1GUH
| Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the MU and PI class enzymes | Descriptor: | GLUTATHIONE S-TRANSFERASE A1-1, S-BENZYL-GLUTATHIONE | Authors: | Sinning, I, Kleywegt, G.J, Jones, T.A. | Deposit date: | 1993-02-24 | Release date: | 1993-10-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes. J.Mol.Biol., 232, 1993
|
|
1SUR
| PHOSPHO-ADENYLYL-SULFATE REDUCTASE | Descriptor: | PAPS REDUCTASE | Authors: | Sinning, I, Savage, H. | Deposit date: | 1998-04-01 | Release date: | 1999-05-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of phosphoadenylyl sulphate (PAPS) reductase: a new family of adenine nucleotide alpha hydrolases. Structure, 5, 1997
|
|
2EV4
| Structure of Rv1264N, the regulatory domain of the mycobacterial adenylyl cylcase Rv1264, with a salt precipitant | Descriptor: | CHLORIDE ION, Hypothetical protein Rv1264/MT1302, OLEIC ACID | Authors: | Findeisen, F, Tews, I, Sinning, I. | Deposit date: | 2005-10-30 | Release date: | 2006-11-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | The structure of the regulatory domain of the adenylyl cyclase Rv1264 from Mycobacterium tuberculosis with bound oleic acid J.Mol.Biol., 369, 2007
|
|
8ODU
| Chaetomium thermophilum Get1/Get2 heterotetramer in complex with a Get3 dimer (amphipol) | Descriptor: | ATPase GET3, Protein GET2,Protein GET1, ZINC ION | Authors: | McDowell, M.A, Wild, K, Sinning, I. | Deposit date: | 2023-03-09 | Release date: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | The GET insertase exhibits conformational plasticity and induces membrane thinning. Nat Commun, 14, 2023
|
|
8ODV
| Chaetomium thermophilum Get1/Get2 heterotetramer in complex with a Get3 dimer (nanodisc) | Descriptor: | ATPase GET3, Protein GET2,Protein GET1, ZINC ION | Authors: | McDowell, M.A, Wild, K, Sinning, I. | Deposit date: | 2023-03-09 | Release date: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | The GET insertase exhibits conformational plasticity and induces membrane thinning. Nat Commun, 14, 2023
|
|
6TH0
| Crystal structure of Arabidopsis thaliana NAA60 in complex with acetyl-CoA | Descriptor: | ACETYL COENZYME *A, Acyl-CoA N-acyltransferases (NAT) superfamily protein | Authors: | Layer, D, Kopp, J, Lapouge, K, Sinning, I. | Deposit date: | 2019-11-18 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The Arabidopsis N alpha -acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response. New Phytol., 228, 2020
|
|
3SYN
| Crystal structure of FlhF in complex with its activator | Descriptor: | ALUMINUM FLUORIDE, ATP-binding protein YlxH, Flagellar biosynthesis protein flhF, ... | Authors: | Bange, G, Kuemmerer, N, Wild, K, Sinning, I. | Deposit date: | 2011-07-18 | Release date: | 2011-11-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.063 Å) | Cite: | Structural basis for the molecular evolution of SRP-GTPase activation by protein. Nat.Struct.Mol.Biol., 18, 2011
|
|
5CK3
| Signal recognition particle receptor SRb-GTP/SRX complex from Chaetomium thermophilum | Descriptor: | GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Jadhav, B.R, Wild, K, Sinning, I. | Deposit date: | 2015-07-15 | Release date: | 2015-09-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure and Switch Cycle of SR beta as Ancestral Eukaryotic GTPase Associated with Secretory Membranes. Structure, 23, 2015
|
|
8CR1
| Homo sapiens Get1/Get2 heterotetramer in complex with a Get3 dimer | Descriptor: | ATPase ASNA1, Guided entry of tail-anchored proteins factor CAMLG,Guided entry of tail-anchored proteins factor 1,GET2-GET1, ZINC ION | Authors: | McDowell, M.A, Heimes, M, Wild, K, Sinning, I. | Deposit date: | 2023-03-07 | Release date: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The GET insertase exhibits conformational plasticity and induces membrane thinning. Nat Commun, 14, 2023
|
|
7OLD
| Thermophilic eukaryotic 80S ribosome at pe/E (TI)-POST state | Descriptor: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | Authors: | Kisonaite, M, Wild, K, Sinning, I. | Deposit date: | 2021-05-19 | Release date: | 2022-01-26 | Last modified: | 2022-02-09 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation. Nat Commun, 13, 2022
|
|
7OLC
| Thermophilic eukaryotic 80S ribosome at idle POST state | Descriptor: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | Authors: | Kisonaite, M, Wild, K, Sinning, I. | Deposit date: | 2021-05-19 | Release date: | 2022-01-26 | Last modified: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation. Nat Commun, 13, 2022
|
|
2PX3
| Crystal structure of FlhF complexed with GTP/Mg(2+) | Descriptor: | Flagellar biosynthesis protein flhF, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | Authors: | Bange, G, Wild, K, Sinning, I. | Deposit date: | 2007-05-14 | Release date: | 2007-09-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The crystal structure of the third signal-recognition particle GTPase FlhF reveals a homodimer with bound GTP. Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2PX0
| Crystal structure of FlhF complexed with GMPPNP/Mg(2+) | Descriptor: | Flagellar biosynthesis protein flhF, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Bange, G, Wild, K, Sinning, I. | Deposit date: | 2007-05-14 | Release date: | 2007-09-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The crystal structure of the third signal-recognition particle GTPase FlhF reveals a homodimer with bound GTP. Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
6Z00
| Arabidopsis thaliana Naa50 in complex with bisubstrate analogue CoA-Ac-MVNAL | Descriptor: | Acyl-CoA N-acyltransferases (NAT) superfamily protein, CARBOXYMETHYL COENZYME *A, MET-VAL-ASN-ALA-LEU | Authors: | Weidenhausen, J, Kopp, J, Lapouge, K, Sinning, I. | Deposit date: | 2020-05-07 | Release date: | 2020-12-30 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Structural and functional characterization of the N-terminal acetyltransferase Naa50. Structure, 29, 2021
|
|
6YZZ
| Arabidopsis thaliana Naa50 in complex with AcCoA | Descriptor: | ACETYL COENZYME *A, N-alpha-acetyltransferase 50 | Authors: | Weidenhausen, J, Kopp, J, Lapouge, K, Sinning, I. | Deposit date: | 2020-05-07 | Release date: | 2020-12-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structural and functional characterization of the N-terminal acetyltransferase Naa50. Structure, 29, 2021
|
|
8CR2
| Homo sapiens Get1/Get2 heterotetramer (a3' deletion variant) in complex with a Get3 dimer | Descriptor: | ATPase ASNA1, Guided entry of tail-anchored proteins factor CAMLG,Guided entry of tail-anchored proteins factor 1, ZINC ION | Authors: | McDowell, M.A, Heimes, M, Wild, K, Sinning, I. | Deposit date: | 2023-03-07 | Release date: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | The GET insertase exhibits conformational plasticity and induces membrane thinning. Nat Commun, 14, 2023
|
|
8CQZ
| Homo sapiens Get3 in complex with the Get1 cytoplasmic domain | Descriptor: | ATPase ASNA1, Guided entry of tail-anchored proteins factor 1 | Authors: | McDowell, M.A, Heimes, M, Wild, K, Saar, D, Sinning, I. | Deposit date: | 2023-03-07 | Release date: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The GET insertase exhibits conformational plasticity and induces membrane thinning. Nat Commun, 14, 2023
|
|
4V7F
| Arx1 pre-60S particle. | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Leidig, C, Thoms, M, Holdermann, I, Bradatsch, B, Berninghausen, O, Bange, G, Sinning, I, Hurt, E, Beckmann, R. | Deposit date: | 2013-12-10 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (8.7 Å) | Cite: | 60S ribosome biogenesis requires rotation of the 5S ribonucleoprotein particle. Nat Commun, 5, 2014
|
|
1MHN
| |
1Y10
| Mycobacterial adenylyl cyclase Rv1264, holoenzyme, inhibited state | Descriptor: | CALCIUM ION, Hypothetical protein Rv1264/MT1302, PENTAETHYLENE GLYCOL | Authors: | Tews, I, Findeisen, F, Sinning, I, Schultz, A, Schultz, J.E, Linder, J.U. | Deposit date: | 2004-11-16 | Release date: | 2005-05-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The structure of a pH-sensing mycobacterial adenylyl cyclase holoenzyme Science, 308, 2005
|
|
1Y11
| Mycobacterial adenylyl cyclase Rv1264, holoenzyme, active state | Descriptor: | GLYCEROL, Hypothetical protein Rv1264/MT1302, PENTAETHYLENE GLYCOL, ... | Authors: | Tews, I, Findeisen, F, Sinning, I, Schultz, A, Schultz, J.E, Linder, J.U. | Deposit date: | 2004-11-16 | Release date: | 2005-05-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The structure of a pH-sensing mycobacterial adenylyl cyclase holoenzyme Science, 308, 2005
|
|
4WJS
| |
4WJV
| Crystal structure of Rsa4 in complex with the Nsa2 binding peptide | Descriptor: | Maltose-binding periplasmic protein, Ribosome assembly protein 4, Ribosome biogenesis protein NSA2, ... | Authors: | Holdermann, I, Paternoga, H, Bassler, J, Hurt, E, Sinning, I. | Deposit date: | 2014-10-01 | Release date: | 2014-11-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation. J.Cell Biol., 207, 2014
|
|
4WJU
| Crystal structure of Rsa4 from Saccharomyces cerevisiae | Descriptor: | GLYCEROL, Ribosome assembly protein 4 | Authors: | Holdermann, I, Bassler, J, Hurt, E, Sinning, I. | Deposit date: | 2014-10-01 | Release date: | 2014-11-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation. J.Cell Biol., 207, 2014
|
|
4IPA
| Structure of a thermophilic Arx1 | Descriptor: | Putative curved DNA-binding protein, SULFATE ION | Authors: | Bange, G, Sinning, I. | Deposit date: | 2013-01-09 | Release date: | 2013-01-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Consistent mutational paths predict eukaryotic thermostability. BMC Evol Biol, 13, 2013
|
|