Author results

6T9N
  • Download 6t9n
  • View 6t9n
Molmil generated image of 6t9n
CRYOEM STRUCTURE OF HUMAN POLYCYSTIN-2/PKD2 IN UDM SUPPLEMENTED WITH PI(4,5)P2
Descriptor:Polycystin-2, CHOLESTEROL, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Wang, Q., Pike, A.C.W., Grieben, M., Baronina, A., Nasrallah, C., Shintre, C., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC)
Deposit date:2019-10-28
Release date:2019-11-20
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2 (PC2)
To be published
6T9O
  • Download 6t9o
  • View 6t9o
Molmil generated image of 6t9o
CRYOEM STRUCTURE OF HUMAN POLYCYSTIN-2/PKD2 IN UDM SUPPLEMENTED WITH PI(3,5)P2
Descriptor:Polycystin-2, N-ACETYL-D-GLUCOSAMINE, CHOLESTEROL, ...
Authors:Wang, Q., Pike, A.C.W., Grieben, M., Baronina, A., Nasrallah, C., Shintre, C., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC)
Deposit date:2019-10-28
Release date:2019-11-20
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2 (PC2)
Structure, 2019
6K4Y
  • Download 6k4y
  • View 6k4y
Molmil generated image of 6k4y
CRYOEM STRUCTURE OF SIGMA APPROPRIATION COMPLEX
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Shi, J., Wen, A., Feng, Y.
Deposit date:2019-05-27
Release date:2019-08-07
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.79 Å)
Cite:Structural basis of sigma appropriation.
Nucleic Acids Res., 47, 2019
6JNX
  • Download 6jnx
  • View 6jnx
Molmil generated image of 6jnx
CRYO-EM STRUCTURE OF A Q-ENGAGED ARRESTED COMPLEX
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Feng, Y., Shi, J.
Deposit date:2019-03-18
Release date:2019-06-12
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.08 Å)
Cite:Structural basis of Q-dependent transcription antitermination.
Nat Commun, 10, 2019
6JNY
  • Download 6jny
  • View 6jny
Molmil generated image of 6jny
CRYSTAL STRUCTURE OF BACTERIOPHAGE 21 Q PROTEIN
Descriptor:Antiterminator Q protein
Authors:Feng, Y., Shi, J.
Deposit date:2019-03-18
Release date:2019-06-12
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:Structural basis of Q-dependent transcription antitermination.
Nat Commun, 10, 2019
6JCX
  • Download 6jcx
  • View 6jcx
Molmil generated image of 6jcx
MYCOBACTERIUM TUBERCULOSIS TRANSCRIPTION INITIATION COMPLEX WITH ECF SIGMA FACTOR SIGMA H AND 6NT RNA
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Li, L., Zhang, Y.
Deposit date:2019-01-30
Release date:2019-05-29
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (2.903 Å)
Cite:Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
6JCY
  • Download 6jcy
  • View 6jcy
Molmil generated image of 6jcy
MYCOBACTERIUM TUBERCULOSIS RNA POLYMERASE TRANSCRIPTION INITIATION OPEN COMPLEX WITH A CHIMERIC ECF SIGMA FACTOR SIGH/E
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Li, L., Zhang, Y.
Deposit date:2019-01-30
Release date:2019-05-29
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (3.106 Å)
Cite:Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
6JBQ
  • Download 6jbq
  • View 6jbq
Molmil generated image of 6jbq
CRYOEM STRUCTURE OF ESCHERICHIA COLI SIGMAE TRANSCRIPTION INITIATION COMPLEX CONTAINING 5NT OF RNA
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Fang, C.L., Zhang, Y.
Deposit date:2019-01-26
Release date:2019-05-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
6J9E
  • Download 6j9e
  • View 6j9e
Molmil generated image of 6j9e
CRYO-EM STRUCTURE OF XANTHOMONOS ORYZAE TRANSCRIPTION ELONGATION COMPLEX WITH NUSA AND THE BACTERIOPHAGE PROTEIN P7
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:You, L.L., Zhang, Y.
Deposit date:2019-01-22
Release date:2019-07-17
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Structural basis for transcription antitermination at bacterial intrinsic terminator.
Nat Commun, 10, 2019
6J9F
  • Download 6j9f
  • View 6j9f
Molmil generated image of 6j9f
CRYO-EM STRUCTURE OF XANTHOMONOS ORYZAE TRANSCRIPTION ELONGATION COMPLEX WITH THE BACTERIOPHAGE PROTEIN P7
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:You, L.L., Zhang, Y.
Deposit date:2019-01-22
Release date:2019-07-17
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Structural basis for transcription antitermination at bacterial intrinsic terminator.
Nat Commun, 10, 2019
6J0D
  • Download 6j0d
  • View 6j0d
Molmil generated image of 6j0d
CRYSTAL STRUCTURE OF OSSUF4
Descriptor:transcription factor, ZINC ION
Authors:Wang, B., Luo, Q.
Deposit date:2018-12-24
Release date:2019-11-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The transcription factor OsSUF4 interacts with SDG725 in promoting H3K36me3 establishment.
Nat Commun, 10, 2019
6IVC
  • Download 6ivc
  • View 6ivc
Molmil generated image of 6ivc
THE FULL LENGTH OF TGEV NSP1
Descriptor:nsp1 protein
Authors:Shen, Z., Peng, G.Q.
Deposit date:2018-12-03
Release date:2019-08-07
Last modified:2019-09-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A conserved region of nonstructural protein 1 from alphacoronaviruses inhibits host gene expression and is critical for viral virulence.
J.Biol.Chem., 294, 2019
6IVD
  • Download 6ivd
  • View 6ivd
Molmil generated image of 6ivd
TGEV NSP1 MUTANT - 91-95SG
Descriptor:nsp1 mutant protein
Authors:Shen, Z., Peng, G.Q.
Deposit date:2018-12-03
Release date:2019-08-07
Last modified:2019-09-25
Method:X-RAY DIFFRACTION (1.975 Å)
Cite:A conserved region of nonstructural protein 1 from alphacoronaviruses inhibits host gene expression and is critical for viral virulence.
J.Biol.Chem., 294, 2019
6MS7
  • Download 6ms7
  • View 6ms7
Molmil generated image of 6ms7
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH A NOVEL SELECTIVE PPAR-GAMMA MODULATOR VSP-77
Descriptor:Peroxisome proliferator-activated receptor gamma, PGC1 LXXLL motif, {[(1S)-1-(4-chlorophenyl)octyl]oxy}acetic acid
Authors:Yi, W., Jiang, H., Zhou, X.E., Shi, J., Zhao, G., Zhang, X., Sun, Y., Suino-Powell, K., Li, J., Li, J., Melcher, K., Xu, H.E.
Deposit date:2018-10-16
Release date:2019-10-23
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Identification and Structural Insight of a Safe and Effective PPAR-gamma Modulator for Anti-Diabetic Drug Discovery
To Be Published
6MNL
  • Download 6mnl
  • View 6mnl
Molmil generated image of 6mnl
NMR SOLUTION STRUCTURES OF SECOND BROMODOMAIN OF BRD4 WITH FOXO3A PEPTIDE
Descriptor:FOXO3a peptide, Bromodomain-containing protein 4
Authors:Zeng, L., Zhou, M.-M.
Deposit date:2018-10-02
Release date:2018-10-31
Last modified:2018-12-19
Method:SOLUTION NMR
Cite:Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer.
Nat Commun, 9, 2018
6IGC
  • Download 6igc
  • View 6igc
Molmil generated image of 6igc
CRYSTAL STRUCTURE OF HPV58/33/52 CHIMERIC L1 PENTAMER
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Song, S., He, M.Z., Gu, Y., Li, S.W.
Deposit date:2018-09-25
Release date:2018-11-21
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Nat Commun, 9, 2018
6IGD
  • Download 6igd
  • View 6igd
Molmil generated image of 6igd
CRYSTAL STRUCTURE OF HPV58/33 CHIMERIC L1 PENTAMER
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Song, S., He, M.Z., Gu, Y., Li, S.W.
Deposit date:2018-09-25
Release date:2018-11-21
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Nat Commun, 9, 2018
6IGE
  • Download 6ige
  • View 6ige
Molmil generated image of 6ige
CRYSTAL STRUCTURE OF HUMAN PAPILLOMAVIRUS TYPE 33 PENTAMER
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Song, S., He, M.Z., Gu, Y., Li, S.W.
Deposit date:2018-09-25
Release date:2018-12-05
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Nat Commun, 9, 2018
6IGF
  • Download 6igf
  • View 6igf
Molmil generated image of 6igf
CRYSTAL STRUCTURE OF HUMAN PAPILLOMAVIRUS TYPE 52 PENTAMER
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Song, S., He, M.Z., Gu, Y., Li, S.W.
Deposit date:2018-09-25
Release date:2018-11-28
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.751 Å)
Cite:Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Nat Commun, 9, 2018
6IDI
  • Download 6idi
  • View 6idi
Molmil generated image of 6idi
CRYO-EM STRUCTURE OF IMMATURE DENGUE VIRUS SEROTYPE 3 IN COMPLEX WITH HUMAN ANTIBODY 1H10 FAB AT PH 8.0.
Descriptor:Envelope protein, Premembrane protein, Fab 1H10 heavy chain (V-region), ...
Authors:Wirawan, M., Fibriansah, G., Ng, T.S., Zhang, Q., Kostyuchenko, V.A., Shi, J., Lok, S.M.
Deposit date:2018-09-10
Release date:2018-12-12
Last modified:2019-03-13
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody.
Structure, 27, 2019
6IDK
  • Download 6idk
  • View 6idk
Molmil generated image of 6idk
CRYO-EM STRUCTURE OF IMMATURE DENGUE VIRUS SEROTYPE 3 IN COMPLEX WITH HUMAN ANTIBODY 1H10 FAB AT PH 5.0 (CLASS I PARTICLE)
Descriptor:Envelope protein, Premembrane protein, Fab 1H10 heavy chain (V-region), ...
Authors:Wirawan, M., Fibriansah, G., Ng, T.S., Zhang, Q., Kostyuchenko, V.A., Shi, J., Lok, S.M.
Deposit date:2018-09-10
Release date:2018-12-12
Last modified:2019-03-13
Method:ELECTRON MICROSCOPY (25 Å)
Cite:Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody.
Structure, 27, 2019
6IDL
  • Download 6idl
  • View 6idl
Molmil generated image of 6idl
CRYO-EM STRUCTURE OF IMMATURE DENGUE VIRUS SEROTYPE 3 IN COMPLEX WITH HUMAN ANTIBODY 1H10 FAB AT PH 5.0 (CLASS II PARTICLE)
Descriptor:Envelope protein, Premembrane protein, Fab 1H10 heavy chain (V-region), ...
Authors:Wirawan, M., Fibriansah, G., Ng, T.S., Zhang, Q., Kostyuchenko, V.A., Shi, J., Lok, S.M.
Deposit date:2018-09-10
Release date:2018-12-12
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (25 Å)
Cite:Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody.
Structure, 27, 2019
6A5F
  • Download 6a5f
  • View 6a5f
Molmil generated image of 6a5f
THE STRUCTURE OF [4+2] AND [6+4] CYCLASE IN THE BIOSYNTHETIC PATHWAY OF NARGENICIN
Descriptor:NgnD
Authors:Zhang, B., Ge, H.M.
Deposit date:2018-06-23
Release date:2019-02-06
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products.
Nature, 568, 2019
6A5G
  • Download 6a5g
  • View 6a5g
Molmil generated image of 6a5g
THE STRUCTURE OF [4+2] AND [6+4] CYCLASE IN THE BIOSYNTHETIC PATHWAY OF STREPTOSEOMYCIN
Descriptor:[4+2] and [4+6] cyclase StmD
Authors:Zhang, B., Ge, H.M.
Deposit date:2018-06-23
Release date:2019-02-06
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products.
Nature, 568, 2019
6A5H
  • Download 6a5h
  • View 6a5h
Molmil generated image of 6a5h
THE STRUCTURE OF [4+2] AND [6+4] CYCLASE IN THE BIOSYNTHETIC PATHWAY OF UNIDENTIFIED NATURAL PRODUCT
Descriptor:101015D
Authors:Zhang, B., Ge, H.M.
Deposit date:2018-06-23
Release date:2019-02-06
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (1.618 Å)
Cite:Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products.
Nature, 568, 2019