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3T7L
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CRYSTAL STRUCTURE OF THE FYVE DOMAIN OF ENDOFIN (ZFYVE16) AT 1.1A RESOLUTION
Descriptor:Zinc finger FYVE domain-containing protein 16, ZINC ION, 1,2-ETHANEDIOL
Authors:Chaikuad, A., Williams, E., Guo, K., Sanvitale, C., Berridge, G., Krojer, T., Muniz, J.R.C., Canning, P., Phillips, C., Shrestha, A., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A., Structural Genomics Consortium (SGC)
Deposit date:2011-07-30
Release date:2011-08-31
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution
To be Published
2Y7J
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STRUCTURE OF HUMAN PHOSPHORYLASE KINASE, GAMMA 2
Descriptor:PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
Authors:Muniz, J.R.C., Shrestha, A., Savitsky, P., Wang, J., Rellos, P., Fedorov, O., Burgess-Brown, N., Brenner, B., Berridge, G., Elkins, J.M., Krojer, T., Vollmar, M., Che, K.H., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S.
Deposit date:2011-01-31
Release date:2011-02-09
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Human Phosphorylase Kinase, Gamma 2
To be Published
5UPE
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CRYSTAL STRUCTURE OF HUMAN NAMPT WITH ISOINDOLINE UREA INHIBITOR COMPOUND 5
Descriptor:Nicotinamide phosphoribosyltransferase, N-{4-[(3-phenylpropyl)carbamoyl]phenyl}-2H-isoindole-2-carboxamide
Authors:Longenecker, K.L., Raich, D., Korepanova, A.V.
Deposit date:2017-02-02
Release date:2017-06-28
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:SAR and characterization of non-substrate isoindoline urea inhibitors of nicotinamide phosphoribosyltransferase (NAMPT).
Bioorg. Med. Chem. Lett., 27, 2017
5UPF
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CRYSTAL STRUCTURE OF HUMAN NAMPT WITH ISOINDOLINE UREA INHIBITOR COMPOUND 53
Descriptor:Nicotinamide phosphoribosyltransferase, 5-fluoro-N-{4-[1-(2-hydroxy-2-methylpropanoyl)piperidin-4-yl]phenyl}-2H-isoindole-2-carboxamide
Authors:Longenecker, K.L., Raich, D., Korepanova, A.V.
Deposit date:2017-02-02
Release date:2017-06-28
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:SAR and characterization of non-substrate isoindoline urea inhibitors of nicotinamide phosphoribosyltransferase (NAMPT).
Bioorg. Med. Chem. Lett., 27, 2017
3ZEZ
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PHAGE DUTPASES CONTROL TRANSFER OF VIRULENCE GENES BY A PROTO- ONCOGENIC G PROTEIN-LIKE MECHANISM.(STAPHYLOCOCCUS BACTERIOPHAGE 80ALPHA DUTPASE WITH DUPNHPP).
Descriptor:DUTPASE, NICKEL (II) ION, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, ...
Authors:Tormo-Mas, M.A., Donderis, J., Garcia-Caballer, M., Alt, A., Mir-Sanchis, I., Marina, A., Penades, J.R.
Deposit date:2012-12-10
Release date:2013-01-30
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Phage Dutpases Control Transfer of Virulence Genes by a Proto-Oncogenic G Protein-Like Mechanism.
Mol.Cell, 49, 2013
3ZF0
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PHAGE DUTPASES CONTROL TRANSFER OF VIRULENCE GENES BY A PROTO-ONCOGENIC G PROTEIN-LIKE MECHANISM. (STAPHYLOCOCCUS BACTERIOPHAGE 80ALPHA DUTPASE D81A MUTANT WITH DUPNHPP).
Descriptor:DUTPASE, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, NICKEL (II) ION
Authors:Tormo-Mas, M.A., Donderis, J., Garcia-Caballer, M., Alt, A., Mir-Sanchis, I., Marina, A., Penades, J.R.
Deposit date:2012-12-10
Release date:2013-01-30
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Phage Dutpases Control Transfer of Virulence Genes by a Proto-Oncogenic G Protein-Like Mechanism.
Mol.Cell, 49, 2013
3ZF1
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PHAGE DUTPASES CONTROL TRANSFER OF VIRULENCE GENES BY A PROTO- ONCOGENIC G PROTEIN-LIKE MECHANISM. (STAPHYLOCOCCUS BACTERIOPHAGE 80ALPHA DUTPASE D81N MUTANT WITH DUPNHPP).
Descriptor:DUTPASE, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, NICKEL (II) ION
Authors:Tormo-Mas, M.A., Donderis, J., Garcia-Caballer, M., Alt, A., Mir-Sanchis, I., Marina, A., Penades, J.R.
Deposit date:2012-12-10
Release date:2013-01-30
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Phage Dutpases Control Transfer of Virulence Genes by a Proto-Oncogenic G Protein-Like Mechanism.
Mol.Cell, 49, 2013
3ZF2
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PHAGE DUTPASES CONTROL TRANSFER OF VIRULENCE GENES BY A PROTO- ONCOGENIC G PROTEIN-LIKE MECHANISM. (STAPHYLOCOCCUS BACTERIOPHAGE 80ALPHA DUTPASE).
Descriptor:DUTPASE, NICKEL (II) ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Tormo-Mas, M.A., Donderis, J., Garcia-Caballer, M., Alt, A., Mir-Sanchis, I., Marina, A., Penades, J.R.
Deposit date:2012-12-10
Release date:2013-01-30
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Phage Dutpases Control Transfer of Virulence Genes by a Proto-Oncogenic G Protein-Like Mechanism.
Mol.Cell, 49, 2013
3ZF3
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PHAGE DUTPASES CONTROL TRANSFER OF VIRULENCE GENES BY A PROTO-ONCOGENIC G PROTEIN-LIKE MECHANISM. (STAPHYLOCOCCUS BACTERIOPHAGE 80ALPHA DUTPASE Y84I MUTANT).
Descriptor:DUTPASE, NICKEL (II) ION
Authors:Tormo-Mas, M.A., Donderis, J., Garcia-Caballer, M., Alt, A., Mir-Sanchis, I., Marina, A., Penades, J.R.
Deposit date:2012-12-10
Release date:2013-01-30
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Phage Dutpases Control Transfer of Virulence Genes by a Proto-Oncogenic G Protein-Like Mechanism.
Mol.Cell, 49, 2013
3ZF4
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PHAGE DUTPASES CONTROL TRANSFER OF VIRULENCE GENES BY A PROTO- ONCOGENIC G PROTEIN-LIKE MECHANISM. (STAPHYLOCOCCUS BACTERIOPHAGE 80ALPHA DUTPASE Y81A MUTANT WITH DUPNHPP).
Descriptor:DUTPASE, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Tormo-Mas, M.A., Donderis, J., Garcia-Caballer, M., Alt, A., Mir-Sanchis, I., Marina, A., Penades, J.R.
Deposit date:2012-12-10
Release date:2013-01-30
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Phage Dutpases Control Transfer of Virulence Genes by a Proto-Oncogenic G Protein-Like Mechanism.
Mol.Cell, 49, 2013
3ZF5
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PHAGE DUTPASES CONTROL TRANSFER OF VIRULENCE GENES BY A PROTO-ONCOGENIC G PROTEIN-LIKE MECHANISM. (STAPHYLOCOCCUS BACTERIOPHAGE 80ALPHA DUTPASE Y84F MUTANT WITH DUPNHPP).
Descriptor:DUTPASE, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, NICKEL (II) ION, ...
Authors:Tormo-Mas, M.A., Donderis, J., Garcia-Caballer, M., Alt, A., Mir-Sanchis, I., Marina, A., Penades, J.R.
Deposit date:2012-12-10
Release date:2013-01-30
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Phage Dutpases Control Transfer of Virulence Genes by a Proto-Oncogenic G Protein-Like Mechanism.
Mol.Cell, 49, 2013
3ZF6
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PHAGE DUTPASES CONTROL TRANSFER OF VIRULENCE GENES BY A PROTO-ONCOGENIC G PROTEIN-LIKE MECHANISM. (STAPHYLOCOCCUS BACTERIOPHAGE 80ALPHA DUTPASE D81A D110C S168C MUTANT WITH DUPNHPP).
Descriptor:DUTPASE, NICKEL (II) ION, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE
Authors:Tormo-Mas, M.A., Donderis, J., Garcia-Caballer, M., Alt, A., Mir-Sanchis, I., Marina, A., Penades, J.R.
Deposit date:2012-12-10
Release date:2013-01-30
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Phage Dutpases Control Transfer of Virulence Genes by a Proto-Oncogenic G Protein-Like Mechanism.
Mol.Cell, 49, 2013