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5JQX
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CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH PHOSPHOGLYCERIC ACID (PGA) - GPGS*PGA
Descriptor:Glucosyl-3-phosphoglycerate synthase, 3-PHOSPHOGLYCERIC ACID
Authors:Albesa-Jove, D., Sancho-Vaello, E., Rodrigo-Unzueta, A., Comino, N., Carreras-Gonzalez, A., Arrasate, P., Urresti, S., Guerin, M.E.
Deposit date:2016-05-05
Release date:2017-05-24
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS.
Structure, 25, 2017
5JSX
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CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MN2+ AND URIDINE-DIPHOSPHATE-GLUCOSE (UDP-GLC)
Descriptor:glucosyl-3-phosphoglycerate synthase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE-GLUCOSE, ...
Authors:Albesa-Jove, D., Sancho-Vaello, E., Rodrigo-Unzueta, A., Comino, N., Carreras-Gonzalez, A., Arrasate, P., Urresti, S., Guerin, M.E.
Deposit date:2016-05-09
Release date:2017-05-24
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS.
Structure, 25, 2017
5JT0
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CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MN2+, URIDINE-DIPHOSPHATE (UDP) AND GLUCOSYL-3-PHOSPHOGLYCERATE (GPG) - GPGS*GPG*UDP*MN2+
Descriptor:Glucosyl-3-phosphoglycerate synthase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ...
Authors:Albesa-Jove, D., Sancho-Vaello, E., Rodrigo-Unzueta, A., Comino, N., Carreras-Gonzalez, A., Arrasate, P., Urresti, S., Guerin, M.E.
Deposit date:2016-05-09
Release date:2017-05-24
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS.
Structure, 25, 2017
5JUC
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CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MN2+, URIDINE-DIPHOSPHATE (UDP) AND GLUCOSYL-3-PHOSPHOGLYCERATE (GPG) - GPGS*GPG*UDP*MN2+_2
Descriptor:Glucosyl-3-phosphoglycerate synthase, URIDINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL, ...
Authors:Albesa-Jove, D., Sancho-Vaello, E., Rodrigo-Unzueta, A., Comino, N., Carreras-Gonzalez, A., Arrasate, P., Urresti, S., Guerin, M.E.
Deposit date:2016-05-10
Release date:2017-05-24
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS.
Structure, 25, 2017
5JUD
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CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH URIDINE-DIPHOSPHATE (UDP) - GPGS*UDP
Descriptor:Glucosyl-3-phosphoglycerate synthase, URIDINE-5'-DIPHOSPHATE
Authors:Albesa-Jove, D., Sancho-Vaello, E., Rodrigo-Unzueta, A., Comino, N., Carreras-Gonzalez, A., Arrasate, P., Urresti, S., Guerin, M.E.
Deposit date:2016-05-10
Release date:2017-05-24
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS.
Structure, 25, 2017
4Y6N
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CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MN2+, URIDINE-DIPHOSPHATE-GLUCOSE (UDP-GLC) AND PHOSPHOGLYCERIC ACID (PGA) - GPGS MN2+ UDP-GLC PGA-1
Descriptor:Glucosyl-3-phosphoglycerate synthase, MANGANESE (II) ION, 3-PHOSPHOGLYCERIC ACID, ...
Authors:Albesa-Jove, D., Rodrigo-Unzueta, A., Cifuente, J.O., Urresti, S., Comino, N., Sancho-Vaello, E., Guerin, M.E.
Deposit date:2015-02-13
Release date:2015-07-15
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.348 Å)
Cite:A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase.
Angew.Chem.Int.Ed.Engl., 54, 2015
4Y6U
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MYCOBACTERIAL PROTEIN
Descriptor:Glucosyl-3-phosphoglycerate synthase, MANGANESE (II) ION, CHLORIDE ION, ...
Authors:Albesa-Jove, D., Rodrigo-Unzueta, A., Cifuente, J.O., Urresti, S., Comino, N., Sancho-Vaello, E., Guerin, M.E.
Deposit date:2015-02-13
Release date:2015-07-15
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.271 Å)
Cite:A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase.
Angew.Chem.Int.Ed.Engl., 54, 2015
4Y7F
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CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MN2+, URIDINE-DIPHOSPHATE-GLUCOSE (UDP-GLC) AND 3-(PHOSPHONOOXY)PROPANOIC ACID (PPA) - GPGS MN2+ UDP-GLC PPA
Descriptor:Glucosyl-3-phosphoglycerate synthase, MANGANESE (II) ION, 3-(phosphonooxy)propanoic acid, ...
Authors:Albesa-Jove, D., Rodrigo-Unzueta, A., Cifuente, J.O., Urresti, S., Comino, N., Sancho-Vaello, E., Guerin, M.E.
Deposit date:2015-02-14
Release date:2015-07-15
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (3.231 Å)
Cite:A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase.
Angew.Chem.Int.Ed.Engl., 54, 2015
4Y7G
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CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MN2+, URIDINE-DIPHOSPHATE-GLUCOSE (UDP-GLC) AND GLYCEROL 3-PHOSPHATE (G3P) - GPGS MN2+ UDP-GLC G3P
Descriptor:Glucosyl-3-phosphoglycerate synthase, MANGANESE (II) ION, SN-GLYCEROL-3-PHOSPHATE, ...
Authors:Albesa-Jove, D., Rodrigo-Unzueta, A., Cifuente, J.O., Urresti, S., Comino, N., Sancho-Vaello, E., Guerin, M.E.
Deposit date:2015-02-14
Release date:2015-07-15
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase.
Angew.Chem.Int.Ed.Engl., 54, 2015
4Y9X
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CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MN2+, URIDINE-DIPHOSPHATE-GLUCOSE (UDP-GLC) AND PHOSPHOGLYCERIC ACID (PGA) - GPGS MN2+ UDP-GLC PGA-3
Descriptor:Glucosyl-3-phosphoglycerate synthase, MANGANESE (II) ION, CHLORIDE ION, ...
Authors:Albesa-Jove, D., Rodrigo-Unzueta, A., Cifuente, J.O., Urresti, S., Comino, N., Sancho-Vaello, E., Guerin, M.E.
Deposit date:2015-02-17
Release date:2015-07-15
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.637 Å)
Cite:A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase.
Angew.Chem.Int.Ed.Engl., 54, 2015
5JQQ
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CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS - APO FORM
Descriptor:Glucosyl-3-phosphoglycerate synthase, GLYCEROL
Authors:Albesa-Jove, D., Urresti, S., Gest, P.M., van der Woerd, M., Jackson, M., Guerin, M.E.
Deposit date:2016-05-05
Release date:2016-12-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of glucosyl-3-phosphoglycerate synthase from Mycobacterium tuberculosis - apo form
To Be Published
4N9W
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CRYSTAL STRUCTURE OF PHOSPHATIDYL MANNOSYLTRANSFERASE PIMA
Descriptor:GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase, GUANOSINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL
Authors:Giganti, D., Albesa-Jove, D., Bellinzoni, M., Guerin, M.E., Alzari, P.M.
Deposit date:2013-10-21
Release date:2014-11-12
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Secondary structure reshuffling modulates glycosyltransferase function at the membrane.
Nat.Chem.Biol., 11, 2015
4NC9
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CRYSTAL STRUCTURE OF PHOSPHATIDYL MANNOSYLTRANSFERASE PIMA
Descriptor:GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase
Authors:Giganti, D., Albesa-Jove, D., Bellinzoni, M., Guerin, M.E., Alzari, P.M.
Deposit date:2013-10-24
Release date:2014-11-12
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (3.192 Å)
Cite:Secondary structure reshuffling modulates glycosyltransferase function at the membrane.
Nat.Chem.Biol., 11, 2015
4NXI
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RV2466C MEDIATES THE ACTIVATION OF TP053 TO KILL REPLICATING AND NON-REPLICATING MYCOBACTERIUM TUBERCULOSIS
Descriptor:Uncharacterized protein, MAGNESIUM ION, 1,2-ETHANEDIOL
Authors:Albesa-Jove, D., Urresti, S., Comino, N., Guerin, M.E.
Deposit date:2013-12-09
Release date:2014-10-22
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis.
Acs Chem.Biol., 9, 2014