1MAM | |
1LYD | |
1EXP | | BETA-1,4-GLYCANASE CEX-CD | | Descriptor: | BETA-1,4-D-GLYCANASE CEX-CD, BETA-D-GLUCOSE, 2-deoxy-2-fluoro-alpha-D-glucopyranose | | Authors: | White, A., Tull, D., Johns, K.L., Withers, S.G., Rose, D.R. | | Deposit date: | 1996-01-11 | | Release date: | 1997-01-27 | | Last modified: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystallographic observation of a covalent catalytic intermediate in a beta-glycosidase.
Nat.Struct.Biol., 3, 1996
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1MVU | |
1RRO | | REFINEMENT OF RECOMBINANT ONCOMODULIN AT 1.30 ANGSTROMS RESOLUTION | | Descriptor: | RAT ONCOMODULIN, CALCIUM ION | | Authors: | Ahmed, F.R., Rose, D.R., Evans, S.V., Pippy, M.E., To, R. | | Deposit date: | 1992-08-27 | | Release date: | 1993-10-31 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Refinement of recombinant oncomodulin at 1.30 A resolution.
J.Mol.Biol., 230, 1993
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2HIS | | CELLULOMONAS FIMI XYLANASE/CELLULASE DOUBLE MUTANT E127A/H205N WITH COVALENT CELLOBIOSE | | Descriptor: | CELLULOMONAS FIMI FAMILY 10 BETA-1,4-GLYCANASE, BETA-D-GLUCOSE, ALPHA-D-GLUCOSE | | Authors: | Notenboom, V., Birsan, C., Nitz, M., Rose, D.R., Warren, R.A.J., Wither, S.G. | | Deposit date: | 1998-02-23 | | Release date: | 1998-10-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Insights into transition state stabilization of the beta-1,4-glycosidase Cex by covalent intermediate accumulation in active site mutants.
Nat.Struct.Biol., 5, 1998
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1PLG | | EVIDENCE FOR THE EXTENDED HELICAL NATURE OF POLYSACCHARIDE EPITOPES. THE 2.8 ANGSTROMS RESOLUTION STRUCTURE AND THERMODYNAMICS OF LIGAND BINDING OF AN ANTIGEN BINDING FRAGMENT SPECIFIC FOR ALPHA-(2->8)-POLYSIALIC ACID | | Descriptor: | IGG2A=KAPPA= | | Authors: | Evans, S.V., Sigurskjold, B.W., Jennings, H.J., Brisson, J.-R., Tse, W.C., To, R., Altman, E., Frosch, M., Weisgerber, C., Kratzin, H., Klebert, S., Vaesen, M., Bitter-Suermann, D., Rose, D.R., Young, N.M., Bundle, D.R. | | Deposit date: | 1995-04-24 | | Release date: | 1996-04-03 | | Last modified: | 2012-02-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Evidence for the extended helical nature of polysaccharide epitopes. The 2.8 A resolution structure and thermodynamics of ligand binding of an antigen binding fragment specific for alpha-(2-->8)-polysialic acid.
Biochemistry, 34, 1995
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1BLN | | ANTI-P-GLYCOPROTEIN FAB MRK-16 | | Descriptor: | PROTEIN (MONOCLONAL ANTIBODY MRK-16 (LIGHT CHAIN)), PROTEIN (MONOCLONAL ANTIBODY MRK-16 (HEAVY CHAIN)) | | Authors: | Vasudevan, S., Tsuruo, T., Rose, D.R. | | Deposit date: | 1998-07-16 | | Release date: | 1998-10-28 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Mode of binding of anti-P-glycoprotein antibody MRK-16 to its antigen. A crystallographic and molecular modeling study.
J.Biol.Chem., 273, 1998
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1OMD | | STRUCTURE OF ONCOMODULIN REFINED AT 1.85 ANGSTROMS RESOLUTION. AN EXAMPLE OF EXTENSIVE MOLECULAR AGGREGATION VIA CA2+ | | Descriptor: | ONCOMODULIN, CALCIUM ION | | Authors: | Ahmed, F.R., Przybylska, M., Rose, D.R., Birnbaum, G.I., Pippy, M.E., Macmanus, J.P. | | Deposit date: | 1990-04-19 | | Release date: | 1991-07-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structure of oncomodulin refined at 1.85 A resolution. An example of extensive molecular aggregation via Ca2+.
J.Mol.Biol., 216, 1990
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2AP2 | |
6FAB | | THREE-DIMENSIONAL STRUCTURE OF MURINE ANTI-P-AZOPHENYLARSONATE FAB 36-71. 1. X-RAY CRYSTALLOGRAPHY, SITE-DIRECTED MUTAGENESIS, AND MODELING OF THE COMPLEX WITH HAPTEN | | Descriptor: | IGG1-KAPPA 36-71 FAB (LIGHT CHAIN), IGG1-KAPPA 36-71 FAB (HEAVY CHAIN) | | Authors: | Strong, R.K., Rose, D.R., Petsko, G.A., Sharon, J., Margolies, M.N. | | Deposit date: | 1991-01-17 | | Release date: | 1993-01-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Three-dimensional structure of murine anti-p-azophenylarsonate Fab 36-71. 1. X-ray crystallography, site-directed mutagenesis, and modeling of the complex with hapten.
Biochemistry, 30, 1991
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1AP2 | | SINGLE CHAIN FV OF C219 | | Descriptor: | MONOCLONAL ANTIBODY C219 | | Authors: | Hoedemaeker, P.J., Rose, D.R. | | Deposit date: | 1997-07-23 | | Release date: | 1997-12-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | A single chain Fv fragment of P-glycoprotein-specific monoclonal antibody C219. Design, expression, and crystal structure at 2.4 A resolution.
J.Biol.Chem., 272, 1997
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1FH7 | | CRYSTAL STRUCTURE OF THE XYLANASE CEX WITH XYLOBIOSE-DERIVED INHIBITOR DEOXYNOJIRIMYCIN | | Descriptor: | BETA-1,4-XYLANASE, BETA-D-XYLOPYRANOSE, PIPERIDINE-3,4,5-TRIOL | | Authors: | Notenboom, V., Williams, S.J., Hoos, R., Withers, S.G., Rose, D.R. | | Deposit date: | 2000-07-31 | | Release date: | 2000-08-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Detailed structural analysis of glycosidase/inhibitor interactions: complexes of Cex from Cellulomonas fimi with xylobiose-derived aza-sugars.
Biochemistry, 39, 2000
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1FH8 | | CRYSTAL STRUCTURE OF THE XYLANASE CEX WITH XYLOBIOSE-DERIVED ISOFAGOMINE INHIBITOR | | Descriptor: | BETA-1,4-XYLANASE, BETA-D-XYLOPYRANOSE, PIPERIDINE-3,4-DIOL | | Authors: | Notenboom, V., Williams, S.J., Hoos, R., Withers, S.G., Rose, D.R. | | Deposit date: | 2000-07-31 | | Release date: | 2000-08-23 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Detailed structural analysis of glycosidase/inhibitor interactions: complexes of Cex from Cellulomonas fimi with xylobiose-derived aza-sugars.
Biochemistry, 39, 2000
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1FH9 | | CRYSTAL STRUCTURE OF THE XYLANASE CEX WITH XYLOBIOSE-DERIVED LACTAM OXIME INHIBITOR | | Descriptor: | BETA-1,4-XYLANASE, BETA-D-XYLOPYRANOSE, 3,4,5-TRIHYDOXY-PIPERIDINE-2-ONE-OXIME | | Authors: | Notenboom, V., Williams, S.J., Hoos, R., Withers, S.G., Rose, D.R. | | Deposit date: | 2000-07-31 | | Release date: | 2000-08-23 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Detailed structural analysis of glycosidase/inhibitor interactions: complexes of Cex from Cellulomonas fimi with xylobiose-derived aza-sugars.
Biochemistry, 39, 2000
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1FHD | | CRYSTAL STRUCTURE OF THE XYLANASE CEX WITH XYLOBIOSE-DERIVED IMIDAZOLE INHIBITOR | | Descriptor: | BETA-1,4-XYLANASE, BETA-D-XYLOPYRANOSE, 5,6,7,8-TETRAHYDRO-IMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL | | Authors: | Notenboom, V., Williams, S.J., Hoos, R., Withers, S.G., Rose, D.R. | | Deposit date: | 2000-07-31 | | Release date: | 2000-08-23 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Detailed structural analysis of glycosidase/inhibitor interactions: complexes of Cex from Cellulomonas fimi with xylobiose-derived aza-sugars.
Biochemistry, 39, 2000
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1HTY | | GOLGI ALPHA-MANNOSIDASE II | | Descriptor: | ALPHA-MANNOSIDASE II, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ... | | Authors: | van den Elsen, J.M.H., Kuntz, D.A., Rose, D.R. | | Deposit date: | 2001-01-02 | | Release date: | 2002-01-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.
EMBO J., 20, 2001
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1HWW | | GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH SWAINSONINE | | Descriptor: | ALPHA-MANNOSIDASE II, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ... | | Authors: | van den Elsen, J.M.H., Kuntz, D.A., Rose, D.R. | | Deposit date: | 2001-01-10 | | Release date: | 2002-01-10 | | Last modified: | 2018-04-04 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.
EMBO J., 20, 2001
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1HXK | | GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH DEOXYMANNOJIRIMICIN | | Descriptor: | ALPHA-MANNOSIDASE II, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ... | | Authors: | van den Elsen, J.M.H., Kuntz, D.A., Rose, D.R. | | Deposit date: | 2001-01-16 | | Release date: | 2002-01-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.
EMBO J., 20, 2001
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1HZF | | C4ADG FRAGMENT OF HUMAN COMPLEMENT FACTOR C4A | | Descriptor: | COMPLEMENT FACTOR C4A | | Authors: | van den Elsen, J.M.H., Martin, A., Wong, V., Clemenza, L., Rose, D.R., Isenman, D.E. | | Deposit date: | 2001-01-24 | | Release date: | 2002-10-09 | | Last modified: | 2018-04-04 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | X-ray crystal structure of the C4d fragment of human complement component C4.
J.Mol.Biol., 322, 2002
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1I82 | | FAMILY 9 CARBOHYDRATE-BINDING MODULE FROM THERMOTOGA MARITIMA XYLANASE 10A WITH CELLOBIOSE | | Descriptor: | ENDO-1,4-BETA-XYLANASE A, BETA-D-GLUCOSE, CALCIUM ION | | Authors: | Notenboom, V., Boraston, A.B., Warren, R.A.J., Kilburn, D.G., Rose, D.R. | | Deposit date: | 2001-03-12 | | Release date: | 2001-06-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structures of the family 9 carbohydrate-binding module from Thermotoga maritima xylanase 10A in native and ligand-bound forms.
Biochemistry, 40, 2001
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1I8A | | FAMILY 9 CARBOHYDRATE-BINDING MODULE FROM THERMOTOGA MARITIMA XYLANASE 10A WITH GLUCOSE | | Descriptor: | ENDO-1,4-BETA-XYLANASE A, BETA-D-GLUCOSE, CALCIUM ION | | Authors: | Notenboom, V., Boraston, A.B., Warren, R.A.J., Kilburn, D.G., Rose, D.R. | | Deposit date: | 2001-03-12 | | Release date: | 2001-06-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structures of the family 9 carbohydrate-binding module from Thermotoga maritima xylanase 10A in native and ligand-bound forms.
Biochemistry, 40, 2001
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1I8U | | FAMILY 9 CARBOHYDRATE-BINDING MODULE FROM THERMOTOGA MARITIMA XYLANASE 10A | | Descriptor: | ENDO-1,4-BETA-XYLANASE A, CALCIUM ION | | Authors: | Notenboom, V., Boraston, A.B., Warren, R.A.J., Kilburn, D.G., Rose, D.R. | | Deposit date: | 2001-03-16 | | Release date: | 2001-06-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structures of the family 9 carbohydrate-binding module from Thermotoga maritima xylanase 10A in native and ligand-bound forms.
Biochemistry, 40, 2001
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1J01 | | CRYSTAL STRUCTURE OF THE XYLANASE CEX WITH XYLOBIOSE-DERIVED INHIBITOR ISOFAGOMINE LACTAM | | Descriptor: | beta-1,4-xylanase, 3-HYDROXY-4-(3,4,5-TRIHYDROXY-TETRAHYDRO-PYRAN-2-YLOXY)-PIPERIDIN-2-ONE | | Authors: | Williams, S.J., Notenboom, V., Wicki, J., Rose, D.R., Withers, S.G. | | Deposit date: | 2002-10-25 | | Release date: | 2002-11-06 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A New, Simple, High-Affinity Glycosidase Inhibitor: Analysis of Binding through X-ray Crystallography, Mutagenesis, and Kinetic Analysis
J.Am.Chem.Soc., 122, 2000
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1J83 | | STRUCTURE OF FAM17 CARBOHYDRATE BINDING MODULE FROM CLOSTRIDIUM CELLULOVORANS | | Descriptor: | ENDO-1,4-BETA GLUCANASE ENGF, CALCIUM ION | | Authors: | Notenboom, V., Boraston, A.B., Chiu, P., Freelove, A.C.J., Kilburn, D.G., Rose, D.R. | | Deposit date: | 2001-05-20 | | Release date: | 2001-12-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Recognition of cello-oligosaccharides by a family 17 carbohydrate-binding module: an X-ray crystallographic, thermodynamic and mutagenic study.
J.Mol.Biol., 314, 2001
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