deposit date:2014-06-10
Release date:2015-06-17
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Conserved Omp85 lid-lock structure and substrate recognition in FhaC
Nat Commun, 6, 2015
3CQL
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CRYSTAL STRUCTURE OF GH FAMILY 19 CHITINASE FROM CARICA PAPAYA
Descriptor:Endochitinase, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Huet, J., Rucktoa, P., Clantin, B., Azarkan, M., Looze, Y., Villeret, V., Wintjens, R.
Deposit date:2008-04-03
Release date:2008-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:X-ray Structure of Papaya Chitinase Reveals the Substrate Binding Mode of Glycosyl Hydrolase Family 19 Chitinases.
Biochemistry, 47, 2008
2FAW
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CRYSTAL STRUCTURE OF PAPAYA GLUTAMINYL CYCLASE
Descriptor:glutamine cyclotransferase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Wintjens, R., Belrhali, H., Clantin, B., Azarkan, M., Bompard, C., Baeyens-Volant, D., Looze, Y., Villeret, V.
Deposit date:2005-12-08
Release date:2006-10-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of papaya glutaminyl cyclase, an archetype for plant and bacterial glutaminyl cyclases.
J.Mol.Biol., 357, 2006
4QKY
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CRYSTAL STRUCTURE ANALYSIS OF THE MEMBRANE TRANSPORTER FHAC
Descriptor:Filamentous hemagglutinin transporter protein FhaC, PHOSPHATE ION
Authors:Maier, T., Clantin, B., Gruss, F., Dewitte, F., Delattre, A.S., Jacob-Dubuisson, F., Hiller, S., Villeret, V.
Deposit date:2014-06-10
Release date:2014-10-22
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Conserved Omp85 lid-lock structure and substrate recognition in FhaC
Nat Commun, 6, 2015
5ODD
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HUMAN MED26 N-TERMINAL DOMAIN (1-92)
Descriptor:Mediator of RNA polymerase II transcription subunit 26
Authors:Lens, Z., Cantrelle, F.-X., Perruzini, R., Dewitte, F., Hanoulle, X., Villeret, V., Verger, A., Landrieu, I.
Deposit date:2017-07-05
Release date:2017-11-29
Last modified:2020-01-29
Method:SOLUTION NMR
Cite:1H, 15N and 13C assignments of the N-terminal domain of the Mediator complex subunit MED26.
Biomol.Nmr Assign., 10, 2016
1HX3
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CRYSTAL STRUCTURE OF E.COLI ISOPENTENYL DIPHOSPHATE:DIMETHYLALLYL DIPHOSPHATE ISOMERASE
Descriptor:ISOPENTENYL DIPHOSPHATE DELTA-ISOMERASE, SULFATE ION, MANGANESE (II) ION, ...
Authors:Durbecq, V., Sainz, G., Oudjama, Y., Clantin, B., Bompard-Gilles, C., Tricot, C., Caillet, J., Stalon, V., Droogmans, L., Villeret, V.
Deposit date:2001-01-11
Release date:2001-07-11
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomerase.
Embo J., 20, 2001
1HZT
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CRYSTAL STRUCTURE OF METAL-FREE ISOPENTENYL DIPHOSPHATE:DIMETHYLALLYL DIPHOSPHATE ISOMERASE
Descriptor:ISOPENTENYL DIPHOSPHATE DELTA-ISOMERASE
Authors:Durbecq, V., Sainz, G., Oudjama, Y., Clantin, B., Bompard-Gilles, C., Tricot, C., Caillet, J., Stalon, V., Droogmans, L., Villeret, V.
Deposit date:2001-01-26
Release date:2001-07-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomerase.
Embo J., 20, 2001
3SDG
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ETHIONAMIDE BOOSTERS PART 2: COMBINING BIOISOSTERIC REPLACEMENT AND STRUCTURE-BASED DRUG DESIGN TO SOLVE PHARMACOKINETIC ISSUES IN A SERIES OF POTENT 1,2,4-OXADIAZOLE ETHR INHIBITORS.
Descriptor:HTH-type transcriptional regulator EthR, 4,4,4-trifluoro-1-{4-[3-(1,3-thiazol-2-yl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}butan-1-one
Authors:Flipo, M., Desroses, M., Lecat-Guillet, N., Villemagne, B., Blondiaux, N., Leroux, F., Piveteau, C., Mathys, V., Flament, M.P., Siepmann, J., Villeret, V., Wohlkonig, A., Wintjens, R., Soror, S.H., Christophe, T., Jeon, H.K., Locht, C., Brodin, P., D prez, B., Baulard, A.R., Willand, N.
Deposit date:2011-06-09
Release date:2011-12-07
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors.
J.Med.Chem., 55, 2012
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