Author results

2GRC
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1.5 A STRUCTURE OF BROMODOMAIN FROM HUMAN BRG1 PROTEIN, A CENTRAL ATPASE OF SWI/SNF REMODELING COMPLEX
Descriptor:Probable global transcription activator SNF2L4
Authors:Singh, M., Popowicz, G.M., Krajewski, M., Holak, T.A.
Deposit date:2006-04-24
Release date:2007-05-08
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural ramification for acetyl-lysine recognition by the bromodomain of human BRG1 protein, a central ATPase of the SWI/SNF remodeling complex.
Chembiochem, 8, 2007
2LSL
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SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN OF TETRAHYMENA TELOMERASE PROTEIN P65
Descriptor:Telomerase associated protein p65
Authors:Singh, M., Wang, Z., Koo, B., Patel, A., Cascio, D., Collins, K., Feigon, J.
Deposit date:2012-05-01
Release date:2012-06-20
Last modified:2012-08-01
Method:SOLUTION NMR
Cite:Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65.
Mol.Cell, 47, 2012
2MNW
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SOLUTION STRUCTURE OF THE P22S MUTANT OF N-TERMINAL CS DOMAIN OF HUMAN SHQ1
Descriptor:Protein SHQ1 homolog
Authors:Singh, M., Wang, Z., Cascio, D., Feigon, J.
Deposit date:2014-04-16
Release date:2015-01-14
Last modified:2015-02-25
Method:SOLUTION NMR
Cite:Structure and Interactions of the CS Domain of Human H/ACA RNP Assembly Protein Shq1.
J.Mol.Biol., 427, 2015
3EUD
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STRUCTURE OF THE CS DOMAIN OF THE ESSENTIAL H/ACA RNP ASSEMBLY PROTEIN SHQ1P
Descriptor:Protein SHQ1
Authors:Singh, M., Cascio, D., Gonzales, F.A., Heckmann, N., Chanfreau, G., Feigon, J.
Deposit date:2008-10-09
Release date:2008-11-18
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and Functional Studies of the CS Domain of the Essential H/ACA Ribonucleoparticle Assembly Protein SHQ1.
J.Biol.Chem., 284, 2009
3MGZ
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CRYSTAL STRUCTURE OF DHBPS DOMAIN OF BI-FUNCTIONAL DHBPS/GTP CYCLOHYDROLASE II FROM MYCOBACTERIUM TUBERCULOSIS AT PH 4.0
Descriptor:3,4-dihydroxy-2-butanone 4-phosphate synthase, SULFATE ION
Authors:Singh, M., Kumar, P., Karthikeyan, S.
Deposit date:2010-04-07
Release date:2011-02-23
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis
J.Struct.Biol., 174, 2011
3MIO
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CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS AT PH 6.00
Descriptor:3,4-dihydroxy-2-butanone 4-phosphate synthase, PHOSPHATE ION, GLYCEROL, ...
Authors:Singh, M., Karthikeyan, S.
Deposit date:2010-04-11
Release date:2011-02-23
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis
J.Struct.Biol., 174, 2011
3MK5
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CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS WITH SULFATE AND ZINC AT PH 4.00
Descriptor:3,4-dihydroxy-2-butanone 4-phosphate synthase, SULFATE ION, ZINC ION
Authors:Singh, M., Karthikeyan, S.
Deposit date:2010-04-14
Release date:2011-02-23
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis
J.Struct.Biol., 174, 2011
4ERD
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF TETRAHYMENA TELOMERASE PROTEIN P65 IN COMPLEX WITH STEM IV OF TELOMERASE RNA
Descriptor:Telomerase associated protein p65, 5'-R(P*GP*GP*UP*CP*GP*AP*CP*AP*UP*CP*UP*UP*CP*GP*GP*AP*UP*GP*GP*AP*CP*C)-3', POTASSIUM ION
Authors:Singh, M., Wang, Z., Koo, B.-K., Patel, A., Cascio, D., Collins, K., Feigon, J.
Deposit date:2012-04-19
Release date:2012-06-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.589 Å)
Cite:Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65.
Mol.Cell, 47, 2012
4EYT
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF TETRAHYMENA TELOMERASE PROTEIN P65
Descriptor:Telomerase associated protein p65, SULFATE ION
Authors:Singh, M., Wang, Z., Koo, B.-K., Patel, A., Cascio, D., Collins, K., Feigon, J.
Deposit date:2012-05-01
Release date:2012-06-20
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65.
Mol.Cell, 47, 2012
4I14
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CRYSTAL STRUCTURE OF MTB-RIBA2 (RV1415)
Descriptor:Riboflavin biosynthesis protein RibBA, ZINC ION, SULFATE ION
Authors:Singh, M., Kumar, P., Yadav, S., Gautam, R., Sharma, N., Karthikeyan, S.
Deposit date:2012-11-20
Release date:2013-08-28
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure reveals the molecular mechanism of bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II (Rv1415) from Mycobacterium tuberculosis
Acta Crystallogr.,Sect.D, 69, 2013
4PBD
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CRYSTAL STRUCTURE OF THE N-TERMINAL CS DOMAIN OF HUMAN SHQ1
Descriptor:Protein SHQ1 homolog
Authors:Singh, M., Wang, Z., Cascio, D., Feigon, J.
Deposit date:2014-04-12
Release date:2015-01-14
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structure and Interactions of the CS Domain of Human H/ACA RNP Assembly Protein Shq1.
J.Mol.Biol., 427, 2015
4PCK
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CRYSTAL STRUCTURE OF THE P22S MUTANT OF N-TERMINAL CS DOMAIN OF HUMAN SHQ1
Descriptor:Protein SHQ1 homolog, GLYCEROL
Authors:Singh, M., Wang, Z., Cascio, D., Feigon, J.
Deposit date:2014-04-15
Release date:2015-01-14
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Structure and Interactions of the CS Domain of Human H/ACA RNP Assembly Protein Shq1.
J.Mol.Biol., 427, 2015
4KM6
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HUMAN FOLATE RECEPTOR ALPHA (FOLR1) AT ACIDIC PH, ORTHORHOMBIC FORM
Descriptor:Folate receptor alpha, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE
Authors:Singh, M., Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4G1P
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STRUCTURAL AND MECHANISTIC BASIS OF SUBSTRATE RECOGNITION BY NOVEL DI-PEPTIDASE DUG1P FROM SACCHAROMYCES CEREVISIAE
Descriptor:Cys-Gly metallodipeptidase DUG1, ZINC ION, GLYCINE, ...
Authors:Singh, A.K., Singh, M., Pandya, V.K., Singh, V., Mittal, M., Kumaran, S.
Deposit date:2012-07-11
Release date:2013-07-17
Last modified:2014-09-17
Method:X-RAY DIFFRACTION (2.547 Å)
Cite:Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccromyces cerevesiae
To be published
2WBC
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REFINED CRYSTAL STRUCTURE (2.3 ANGSTROM) OF A WINGED BEAN CHYMOTRYPSIN INHIBITOR AND LOCATION OF ITS SECOND REACTIVE SITE
Descriptor:CHYMOTRYPSIN INHIBITOR
Authors:Dattagupta, J.K., Podder, A., Chakrabarti, C., Sen, U., Mukhopadhyay, D., Dutta, S.K., Singh, M.
Deposit date:1997-11-26
Release date:1998-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Refined crystal structure (2.3 A) of a double-headed winged bean alpha-chymotrypsin inhibitor and location of its second reactive site.
Proteins, 35, 1999
1Y25
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STRUCTURE OF MYCOBACTERIAL THIOL PEROXIDASE TPX
Descriptor:Probable thiol peroxidase, ACETATE ION
Authors:Stehr, M., Hoffmann, B., Jger, T., Singh, M., Hecht, H.J.
Deposit date:2004-11-20
Release date:2005-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the inactive variant C60S of Mycobacterium tuberculosis thiol peroxidase
Acta Crystallogr.,Sect.D, 62, 2006
1G2C
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HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION PROTEIN CORE
Descriptor:FUSION PROTEIN (F)
Authors:Zhao, X., Singh, M., Malashkevich, V.N., Kim, P.S.
Deposit date:2000-10-18
Release date:2001-01-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural characterization of the human respiratory syncytial virus fusion protein core.
Proc.Natl.Acad.Sci.USA, 97, 2000
1JEK
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VISNA TM CORE STRUCTURE
Descriptor:ENV POLYPROTEIN
Authors:Malashkevich, V.N., Singh, M., Kim, P.S.
Deposit date:2001-06-18
Release date:2001-07-25
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The trimer-of-hairpins motif in membrane fusion: Visna virus.
Proc.Natl.Acad.Sci.USA, 98, 2001
1WBC
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CRYSTALLIZATION AND PRELIMINARY X-RAY STUDIES OF PSOPHOCARPIN B1, A CHYMOTRYPSIN INHIBITOR FROM WINGED BEAN SEEDS
Descriptor:CHYMOTRYPSIN INHIBITOR (WCI)
Authors:Dattagupta, J.K., Podder, A., Chakrabarti, C., Sen, U., Dutta, S.K., Singh, M.
Deposit date:1995-11-30
Release date:1996-04-03
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structure of a Kunitz-type chymotrypsin from winged bean seeds at 2.95 A resolution.
Acta Crystallogr.,Sect.D, 52, 1996
1ZKZ
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CRYSTAL STRUCTURE OF BMP9
Descriptor:Growth/differentiation factor 2
Authors:Brown, M.A., Zhao, Q., Baker, K.A., Naik, C., Chen, C., Pukac, L., Singh, M., Tsareva, T., Parice, Y., Mahoney, A., Roschke, V., Sanyal, I., Choe, S.
Deposit date:2005-05-04
Release date:2005-05-24
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Crystal structure of BMP-9 and functional interactions with pro-region and receptors
J.Biol.Chem., 280, 2005
3MK3
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CRYSTAL STRUCTURE OF LUMAZINE SYNTHASE FROM SALMONELLA TYPHIMURIUM LT2
Descriptor:6,7-dimethyl-8-ribityllumazine synthase, SULFATE ION
Authors:Kumar, P., Singh, M., Karthikeyan, S.
Deposit date:2010-04-14
Release date:2011-02-02
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (3.569 Å)
Cite:Crystal structure analysis of icosahedral lumazine synthase from Salmonella typhimurium, an antibacterial drug target.
Acta Crystallogr.,Sect.D, 67, 2011
3NQ4
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30MER STRUCTURE OF LUMAZINE SYNTHASE FROM SALMONELLA TYPHIMURIUM LT2
Descriptor:6,7-dimethyl-8-ribityllumazine synthase, SULFATE ION
Authors:Kumar, P., Singh, M., Karthikeyan, S.
Deposit date:2010-06-29
Release date:2011-06-08
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of Lumazine synthase from Salmonella typhimurium LT2
To be Published
1EYL
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STRUCTURE OF A RECOMBINANT WINGED BEAN CHYMOTRYPSIN INHIBITOR
Descriptor:CHYMOTRYPSIN INHIBITOR, SULFATE ION
Authors:Dattagupta, J.K., Chakrabarti, C., Ravichandran, S., Ghosh, S.
Deposit date:2000-05-07
Release date:2000-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The role of Asn14 in the stability and conformation of the reactive-site loop of winged bean chymotrypsin inhibitor: crystal structures of two point mutants Asn14-->Lys and Asn14-->Asp.
Protein Eng., 14, 2001
1FMZ
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CRYSTAL STRUCTURE OF A MUTANT WINGED BEAN CHYMOTRYPSIN INHIBITOR PROTEIN, N14K.
Descriptor:CHYMOTRYPSIN INHIBITOR 3, SULFATE ION
Authors:Dattagupta, J.K., Chakrabarti, C., Ravichandran, S., Dasgupta, J., Ghosh, S.
Deposit date:2000-08-19
Release date:2001-02-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The role of Asn14 in the stability and conformation of the reactive-site loop of winged bean chymotrypsin inhibitor: crystal structures of two point mutants Asn14-->Lys and Asn14-->Asp.
PROTEIN ENG., 14, 2001
1FN0
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STRUCTURE OF A MUTANT WINGED BEAN CHYMOTRYPSIN INHIBITOR PROTEIN, N14D.
Descriptor:CHYMOTRYPSIN INHIBITOR 3, SULFATE ION
Authors:Dattagupta, J.K., Chakrabarti, C., Ravichandran, S., Dasgupta, J., Ghosh, S.
Deposit date:2000-08-19
Release date:2001-02-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The role of Asn14 in the stability and conformation of the reactive-site loop of winged bean chymotrypsin inhibitor: crystal structures of two point mutants Asn14-->Lys and Asn14-->Asp.
PROTEIN ENG., 14, 2001