Author results

1THG
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1.8 ANGSTROMS REFINED STRUCTURE OF THE LIPASE FROM GEOTRICHUM CANDIDUM
Descriptor:Lipase 2, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE
Authors:Schrag, J.D., Cygler, M.
Deposit date:1992-07-28
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:1.8 A refined structure of the lipase from Geotrichum candidum.
J.Mol.Biol., 230, 1993
1JHN
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CRYSTAL STRUCTURE OF THE LUMENAL DOMAIN OF CALNEXIN
Descriptor:calnexin, CALCIUM ION
Authors:Schrag, J.D., Bergeron, J.M., Li, Y., Borisova, S., Hahn, M., Thomas, D.Y., Cygler, M.
Deposit date:2001-06-28
Release date:2001-10-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Structure of calnexin, an ER chaperone involved in quality control of protein folding.
Mol.Cell, 8, 2001
2LIP
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PSEUDOMONAS LIPASE OPEN CONFORMATION
Descriptor:LIPASE, CALCIUM ION
Authors:Schrag, J.D., Cygler, M.
Deposit date:1996-12-13
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The open conformation of a Pseudomonas lipase.
Structure, 5, 1997
3CG6
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CRYSTAL STRUCTURE OF GADD45 GAMMA
Descriptor:Growth arrest and DNA-damage-inducible 45 gamma
Authors:Schrag, J.D., Jiralerspong, S., Banville, M., Jaramillo, M.L., O'Connor-McCourt, M.D.
Deposit date:2008-03-05
Release date:2008-04-29
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure and dimerization interface of GADD45gamma.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2ZL1
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MP1-P14 SCAFFOLDING COMPLEX
Descriptor:Mitogen-activated protein kinase kinase 1-interacting protein 1, Mitogen-activated protein-binding protein-interacting protein
Authors:Schrag, J.D., Cygler, M., Munger, C., Magloire, A.
Deposit date:2008-04-02
Release date:2008-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular dynamics-solvated interaction energy studies of protein-protein interactions: the MP1-p14 scaffolding complex.
J.Mol.Biol., 379, 2008
3CPT
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MP1-P14 SCAFFOLDING COMPLEX
Descriptor:Mitogen-activated protein kinase kinase 1-interacting protein 1, Mitogen-activated protein-binding protein-interacting protein
Authors:Schrag, J.D., Cygler, M., Munger, C., Magloire, A.
Deposit date:2008-04-01
Release date:2008-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular dynamics-solvated interaction energy studies of protein-protein interactions: the MP1-p14 scaffolding complex.
J.Mol.Biol., 379, 2008
3IA2
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PSEUDOMONAS FLUORESCENS ESTERASE COMPLEXED TO THE R-ENANTIOMER OF A SULFONATE TRANSITION STATE ANALOG
Descriptor:Arylesterase, (2R)-butane-2-sulfonate, GLYCEROL, ...
Authors:Schrag, J.D., Kazlauskas, R.J., Jiang, Y., Morley, K.
Deposit date:2009-07-13
Release date:2010-07-21
Last modified:2011-09-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Different active-site loop orientation in serine hydrolases versus acyltransferases.
Chembiochem, 12, 2011
3HEA
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THE L29P/L124I MUTATION OF PSEUDOMONAS FLUORESCENS ESTERASE
Descriptor:Arylesterase, GLYCEROL, SULFATE ION, ...
Authors:Kazlauskas, R.J., Schrag, J.D., Cheeseman, J.D., Morley, K.L.
Deposit date:2009-05-08
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Switching catalysis from hydrolysis to perhydrolysis in Pseudomonas fluorescens esterase.
Biochemistry, 49, 2010
1EEA
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ACETYLCHOLINESTERASE
Descriptor:PROTEIN (ACETYLCHOLINESTERASE)
Authors:Raves, M.L., Giles, K., Schrag, J.D., Schmid, M.F., Phillips Jr., G.N., Wah, C., Howard, A.J., Silman, I., Sussman, J.L.
Deposit date:1999-01-26
Release date:1999-02-01
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Quaternary Structure of Tetrameric Acetylcholinesterase
Structure and Function of Cholinesterases and Related Proteins, 1998
1VA4
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PSEUDOMONAS FLUORESCENS ARYL ESTERASE
Descriptor:Arylesterase, GLYCEROL
Authors:Cheeseman, J.D., Tocilj, A., Park, S., Schrag, J.D., Kazlauskas, R.J.
Deposit date:2004-02-11
Release date:2004-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.804 Å)
Cite:Structure of an aryl esterase from Pseudomonas fluorescens.
Acta Crystallogr.,Sect.D, 60, 2004
1FC4
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2-AMINO-3-KETOBUTYRATE COA LIGASE
Descriptor:2-AMINO-3-KETOBUTYRATE CONENZYME A LIGASE, 2-AMINO-3-KETOBUTYRIC ACID, PYRIDOXAL-5'-PHOSPHATE
Authors:Schmidt, A., Matte, A., Li, Y., Sivaraman, J., Larocque, R., Schrag, J.D., Smith, C., Sauve, V., Cygler, M., Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2000-07-17
Release date:2001-05-02
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of 2-amino-3-ketobutyrate CoA ligase from Escherichia coli complexed with a PLP-substrate intermediate: inferred reaction mechanism.
Biochemistry, 40, 2001
1IJI
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CRYSTAL STRUCTURE OF L-HISTIDINOL PHOSPHATE AMINOTRANSFERASE WITH PLP
Descriptor:Histidinol Phosphate Aminotransferase, PYRIDOXAL-5'-PHOSPHATE
Authors:Sivaraman, J., Li, Y., Larocque, R., Schrag, J.D., Cygler, M., Matte, A.
Deposit date:2001-04-26
Release date:2001-08-29
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of histidinol phosphate aminotransferase (HisC) from Escherichia coli, and its covalent complex with pyridoxal-5'-phosphate and l-histidinol phosphate.
J.Mol.Biol., 311, 2001
1KAE
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L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH L-HISTIDINOL (SUBSTRATE), ZINC AND NAD (COFACTOR)
Descriptor:Histidinol dehydrogenase, SULFATE ION, ZINC ION, ...
Authors:Barbosa, J.A.R.G., Sivaraman, J., Li, Y., Larocque, R., Matte, A., Schrag, J.D., Cygler, M.
Deposit date:2001-11-01
Release date:2002-06-12
Last modified:2015-06-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
1KAH
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L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH L-HISTIDINE (PRODUCT), ZN AND NAD (COFACTOR)
Descriptor:Histidinol dehydrogenase, ZINC ION, HISTIDINE
Authors:Barbosa, J.A.R.G., Sivaraman, J., Li, Y., Larocque, R., Matte, A., Schrag, J.D., Cygler, M.
Deposit date:2001-11-02
Release date:2002-06-12
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
1KAR
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L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH HISTAMINE (INHIBITOR), ZINC AND NAD (COFACTOR)
Descriptor:Histidinol dehydrogenase, ZINC ION, HISTAMINE
Authors:Barbosa, J.A.R.G., Sivaraman, J., Li, Y., Larocque, R., Matte, A., Schrag, J.D., Cygler, M.
Deposit date:2001-11-02
Release date:2002-06-12
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
1KSK
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STRUCTURE OF RSUA
Descriptor:RIBOSOMAL SMALL SUBUNIT PSEUDOURIDINE SYNTHASE A, URACIL
Authors:Sivaraman, J., Sauve, V., Larocque, R., Stura, E.A., Schrag, J.D., Cygler, M., Matte, A.
Deposit date:2002-01-13
Release date:2002-04-24
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP.
Nat.Struct.Biol., 9, 2002
1KSL
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STRUCTURE OF RSUA
Descriptor:RIBOSOMAL SMALL SUBUNIT PSEUDOURIDINE SYNTHASE A, URACIL
Authors:Sivaraman, J., Sauve, V., Larocque, R., Stura, E.A., Schrag, J.D., Cygler, M., Matte, A., Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2002-01-13
Release date:2002-04-24
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP.
Nat.Struct.Biol., 9, 2002
1KSV
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STRUCTURE OF RSUA
Descriptor:RIBOSOMAL SMALL SUBUNIT PSEUDOURIDINE SYNTHASE A, URIDINE-5'-MONOPHOSPHATE
Authors:Sivaraman, J., Sauve, V., Larocque, R., Stura, E.A., Schrag, J.D., Cygler, M., Matte, A.
Deposit date:2002-01-14
Release date:2002-04-24
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP.
Nat.Struct.Biol., 9, 2002
1Q18
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CRYSTAL STRUCTURE OF E.COLI GLUCOKINASE (GLK)
Descriptor:Glucokinase
Authors:Lunin, V.V., Li, Y., Schrag, J.D., Matte, A., Cygler, M., Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2003-07-18
Release date:2004-07-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Crystal structures of Escherichia coli ATP-dependent glucokinase and its complex with glucose.
J.Bacteriol., 186, 2004
1SSL
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SOLUTION STRUCTURE OF THE PSI DOMAIN FROM THE MET RECEPTOR
Descriptor:Hepatocyte growth factor receptor
Authors:Kozlov, G., Perreault, A., Schrag, J.D., Cygler, M., Gehring, K., Ekiel, I.
Deposit date:2004-03-24
Release date:2004-10-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Insights into function of PSI domains from structure of the Met receptor PSI domain.
Biochem.Biophys.Res.Commun., 321, 2004
1SZ2
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CRYSTAL STRUCTURE OF E. COLI GLUCOKINASE IN COMPLEX WITH GLUCOSE
Descriptor:Glucokinase, BETA-D-GLUCOSE
Authors:Lunin, V.V., Li, Y., Schrag, J.D., Iannuzzi, P., Matte, A., Cygler, M.
Deposit date:2004-04-02
Release date:2004-11-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of Escherichia coli ATP-dependent glucokinase and its complex with glucose
J.Bacteriol., 186, 2004
1YNF
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CRYSTAL STRUCTURE OF N-SUCCINYLARGININE DIHYDROLASE, ASTB, BOUND TO SUBSTRATE AND PRODUCT, AN ENZYME FROM THE ARGININE CATABOLIC PATHWAY OF ESCHERICHIA COLI
Descriptor:Succinylarginine dihydrolase, POTASSIUM ION
Authors:Tocilj, A., Schrag, J.D., Li, Y., Schneider, B.L., Reitzer, L., Matte, A., Cygler, M.
Deposit date:2005-01-24
Release date:2005-02-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of N-succinylarginine dihydrolase AstB, bound to substrate and product, an enzyme from the arginine catabolic pathway of Escherichia coli.
J.Biol.Chem., 280, 2005
1YNH
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CRYSTAL STRUCTURE OF N-SUCCINYLARGININE DIHYDROLASE, ASTB, BOUND TO SUBSTRATE AND PRODUCT, AN ENZYME FROM THE ARGININE CATABOLIC PATHWAY OF ESCHERICHIA COLI
Descriptor:Succinylarginine Dihydrolase, POTASSIUM ION, N~2~-(3-CARBOXYPROPANOYL)-L-ORNITHINE
Authors:Tocilj, A., Schrag, J.D., Li, Y., Schneider, B.L., Reitzer, L., Matte, A., Cygler, M.
Deposit date:2005-01-24
Release date:2005-03-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of N-succinylarginine dihydrolase AstB, bound to substrate and product, an enzyme from the arginine catabolic pathway of Escherichia coli.
J.Biol.Chem., 280, 2005
1YNI
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CRYSTAL STRUCTURE OF N-SUCCINYLARGININE DIHYDROLASE, ASTB, BOUND TO SUBSTRATE AND PRODUCT, AN ENZYME FROM THE ARGININE CATABOLIC PATHWAY OF ESCHERICHIA COLI
Descriptor:Succinylarginine Dihydrolase, POTASSIUM ION, N~2~-(3-CARBOXYPROPANOYL)-L-ARGININE
Authors:Tocilj, A., Schrag, J.D., Li, Y., Schneider, B.L., Reitzer, L., Matte, A., Cygler, M., Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2005-01-24
Release date:2005-02-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of N-succinylarginine dihydrolase AstB, bound to substrate and product, an enzyme from the arginine catabolic pathway of Escherichia coli.
J.Biol.Chem., 280, 2005
1YS1
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BURKHOLDERIA CEPACIA LIPASE COMPLEXED WITH HEXYLPHOSPHONIC ACID (R)-2-METHYL-3-PHENYLPROPYL ESTER
Descriptor:Lipase, CALCIUM ION, HEXYLPHOSPHONIC ACID (R)-2-METHYL-3-PHENYLPROPYL ESTER
Authors:Mezzetti, A., Schrag, J.D., Cheong, C.S., Kazlauskas, R.J.
Deposit date:2005-02-06
Release date:2005-05-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Mirror-Image Packing in Enantiomer Discrimination Molecular Basis for the Enantioselectivity of B.cepacia Lipase toward 2-Methyl-3-Phenyl-1-Propanol.
Chem.Biol., 12, 2005
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