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3IR2
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CRYSTAL STRUCTURE OF THE APOBEC3G CATALYTIC DOMAIN
Descriptor:DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION, CHLORIDE ION, ...
Authors:Shandilya, S.M.D., Schiffer, C.A.
Deposit date:2009-08-21
Release date:2010-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of the APOBEC3G Catalytic Domain Reveals Potential Oligomerization Interfaces.
Structure, 18, 2010
3V4J
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FIRST-IN-CLASS SMALL MOLECULE INHIBITORS OF THE SINGLE-STRAND DNA CYTOSINE DEAMINASE APOBEC3G
Descriptor:DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION, 4-[methyl(nitroso)amino]benzene-1,2-diol
Authors:Shandilya, S.M.D., Ali, A., Schiffer, C.A.
Deposit date:2011-12-15
Release date:2012-02-01
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:First-In-Class Small Molecule Inhibitors of the Single-Strand DNA Cytosine Deaminase APOBEC3G.
Acs Chem.Biol., 7, 2012
3V4K
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FIRST-IN-CLASS SMALL MOLECULE INHIBITORS OF THE SINGLE-STRAND DNA CYTOSINE DEAMINASE APOBEC3G
Descriptor:DNA dC->dU-editing enzyme APOBEC-3G, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Shandilya, S.M.D., Ali, A., Schiffer, C.A.
Deposit date:2011-12-15
Release date:2012-01-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:First-In-Class Small Molecule Inhibitors of the Single-Strand DNA Cytosine Deaminase APOBEC3G.
Acs Chem.Biol., 7, 2012
2MZZ
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NMR STRUCTURE OF APOBEC3G NTD VARIANT, SNTD
Descriptor:Apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G variant, ZINC ION
Authors:Kouno, T., Luengas, E.M., Shigematu, M., Shandilya, S.M.D., Zhang, J., Chen, L., Hara, M., Schiffer, C.A., Harris, R.S., Matsuo, H.
Deposit date:2015-02-28
Release date:2015-05-13
Last modified:2015-07-01
Method:SOLUTION NMR
Cite:Structure of the Vif-binding domain of the antiviral enzyme APOBEC3G.
Nat.Struct.Mol.Biol., 22, 2015
4IOU
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CRYSTAL STRUCTURE OF THE HIV-1 VIF BINDING, CATALYTICALLY ACTIVE DOMAIN OF APOBEC3F
Descriptor:DNA dC->dU-editing enzyme APOBEC-3F, ZINC ION
Authors:Bohn, M., Shandilya, S.M.D., Schiffer, C.A.
Deposit date:2013-01-08
Release date:2013-05-29
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.751 Å)
Cite:Crystal Structure of the DNA Cytosine Deaminase APOBEC3F: The Catalytically Active and HIV-1 Vif-Binding Domain.
Structure, 21, 2013
4X1L
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STRUCTURAL BASIS FOR MUTATION-INDUCED DESTABILIZATION OF PROFILIN 1 IN ALS
Descriptor:Profilin-1, PHOSPHATE ION
Authors:Silvas, T.V., Shandilya, S.M.D., Schiffer, C.A.
Deposit date:2014-11-24
Release date:2015-06-10
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structural basis for mutation-induced destabilization of profilin 1 in ALS.
Proc.Natl.Acad.Sci.USA, 112, 2015
4X1M
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STRUCTURAL BASIS FOR MUTATION-INDUCED DESTABILIZATION OF PROFILIN 1 IN ALS
Descriptor:Profilin-1
Authors:Silvas, T.V., Shandilya, S.M.D., Schiffer, C.A.
Deposit date:2014-11-24
Release date:2015-06-10
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural basis for mutation-induced destabilization of profilin 1 in ALS.
Proc. Natl. Acad. Sci. U.S.A., 112, 2015
4X25
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STRUCTURAL BASIS FOR MUTATION-INDUCED DESTABILIZATION OF PROFILIN 1 IN ALS
Descriptor:Profilin-1
Authors:Silvas, T.V., Shandilya, S.M.D., Schiffer, C.A.
Deposit date:2014-11-25
Release date:2015-06-10
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structural basis for mutation-induced destabilization of profilin 1 in ALS.
Proc. Natl. Acad. Sci. U.S.A., 112, 2015
4XXO
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CRYSTAL STRUCTURE OF HUMAN APOBEC3A
Descriptor:DNA dC->dU-editing enzyme APOBEC-3A, ZINC ION, CHLORIDE ION
Authors:Bohn, M.F., Shandilya, S.M.D., Schiffer, C.A.
Deposit date:2015-01-30
Release date:2015-04-29
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.843 Å)
Cite:The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization.
Structure, 23, 2015
5KEG
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CRYSTAL STRUCTURE OF APOBEC3A IN COMPLEX WITH A SINGLE-STRANDED DNA
Descriptor:DNA dC->dU-editing enzyme APOBEC-3A, DNA (5'-D(*TP*TP*CP*TP*T)-3'), ZINC ION, ...
Authors:Kouno, T., Hilbert, B.J., Silvas, T., Royer, W.E., Matsuo, H., Schiffer, C.A.
Deposit date:2016-06-09
Release date:2017-05-10
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity.
Nat Commun, 8, 2017