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5EG7
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BU of 5eg7 by Molmil
The cap binding site of influenza virus protein PB2 as a drug target
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL, Polymerase basic protein 2
Authors:Severin, C, Rocha de Moura, T, Liu, Y, Li, K, Zheng, X, Luo, M.
Deposit date:2015-10-26
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The cap-binding site of influenza virus protein PB2 as a drug target.
Acta Crystallogr D Struct Biol, 72, 2016
5EG9
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BU of 5eg9 by Molmil
The cap binding site of influenza virus protein PB2 as a drug target
Descriptor: Polymerase basic protein 2
Authors:Severin, C, Rocha de Moura, T, Liu, Y, Li, K, Zheng, X, Luo, M.
Deposit date:2015-10-26
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The cap-binding site of influenza virus protein PB2 as a drug target.
Acta Crystallogr D Struct Biol, 72, 2016
5EG8
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BU of 5eg8 by Molmil
The cap binding site of influenza virus protein PB2 as a drug target
Descriptor: Polymerase basic protein 2, THIOCYANATE ION
Authors:Liu, Y, Zheng, X, Severin, C, Rocha de Moura, T, Li, K, Luo, M.
Deposit date:2015-10-26
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:The cap-binding site of influenza virus protein PB2 as a drug target.
Acta Crystallogr D Struct Biol, 72, 2016
5WOP
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BU of 5wop by Molmil
High Resolution Structure of Mutant CA09-PB2cap
Descriptor: GLYCEROL, Polymerase PB2
Authors:Constantinides, A.E, Gumpper, R.H, Severin, C, Luo, M.
Deposit date:2017-08-02
Release date:2017-12-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:High-resolution structure of the Influenza A virus PB2cap binding domain illuminates the changes induced by ligand binding.
Acta Crystallogr F Struct Biol Commun, 74, 2018
6W4K
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BU of 6w4k by Molmil
Crystal structure of Lysine Specific Demethylase 1 (LSD1) with CC-90011
Descriptor: 4-[2-(4-aminopiperidin-1-yl)-5-(3-fluoro-4-methoxyphenyl)-1-methyl-6-oxo-1,6-dihydropyrimidin-4-yl]-2-fluorobenzonitrile, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A, ...
Authors:Hosfield, D.J.
Deposit date:2020-03-11
Release date:2020-10-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Discovery of CC-90011: A Potent and Selective Reversible Inhibitor of Lysine Specific Demethylase 1 (LSD1).
J.Med.Chem., 63, 2020

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