Author results

1DQ7
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THREE-DIMENSIONAL STRUCTURE OF A NEUROTOXIN FROM RED SCORPION (BUTHUS TAMULUS) AT 2.2A RESOLUTION.
分子名称:NEUROTOXIN
著者Sharma, M., Yadav, S., Karthikeyan, S., Kumar, S., Paramasivam, M., Srinivasan, A., Singh, T.P.
登録日1999-12-30
公開日2000-12-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Three-dimensional Structure of a Neurotoxin from Red Scorpion (Buthus tamulus) at 2.2A Resolution
To be Published
2L0J
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SOLID STATE NMR STRUCTURE OF THE M2 PROTON CHANNEL FROM INFLUENZA A VIRUS IN HYDRATED LIPID BILAYER
分子名称:Matrix protein 2
著者Sharma, M., Yi, M., Dong, H., Qin, H., Peterson, E., Busath, D.D., Zhou, H.X., Cross, T.A.
登録日2010-07-08
公開日2010-11-03
最終更新日2011-07-13
実験手法SOLID-STATE NMR
主引用文献Insight into the mechanism of the influenza a proton channel from a structure in a lipid bilayer.
Science, 330, 2010
5AQE
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COOPERATIVE BIO-METALLIC SELECTIVITY IN A TAILORED PROTEASE ENABLES CREATION OF A C-C CROSS-COUPLING HECKASE
分子名称:SUBTILISIN SAVINASE, (4-VINYLPHENYL)METHANESULFONIC ACID, SULFATE ION, ...
著者Sharma, M., Diaz-Rodriguez, A., Offen, W.A., Palm-Espling, M.E., Pordea, A., Wormald, M.R., Mcdonough, M., Davies, G.J., Davis, B.G.
登録日2015-09-22
公開日2015-10-07
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Bisubstrate Localisation by a Tailored Serine Protease Allows Creation of a Heck-Ase
To be Published
5ARB
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COOPERATIVE BIO-METALLIC SELECTIVITY IN A TAILORED PROTEASE ENABLES CREATION OF A C-C CROSS-COUPLING HECKASE
分子名称:SUBTILISIN SAVINASE, CALCIUM ION, GLYCEROL, ...
著者Sharma, M., Diaz-Rodriguez, A., Offen, W.A., Palm-Espling, M.E., Pordea, A., Wormald, M.R., Mcdonough, M., Davies, G.J., Davis, B.G.
登録日2015-09-24
公開日2016-09-14
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Cooperative Bio-Metallic Selectivity in a Tailored Protease Enables Creation of a C-C Cross-Coupling Heckase
To be Published
5ARC
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COOPERATIVE BIO-METALLIC SELECTIVITY IN A TAILORED PROTEASE ENABLES CREATION OF A C-C CROSS-COUPLING HECKASE
分子名称:SUBTILISIN SAVINASE, CALCIUM ION, 5-methyl-2-(5-methylpyridin-2-yl)pyridine, ...
著者Sharma, M., Diaz-Rodriguez, A., Offen, W.A., Palm-Espling, M.E., Pordea, A., Wormald, M.R., Mcdonough, M., Davies, G.J., Davis, B.G.
登録日2015-09-24
公開日2016-09-14
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Cooperative Bio-Metallic Selectivity in a Tailored Protease Enables Creation of a C-C Cross-Coupling Heckase
To be Published
5ARD
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COOPERATIVE BIO-METALLIC SELECTIVITY IN A TAILORED PROTEASE ENABLES CREATION OF A C-C CROSS-COUPLING HECKASE
分子名称:SUBTILISIN SAVINASE, CALCIUM ION, GLYCEROL, ...
著者Sharma, M., Diaz-Rodriguez, A., Offen, W.A., Palm-Espling, M.E., Pordea, A., Wormald, M.R., Mcdonough, M., Davies, G.J., Davis, B.G.
登録日2015-09-24
公開日2016-09-14
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Cooperative Bio-Metallic Selectivity in a Tailored Protease Enables Creation of a C-C Cross-Coupling Heckase
To be Published
6EOD
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STRUCTURE OF REDUCTIVE AMINASE FROM ASPERGILLUS TERREUS IN COMPLEX WITH NADPH
分子名称:Reductive Aminase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Sharma, M., Mangas-Sanchez, J., Turner, N.J., Grogan, G.
登録日2017-10-09
公開日2018-10-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Reductive Aminase from Aspergillus terreus
To Be Published
6EOH
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REDUCTIVE AMINASE FROM ASPERGILLUS TERREUS IN COMPLEX WITH NADPH AND ETHYL LEVULINATE
分子名称:Reductive Aminase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ethyl levulinate
著者Sharma, M., Grogan, G., Mangas-Sanchez, J., Turner, N.J.
登録日2017-10-09
公開日2018-10-31
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of a Reductive Aminase from Aspergillus terreus
To Be Published
6EOI
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REDUCTIVE AMINASE FROM ASPERGILLUS TERREUS IN COMPLEX WITH NADPH AND ETHYL-5-OXOHEXANOATE
分子名称:Reductive Aminase, MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Sharma, M., Mangas-Sanchez, J., Turner, N.J., Grogan, G.
登録日2017-10-09
公開日2018-10-31
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structure of Reductive Aminase from Aspergillus terreus
To Be Published
6H7P
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REDUCTIVE AMINASE FROM ASPERGILLUS TERREUS IN COMPLEX WITH NADPH4, CYCLOHEXANONE AND ALLYL AMINE
分子名称:Reductive Aminase, [[(2~{R},3~{S},4~{R},5~{R})-5-[(3~{R})-3-aminocarbonylpiperidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate, prop-2-en-1-amine, ...
著者Sharma, M., Grogan, G., Mangas-Sanchez, J., Turner, N.J.
登録日2018-07-31
公開日2019-04-03
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structure of Reductive Aminase from Aspergillus terreus
Acs Catalysis, 2018
2A7T
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CRYSTAL STRUCTURE OF A NOVEL NEUROTOXIN FROM BUTHUS TAMALUS AT 2.2A RESOLUTION.
分子名称:Neurotoxin
著者Ethayathulla, A.S., Sharma, M., Saravanan, K., Sharma, S., Kaur, P., Yadav, S., Srinivasan, A., Singh, T.P.
登録日2005-07-06
公開日2005-07-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a highly acidic neurotoxin from scorpion Buthus tamulus at 2.2A resolution reveals novel structural features.
J.Struct.Biol., 155, 2006
5OCM
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IMINE REDUCTASE FROM STREPTOSPORANGIUM ROSEUM IN COMPLEX WITH NADP+ AND 2,2,2-TRIFLUOROACETOPHENONE HYDRATE
分子名称:NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Sharma, M., Nestl, B., Grogan, G.
登録日2017-07-03
公開日2018-05-16
最終更新日2018-07-18
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献New imine-reducing enzymes from beta-hydroxyacid dehydrogenases by single amino acid substitutions.
Protein Eng. Des. Sel., 31, 2018
5OJL
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IMINE REDUCTASE FROM ASPERGILLUS TERREUS IN COMPLEX WITH NADPH4 AND DIBENZ[C,E]AZEPINE
分子名称:Imine reductase, 5-methyl-7~{H}-benzo[d][2]benzazepine, 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE
著者Sharma, M., Grogan, G.
登録日2017-07-21
公開日2018-05-30
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines.
Angew. Chem. Int. Ed. Engl., 56, 2017
5HGQ
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LOA LOA LYSYL-TRNA SYNTHETASE IN COMPLEX WITH CLADOSPORIN.
分子名称:Lysine--tRNA ligase, LYSINE, cladosporin, ...
著者Sharma, A., Sharma, M., Yogavel, M., Sharma, A.
登録日2016-01-08
公開日2016-10-26
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (3.283 Å)
主引用文献Protein Translation Enzyme lysyl-tRNA Synthetase Presents a New Target for Drug Development against Causative Agents of Loiasis and Schistosomiasis
PLoS Negl Trop Dis, 10, 2016
5ZH2
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CRYSTAL STRUCTURE OF PFKRS WITH INHIBITOR CLADO-5
分子名称:Lysine-tRNA ligase, LYSINE, (3R)-6,8-dihydroxy-3-{[(2R,6R)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one, ...
著者Babbar, P., Malhotra, N., Sharma, M., Harlos, K., Reddy, D.S., Manickam, Y., Sharma, A.
登録日2018-03-11
公開日2018-06-27
最終更新日2018-07-25
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite
J. Med. Chem., 61, 2018
5ZH3
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CRYSTAL STRUCTURE OF PFKRS WITH INHIBITOR CLADO-6
分子名称:Lysine-tRNA ligase, LYSINE, (3S)-6,8-dihydroxy-3-{[(2R,6R)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one
著者Babbar, P., Malhotra, N., Sharma, M., Harlos, K., Reddy, D.S., Manickam, Y., Sharma, A.
登録日2018-03-11
公開日2018-06-27
最終更新日2018-07-25
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite
J. Med. Chem., 61, 2018
5ZH4
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CRYSTAL STRUCTURE OF PFKRS WITH INHIBITOR CLADO-7
分子名称:Lysine-tRNA ligase, LYSINE, (3R)-6,8-dihydroxy-3-{[(2S,6R)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one, ...
著者Babbar, P., Malhotra, N., Sharma, M., Harlos, K., Reddy, D.S., Manickam, Y., Sharma, A.
登録日2018-03-11
公開日2018-06-27
最終更新日2018-07-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite
J. Med. Chem., 61, 2018
5ZH5
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CRYSTAL STRUCTURE OF PFKRS WITH INHIBITOR CLADO-2
分子名称:Lysine--tRNA ligase, LYSINE, (3S)-6,8-dihydroxy-3-{[(2R,6S)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one, ...
著者Babbar, P., Malhotra, N., Sharma, M., Harlos, K., Reddy, D.S., Manickam, Y., Sharma, A.
登録日2018-03-11
公開日2018-06-27
最終更新日2018-07-25
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite
J. Med. Chem., 61, 2018
5ZKE
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF PLASMODIUM VIVAX P43 IN SPACE GROUP P212121
分子名称:Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein p43
著者Gupta, S., Sharma, M., Harlos, K., Manickam, Y., Sharma, A.
登録日2018-03-23
公開日2019-04-24
実験手法X-RAY DIFFRACTION (1.492 Å)
主引用文献Structural analysis of aminoacyl-tRNA synthetase-interacting multifunctional proteins from plasmodium species
To Be Published
5ZKF
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF PLASMODIUM VIVAX P43 IN SPACE GROUP P21
分子名称:Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein p43
著者Gupta, S., Sharma, M., Harlos, K., Manickam, Y., Sharma, A.
登録日2018-03-23
公開日2019-04-24
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural analysis of aminoacyl-tRNA synthetase-interacting multifunctional proteins from plasmodium species
To Be Published
5ZKG
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CRYSTAL STRUCTURE OF C-TERMINAL DOMAIN OF PLASMODIUM VIVAX P43
分子名称:Aminoacyl-tRna synthetase-interacting multifunctional protein P43
著者Gupta, S., Sharma, M., Manickam, Y., Sharma, A.
登録日2018-03-23
公開日2019-04-24
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural analysis of aminoacyl-tRNA synthetase-interacting multifunctional proteins from plasmodium species
To Be Published
5AQD
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CRYSTAL STRUCTURE OF PHORMIDIUM PHYCOERYTHRIN AT PH 8.5
分子名称:PHYCOERYTHRIN ALPHA SUBUNIT, PHYCOERYTHRIN BETA SUBUNIT, PHYCOERYTHROBILIN, ...
著者Kumar, V., Sharma, M., Sonani, R.R., Gupta, G.D., Madamwar, D.
登録日2015-09-22
公開日2016-06-29
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.121 Å)
主引用文献Crystal Structure Analysis of C-Phycoerythrin from Marine Cyanobacterium Phormidium Sp. A09Dm.
Photosynth.Res., 129, 2016
5FVB
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CRYSTAL STRUCTURE OF PHORMIDIUM C-PHYCOERYTHRIN AT PH 5.0
分子名称:C-PHYCOERYTHRIN ALPHA SUBUNIT, C-PHYCOERYTHRIN BETA SUBUNIT, PHYCOERYTHROBILIN, ...
著者Kumar, V., Sonani, R.R., Sharma, M., Gupta, G.D., Madamwar, D.
登録日2016-02-05
公開日2016-06-29
最終更新日2018-04-11
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal Structure Analysis of C-Phycoerythrin from Marine Cyanobacterium Phormidium Sp. A09Dm.
Photosynth.Res., 129, 2016
2KSP
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MECHANISM FOR THE SELECTIVE INTERACTION OF C-TERMINAL EH-DOMAIN PROTEINS WITH SPECIFIC NPF-CONTAINING PARTNERS
分子名称:EH domain-containing protein 1, MICAL L1 like peptide, CALCIUM ION
著者Kieken, F., Sharma, M., Jovic, M., Giridharan, S.S., Naslavsky, N., Caplan, S., Sorgen, P.L.
登録日2010-01-11
公開日2010-01-26
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Mechanism for the selective interaction of C-terminal Eps15 homology domain proteins with specific Asn-Pro-Phe-containing partners.
J.Biol.Chem., 285, 2010
4UN2
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CRYSTAL STRUCTURE OF THE UBA DOMAIN OF DSK2 IN COMPLEX WITH UBIQUITIN
分子名称:UBIQUITIN, UBIQUITIN DOMAIN-CONTAINING PROTEIN DSK2
著者Michielssens, S., Peters, J.H., Ban, D., Pratihar, S., Seeliger, D., Sharma, M., Giller, K., Sabo, T.M., Becker, S., Lee, D., Griesinger, C., de Groot, B.L.
登録日2014-05-23
公開日2014-08-27
最終更新日2014-09-24
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献A Designed Conformational Shift to Control Protein Binding Specificity.
Angew.Chem.Int.Ed.Engl., 53, 2014
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