Author results

5J0H
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DE NOVO DESIGN OF PROTEIN HOMO-OLIGOMERS WITH MODULAR HYDROGEN BOND NETWORK-MEDIATED SPECIFICITY
Descriptor:Design construct 2L6HC3_13
Authors:Sankaran, B., Zwart, P.H., Pereira, J.H., Baker, D., Boyken, S., Chen, Z., Groves, B., Langan, R.A., Oberdorfer, G., Ford, A., Gilmore, J., Xu, C., DiMaio, F., Seelig, G.
Deposit date:2016-03-28
Release date:2016-05-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
5J0I
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DE NOVO DESIGN OF PROTEIN HOMO-OLIGOMERS WITH MODULAR HYDROGEN BOND NETWORK-MEDIATED SPECIFICITY
Descriptor:Designed protein 2L6HC3_12
Authors:Sankaran, B., Zwart, P.H., Pereira, J.H., Baker, D., Boyken, S., Chen, Z., Groves, B., Langan, R.A., Oberdorfer, G., Ford, A., Gilmore, J., Xu, C., DiMaio, F., Seelig, G.
Deposit date:2016-03-28
Release date:2016-05-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
5J0J
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DE NOVO DESIGN OF PROTEIN HOMO-OLIGOMERS WITH MODULAR HYDROGEN BOND NETWORK-MEDIATED SPECIFICITY
Descriptor:designed protein 2L6HC3_6
Authors:Sankaran, B., Zwart, P.H., Pereira, J.H., Baker, D., Boyken, S., Chen, Z., Groves, B., Langan, R.A., Oberdorfer, G., Ford, A., Gilmore, J., Xu, C., DiMaio, F., Seelig, G.
Deposit date:2016-03-28
Release date:2016-05-25
Method:X-RAY DIFFRACTION (2.256 Å)
Cite:De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
5J0K
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DE NOVO DESIGN OF PROTEIN HOMO-OLIGOMERS WITH MODULAR HYDROGEN BOND NETWORK-MEDIATED SPECIFICITY
Descriptor:designed protein 2L4HC2_23
Authors:Sankaran, B., Zwart, P.H., Pereira, J.H., Baker, D., Boyken, S., Chen, Z., Groves, B., Langan, R.A., Oberdorfer, G., Ford, A., Gilmore, J., Xu, C., DiMaio, F., Seelig, G.
Deposit date:2016-03-28
Release date:2016-05-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
5J0L
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DE NOVO DESIGN OF PROTEIN HOMO-OLIGOMERS WITH MODULAR HYDROGEN BOND NETWORK-MEDIATED SPECIFICITY
Descriptor:designed protein 3L6HC2_2
Authors:Sankaran, B., Zwart, P.H., Pereira, J.H., Baker, D., Boyken, S., Chen, Z., Groves, B., Langan, R.A., Oberdorfer, G., Ford, A., Gilmore, J., Xu, C., DiMaio, F., Seelig, G.
Deposit date:2016-03-28
Release date:2016-07-06
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
5J10
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DE NOVO DESIGN OF PROTEIN HOMO-OLIGOMERS WITH MODULAR HYDROGEN BOND NETWORK-MEDIATED SPECIFICITY
Descriptor:peptide design 2L4HC2_24
Authors:Sankaran, B., Zwart, P.H., Pereira, J.H., Baker, D., Boyken, S., Chen, Z., Groves, B., Langan, R.A., Oberdorfer, G., Ford, A., Gilmore, J., Xu, C., DiMaio, F., Seelig, G.
Deposit date:2016-03-28
Release date:2016-05-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
5J2L
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DE NOVO DESIGN OF PROTEIN HOMO-OLIGOMERS WITH MODULAR HYDROGEN BOND NETWORK-MEDIATED SPECIFICITY
Descriptor:protein design 2L4HC2_11
Authors:Sankaran, B., Zwart, P.H., Pereira, J.H., Baker, D., Boyken, S., Chen, Z., Groves, B., Langan, R.A., Oberdorfer, G., Ford, A., Gilmore, J., Xu, C., DiMaio, F., Seelig, G.
Deposit date:2016-03-29
Release date:2016-05-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
5J73
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DE NOVO DESIGN OF PROTEIN HOMO-OLIGOMERS WITH MODULAR HYDROGEN BOND NETWORK-MEDIATED SPECIFICITY
Descriptor:protein design 2L4HC2_9
Authors:Sankaran, B., Zwart, P.H., Pereira, J.H., Baker, D., Boyken, S., Chen, Z., Groves, B., Langan, R.A., Oberdorfer, G., Ford, A., Gilmore, J., Xu, C., DiMaio, F., Seelig, G.
Deposit date:2016-04-05
Release date:2016-05-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
5IZS
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DE NOVO DESIGN OF PROTEIN HOMO-OLIGOMERS WITH MODULAR HYDROGEN BOND NETWORK-MEDIATED SPECIFICITY
Descriptor:Designed protein 5L6HC3_1
Authors:Sankaran, B., Zwart, P.H., Pereira, J.H., Baker, D., Boyken, S., Chen, Z., Oberdorfer, G.
Deposit date:2016-03-25
Release date:2016-05-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
5JQZ
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DESIGNED TWO-RING HOMOTETRAMER AT 3.8A RESOLUTION
Descriptor:De novo designed homotetramer
Authors:Sankaran, B., Zwart, P.H., Pereira, J.H., Baker, D., Oberdorfer, G., Boyken, S.E., Chen, Z.
Deposit date:2016-05-05
Release date:2016-06-29
Method:X-RAY DIFFRACTION (3.83 Å)
Cite:De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
5EIL
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COMPUTATIONAL DESIGN OF A HIGH-AFFINITY METALLOPROTEIN HOMOTRIMER CONTAINING A METAL CHELATING NON-CANONICAL AMINO ACID
Descriptor:TRI-05, FE (III) ION
Authors:Sankaran, B., Zwart, P.H., Mills, J.H., Pereira, J.H., Baker, D.
Deposit date:2015-10-30
Release date:2016-11-16
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Computational design of a homotrimeric metalloprotein with a trisbipyridyl core.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5K7V
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COMPUTATIONAL DESIGN OF SELF-ASSEMBLING CYCLIC PROTEIN HOMOOLIGOMERS
Descriptor:Designed protein HR00C3
Authors:Sankaran, B., Zwart, P.H., Fallas, J.A., Pereira, J.H., Ueda, G., Baker, D.
Deposit date:2016-05-26
Release date:2017-04-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.165 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
Nat Chem, 9, 2017
5KBA
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COMPUTATIONAL DESIGN OF SELF-ASSEMBLING CYCLIC PROTEIN HOMOOLIGOMERS
Descriptor:Designed protein ANK1C2
Authors:Sankaran, B., Zwart, P.H., Fallas, J.A., Pereira, J.H., Ueda, G., Baker, D.
Deposit date:2016-06-02
Release date:2017-04-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
Nat Chem, 9, 2017
4FS8
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THE STRUCTURE OF AN AS(III) S-ADENOSYLMETHIONINE METHYLTRANSFERASE: INSIGHTS INTO THE MECHANISM OF ARSENIC BIOTRANSFORMATION
Descriptor:Arsenic methyltransferase, CALCIUM ION
Authors:Ajees, A.A., Marapakala, K., Packianathan, C., Sankaran, B., Rosen, B.P.
Deposit date:2012-06-27
Release date:2012-07-11
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure of an As(III) S-Adenosylmethionine Methyltransferase: Insights into the Mechanism of Arsenic Biotransformation.
Biochemistry, 51, 2012
3PMO
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THE STRUCTURE OF LPXD FROM PSEUDOMONAS AERUGINOSA AT 1.3 A RESOLUTION
Descriptor:UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, 1,2-ETHANEDIOL, CHLORIDE ION
Authors:Badger, J., Chie-Leon, B., Logan, C., Sridhar, V., Sankaran, B., Zwart, P.H., Nienaber, V.
Deposit date:2010-11-17
Release date:2011-07-27
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The structure of LpxD from Pseudomonas aeruginosa at 1.3 A resolution.
Acta Crystallogr.,Sect.F, 67, 2011
4E6T
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STRUCTURE OF LPXA FROM ACINETOBACTER BAUMANNII AT 1.8A RESOLUTION (P212121 FORM)
Descriptor:Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, CITRATE ANION
Authors:Badger, J., Chie-Leon, B., Logan, C., Sridhar, V., Sankaran, B., Zwart, P.H., Nienaber, V.
Deposit date:2012-03-15
Release date:2012-12-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure determination of LpxA from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 68, 2012
4E6U
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STRUCTURE OF LPXA FROM ACINETOBACTER BAUMANNII AT 1.4A RESOLUTION (P63 FORM)
Descriptor:Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, SULFATE ION, 1,2-ETHANEDIOL
Authors:Badger, J., Chie-Leon, B., Logan, C., Sridhar, V., Sankaran, B., Zwart, P.H., Nienaber, V.
Deposit date:2012-03-16
Release date:2012-12-12
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structure determination of LpxA from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 68, 2012
4E75
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STRUCTURE OF LPXD FROM ACINETOBACTER BAUMANNII AT 2.85A RESOLUTION (P21 FORM)
Descriptor:UDP-3-O-acylglucosamine N-acyltransferase
Authors:Badger, J., Chie-Leon, B., Logan, C., Sridhar, V., Sankaran, B., Zwart, P.H., Nienaber, V.
Deposit date:2012-03-16
Release date:2013-01-16
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure determination of LpxD from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 69, 2013
4E79
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STRUCTURE OF LPXD FROM ACINETOBACTER BAUMANNII AT 2.66A RESOLUTION (P4322 FORM)
Descriptor:UDP-3-O-acylglucosamine N-acyltransferase
Authors:Badger, J., Chie-Leon, B., Logan, C., Sridhar, V., Sankaran, B., Zwart, P.H., Nienaber, V.
Deposit date:2012-03-16
Release date:2013-01-16
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Structure determination of LpxD from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 69, 2013
4S2L
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CRYSTAL STRUCTURE OF OXA-163 BETA-LACTAMASE
Descriptor:Beta-lactamase, SODIUM ION
Authors:Stojanoski, V., Liya, H., Palzkill, T.G., Prasad, B., Sankaran, B.
Deposit date:2015-01-21
Release date:2015-07-22
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural Basis for Different Substrate Profiles of Two Closely Related Class D beta-Lactamases and Their Inhibition by Halogens.
Biochemistry, 54, 2015
5L33
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN WITH CURVED BETA-SHEET
Descriptor:denovo NTF2
Authors:Oberdorfer, G., Marcos, E., Basanta, B., Chidyausiku, T.M., Sankaran, B., Baker, D.
Deposit date:2016-08-03
Release date:2017-01-25
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5TPH
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN HOMODIMER WITH CURVED BETA-SHEET
Descriptor:de novo NTF2 homodimer, DI(HYDROXYETHYL)ETHER, CHLORIDE ION
Authors:Basanta, B., Marcos, E., Oberdorfer, G., Chidyausiku, T.M., Sankaran, B., Baker, D.
Deposit date:2016-10-20
Release date:2017-01-25
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5TPJ
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN WITH CURVED BETA-SHEET
Descriptor:denovo NTF2
Authors:Basanta, B., Oberdorfer, G., Marcos, E., Chidyausiku, T.M., Sankaran, B., Baker, D.
Deposit date:2016-10-20
Release date:2017-01-25
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5TRV
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN WITH CURVED BETA-SHEET
Descriptor:denovo NTF2, DI(HYDROXYETHYL)ETHER
Authors:Basanta, B., Oberdorfer, G., Marcos, E., Chidyausiku, T.M., Sankaran, B., Baker, D.
Deposit date:2016-10-27
Release date:2017-01-25
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5TS4
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN WITH CURVED BETA-SHEET
Descriptor:denovo NTF2, DI(HYDROXYETHYL)ETHER
Authors:Basanta, B., Oberdorfer, G., Chidyausiku, T.M., Marcos, E., Pereira, J.H., Sankaran, B., Zwart, P.H., Baker, D.
Deposit date:2016-10-27
Release date:2017-01-25
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017