Author results

4QPZ
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CRYSTAL STRUCTURE OF THE FORMOLASE FLS_V2 IN SPACE GROUP P 21
Descriptor:Formolase, MAGNESIUM ION, THIAMINE DIPHOSPHATE
Authors:Shen, B.W., Siegel, J.B., Stoddard, B.L., Baker, D.
Deposit date:2014-06-25
Release date:2015-03-11
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Computational protein design enables a novel one-carbon assimilation pathway.
Proc.Natl.Acad.Sci.USA, 112, 2015
4QQ8
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CRYSTAL STRUCTURE OF THE FORMOLASE FLS IN SPACE GROUP P 43 21 2
Descriptor:Formolase, MAGNESIUM ION, THIAMINE DIPHOSPHATE, ...
Authors:Shen, B.W., Siegel, J.B., Stoddard, B.L.
Deposit date:2014-06-26
Release date:2015-03-11
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Computational protein design enables a novel one-carbon assimilation pathway.
Proc.Natl.Acad.Sci.USA, 112, 2015
5UX1
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PROTEIN 43 WITH ALDEHYDE DEFORMYLATING OXYGENASE ACTIVITY FROM SYNECHOCOCCUS
Descriptor:tRNA-(MS(2)IO(6)A)-hydroxylase-like, FE (III) ION
Authors:Wilson, D.K., Mak, W.S., Siegel, J.B.
Deposit date:2017-02-21
Release date:2018-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Protein 43 with aldehyde deformylating oxygenase activity from Synechococcus
To Be Published
5UX2
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PROTEIN 19 WITH ALDEHYDE DEFORMYLATING OXIDASE ACTIVITY FROM SYNECHOCOCCUS
Descriptor:Aldehyde decarbonylase, FE (III) ION, PROPANOIC ACID
Authors:Wilson, D.K., Mak, W.S., Siegel, J.B.
Deposit date:2017-02-21
Release date:2018-02-28
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Protein 19 with aldehyde deformylating oxidase activity from Synechococcus
To Be Published
5UXG
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PROTEIN 84 WITH ALDEHYDE DEFORMYLATING OXYGENASE ACTIVITY FROM SULFOLOBUS TOKODAII (MONOCLINIC)
Descriptor:aldehyde deformylating oxygenase, PHOSPHATE ION
Authors:Wilson, D.K., Mak, W.S., Siegel, J.B.
Deposit date:2017-02-22
Release date:2018-02-28
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Protein 84 with aldehyde deformylating oxygenase activity from Sulfolobus tokodaii (monoclinic)
To Be Published
5UXI
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PROTEIN 4 WITH ALDEHYDE DEFORMYLATING OXYGENASE ACTIVITY FROM NOSTOC PUNTIFORME
Descriptor:Aldehyde decarbonylase, DECYLAMINE-N,N-DIMETHYL-N-OXIDE
Authors:Wilson, D.K., Mak, W.S., Siegel, J.B.
Deposit date:2017-02-22
Release date:2018-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Protein 4 with aldehyde deformylating oxygenase activity from Nostoc puntiforme
To Be Published
5V4T
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PROTEIN 84 WITH ALDEHYDE DEFORMYLATING OXYGENASE ACTIVITY FROM SULFOLOBUS TOKODAII (ORTHORHOMBIC FORM)
Descriptor:hypothetic aldehyde deformylating oxygenase, FE (III) ION, 1,2-ETHANEDIOL
Authors:Wilson, D.K., Mak, W.S., Siegel, J.B.
Deposit date:2017-03-10
Release date:2018-03-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Protein 84 with aldehyde deformylating oxygenase activity from Sulfolobus tokodaii (orthorhombic form)
To Be Published
6D9F
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PROTEIN 60 WITH ALDEHYDE DEFORMYLATING OXIDASE ACTIVITY FROM KITASATOSPORA SETAE
Descriptor:Putative VlmB homolog, FE (III) ION, SULFATE ION, ...
Authors:Arenas, R., Wilson, D.K., Mak, W.S., Siegel, J.B.
Deposit date:2018-04-28
Release date:2019-05-08
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Protein 60 with aldehyde deformylating oxidase activity from Kitasatospora setae
To Be Published
3I1C
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CRYSTAL STRUCTURE OF A NOVEL ENGINEERED DIELS-ALDERASE: DA_20_00_A74I
Descriptor:Diisopropyl-fluorophosphatase, GLYCEROL
Authors:Lambert, A.R., Stoddard, B.L.
Deposit date:2009-06-26
Release date:2009-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction.
Science, 329, 2010
3U0S
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CRYSTAL STRUCTURE OF AN ENZYME REDESIGNED THROUGH MULTIPLAYER ONLINE GAMING: CE6
Descriptor:Diisopropyl-fluorophosphatase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ...
Authors:Bale, J.B., Shen, B.W., Stoddard, B.L.
Deposit date:2011-09-29
Release date:2012-02-01
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Increased Diels-Alderase activity through backbone remodeling guided by Foldit players.
Nat.Biotechnol., 30, 2012
4F5F
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STRUCTURE OF ASPARTATE AMINOTRANSFERASE CONVERSION TO TYROSINE AMINOTRANSFERASE: CHIMERA P1.
Descriptor:Aspartate aminotransferase
Authors:Addington, T.A., Fisher, A.J., Toney, M.D.
Deposit date:2012-05-13
Release date:2013-02-13
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4F5G
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RATIONAL DESIGN AND DIRECTED EVOLUTION OF E. COLI APARTATE AMINOTRANSFERASE TO TYROSINE AMINOTRANSFERASE: MUTANT P2.
Descriptor:Aspartate aminotransferase
Authors:Addington, T.A., Fisher, A.J., Toney, M.D.
Deposit date:2012-05-13
Release date:2013-02-13
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4F5H
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INTERCOVERSION OF SUBSTRATE SPECIFICITY: E. COLI ASPATATE AMINOTRANSFERASE TO TYROSINE AMINOTRANSFERASE: CHIMERA P3.
Descriptor:Aspartate aminotransferase
Authors:Addington, T.A., Fisher, A.J., Toney, M.D.
Deposit date:2012-05-13
Release date:2013-02-13
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4F5I
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SUBSTRATE SPECIFICITY CONVERSION OF E. COLI PYRIDOXAL-5'-PHOSPHATE DEPENDENT ASPARTATE AMINOTRANSFERASE TO TYROSINE AMINOTRANSFERASE: CHIMERA P4.
Descriptor:Aspartate aminotransferase, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Addington, T.A., Fisher, A.J., Toney, M.D.
Deposit date:2012-05-13
Release date:2013-02-13
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4F5J
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RATIONAL DESIGN AND DIRECTED EVOLUTION FOR CONVERSION OF SUBSTRATE SPECIFICITY FROM E.COLI ASPARTATE AMINOTRANSFERASE TO TYROSINE AMINOTRANSFERASE: MUTANT P5.
Descriptor:Aspartate aminotransferase
Authors:Addington, T.A., Fisher, A.J., Toney, M.D.
Deposit date:2012-05-13
Release date:2013-02-13
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (1.954 Å)
Cite:Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4F5K
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SUBSTRATE SPECIFICITY CONVERSION OF ASPARTATE AMINOTRANSFERASE TO TYROSINE AMINOTRANSFERASE BY THE JANUS ALGORITHM: CHIMERA P6.
Descriptor:Aspartate aminotransferase
Authors:Addington, T.A., Fisher, A.J., Toney, M.D.
Deposit date:2012-05-13
Release date:2013-02-13
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4F5L
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A THEORETICAL OPTIMIZED MUTANT FOR THE CONVERSION OF SUBSTRATE SPECIFICITY AND ACTIVITY OF ASPARTATE AMINOTRANSFERASE TO TYROSINE AMINOTRANSFERASE: CHIMERA P7.
Descriptor:Aspartate aminotransferase, 1,2-ETHANEDIOL
Authors:Addington, T.A., Fisher, A.J., Toney, M.D.
Deposit date:2012-05-13
Release date:2013-05-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Janus: an algorithm for ranking functional importance of residues from protein sequence alignments.
To be Published
4F5M
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WILD-TYPE E. COLI ASPARTATE AMINOTRANSFERASE: A TEMPLATE FOR THE INTERCONVERSION OF SUBSTRATE SPECIFICITY AND ACTIVITY TO TYROSINE AMINOTRANSFERASE BY THE JANUS ALGORITHM.
Descriptor:Aspartate aminotransferase, 1,2-ETHANEDIOL
Authors:Addington, T.A., Fisher, A.J., Toney, M.D.
Deposit date:2012-05-13
Release date:2013-02-13
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4NE7
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CRYSTAL STRUCTURE OF ENGINEERED KUMAMOLISIN-AS FROM ALICYCLOBACILLUS SENDAIENSIS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR367
Descriptor:Kumamolisin-As, ZINC ION
Authors:Guan, R., Pultz, I.S., Siegel, J.B., Seetharaman, J., Kornhaber, G., Maglaqui, M., Mao, L., Xiao, R., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-10-28
Release date:2013-11-20
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Northeast Structural Genomics Consortium Target OR367
To be Published
4O5S
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CRYSTAL STRUCTURE OF DIELS-ALDERASE CE11
Descriptor:Diisopropyl-fluorophosphatase
Authors:Beck, T., Preiswerk, N., Mayer, C., Hilvert, D.
Deposit date:2013-12-20
Release date:2014-06-04
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase
Proc.Natl.Acad.Sci.USA, 2014
4O5T
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CRYSTAL STRUCTURE OF DIELS-ALDERASE CE20 IN COMPLEX WITH A PRODUCT ANALOG
Descriptor:Diisopropyl-fluorophosphatase, 4-{[2-(phosphonooxy)ethyl]carbamoyl}benzyl [(1R,6S)-6-(dimethylcarbamoyl)cyclohex-2-en-1-yl]carbamate
Authors:Beck, T., Preiswerk, N., Mayer, C., Hilvert, D.
Deposit date:2013-12-20
Release date:2014-06-04
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase
Proc.Natl.Acad.Sci.USA, 2014
5UWZ
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PROTEIN 12 WITH ALDEHYDE DEFORMYLATING OXYGENASE ACTIVITY FROM GLOEOBACTER VIOLACEUS
Descriptor:Aldehyde decarbonylase, 1,2-ETHANEDIOL, STEARIC ACID
Authors:Wilson, D.K.
Deposit date:2017-02-21
Release date:2018-02-28
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Protein 12 with aldehyde deformylating oxygenase activity from Gloeobacter violaceus
To Be Published