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5IR6
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BU of 5ir6 by Molmil
The structure of bd oxidase from Geobacillus thermodenitrificans
Descriptor: Bd-type quinol oxidase subunit I, Bd-type quinol oxidase subunit II, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, ...
Authors:Safarian, S, Mueller, H, Rajendran, C, Preu, J, Ovchinnikov, S, Kusumoto, T, Hirose, T, Langer, J, Sakamoto, J, Michel, H.
Deposit date:2016-03-12
Release date:2016-05-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure of a bd oxidase indicates similar mechanisms for membrane-integrated oxygen reductases.
Science, 352, 2016
5DOQ
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BU of 5doq by Molmil
The structure of bd oxidase from Geobacillus thermodenitrificans
Descriptor: Bd-type quinol oxidase subunit I, Bd-type quinol oxidase subunit II, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, ...
Authors:Safarian, S, Mueller, H, Rajendran, C, Preu, J, Ovchinnikov, S, Kusumoto, T, Hirose, T, Langer, J, Sakamoto, J, Michel, H.
Deposit date:2015-09-11
Release date:2016-05-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structure of a bd oxidase indicates similar mechanisms for membrane-integrated oxygen reductases.
Science, 352, 2016
7NKZ
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BU of 7nkz by Molmil
Cryo-EM structure of the cytochrome bd oxidase from M. tuberculosis at 2.5 A resolution
Descriptor: CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, HEME B/C, MENAQUINONE-9, ...
Authors:Safarian, S, Wu, D, Krause, K.L, Michel, H.
Deposit date:2021-02-19
Release date:2021-09-22
Last modified:2021-09-29
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB.
Nat Commun, 12, 2021
6RKO
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BU of 6rko by Molmil
Cryo-EM structure of the E. coli cytochrome bd-I oxidase at 2.68 A resolution
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Cytochrome bd-I ubiquinol oxidase subunit 1, ...
Authors:Safarian, S, Hahn, A, Kuehlbrandt, W, Michel, H.
Deposit date:2019-04-30
Release date:2019-10-16
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Active site rearrangement and structural divergence in prokaryotic respiratory oxidases.
Science, 366, 2019
6FHZ
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BU of 6fhz by Molmil
Inward-facing conformation of a multidrug resistance MATE family transporter of the MOP superfamily.
Descriptor: Putative MOP flippase
Authors:Zakrzewska, S, Safarian, S, Michel, H.
Deposit date:2018-01-16
Release date:2019-05-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Inward-facing conformation of a multidrug resistance MATE family transporter.
Proc.Natl.Acad.Sci.USA, 116, 2019
7OY2
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BU of 7oy2 by Molmil
High resolution structure of cytochrome bd-II oxidase from E. coli
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[(2~{E},6~{E},10~{Z},14~{E},18~{E},22~{E},26~{E})-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaenyl]naphthalene-1,4-dione, CARDIOLIPIN, ...
Authors:Grund, T.N, Wu, D, Bald, D, Michel, H, Safarian, S.
Deposit date:2021-06-23
Release date:2021-12-15
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.06 Å)
Cite:Mechanistic and structural diversity between cytochrome bd isoforms of Escherichia coli .
Proc.Natl.Acad.Sci.USA, 118, 2021
8QCZ
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BU of 8qcz by Molmil
Cryo-EM structure of the outward-facing heme-bound FLVCR2
Descriptor: Heme transporter FLVCR2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Weng, T.-H, Wu, D, Safarian, S.
Deposit date:2023-08-28
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of the outward-facing heme-bound FLVCR2
To Be Published
8QCS
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BU of 8qcs by Molmil
Cryo-EM structure of the inward-facing FLVCR1
Descriptor: Heme transporter FLVCR1
Authors:Weng, T.-H, Wu, D, Safarian, S.
Deposit date:2023-08-28
Release date:2024-04-17
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular mechanism of choline and ethanolamine transport in humans.
Nature, 630, 2024
8QCT
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BU of 8qct by Molmil
Cryo-EM structure of the inward-facing choline-bound FLVCR1
Descriptor: CHOLINE ION, Heme transporter FLVCR1
Authors:Weng, T.-H, Wu, D, Safarian, S.
Deposit date:2023-08-28
Release date:2024-04-17
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Molecular mechanism of choline and ethanolamine transport in humans.
Nature, 630, 2024
8QCX
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BU of 8qcx by Molmil
Cryo-EM structure of the inward-facing FLVCR2
Descriptor: Heme transporter FLVCR2
Authors:Weng, T.-H, Wu, D, Safarian, S.
Deposit date:2023-08-28
Release date:2024-04-17
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular mechanism of choline and ethanolamine transport in humans.
Nature, 630, 2024
8QCY
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BU of 8qcy by Molmil
Cryo-EM structure of the outward-facing FLVCR2
Descriptor: Heme transporter FLVCR2
Authors:Weng, T.-H, Wu, D, Safarian, S.
Deposit date:2023-08-28
Release date:2024-04-17
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular mechanism of choline and ethanolamine transport in humans.
Nature, 630, 2024
8QD0
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BU of 8qd0 by Molmil
Cryo-EM structure of the inward-facing choline-bound FLVCR2
Descriptor: CHOLINE ION, Heme transporter FLVCR2
Authors:Weng, T.-H, Wu, D, Safarian, S.
Deposit date:2023-08-28
Release date:2024-04-17
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Molecular mechanism of choline and ethanolamine transport in humans.
Nature, 630, 2024
8R8T
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BU of 8r8t by Molmil
Cryo-EM structure of the inward-facing ethanolamine-bound FLVCR1
Descriptor: ETHANOLAMINE, Heme transporter FLVCR1
Authors:Weng, T.-H, Wu, D, Safarian, S.
Deposit date:2023-11-29
Release date:2024-04-17
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular mechanism of choline and ethanolamine transport in humans.
Nature, 630, 2024
6YUZ
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BU of 6yuz by Molmil
Homodimeric structure of the rBAT complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neutral and basic amino acid transport protein rBAT
Authors:Wu, D, Safarian, S, Michel, H.
Deposit date:2020-04-27
Release date:2021-01-20
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis for amino acid exchange by a human heteromeric amino acid transporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6YV1
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BU of 6yv1 by Molmil
Structure of human b(0,+)AT1
Descriptor: b(0,+)-type amino acid transporter 1
Authors:Wu, D, Safarian, S, Michel, H.
Deposit date:2020-04-27
Release date:2021-01-20
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for amino acid exchange by a human heteromeric amino acid transporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6YUP
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BU of 6yup by Molmil
Heterotetrameric structure of the rBAT-b(0,+)AT1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neutral and basic amino acid transport protein rBAT, ...
Authors:Wu, D, Safarian, S, Michel, H.
Deposit date:2020-04-27
Release date:2021-01-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for amino acid exchange by a human heteromeric amino acid transporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6GWH
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BU of 6gwh by Molmil
Outward-facing conformation of a multidrug resistance MATE family transporter of the MOP superfamily.
Descriptor: MOP transporter
Authors:Zakrzewska, S, Safarian, S, Michel, H.
Deposit date:2018-06-25
Release date:2019-06-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Inward-facing conformation of a multidrug resistance MATE family transporter.
Proc.Natl.Acad.Sci.USA, 116, 2019
6HFB
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BU of 6hfb by Molmil
Outward-facing conformation of a multidrug resistance MATE family transporter of the MOP superfamily.
Descriptor: CESIUM ION, Uncharacterized protein
Authors:Nonaka, T, Zakrzewska, S, Safarian, S, Michel, H.
Deposit date:2018-08-21
Release date:2019-06-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.495 Å)
Cite:Inward-facing conformation of a multidrug resistance MATE family transporter.
Proc.Natl.Acad.Sci.USA, 116, 2019
6Z71
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BU of 6z71 by Molmil
Structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state
Descriptor: Aq128
Authors:Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H.
Deposit date:2020-05-29
Release date:2021-12-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The structure of the Aquifex aeolicus MATE family multidrug resistance transporter and sequence comparisons suggest the existence of a new subfamily.
Proc.Natl.Acad.Sci.USA, 118, 2021
6Z70
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BU of 6z70 by Molmil
Structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Aq128
Authors:Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H.
Deposit date:2020-05-29
Release date:2021-12-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of the Aquifex aeolicus MATE family multidrug resistance transporter and sequence comparisons suggest the existence of a new subfamily.
Proc.Natl.Acad.Sci.USA, 118, 2021
6FV6
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BU of 6fv6 by Molmil
Monomer structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state
Descriptor: Aq128
Authors:Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H.
Deposit date:2018-03-01
Release date:2019-03-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Monomer structure of Aq128 in the outward-facing state
To Be Published
6FV8
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BU of 6fv8 by Molmil
Dimer structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state
Descriptor: Aq128
Authors:Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H.
Deposit date:2018-03-01
Release date:2019-03-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Dimer structure of the MATE family multidrug resistance transporter Aq128 in the outward-facing state
To Be Published
6FV7
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BU of 6fv7 by Molmil
Dimer structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state
Descriptor: Aq128
Authors:Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H.
Deposit date:2018-03-01
Release date:2019-03-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Dimer structure of Aq128 in the outward-facing state
To Be Published
7AU6
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BU of 7au6 by Molmil
Cytochrome c oxidase structure in O-state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, COPPER (II) ION, ...
Authors:Kolbe, F, Safarian, S, Michel, H.
Deposit date:2020-11-02
Release date:2021-12-01
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Cytochrome c oxidase structure in O-state
To Be Published
7ATN
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BU of 7atn by Molmil
Cytochrome c oxidase structure in R-state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, COPPER (II) ION, ...
Authors:Kolbe, F, Safarian, S, Michel, H.
Deposit date:2020-10-30
Release date:2021-12-01
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Cytochrome c oxidase structure in R-state
To Be Published

 

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