6AMW
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6AMV
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2MS4
| Cyclophilin a complexed with a fragment of crk-ii | Descriptor: | Peptide, Peptidyl-prolyl cis-trans isomerase A | Authors: | Jankowski, W, Saleh, T, Rossi, P, Kalodimos, C. | Deposit date: | 2014-07-22 | Release date: | 2015-09-09 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Cyclophilin A promotes cell migration via the Abl-Crk signaling pathway. Nat.Chem.Biol., 12, 2016
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2L3S
| Structure of the autoinhibited Crk | Descriptor: | Autoinhibited Crk protein | Authors: | Kalodimos, C.G, Sarkar, P, Saleh, T, Tzeng, S.R, Birge, R. | Deposit date: | 2010-09-21 | Release date: | 2010-12-08 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis for regulation of the Crk signaling protein by a proline switch. Nat.Chem.Biol., 7, 2011
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2LQN
| Solution structure of CRKL | Descriptor: | Crk-like protein | Authors: | Jankowski, W, Saleh, T, Kalodimos, C. | Deposit date: | 2012-03-09 | Release date: | 2012-05-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII. Nat.Chem.Biol., 8, 2012
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2L3Q
| Structure of the prolyl trans isomer of the Crk Protein | Descriptor: | Trans isomer of Crk protein | Authors: | Kalodimos, C, Sarkar, P, Saleh, T, Tzeng, S, Birge, R. | Deposit date: | 2010-09-21 | Release date: | 2010-12-08 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis for regulation of the Crk signaling protein by a proline switch. Nat.Chem.Biol., 7, 2011
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6XRG
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6XR6
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6XR7
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2LQW
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2L3P
| Structure of the prolyl cis isomer of the Crk Protein | Descriptor: | Cis isomer of Crk protein | Authors: | Kalodimos, C.G, Sarkar, P, Saleh, T, Tzeng, S.R, Birge, R. | Deposit date: | 2010-09-21 | Release date: | 2010-12-08 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis for regulation of the Crk signaling protein by a proline switch. Nat.Chem.Biol., 7, 2011
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7N9G
| Crystal structure of the Abl 1b Kinase domain in complex with Dasatinib and Imatinib | Descriptor: | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, PHOSPHATE ION, ... | Authors: | Miller, D.J, Xie, T. | Deposit date: | 2021-06-17 | Release date: | 2022-04-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Imatinib can act as an Allosteric Activator of Abl Kinase. J.Mol.Biol., 434, 2022
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