2ZUH
 
 | | Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant (D297A) | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Camphor 5-monooxygenase, ... | | Authors: | Sakurai, K, Harada, K, Shimada, H, Shimokata, K, Hayashi, T, Tsukihara, T. | | Deposit date: | 2008-10-18 | | Release date: | 2009-10-20 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant
to be published
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2ZUI
 | | Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant (D297N) | | Descriptor: | CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | | Authors: | Sakurai, K, Harada, K, Shimada, H, Shimokata, K, Hayashi, T, Tsukihara, T. | | Deposit date: | 2008-10-18 | | Release date: | 2009-10-20 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant
TO BE PUBLISHED
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2ZUJ
 | | Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant(D297L) | | Descriptor: | CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | | Authors: | Sakurai, K, Harada, K, Shimada, H, Shimokata, K, Hayashi, T, Tsukihara, T. | | Deposit date: | 2008-10-18 | | Release date: | 2009-10-20 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant
to be published
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2ZWT
 | | Crystal Structure of Ferric Cytochrome P450cam | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Camphor 5-monooxygenase, ... | | Authors: | Sakurai, K, Shimada, H, Hayashi, T, Tsukihara, T. | | Deposit date: | 2008-12-18 | | Release date: | 2009-02-17 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Substrate binding induces structural changes in cytochrome P450cam
Acta Crystallogr.,Sect.F, 65, 2009
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2ZWU
 | | Crystal Structure of Camphor Soaked Ferric Cytochrome P450cam | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Camphor 5-monooxygenase, ... | | Authors: | Sakurai, K, Shimada, H, Hayashi, T, Tsukihara, T. | | Deposit date: | 2008-12-18 | | Release date: | 2009-02-17 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Substrate binding induces structural changes in cytochrome P450cam
Acta Crystallogr.,Sect.F, 65, 2009
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2GV2
 | | MDM2 in complex with an 8-mer p53 peptide analogue | | Descriptor: | 8-MER P53 PEPTIDE ANALOGUE, E3 ubiquitin-protein ligase Mdm2 | | Authors: | Schubert, C, Sakurai, K. | | Deposit date: | 2006-05-02 | | Release date: | 2006-09-05 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystallographic Analysis of an 8-mer p53 Peptide Analogue Complexed with MDM2.
J.Am.Chem.Soc., 128, 2006
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6IIA
 | | MexB in complex with LMNG | | Descriptor: | Lauryl Maltose Neopentyl Glycol, Multidrug resistance protein MexB | | Authors: | Nakashima, R, Sakurai, K, Nakao, K. | | Deposit date: | 2018-10-04 | | Release date: | 2019-03-27 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | Crystal structures of multidrug efflux pump MexB bound with high-molecular-mass compounds.
Sci Rep, 9, 2019
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2ZAX
 | | Crystal Structure of Ferric Cytochrome P450cam | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Cytochrome P450-cam, ... | | Authors: | Sakurai, K, Shimada, H, Harada, K, Hayashi, T, Tsukihara, T. | | Deposit date: | 2007-10-11 | | Release date: | 2008-01-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Evaluation of the functional role of the heme-6-propionate side chain in cytochrome P450cam
J.Am.Chem.Soc., 130, 2008
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3W9I
 | | Structural basis for the inhibition of bacterial multidrug exporters | | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Multidrug resistance protein MexB | | Authors: | Sakurai, K, Nakashima, R, Hayashi, K, Yamaguchi, A. | | Deposit date: | 2013-04-04 | | Release date: | 2013-07-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Structural basis for the inhibition of bacterial multidrug exporters
Nature, 500, 2013
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3W9J
 | | Structural basis for the inhibition of bacterial multidrug exporters | | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Multidrug resistance protein MexB, [{2-[({[(3R)-1-{8-[(4-tert-butyl-1,3-thiazol-2-yl)carbamoyl]-4-oxo-3-[(E)-2-(1H-tetrazol-5-yl)ethenyl]-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidin-3-yl]oxy}carbonyl)amino]ethyl}(dimethyl)ammonio]acetate | | Authors: | Sakurai, K, Nakashima, R, Hayashi, K, Yamaguchi, A. | | Deposit date: | 2013-04-04 | | Release date: | 2013-07-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Structural basis for the inhibition of bacterial multidrug exporters
Nature, 500, 2013
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3W9H
 | | Structural basis for the inhibition of bacterial multidrug exporters | | Descriptor: | Acriflavine resistance protein B, [{2-[({[(3R)-1-{8-[(4-tert-butyl-1,3-thiazol-2-yl)carbamoyl]-4-oxo-3-[(E)-2-(1H-tetrazol-5-yl)ethenyl]-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidin-3-yl]oxy}carbonyl)amino]ethyl}(dimethyl)ammonio]acetate | | Authors: | Sakurai, K, Nagata, C, Nakashima, R, Yamaguchi, A. | | Deposit date: | 2013-04-04 | | Release date: | 2013-07-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Structural basis for the inhibition of bacterial multidrug exporters
Nature, 500, 2013
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3VVZ
 | | Crystal Strucuture of The Rhodamine 6G-Bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | Descriptor: | Putative regulatory protein, RHODAMINE 6G, SULFATE ION | | Authors: | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | | Deposit date: | 2012-07-30 | | Release date: | 2013-07-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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3VVY
 | | Crystal Strucuture of The Ethidium-Bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | Descriptor: | ETHIDIUM, Putative regulatory protein | | Authors: | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | | Deposit date: | 2012-07-30 | | Release date: | 2013-07-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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3VVX
 | | Crystal Strucuture of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | Descriptor: | Putative regulatory protein, SULFATE ION | | Authors: | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | | Deposit date: | 2012-07-30 | | Release date: | 2013-07-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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3VW1
 | | Crystal Strucuture of the Crystal Violet-Bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | Descriptor: | CHLORIDE ION, CRYSTAL VIOLET, Putative regulatory protein, ... | | Authors: | Sakurai, K, Yamasaki, S, Nakashima, R, Nikaido, E, Yamaguchi, A, Nishino, K. | | Deposit date: | 2012-07-30 | | Release date: | 2013-07-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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3VW0
 | | Crystal Structure of The Dequalinum-bound Form of RamR (Transcriptional Regulator of TetR Family) From Salmonella Typhimurium | | Descriptor: | DEQUALINIUM, Putative regulatory protein, SULFATE ION | | Authors: | Sakurai, K, Yamasaki, S, Nakashima, R, Nikaido, E, Yamaguchi, A, Nishino, K. | | Deposit date: | 2012-07-30 | | Release date: | 2013-07-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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3VW2
 | | Crystal Strucuture of The Berberine-bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | Descriptor: | BERBERINE, Putative regulatory protein, SULFATE ION | | Authors: | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | | Deposit date: | 2012-07-30 | | Release date: | 2013-07-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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5YIL
 | | Hoisting-loop in bacterial multidrug exporter AcrB is a highly flexible hinge that enables the large motion of the subdomains | | Descriptor: | Multidrug efflux pump subunit AcrB | | Authors: | Zwama, M, Sakurai, K, Hayashi, K, Nakashima, R, Kitagawa, K, Nishino, K, Yamaguchi, A. | | Deposit date: | 2017-10-05 | | Release date: | 2017-11-15 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Hoisting-Loop in Bacterial Multidrug Exporter AcrB Is a Highly Flexible Hinge That Enables the Large Motion of the Subdomains.
Front Microbiol, 8, 2017
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3AOD
 | | Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket | | Descriptor: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, Acriflavine resistance protein B, RIFAMPICIN | | Authors: | Nakashima, R, Sakurai, K, Yamaguchi, A. | | Deposit date: | 2010-09-23 | | Release date: | 2011-11-30 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket
Nature, 480, 2011
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3AOA
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3AOB
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3AOC
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6IE9
 | | RamR in complex with chenodeoxycholic acid | | Descriptor: | CHENODEOXYCHOLIC ACID, Regulatory protein, SULFATE ION | | Authors: | Nakashima, R, Sakurai, K, Yamasaki, S, Nishino, K. | | Deposit date: | 2018-09-13 | | Release date: | 2019-02-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Crystal structure of the multidrug resistance regulator RamR complexed with bile acids.
Sci Rep, 9, 2019
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6IE8
 | | RamR in complex with cholic acid | | Descriptor: | CHOLIC ACID, Regulatory protein, SULFATE ION | | Authors: | Nakashima, R, Sakurai, K, Yamasaki, S, Nishino, K. | | Deposit date: | 2018-09-13 | | Release date: | 2019-02-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the multidrug resistance regulator RamR complexed with bile acids.
Sci Rep, 9, 2019
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5Y01
 | | Acid-tolerant monomeric GFP, Gamillus, non-fluorescence (OFF) state | | Descriptor: | Green fluorescent protein, PHOSPHATE ION | | Authors: | Nakashima, R, Sakurai, K, Shinoda, H, Matsuda, T, Nagai, T. | | Deposit date: | 2017-07-14 | | Release date: | 2018-01-17 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Acid-Tolerant Monomeric GFP from Olindias formosa.
Cell Chem Biol, 25, 2018
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