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1ZLH
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CRYSTAL STRUCTURE OF THE TICK CARBOXYPEPTIDASE INHIBITOR IN COMPLEX WITH BOVINE CARBOXYPEPTIDASE A
Descriptor:Carboxypeptidase A1, carboxypeptidase inhibitor, ZINC ION
Authors:Arolas, J.L., Popowicz, G.M., Lorenzo, J., Sommerhoff, C.P., Huber, R., Aviles, F.X., Holak, T.A.
Deposit date:2005-05-06
Release date:2005-07-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode
J.Mol.Biol., 350, 2005
1ZLI
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CRYSTAL STRUCTURE OF THE TICK CARBOXYPEPTIDASE INHIBITOR IN COMPLEX WITH HUMAN CARBOXYPEPTIDASE B
Descriptor:Carboxypeptidase B, carboxypeptidase inhibitor, ZINC ION
Authors:Arolas, J.L., Popowicz, G.M., Lorenzo, J., Sommerhoff, C.P., Huber, R., Aviles, F.X., Holak, T.A.
Deposit date:2005-05-06
Release date:2005-07-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode
J.Mol.Biol., 350, 2005
1A0L
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HUMAN BETA-TRYPTASE: A RING-LIKE TETRAMER WITH ACTIVE SITES FACING A CENTRAL PORE
Descriptor:BETA-TRYPTASE, (2S)-3-(4-carbamimidoylphenyl)-2-hydroxypropanoic acid
Authors:Pereira, P.J.B., Bergner, A., Macedo-Ribeiro, S., Huber, R., Matschiner, G., Fritz, H., Sommerhoff, C.P., Bode, W.
Deposit date:1997-12-03
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.
Nature, 392, 1998
1LTO
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HUMAN ALPHA1-TRYPTASE
Descriptor:alpha tryptase I
Authors:Marquardt, U., Zettl, F., Huber, R., Bode, W., Sommerhoff, C.P.
Deposit date:2002-05-20
Release date:2003-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structure of Human alpha1-Tryptase Reveals a Blocked Substrate-binding Region
J.MOL.BIOL., 321, 2002
1LDT
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COMPLEX OF LEECH-DERIVED TRYPTASE INHIBITOR WITH PORCINE TRYPSIN
Descriptor:TRYPSIN, TRYPTASE INHIBITOR, CALCIUM ION
Authors:Stubbs, M.T.
Deposit date:1997-05-15
Release date:1998-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The three-dimensional structure of recombinant leech-derived tryptase inhibitor in complex with trypsin. Implications for the structure of human mast cell tryptase and its inhibition.
J.Biol.Chem., 272, 1997
2LFK
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NMR SOLUTION STRUCTURE OF NATIVE TDPI-SHORT
Descriptor:Tryptase inhibitor
Authors:Bronsoms, S., Pantoja-Uceda, D., Gabrijelcic-Geiger, D., Sanglas, L., Aviles, F., Santoro, J., Sommerhoff, C., Arolas, J.
Deposit date:2011-07-06
Release date:2011-11-09
Last modified:2011-12-28
Method:SOLUTION NMR
Cite:Oxidative folding and structural analyses of a kunitz-related inhibitor and its disulfide intermediates: functional implications.
J.Mol.Biol., 414, 2011
2LFL
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NMR SOLUTION STRUCTURE OF THE INTERMEDIATE IIIB OF TDPI-SHORT
Descriptor:Tryptase inhibitor
Authors:Bronsoms, S., Pantoja-Uceda, D., Gabrijelcic-Geiger, D., Sanglas, L., Aviles, F., Santoro, J., Sommerhoff, C., Arolas, J.
Deposit date:2011-07-06
Release date:2011-11-09
Last modified:2011-12-28
Method:SOLUTION NMR
Cite:Oxidative folding and structural analyses of a kunitz-related inhibitor and its disulfide intermediates: functional implications.
J.Mol.Biol., 414, 2011
1AN1
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LEECH-DERIVED TRYPTASE INHIBITOR/TRYPSIN COMPLEX
Descriptor:TRYPSIN, TRYPTASE INHIBITOR, CALCIUM ION
Authors:Priestle, J.P., Di Marco, S.
Deposit date:1997-06-26
Release date:1998-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.
Structure, 5, 1997
2KMO
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SOLUTION STRUCTURE OF NATIVE LEECH-DERIVED TRYPTASE INHIBITOR, LDTI
Descriptor:Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D., Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMP
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SOLUTION STRUCTURE OF INTERMEIDATE IIA OF LEECK-DERIVED TRYPTASE INHIBITOR, LDTI.
Descriptor:Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D., Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMQ
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SOLUTION STRUCTURE OF INTERMEDIATE IIB OF LEECH-DERIVED TRYPTASE INHIBITOR, LDTI.
Descriptor:Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D., Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMR
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SOLUTION STRUCTURE OF INTERMEDIATE IIC OF LEECH-DERIVED TRYPTASE INHIBITOR, LDTI.
Descriptor:Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D., Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
1BX7
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HIRUSTASIN FROM HIRUDO MEDICINALIS AT 1.2 ANGSTROMS
Descriptor:HIRUSTASIN, SULFATE ION
Authors:Uson, I., Sheldrick, G.M., De La Fortelle, E., Bricogne, G., Di Marco, S., Priestle, J.P., Gruetter, M.G., Mittl, P.R.E.
Deposit date:1998-10-14
Release date:1999-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The 1.2 A crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors.
Structure Fold.Des., 7, 1999
1BX8
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HIRUSTASIN FROM HIRUDO MEDICINALIS AT 1.4 ANGSTROMS
Descriptor:HIRUSTASIN, SULFATE ION
Authors:Uson, I., Sheldrick, G.M., De La Fortelle, E., Bricogne, G., Di Marco, S., Priestle, J.P., Gruetter, M.G., Mittl, P.R.E.
Deposit date:1998-10-14
Release date:1999-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The 1.2 A crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors.
Structure Fold.Des., 7, 1999
1TFX
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COMPLEX OF THE SECOND KUNITZ DOMAIN OF TISSUE FACTOR PATHWAY INHIBITOR WITH PORCINE TRYPSIN
Descriptor:TRYPSIN, TISSUE FACTOR PATHWAY INHIBITOR, CALCIUM ION
Authors:Stubbs, M.T., Huber, R.
Deposit date:1997-01-21
Release date:1998-01-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa.
J.Mol.Biol., 269, 1997
2IT8
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SOLUTION STRUCTURE OF A LINEAR ANALOG OF THE CYCLIC SQUASH TRYPSIN INHIBITOR MCOTI-II
Descriptor:Trypsin inhibitor 2
Authors:Avrutina, O., Chiche, L., Diederichsen, U., Heitz, A., Kolmar, H.
Deposit date:2006-10-19
Release date:2007-10-02
Last modified:2014-04-02
Method:SOLUTION NMR
Cite:Knottin cyclization: Structure and stability of cyclic and linear squash inhibitors do not differ significantly
To be Published