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1NDL
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THE AWD NUCLEOTIDE DIPHOSPHATE KINASE FROM DROSOPHILA
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE
Authors:Janin, J., Chiadmi, M., Dumas, C., Lascu, I., Lebras, G., Morera, S., Veron, M.
Deposit date:1993-11-27
Release date:1994-04-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the Awd nucleotide diphosphate kinase from Drosophila.
Structure, 1, 1993
1NDP
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ADENOSINE 5'-DIPHOSPHATE BINDING AND THE ACTIVE SITE OF NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Janin, J., Morera, S., Dumas, C., Lascu, I., Lebras, G., Veron, M.
Deposit date:1993-11-29
Release date:1994-04-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Adenosine 5'-diphosphate binding and the active site of nucleoside diphosphate kinase.
Biochemistry, 33, 1994
1BUX
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3'-PHOSPHORYLATED NUCLEOTIDES BINDING TO NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE, 3'-PHOSPHATE-ADENOSINE-5'-PHOSPHATE SULFATE
Authors:Xu, Y., Schneider, B., Deville-Bonne, D., Veron, M., Janin, J.
Deposit date:1998-09-07
Release date:1999-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:3'-Phosphorylated nucleotides are tight binding inhibitors of nucleoside diphosphate kinase activity.
J.Biol.Chem., 273, 1998
2V4H
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NEMO CC2-LZ DOMAIN - 1D5 DARPIN COMPLEX
Descriptor:NF-KAPPA-B ESSENTIAL MODULATOR, 1D5 DARPIN
Authors:Grubisha, O., Duquerroy, S., Cordier, F., Haouz, A., Delepierre, M., Veron, M., Agou, F.
Deposit date:2008-09-22
Release date:2009-11-03
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Darpin-Assisted Crystallography of the Cc2-Lz Domain of Nemo Reveals a Coupling between Dimerization and Ubiquitin-Binding.
J.Mol.Biol., 395, 2010
1HHQ
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ROLE OF ACTIVE SITE RESIUDE LYS16 IN NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE, SULFATE ION
Authors:Schneider, B., Babolat, M., Xu, Y.W., Janin, J., Veron, M., Deville-Bonne, D.
Deposit date:2000-12-26
Release date:2001-05-31
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanism of Phosphoryl Transfer by Nucleoside Diphosphate Kinase Ph-Dependence and Role of Active Site Lys16 and Tyr56 Residues
Eur.J.Biochem., 268, 2001
1MN9
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NDP KINASE MUTANT (H122G) COMPLEX WITH RTP
Descriptor:NDP kinase, MAGNESIUM ION, RIBAVIRIN TRIPHOSPHATE
Authors:Gallois-montbrun, S., Chen, Y., Dutartre, H., Morera, S., Guerreiro, C., Mulard, L., Schneider, B., Janin, J., Canard, B., Veron, M., Deville-bonne, D.
Deposit date:2002-09-05
Release date:2003-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Analysis of the Activation of Ribavirin Analogs by NDP Kinase: Comparison with Other Ribavirin Targets
MOL.PHARMACOL., 63, 2003
2JVX
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SOLUTION STRUCTURE OF HUMAN NEMO ZINC FINGER
Descriptor:NF-kappa-B essential modulator, ZINC ION
Authors:Cordier, F., Vinolo, E., Veron, M., Delepierre, M., Agou, F.
Deposit date:2007-09-28
Release date:2008-03-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of NEMO zinc finger and impact of an anhidrotic ectodermal dysplasia with immunodeficiency-related point mutation.
J.Mol.Biol., 377, 2008
2JVY
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SOLUTION STRUCTURE OF THE EDA-ID-RELATED C417F MUTANT OF HUMAN NEMO ZINC FINGER
Descriptor:NF-kappa-B essential modulator, ZINC ION
Authors:Cordier, F., Vinolo, E., Veron, M., Delepierre, M., Agou, F.
Deposit date:2007-09-28
Release date:2008-03-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of NEMO zinc finger and impact of an anhidrotic ectodermal dysplasia with immunodeficiency-related point mutation.
J.Mol.Biol., 377, 2008
1F3F
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STRUCTURE OF THE H122G NUCLEOSIDE DIPHOSPHATE KINASE / D4T-TRIPHOSPHATE.MG COMPLEX
Descriptor:PROTEIN (NUCLEOSIDE DIPHOSPHATE KINASE), MAGNESIUM ION, 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE, ...
Authors:Meyer, P., Schneider, B., Sarfati, S., Deville-Bonne, D., Guerreiro, C., Boretto, J., Janin, J., Veron, M., Canard, B.
Deposit date:2000-06-02
Release date:2000-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis for activation of alpha-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase.
EMBO J., 19, 2000
1F6T
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STRUCTURE OF THE NUCLEOSIDE DIPHOSPHATE KINASE/ALPHA-BORANO(RP)-TDP.MG COMPLEX
Descriptor:PROTEIN (NUCLEOSIDE DIPHOSPHATE KINASE), MAGNESIUM ION, 2*-DEOXY-THYMIDINE-5*-ALPHA BORANO DIPHOSPHATE (ISOMER RP)
Authors:Guerreiro, C., Boretto, J., Janin, J., Veron, M., Canard, B., Schneider, B., Sarfati, S., Deville-Bonne, D.
Deposit date:2000-06-23
Release date:2000-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis for activation of alpha-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase.
EMBO J., 19, 2000
1LEO
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P100S NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE
Authors:Janin, J., Xu, Y., Veron, M.
Deposit date:1996-05-22
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Nucleoside diphosphate kinase. Investigation of the intersubunit contacts by site-directed mutagenesis and crystallography.
J.Biol.Chem., 271, 1996
1MN7
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NDP KINASE MUTANT (H122G;N119S;F64W) IN COMPLEX WITH ABAZTTP
Descriptor:NDP kinase, MAGNESIUM ION, 3'-AZIDO-3'-DEOXY-THYMIDINE-5'-ALPHA BORANO TRIPHOSPHATE
Authors:gallois-montbrun, s., schneider, b., chen, y., giacomoni-fernandes, v., mulard, l., morera, s., janin, j., deville-bonne, d., veron, m.
Deposit date:2002-09-05
Release date:2002-10-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Improving nucleoside diphosphate kinase for antiviral nucleotide analogs activation
J.BIOL.CHEM., 277, 2002
1NDK
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X-RAY STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE
Authors:Janin, J., Dumas, C., Morera, S., Lascu, I., Veron, M.
Deposit date:1993-07-15
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray structure of nucleoside diphosphate kinase.
EMBO J., 11, 1992
1NPK
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REFINED X-RAY STRUCTURE OF DICTYOSTELIUM NUCLEOSIDE DIPHOSPHATE KINASE AT 1,8 ANGSTROMS RESOLUTION
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE
Authors:Janin, J., Morera, S., Lebras, G., Lascu, I., Veron, M.
Deposit date:1994-07-27
Release date:1994-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Refined X-ray structure of Dictyostelium discoideum nucleoside diphosphate kinase at 1.8 A resolution.
J.Mol.Biol., 243, 1994
1S5Z
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NDP KINASE IN COMPLEX WITH ADENOSINE PHOSPHONOACETIC ACID
Descriptor:Nucleoside diphosphate kinase, cytosolic, ADENOSINE PHOSPHONOACETIC ACID, ...
Authors:Chen, Y., Morera, S., Pasti, C., Angusti, A., Solaroli, N., Veron, M., Janin, J., Manfredini, S., Deville-Bonne, D.
Deposit date:2004-01-22
Release date:2005-02-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Adenosine phosphonoacetic acid is slowly metabolized by NDP kinase.
Med.Chem., 1, 2005
1UCN
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X-RAY STRUCTURE OF HUMAN NUCLEOSIDE DIPHOSPHATE KINASE A COMPLEXED WITH ADP AT 2 A RESOLUTION
Descriptor:nucleoside diphosphate kinase A, PHOSPHATE ION, CALCIUM ION, ...
Authors:Chen, Y., Gallois-Montbrun, S., Schneider, B., Veron, M., Morera, S., Deville-Bonne, D., Janin, J.
Deposit date:2003-04-16
Release date:2003-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Nucleotide Binding to Nucleoside Diphosphate Kinases: X-ray Structure of Human NDPK-A in Complex with ADP and Comparison to Protein Kinases
J.Mol.Biol., 332, 2003
1NDC
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X-RAY STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE COMPLEXED WITH DTDP AND MG2+ AT 2 A RESOLUTION
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE, MAGNESIUM ION, THYMIDINE-5'-DIPHOSPHATE
Authors:Cherfils, J., Morera, S., Janin, J.
Deposit date:1994-04-27
Release date:1994-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of nucleoside diphosphate kinase complexed with thymidine diphosphate and Mg2+ at 2-A resolution.
Biochemistry, 33, 1994
1B4S
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STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE H122G MUTANT
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE, PHOSPHATE ION, MAGNESIUM ION, ...
Authors:Meyer, P., Janin, J.
Deposit date:1998-12-28
Release date:1999-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Nucleophilic activation by positioning in phosphoryl transfer catalyzed by nucleoside diphosphate kinase.
Biochemistry, 38, 1999
1LWX
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AZT DIPHOSPHATE BINDING TO NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE, MAGNESIUM ION, 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-DIPHOSPHATE
Authors:Janin, J., Xu, Y.
Deposit date:1997-04-30
Release date:1997-08-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray analysis of azido-thymidine diphosphate binding to nucleoside diphosphate kinase.
Proc.Natl.Acad.Sci.USA, 94, 1997
1NCL
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THERMAL STABILITY OF HEXAMERIC AND TETRAMERIC NUCLEOSIDE, DIPHOSPHATE KINASES
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE
Authors:Janin, J., Morera, S., Lascu, I.
Deposit date:1996-03-22
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Thermal stability of hexameric and tetrameric nucleoside diphosphate kinases. Effect of subunit interaction.
J.Biol.Chem., 271, 1996
1NSP
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MECHANISM OF PHOSPHATE TRANSFER BY NUCLEOSIDE DIPHOSPHATE KINASE: X-RAY STRUCTURES OF A PHOSPHO-HISTIDINE INTERMEDIATE OF THE ENZYMES FROM DROSOPHILA AND DICTYOSTELIUM
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE
Authors:Janin, J., Morera, S., Chiadmi, M., Lebras, G., Lascu, I.
Deposit date:1995-04-18
Release date:1995-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanism of phosphate transfer by nucleoside diphosphate kinase: X-ray structures of the phosphohistidine intermediate of the enzymes from Drosophila and Dictyostelium.
Biochemistry, 34, 1995
1NSQ
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MECHANISM OF PHOSPHATE TRANSFER BY NUCLEOSIDE DIPHOSPHATE KINASE: X-RAY STRUCTURES OF A PHOSPHO-HISTIDINE INTERMEDIATE OF THE ENZYMES FROM DROSOPHILA AND DICTYOSTELIUM
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE
Authors:Janin, J., Chiadmi, M., Morera, S., Lebras, G., Lascu, I.
Deposit date:1995-04-24
Release date:1995-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Mechanism of phosphate transfer by nucleoside diphosphate kinase: X-ray structures of the phosphohistidine intermediate of the enzymes from Drosophila and Dictyostelium.
Biochemistry, 34, 1995
1B99
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3'-FLUORO-URIDINE DIPHOSPHATE BINDING TO NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor:PROTEIN (NUCLEOSIDE DIPHOSPHATE KINASE), 2',3'-DIDEOXY-3'-FLUORO-URIDIDINE-5'-DIPHOSPHATE, PYROPHOSPHATE 2-
Authors:Janin, J., Xu, Y.
Deposit date:1999-02-22
Release date:1999-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Catalytic mechanism of nucleoside diphosphate kinase investigated using nucleotide analogues, viscosity effects, and X-ray crystallography.
Biochemistry, 38, 1999
4BWN
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NEMO CC2-LZ DOMAIN
Descriptor:NF-KAPPA-B ESSENTIAL MODULATOR
Authors:Dubosclard, V., Duquerroy, S., Fontan, E., Agou, F.
Deposit date:2013-07-03
Release date:2014-07-23
Last modified:2014-10-29
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:High-Resolution of Crystal Structure of the Human Cc2-Lz Domain of Nemo by Protein Engineering
To be Published
1KDN
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STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE, MAGNESIUM ION, ALUMINUM FLUORIDE, ...
Authors:Cherfils, J., Xu, Y.W., Morera, S., Janin, J.
Deposit date:1996-09-10
Release date:1997-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:AlF3 mimics the transition state of protein phosphorylation in the crystal structure of nucleoside diphosphate kinase and MgADP.
Proc.Natl.Acad.Sci.USA, 94, 1997